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Broad Anti-Viral Capacities of Lian-Hua-Qing-Wen Capsule and Jin-Hua-Qing-Gan Granule and Rational use Against COVID-19 Based on Literature Mining

Mingfei Shi, Bo Peng, An Li, Ziyun Li, Ping Song, Jing Li, Ruodan Xu, Ning Li
<span title="2021-05-14">2021</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/qigargnicncadmdn56ei23yjnu" style="color: black;">Frontiers in Pharmacology</a> </i> &nbsp;
Both Lian-Hua-Qing-Wen Capsule (LHQWC) and Jin-Hua-Qing-Gan Granule (JHQGG) have been recommended by China Food and Drug Administration for the treatment of COVID-19 and have played a vital role in the  ...  ACKNOWLEDGMENTS Authors thank Zhenji LI, World Federation of Chinese Medicine Societies for his supports and valuable input.  ...  INTRODUCTION Lian-Hua-Qing-Wen Capsule and Jin-Hua-Qing-Gan Granule are Both Recommended as Effective "Chinese Solution" Against COVID-19 The novel coronavirus disease 2019 pandemics has reached almost  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fphar.2021.640782">doi:10.3389/fphar.2021.640782</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34054522">pmid:34054522</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8160462/">pmcid:PMC8160462</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/c3dlcbxa7bblfndchcr7kszuai">fatcat:c3dlcbxa7bblfndchcr7kszuai</a> </span>
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CVAE-GAN: Fine-Grained Image Generation through Asymmetric Training [article]

Jianmin Bao, Dong Chen, Fang Wen, Houqiang Li, Gang Hua
<span title="2017-10-12">2017</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
This kind of asymmetric loss function makes the GAN training more stable.  ...  GAN at different iterations.  ...  Our formulation: the CVAE-GAN In this section, we will introduce the proposed CVAE-GAN networks.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1703.10155v2">arXiv:1703.10155v2</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/n4ic2hubm5axbpp3dhuuisfjii">fatcat:n4ic2hubm5axbpp3dhuuisfjii</a> </span>
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Dietary Sources and Bioactivities of Melatonin

