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Language Processing in Frontotemporal Dementia: A Brief Review

Jonathan E. Peelle, Murray Grossman
2008 Language and Linguistics Compass  
Frontotemporal dementia (FTD) is a neurodegenerative condition that presents with a number of distinct behavioral phenotypes.  ...  SOC/EXEC patients' limited executive resources impact language processing in a variety of ways, including slowed grammatical processing and impaired narrative discourse.  ...  His research focuses on language processing and cortical plasticity in healthy aging and neurodegenerative disease.  ... 
doi:10.1111/j.1749-818x.2007.00047.x fatcat:gamazwoc6jdgzblfawbhs4rwky

Dementia: a brief review

Hillel Grossman, Christine Bergmann, Susan Parker
2006 The Mount Sinai journal of medicine  
Alzheimer's disease alone now affects 4.5 million people in the US, while millions more are currently affected by vascular dementia, Lewy Body disease and frontotemporal dementia.  ...  Dementia is an increasingly common diagnosis in our aging population, and the numbers are expected to rise exponentially in coming years.  ...  Dementia: A Brief Review HILLEL GROSSMAN, M.D.!2, CHRISTINE BERGMANN, M.D., PH.D.'!  ... 
pmid:17195884 fatcat:q5o5unfbu5f2zjwpbaynzqneny

Neuroimaging in Dementia: A Brief Review

Dipanjan Banerjee, Abilash Muralidharan, Abdul Rub Hakim Mohammed, Bilal Haider Malik
2020 Cureus  
Dementia is a clinical syndrome that manifests itself with impairment in cognitive functions owing to various neurodegenerative etiologies causing severe disability in the older population.  ...  We used PubMed as search engines to look for helpful articles; most of the sources used were peer reviewed.  ...  A few examples of etiologies include AD, vascular dementia (VaD), frontotemporal dementia (FTD), dementia due to Lewy body (DLB), and dementia due to Parkinson's disease [5] .  ... 
doi:10.7759/cureus.8682 pmid:32699682 pmcid:PMC7370590 fatcat:lsehl6ftjrhgxevjhoh7wq77yq

Verb agreements during on-line sentence processing in Alzheimer's disease and frontotemporal dementia☆

Catherine C. Price, Murray Grossman
2005 Brain and Language  
(AD, n D 15) and Frontotemporal Dementia (FTD, n D 14).  ...  AD, FTD, and control participants (n D 17) were asked to listen for a word in a sentence.  ...  (AD) and Frontotemporal Dementia (FTD).  ... 
doi:10.1016/j.bandl.2004.12.009 pmid:15896395 fatcat:lu5veud2fndrdkvspgmfva63qm

Language capacities in dementia

2013 Swiss Archives of Neurology and Psychiatry  
In PD, language difficulties have been reported only recently (for a review see [21] ).  ...  Key words: language; dementias Review article Review article nance imaging (MRI) and functional MRI (fMRI) have p rovided a new understanding of the language network that not only encompasses classic language  ... 
doi:10.4414/sanp.2013.00208 fatcat:xskzvdlgrjgfhh5y6zuykudfoe

Frontotemporal Dementias

Elizabeth C. Finger
2016 Continuum. Lifelong Learning in Neurology  
Patients with a flat affect may appear apathetic and lack spontaneous speech, giving only brief one-to twoword responses to questions despite preserved language abilities. Although KEY I.  ...  TABLE 5 - 5 7 Treatment Approaches for Behavioral Symptoms in Frontotemporal Dementia a bvFTD = behavioral variant of frontotemporal dementia; NA = not available; SSRIs = selective serotonin reuptake inhibitors  ... 
doi:10.1212/con.0000000000000300 pmid:27042904 pmcid:PMC5390934 fatcat:qe76goomqrgijc7y5xuhbwz67m


