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Levodopa reinstates connectivity from prefrontal to premotor cortex during externally paced movement in Parkinson's disease

Damian M. Herz, Hartwig R. Siebner, Oliver J. Hulme, Esther Florin, Mark S. Christensen, Lars Timmermann
2014 NeuroImage  
We thank the volunteers for participating in this study.  ...  Acknowledgments We wish to thank C. Reck, M.T. Barbe and M.K. Tscheuschler for help with EEG recordings as well as clinical ratings and M.  ...  Introduction Patients with Parkinson's disease (PD) exhibit difficulties in initiating and executing movements (Lang and Lozano, 1998a,b) .  ... 
doi:10.1016/j.neuroimage.2013.11.023 pmid:24269570 fatcat:6wkz7vjcebcsbo6kjwaq4hbhxa

Functional imaging correlates of akinesia in Parkinson's disease: Still open issues

Charlotte Spay, Garance Meyer, Marie-Laure Welter, Brian Lau, Philippe Boulinguez, Bénédicte Ballanger
2019 NeuroImage: Clinical  
Akinesia is a major manifestation of Parkinson's disease (PD) related to difficulties or failures of willed movement to occur.  ...  We adhere to a use of the term akinesia restricted to dysfunctions of movement initiation, ranging from delayed response to freezing or even total abolition of movement.  ...  HC > AR Decreased fMRI signal in the rostral part of the SMA, in the right dorsolateral prefrontal cortex, in the left lateral premotor cortex and left inferior parietal cortex.  ... 
doi:10.1016/j.nicl.2018.101644 pmid:30584015 pmcid:PMC6412010 fatcat:n2l2g6kdfjccnptroiihhkjqfa

Trends in Technology Usage for Parkinson's Disease Assessment: A Systematic Review [article]

Ranadeep Deb, Ganapati Bhat, Sizhe An, Umit Ogras, Holly Shill
2021 medRxiv   pre-print
The trend shows the growing interest in assessing Parkinson's Disease with wearable devices in the last decade, particularly in the last 4 years.  ...  Parkinson's disease (PD) is a neurological disorder with complicated and disabling motor and non-motor symptoms.  ...  Timmermann, "Levodopa reinstates connectivity from prefrontal to 551 premotor cortex during externally paced movement in parkinson's disease," Neuroimage, vol. 90, pp. 15-23, 2014. 552 [45] V.  ... 
doi:10.1101/2021.02.01.21250939 fatcat:hrilm4tumbayhaojeansjpjmam

Abstracts Presented at the Thirty–Fourth Annual International Neuropsychological Society Conference, February 1–4, 2006, Boston, Massachussetts, USA

2006 Journal of the International Neuropsychological Society  
Objective: Response inhibition (RI) is mediated by prefrontal cortex, its circuitry, and associated cortical regions that are vulnerable in traumatic brain injury (TBI).  ...  Previous investigations using functional magnetic resonance imaging (fMRI) during RI have reported different activation patterns in patients with TBI, relative to control subjects.  ...  are impaired in a Parkinson's Disease sample.  ... 
doi:10.1017/s1355617706069918 fatcat:cy3cbwlgrvccfnn6w7inplceni

Abstracts of the 20th European Conference on Eye Movements, 18-22 August 2019, in Alicante (Spain)

Susana Martinez-Conde, Luis Martinez-Otero, Albert Compte, Rudolf Groner
2019 Journal of Eye Movement Research  
This document contains all abstracts of the 20th European Conference on Eye Movements, August 18-22, 2019, in Alicante, Spain Video stream "Glimpses at 20th ECEM":  ...  Higher dopamine levels led to faster simple reaction times but not choice reaction times and a trend towards higher reward sensitivity was observed. Data collection is currently ongoing.  ...  Parkinson's disease (PD) is a slowly progressive neurodegenerative disease where the gradual death of dopaminergic cells in the substanta nigra and consequent loss of dopaminergic projections to the striatum  ... 
doi:10.16910/jemr.12.7.1 pmid:33828763 pmcid:PMC7917478 fatcat:wqzwn552cndsnablyikzx3og5e

The cortical mechanisms underlying human spatial navigation: from afferent processing to motor efference

Diego Kaski, Adolfo Bronstein, Barry Seemungal
This technique was then applied in combination with physical therapy to patients with Parkinson"s disease (Chapter 6) and patients with small vessel disease (Chapter 7) – a c [...]  ...  position, motion, and timing perception during angular rotations in the dark.  ...  Further studies are needed to evaluate the therapeutic use of non-invasive brain stimulation during music rehabilitation in patients with Parkinson"s disease, in particular the effect of repeated sessions  ... 
doi:10.25560/14673 fatcat:rjdk4cnq6jc7bkxonq62y2tmxu

Bayesian modeling of brain function and behavior

Maya Anna Jastrzebowska
Acknowledgments, Funding and Financial Disclosure Statement We would like to thank all those who participated in the study, Dr Deepa Pothalil and Dr Elisabeth Roggenhofer for clinical evaluations.  ...  During the scan, participants lay supine in the scanner and performed an externally-paced motor task.  ...  Within a block, movements were externally paced at a frequency of 0.5 Hz by means of visual cues in the form of symbols representing the limb to be moved.  ... 
doi:10.5075/epfl-thesis-7388 fatcat:ypuovx46svhttmwjvup57msbla

Review Articles-Epidemiology and Management of ALS; Functional Imaging of Movement Disorders Management Topic-The Management of Patients with Head Injury Cognitive Primer-Agnosia Rehabilitation Article-Sonographic Imaging for Guiding Botulinum Toxin Injections in Limb Muscles International editorial liaison committee

Riccardo Soffietti, Italy, S Giovanni
7 and that activation of the dorsal prefrontal cortex in normal and PD subjects occurs only when making self-paced and not cued movements. 7 The lateral parietal and premotor areas, regions targeted  ...  All have been shown to increase SMA resting rCBF or activation during arm or finger movements with reduced bradykinesia. 11 In addition restoration of activation of SMA and prefrontal cortex during a  ...  neurons in Parkinson's disease (PD)?  ... 


Alexe Ioana, Grigore Vasilica, Larion Alin, Alexe Dan Iulian, Dolinschi Cristina, Mareş Gabriel
2012 Romania The journal is indexed in: Ebsco, SPORTDiscus, INDEX COPERNICUS JOURNAL MASTER LIST   unpublished
High performance in track and field is constantly conditioned by the athletes' reaction to different stress factors.  ...  The analysis of mental stress on athletes in different situations has made certain specialists to say that the psychological effect of a stress agent (seen as a response of the athlete) is less predictable  ...  These data suggest that the route from sensory input to cerebellum to premotor cortex could compensate for the decreased function of the route via the basal ganglion to the premotor cortex.  ...