Xiao Meng, Ya Li, Sha Li, Yue Zhou, Ren-You Gan, Dong-Ping Xu, Hua-Bin Li
<span title="2017-04-07">2017</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ztxgyntcovcxnht5g4vkoge5ka" style="color: black;">Nutrients</a> </i> &nbsp;
Insomnia is a serious worldwide health threat, affecting nearly one third of the general population. Melatonin has been reported to improve sleep efficiency and it was found that eating melatonin-rich foods could assist sleep. During the last decades, melatonin has been widely identified and qualified in various foods from fungi to animals and plants. Eggs and fish are higher melatonin-containing food groups in animal foods, whereas in plant foods, nuts are with the highest content of
more &raquo; ... Some kinds of mushrooms, cereals and germinated legumes or seeds are also good dietary sources of melatonin. It has been proved that the melatonin concentration in human serum could significantly increase after the consumption of melatonin containing food. Furthermore, studies show that melatonin exhibits many bioactivities, such as antioxidant activity, anti-inflammatory characteristics, boosting immunity, anticancer activity, cardiovascular protection, anti-diabetic, anti-obese, neuroprotective and anti-aging activity. This review summaries the dietary sources and bioactivities of melatonin, with special attention paid to the mechanisms of action. Huge differences of melatonin concentrations were reported among various food species and/or organs, ranging from pg/g to mg/g [22, 23] . Additionally, it was well documented that the consumption of melatonin-rich foods may induce the potential health impacts by significantly increasing the serum melatonin concentration and antioxidant capacity in human beings [24] . Therefore, those foods containing melatonin are now popular and regarded as promising nutraceuticals [25] [26] [27] . Nutrients 2017, 9, 367 2 of 58 Nutrients 2017, 9, 367 3 of 64 times compared to that in the daytime [38]. Furthermore, melatonin was found in colostrum with the comparable concentration as it in plasma [39], which could benefit the newborns that lack the established rhythmic excretion of melatonin in the first couple of weeks in their lives [40]. Neither the artificial formulas nor the fermented milk drink were tested with detectable melatonin [41,42]. 2.2. Plant Foods 2.2.1. Cereals Cereals are largely consumed all around the world, in which melatonin contents were also investigated. Wang et al. studied melatonin contents in 58 cultivars of corns and 25 of rice, finding huge variety due to genotypes: 0-2034 ng/g (mean: 96.5 ng/g) for corns and 0-264 ng/g (mean: 16 ng/g) for rice [31] . Additionally, they also discovered the pigmented rice contained higher melatonin contents, which was consistent with the findings from Setyaningsih et al. [17] . Moreover, Setyaningsih et al. reported that the level of melatonin in nonglutinous black rice was almost twice as that in the glutinous type and the melatonin concentration was 1/3 less in polished rice compared to that in the whole ones. For other cereals such as wheat, barley and oats, melatonin was found relatively high, e.g., 124.7 ± 14.9 ng/g fresh weight (FW) in wheat, 82.3 ± 6.0 ng/g FW in barley and 90.6 ± 7.7 ng/g FW in oats, respectively [34] . In terms of bread, crumb was found with higher melatonin levels than the crust [20]. Fruits Generally, melatonin was found in many commonly consumed fruits. Grapes [43] , cherries [30] and strawberries [44] were the most popular ones in the investigation of melatonin contents, which also showed the difference between cultivars. The highest melatonin in three kinds of fruits was reported in the range of 8.9-158.9 ng/g DW in the skin of grapes (Vitis vinifera L. cv. Malbec) [45], 13.46 ± 1.10 ng/g FW in tart cherries (Prunus cerasus L. cv. Balaton) [46] , and 11.26 ± 0.13 ng/g FW in strawberry (Fragaria ananassa L. cv. Festival) [44] . Other fruits contained melatonin at a relatively low level. Vegetables Melatonin exists in lots of common vegetables, although it remains undetectable in potatoes and very low in beetroots [47, 48] . Tomatoes and peppers were the most studied vegetables, and they showed relatively high melatonin concentrations in the vegetable group, i.e., 11.9 ng/g FW or 93.4 ng/g DW in pepper (Capsicum annuum L. cv. F26) and 14.77 ng/g FW or 249.98 ng/g DW in tomato (Solanum lycopersicum L. cv. Optima) [49] , and 23.87 ± 2.02 ng/g FW in tomato (Lycopersicon esculentum cv. Bonda) [44] . Mushrooms also contain melatonin, e.g., 12,900 ± 770 ng/g DW in Basidiomycota (Lactarius deliciosus), 6800 ± 60 ng/g DW in Basidiomycota (Boletus edulis) [42] , and 4300-6400 ng/g DW in Agaricus bisporus [50]. Legumes and Seeds (Raw and Germinated) Melatonin occurred in many legumes and seeds, and in some particular seeds, such as white and black mustard seeds, melatonin was as high as 189 ng/g DW and 129 ng/g DW, respectively [51] . Moreover, the germination process of legumes and seeds was proved to be able to increase the melatonin levels significantly [52, 53] . For example, in germinated soybean seeds, the melatonin level reached a peak of 1.89 ± 0.11 ng/g DW during germination, which was 400% increase than that in raw soybean seeds [52] . Similarly, melatonin was observed more than 11 folds in the germinated mung bean seeds as it was in the raw ones [53] . Nutrients 2017, 9, 367 4 of 64 Nuts Melatonin was found in various nuts, and pistachio (Pistacia vera L.) was reported with the highest content (233,000 ng/g DW) to date [28]. Juices and Beverages The popular alcoholic drinks like beer [42, 54] and wine [55, 56] , were tested for melatonin, with 0.09 ± 0.01 ng/mL in beer [42] and up to 129.5 ± 3.5 ng/mL in wine [42, 54] . Besides the melatonin originated from the main ingredients, it was also considered to be synthesized during the fermentation process due to the yeast growth [54, 57] . As for the other drinks, coffee usually contains high concentration of melatonin because coffee beans contained melatonin at a very high level and even much higher in roasted beans [58] . Melatonin also existed in juices [43], cacao [42] and balsamic vinegars [59]. However, it was not found in concentrates [60] or in tea [42], including green tea and black tea. Medical Herbs Many medical herbs were analyzed and some of them contained melatonin at a level of more than 1000 ng/g DW [61, 62] . In Huang-qin (Scutellaria biacalensis) melatonin was significantly high as 7110 ng/g DW, and in St. John's Wort (Hypericum perforatum) melatonin concentration was 4490 ng/g DW in flowers and 1750 ng/g DW in leaves [29] . Besides, 108 Chinese medical herbs were quantified, and melatonin was more than 10 ng/g DW in 64 tested herbs [61]. Edible Oils Melatonin ranged 0.03-0.29 ng/g in the tested edible oils, among which refined linseed presented 0.29 ng/g and virgin soybean 0.19 ng/g [63, 64] . De la Puerta et al. also demonstrated that generally the melatonin levels in the refined olive and sunflower oil were about half of those in the extra virgin olive oil [63]. Yeast Melatonin was found ranging 2.2 ± 0.14 ng/g in yeast, particularly Saccharomyces cerevisae, which is widely used in bread baking and alcohol industry [22] . Collectively, melatonin has been found in lots of foods. In animal foods, eggs and fish are relatively rich in melatonin, whereas in plant foods, nuts contains the highest melatonin contents, and some cereals and germinated legumes or seeds are also with high contents of melatonin. Mushrooms are also high-melatonin foods. However, it should be pointed out that the data on content of melatonin in foods in Table 1 were obtained by different analytical methods. Thus, quality of these data depended on the pretreatment method of sample and the analytical method itself. For example, in terms of radioimmunoassay (RIA) and enzyme-linked immunoabsorbent assay (ELISA), melatonin content could be over-estimated as some other components in the foods might also react with the related antibodies and enzymes, resulting in the lower accuracy. In addition, high-performance liquid chromatograph with ultraviolet detector (HPLC-UV) has low sensitivity and selectivity. Although high-performance liquid chromatograph with fluorescence detector (HPLC-FD) has high sensitivity, its selectivity is also low. Thus, melatonin content could be over-estimated by HPLC-UV or HPLC-FD method. Generally, gas chromatography-mass spectrometry (GC-MS) and high-performance liquid chromatography-mass spectrometry (HPLC-MS) have high resolution and sensitivity. Therefore, the data obtained by GC-MS or HPLC-MS are more accurate than those obtained by other methods [65] . Nutrients 2017, 9, 367 5 of 64 2.3. Other Issues about Melatonin Intake 2.3.1. The Alternation of Endogenous Melatonin along Life Cycle It has been well-documented that the secretion and/or serum levels of melatonin alter through a human lifetime [66] [67] [68] . Specifically, the serum levels of endogenous melatonin during the day and at night were measured in 367 volunteers (210 males and 157 females), aged 3 days to 90 years [67] . The results of this study demonstrated that nighttime serum melatonin concentration was low during the first 6 months of life [27.3 ± 5.4 (±standard error, SE) pg/mL], then reached a peak (329.5 ± 42.0 pg/mL) at 1-3 years of age, followed by a huge drop to 62.5 ± 9.0 pg/mL in the group of aged 15-20 years, probably due to the body size expansion during childhood and puberty without an increase in the rate of secretion. Then an additional decline followed in adulthood until 70-90 year of age (29.2 ± 6.1 pg/mL), attributing to a degenerative pineal gland associated with aging. Overall, the alternations of nocturnal serum melatonin during lifetime showed a fragmentary and inconsistent manner. Meanwhile, daytime serum melatonin levels were low and not age-related. Bioavailability of Exogenous Melatonin Melatonin has been known and used to assist sleep disorders [8] or jet lag [69] as a dietary supplement or as a drug, and recently it has also been reported to synergize other drugs as an adjuvant to improve their efficiency or to attenuate their side effects [70] . Herein, the bioavailability of melatonin has been studied by some researchers. In a study in vivo among 12 healthy volunteers, melatonin was administrated intravenously (i.v.) by 2 mg and orally by 2 and 4 mg, and in neither of these two phases the difference in serum half-life was found [71] . This study revealed the poor absolute bioavailability of oral melatonin tablets in both dosages, which was approximately 15%, possibly because of the poor oral absorption, large first-pass metabolism, or combined. Moreover, another study was conducted with 12 young healthy volunteers (6 males, 6 females), with 250 µg oral solution of D 7 melatonin, a molecule in which seven hydrogen atoms are replaced by seven deuterium atoms. It was reported that the absolute bioavailability of melatonin ranged from 1% to 37% and higher in women (16.8% ± 12.7%) than in men (8.6% ± 3.9%). It was also observed that the apparent terminal half-life values were 36 ± 2 and 41 ± 10 min for males and females respectively, indicating the fast-release property of melatonin [72] . Besides, 7 healthy male volunteers (ages 31.1 ± 1.1) were given an ingestion of 3 mg melatonin, and a marked increase in serum melatonin (3561 ± 1201 pg/mL) was found within 20 min, followed by a gradual decrease, but the level still remained higher than the basal level at 240 min after the ingestion [73]. Benefits of Consuming Melatonin-Containing Foods
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/nu9040367">doi:10.3390/nu9040367</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28387721">pmid:28387721</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5409706/">pmcid:PMC5409706</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/krhigvajlrfppepepqvujtgk44">fatcat:krhigvajlrfppepepqvujtgk44</a> </span>
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Intersubband transitions in Al0.82In0.18N/GaN single quantum well

Yu-Zhou Wang, Ding Li, Lei Li, Ning-Yang Liu, Lei Liu, Wen-Yu Cao, Wei-Hua Chen, Xiao-Dong Hu
<span title="">2011</span> <i title="IOP Publishing"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kapc53e2wja5voiuscgjcvvkcm" style="color: black;">Chinese Physics B</a> </i> &nbsp;
The cluster lies at a local minimum in the 13 CO column density and 8 μm emission. We interpret this feature as a hole carved by the energetic winds of the evolving massive stars.  ...  . • 207, the cluster lies in roughly the same direction as the RSG clusters reported in Figer et al. (2006) and Davies et al. (2007) .  ...  The cluster lies near the 13 CO minimum, suggestive of a cavity blown by the stellar winds of the massive cluster members. Table 1 1 Cluster Members and Candidates Star No.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1088/1674-1056/20/9/094207">doi:10.1088/1674-1056/20/9/094207</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/rdpnymyqbbg3pkfzhbisqiiczq">fatcat:rdpnymyqbbg3pkfzhbisqiiczq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170812043717/http://www.astro.wisc.edu/glimpse/alexander_2009.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/9c/7a/9c7ac37ab1b5539b958a9f9b8e5673eb85185f76.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1088/1674-1056/20/9/094207"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> iop.org </button> </a>

Dimensionality reduction modeling and characteristic analysis of memristive circuit

Bao Bo-Cheng, Wang Chun-Li, Wu Hua-Gan, Qiao Xiao-Hua
<span title="">2014</span> <i title="Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/qwpj4mxjj5co7jk3dabstqt6t4" style="color: black;">Wuli xuebao</a> </i> &nbsp;
图 1 电路中, 电容和电感的元件特性关系式有 C 1 v 1 = q C 1 = C 1 dφ 1 dt , C 2 v 2 = q C 2 = C 2 dφ 2 dt , Li 3 = L dq 3 dt = −φ 2 .  ...  图 2 电路中, 忆阻、 电容和电感的元件特 性关系有 q 1 = φ 1 + φ 3 1 = φ 3 + φ 3 3 , q 2 = φ 2 + φ 3 2 , C 1 v 3 = q C 1 = C 1 dφ 3 dt , C 2 v 4 = q C 2 = C 2 dφ 4 dt , Li 5 = L dq 5 dt = φ L .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.7498/aps.63.020504">doi:10.7498/aps.63.020504</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/gggc2y2ofzfzbhaxzpfg3bpzwu">fatcat:gggc2y2ofzfzbhaxzpfg3bpzwu</a> </span>
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HRTEM investigation of high-reflectance AlN/GaN distributed Bragg-reflectors by inserting AlN/GaN superlattice

Zhen-Yu Li, Tien-Chang Lu, Hao-Chung Kuo, Shing-Chung Wang, Ming-Hua Lo, K.M. Lau
<span title="">2009</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/lendm3cgpbbhjnnuhzxlwa47ey" style="color: black;">Journal of Crystal Growth</a> </i> &nbsp;
The effect of ultra-thin AlN/GaN superlattice insertion layer was examined in detail by transmission electron microscopy, and indicated that the crack of AlN/GaN DBR can be suppress by inserting AlN/GaN  ...  The reflectivity of AlN/GaN DBR with ultra-thin AlN/GaN SLIL was measured and achieved blue peak reflectivity of 99.4% at 462 nm.  ...  AlN/GaN SLIL.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.jcrysgro.2009.01.098">doi:10.1016/j.jcrysgro.2009.01.098</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ockbkws6sbhgldk6z4fsnvfwmy">fatcat:ockbkws6sbhgldk6z4fsnvfwmy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170815090342/https://ir.nctu.edu.tw/bitstream/11536/27709/1/000267302900081.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ae/38/ae382442a15a22e3d1aee4c4c2638b4b6773d4d5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.jcrysgro.2009.01.098"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

GAN-powered Deep Distributional Reinforcement Learning for Resource Management in Network Slicing [article]

Yuxiu Hua, Rongpeng Li, Zhifeng Zhao, Xianfu Chen, Honggang Zhang
<span title="2019-11-20">2019</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Finally, we verify the performance of the proposed GAN-DDQN and Dueling GAN-DDQN algorithms through extensive simulations.  ...  We put forward a reward-clipping mechanism to stabilize GAN-DDQN training against the effects of widely-spanning utility values.  ...  Hua, Rongpeng Li and Honggang Zhang are with the College of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China (e-mail: {21631087, lirongpeng, hong-gangzhang}@zju.edu.cn  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1905.03929v3">arXiv:1905.03929v3</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/35o2adoacva3lekk62u3e5zzua">fatcat:35o2adoacva3lekk62u3e5zzua</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200906030642/https://arxiv.org/pdf/1905.03929v3.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a3/76/a37647e7c68311a2d7e5a9dc1db0a0997e0f0671.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1905.03929v3" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

A novel four-gene signature for predicting the prognosis of hepatocellular carcinoma

Ying Sun, Zhi-Yong Chen, Xia Gan, Hua Dai, Dan Cai, Rong-Hua Liu, Jian-Ming Zhou, Hong-Li Zhang, Zi-Hua Li, Qing-Qing Luo, Song Jiang, Ting Wang (+1 others)
<span title="2022-05-05">2022</span> <i title="Taylor &amp; Francis"> figshare.com </i> &nbsp;
To identify and utilize gene signatures for the prognostic evaluation of postoperative patients with hepatocellular carcinoma (HCC). The gene mRNA expression profiles and corresponding clinicopathological data of postoperative patients with HCC were downloaded from The Cancer Genome Atlas (TCGA) database. Highly differentially expressed genes (DEGs) in tumor tissues compared to adjacent tissues were identified, and their associations with the overall survival (OS) of HCC patients were analyzed.
more &raquo; ... The strongly associated genes were used to develop a prognostic score for the survival stratification of HCC, and the underlying mechanisms were analyzed using bioinformatics. A total of 376 DEGs were identified and four DEGs (ADH4, COL15A1, RET and KCNJ16) were independently associated with OS. A prognostic score derived from the four genes could effectively stratify HCC patients with different OS outcomes, independent of clinical parameters. Patients with high scores exhibited poorer OS than patients with low scores (HR 5.526, 95% CI: 2.451–12.461, p Four genes strongly associated with the prognosis of postoperative patients with HCC were identified, and the derived prognostic score was simple and valuable for overall survival prediction.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6084/m9.figshare.19719149.v1">doi:10.6084/m9.figshare.19719149.v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ke4jo2fvnjclvevubyzlehpyke">fatcat:ke4jo2fvnjclvevubyzlehpyke</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220506105028/https://s3-eu-west-1.amazonaws.com/pstorage-tf-iopjsd8797887/35021021/igas_a_2069476_sm2656.pdf?X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Credential=AKIAJ45OKHUICFE2DW6Q/20220506/eu-west-1/s3/aws4_request&amp;X-Amz-Date=20220506T105028Z&amp;X-Amz-Expires=10&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Signature=3464a67077edaf892a96f316f888c45d85063efa029d3ae4d3c07b912c256bf1" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/80/37/80377c69333bde766ed1a7f8ab34ccdee18d163b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6084/m9.figshare.19719149.v1"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> figshare.com </button> </a>

Microstructural study of MBE-grown ZnO film on GaN/sapphire (0001) substrate

Hua Li, Jianping Sang, Chang Liu, Hongbing Lu, Juncheng Cao
<span title="2008-01-01">2008</span> <i title="Walter de Gruyter GmbH"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/r4ecuox7yrdy7h75vf7dx5nbau" style="color: black;">Open Physics</a> </i> &nbsp;
Ga2O3 is introduced into the ZnO/GaN heterostructure intentionally by oxygen-plasma pre-exposure on the GaN surface prior to ZnO growth.  ...  AbstractSingle crystalline ZnO film is grown on GaN/sapphire (0001) substrate by molecular beam epitaxy.  ...  It is clear to see the interfaces of ZnO/GaN and GaN/GaN buffer layer, which are indicated by black arrows.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2478/s11534-008-0032-2">doi:10.2478/s11534-008-0032-2</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/nk32skgpzjgf5gjo7hss4lcys4">fatcat:nk32skgpzjgf5gjo7hss4lcys4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180727000619/https://www.degruyter.com/downloadpdf/j/phys.2008.6.issue-3/s11534-008-0032-2/s11534-008-0032-2.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c4/d1/c4d158ceb2291e88b75275f71e63ea3b3e28d303.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2478/s11534-008-0032-2"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Carrier localization degree of In0.2Ga0.8N/GaN multiple quantum wells grown on vicinal sapphire substrates

Zhen-Yu Li, Ming-Hua Lo, Ching-Hua Chiu, Po-Chun Lin, Tien-Chang Lu, Hao-Chung Kuo, Shing-Chung Wang
<span title="">2009</span> <i title="AIP Publishing"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/cx63fwaifnhdtbqbjlraxrufii" style="color: black;">Journal of Applied Physics</a> </i> &nbsp;
8 cm −2 and reduced to 3.0ϫ 10 8 cm −2 at the top of n-GaN layer.  ...  The optical analysis confirmed that the In 0.2 Ga 0.8 N / GaN MQWs grown on 0.2°-off sapphire substrate exhibited the smallest carrier localization degree and more ordered In 0.2 Ga 0.8 N / GaN MQW structure  ...  N / GaN MQW LEDs comprise a 50-nm-thick GaN buffer layer, a 2-m-thick undoped GaN epilayer, a 2-m-thick n-GaN epilayer, a fivepair In 0.02 Ga 0.98 N / GaN prestrained layer, a five-pair a͒ Electronic mail  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1063/1.3055264">doi:10.1063/1.3055264</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ftta7u5jh5a2tcpwj4y4ds2fwu">fatcat:ftta7u5jh5a2tcpwj4y4ds2fwu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170809150016/http://www.ieo.nctu.edu.tw/sclab/2009/(22)Carrier%20localization%20degree%20of.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d6/9a/d69a911713116832dd1e8af97ce434c48cc0ab52.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1063/1.3055264"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Kuwanon G protects HT22 cells from advanced glycation end product-induced damage

Wen-Jun Gan, Chen-Lin Gao, Wen-Qian Zhang, Jun-Ling Gu, Ting-Ting Zhao, Heng-Li Guo, Hua Zhou, Yong Xu, Li-Li Yu, Li-Fang Li, Ding-Kun Gui, You-Hua Xu
<span title="2021-02-25">2021</span> <i title="Spandidos Publications"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zpl7c47akvfnhjqqqfeeqzmgnu" style="color: black;">Experimental and Therapeutic Medicine</a> </i> &nbsp;
The incidence of diabetic encephalopathy is increasing as the population ages. Evidence suggests that formation and accumulation of advanced glycation end products (AGEs) plays a pivotal role in disease progression, but limited research has been carried out in this area. A previous study demonstrated that Kuwanon G (KWG) had significant anti-oxidative stress and anti-inflammatory properties. As AGEs are oxidative products and inflammation is involved in their generation it is hypothesized that
more &raquo; ... WG may have effects against AGE-induced neuronal damage. In the present study, mouse hippocampal neuronal cell line HT22 was used. KWG was shown to significantly inhibit AGE-induced cell apoptosis in comparison with a control treatment, as determined by both MTT and flow cytometry. Compared with the AGEs group, expression of pro-apoptotic protein Bax was reduced and expression of anti-apoptotic protein Bcl-2 was increased in the AGEs + KWG group. Both intracellular and extracellular levels of acetylcholine and choline acetyltransferase were significantly elevated after KWG administration in comparison with controls whilethe level of acetylcholinesterase decreased. These changes in protein expression were accompanied by increased levels of superoxide dismutase and glutathione peroxidase synthesis and reduced production of malondialdehyde and reactive oxygen species. Intracellular signaling pathway protein levels were determined by western blot and immunocytochemistry. KWG administration was found to prevent AGE-induced changes to the phosphorylation levels of Akt, IκB-α, glycogen synthase kinase 3 (GSK3)-α and β, p38 MAPK and NF-κB p65 suggesting a potential neuroprotective effect of KWG against AGE-induced damage was via the PI3K/Akt/GSK3αβ signaling pathway. The findings of the present study suggest that KWG may be a potential treatment for diabetic encephalopathy.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3892/etm.2021.9869">doi:10.3892/etm.2021.9869</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33747164">pmid:33747164</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7967837/">pmcid:PMC7967837</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/o7rvmmfppvguxk55swbyz7l2bi">fatcat:o7rvmmfppvguxk55swbyz7l2bi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210301094518/https://www.spandidos-publications.com/10.3892/etm.2021.9869/download" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a1/85/a1857b7ce5834ab28b2fcd5b14f97124f636c07b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3892/etm.2021.9869"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967837" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Another New Alkaloid from Corydalis impatiens

Ji Chang Li, Yue Hua Lin, Yong Hou, Ping Li, Chun Tao Xu, Gan Peng Li
<span title="">2013</span> <i title="Asian Journal of Chemistry"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/64p6ou7nvfevbdpianqf6sywei" style="color: black;">Asian Journal of Chemistry</a> </i> &nbsp;
Gan-Peng Li in Yunnan University of Nationalities.A voucher specimen was deposited in our laboratory of school of chemistry and biotechnology.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.14233/ajchem.2013.13321">doi:10.14233/ajchem.2013.13321</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/tenp46m3fvfxtdtumdoxalcpdq">fatcat:tenp46m3fvfxtdtumdoxalcpdq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220304060805/https://asianjournalofchemistry.co.in/User/ViewFreeArticle.aspx?ArticleID=25_1_126" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/06/3d/063d00e462bdd8306f855c9ec4b6406772f1e0d3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.14233/ajchem.2013.13321"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Dietary Natural Products for Prevention and Treatment of Breast Cancer

Ya Li, Sha Li, Xiao Meng, Ren-You Gan, Jiao-Jiao Zhang, Hua-Bin Li
<span title="2017-07-08">2017</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ztxgyntcovcxnht5g4vkoge5ka" style="color: black;">Nutrients</a> </i> &nbsp;
Breast cancer is the most common cancer among females worldwide. Several epidemiological studies suggested the inverse correlation between the intake of vegetables and fruits and the incidence of breast cancer. Substantial experimental studies indicated that many dietary natural products could affect the development and progression of breast cancer, such as soy, pomegranate, mangosteen, citrus fruits, apple, grape, mango, cruciferous vegetables, ginger, garlic, black cumin, edible macro-fungi,
more &raquo; ... nd cereals. Their anti-breast cancer effects involve various mechanisms of action, such as downregulating ER-α expression and activity, inhibiting proliferation, migration, metastasis and angiogenesis of breast tumor cells, inducing apoptosis and cell cycle arrest, and sensitizing breast tumor cells to radiotherapy and chemotherapy. This review summarizes the potential role of dietary natural products and their major bioactive components in prevention and treatment of breast cancer, and special attention was paid to the mechanisms of action.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/nu9070728">doi:10.3390/nu9070728</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28698459">pmid:28698459</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5537842/">pmcid:PMC5537842</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/m5bmwubyvjbobfu7eakr4lblrm">fatcat:m5bmwubyvjbobfu7eakr4lblrm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180730034212/https://res.mdpi.com/def50200928f8eef05e6db8d110a3e540a2666f7da39e918145f022c0178af1b83282893d137da3600a7a2e3221cd2b859371b422ff593f8c71f55c82c90467a839200603d348cc13ee64ca3be29fded66e758fdb19084044d7e734cf5ed58d78bcca670bdb38854d337f0c7819113b385fe69cde35b7127c399506dc3c01a4fbff890cb383802489b9da257e3b33fe5fc6236f516077694fc?filename=&amp;attachment=1" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d5/15/d5153938aef49b97c0e8228c398b4e2dd8d7e4e0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/nu9070728"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537842" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Synthesis and electrochemical performance of Na-modified Li2Fe0.5Mn0.5SiO4 cathode material for Li-ion batteries

Ming Li, Lu-Lu Zhang, Xue-Lin Yang, Hua-Bin Sun, Yun-Hui Huang, Gan Liang, Shi-Bing Ni, Hua-Chao Tao
<span title="">2015</span> <i title="Royal Society of Chemistry (RSC)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/x6heqyfrkfhzlnbbt24hnmjoda" style="color: black;">RSC Advances</a> </i> &nbsp;
Li + /Li).  ...  high theoretical capacity (166 mA h g À1 for one Li + ion exchange, and 332 mA h g À1 for two Li + ions exchange).  ...  Conclusions Li 2Àx Na x Fe 0.5 Mn 0.5 SiO 4 /C composites were successfully synthesized via a reuxing-assisted solid-state reaction, and its electrochemical performance was also investigated.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1039/c5ra02129d">doi:10.1039/c5ra02129d</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/l4l6uqyonrfezi26ixoi6wtd4u">fatcat:l4l6uqyonrfezi26ixoi6wtd4u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170810002903/http://www.shsu.edu/~phy_gnl/PDF-file-Gan-articles/2015-Na-modified%20Li-Fe-Mn-SiO4%20cathode%20material.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f2/a3/f2a322c4744f0306dd6876c51507b0ac97ef2f24.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1039/c5ra02129d"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Supplementary document for Room-Temperature Polariton Lasing in GaN Microrod with Large Rabi Splitting - 5715516.pdf

Huanqing Chen, Junchao Li, Guo Yu, Hua Zong, Rui Lang, Menglai Lei, Shukun Li, Muhammad Khan, Yue Yang, Tiantian Wei
<span title="2022-04-29">2022</span> <i title="Optica Publishing Group"> figshare.com </i> &nbsp;
Supplemental Document
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6084/m9.figshare.19632879.v1">doi:10.6084/m9.figshare.19632879.v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ruxz4gblhfa3dftg6dtc3ockly">fatcat:ruxz4gblhfa3dftg6dtc3ockly</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220430222026/https://s3-eu-west-1.amazonaws.com/pstorage-osa-2151918321/34869621/5715516.pdf?X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Credential=AKIAIC5UZOEV5G5EP3CQ/20220430/eu-west-1/s3/aws4_request&amp;X-Amz-Date=20220430T222025Z&amp;X-Amz-Expires=10&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Signature=12bcb106381dbf2b2c11956896a18c99876327e8be8ead813b6e4f817364df87" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/46/df/46dff0d6384b977c2a8dd5acec82c4ce959f3e6a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6084/m9.figshare.19632879.v1"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> figshare.com </button> </a>
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