Silvia Duong, Tejal Patel, Feng Chang
2017 Canadian Pharmacists Journal / Revue des Pharmaciens du Canada  
Acknowledgments: The authors thank Mo Chen, MSc candidate at the University of Waterloo, for assistance in editing the section on assessment tools and generating Table 3 and Joe Petrik for copyediting  ...  , a mechanism involved in the neurodegenerative process of AD (Table 4 ).  ...  depression. 5, [24] [25] [26] [27] A medication review and review of systems should be part of the evaluation.  ... 
doi:10.1177/1715163517690745 pmid:28405256 pmcid:PMC5384525 fatcat:gbsbbdttuncqlfipcdfgqbl2d4

Frontotemporal Dementia

Nicholas T. Olney, Salvatore Spina, Bruce L. Miller
2017 Neurologic clinics  
Frontotemporal Dementia (FTD) is a heterogeneous disorder with distinct clinical phenotypes associated with multiple neuropathologic entities.  ...  Presently, the term FTD encompasses clinical disorders that include changes in behavior, language, executive control and often motor symptoms.  ...  A brief history of Frontotemporal Dementia In 1892, Pick, a Czech neurologist, provided the first known description of a patient with FTD (Pick, 1892) .  ... 
doi:10.1016/j.ncl.2017.01.008 pmid:28410663 pmcid:PMC5472209 fatcat:ibdb3aucgfcvhpb3ge57sqg7om

Brief cognitive screening instruments for early detection of Alzheimer's disease: a systematic review

Ellen Elisa De Roeck, Peter Paul De Deyn, Eva Dierckx, Sebastiaan Engelborghs
2019 Alzheimer's Research & Therapy  
The objective of this systematic review was (1) to give an overview of the available short screening instruments for the early detection of Alzheimer's disease (AD) and (2) to review the psychometric properties  ...  For each individual, a profile is constructed that indicates the likelihood that their impairment is due to AD versus frontotemporal dementia.  ...  * Duration in minutes Memory Language Orientation Executive functions Praxis Visuospatial abilities Attention Cogstate Brief Battery [58] Yes 12-15 Table 5 5 Overview of the psychometric properties  ... 
doi:10.1186/s13195-019-0474-3 pmid:30819244 pmcid:PMC6396539 fatcat:szzvhpvugjfu5jbzgzrzmafhnu

Olfactory dysfunction in dementia

Jorge Alves
2014 World Journal of Clinical Cases  
In this work, we provide a brief review of current research related to the olfactory dysfunction profiles in different types of dementia.  ...  Many age-related dementia, such as Alzheimer's disease, Vascular dementia, Parkinson's disease, and Frontotemporal Dementia often display olfactory dysfunction.  ...  brain regions involved in olfactory processing, and neurochemical changes in the brain (for a detailed review see Doty and Kamath [10] ).  ... 
doi:10.12998/wjcc.v2.i11.661 pmid:25405189 pmcid:PMC4233420 fatcat:pacdwq33yzeojboc7tarwrmuhi

Early diagnosis of dementia: neuropsychology

Florence Pasquier
1999 Journal of Neurology  
typical Alzheimer's disease, frontotemporal dementia, primary progressive aphasia, semantic dementia, Lewy body dementia, subcortical dementia, and vascular dementia.  ...  is a core feature of dementia, while memory complaints are not always due to a memory disorder, e.g., in anxiety disorders), and (b) characterizing the memory disorder in the context of cognitive neuropsychology  ...  Gregory CA, Orrell M, Sahakian B, Hodges JR (1997) Can frontotemporal dementia and Alzheimer's disease be differentiated using a brief battery of tests? Int J Geriat Psychiatry 12 : 375-383 31.  ... 
doi:10.1007/s004150050299 pmid:9987708 fatcat:54k77svbijeg7nt33ol4e6zuk4

Diagnosis and treatment of dementia: 2. Diagnosis

H. H. Feldman, C. Jacova, A. Robillard, A. Garcia, T. Chow, M. Borrie, H. M. Schipper, M. Blair, A. Kertesz, H. Chertkow
2008 CMAJ - Canadian Medical Association Journal  
It involves a clinical history (from patient and caregiver), a physical examination and brief cognitive testing. A list of core laboratory tests is recommended.  ...  Interpretation: The diagnosis of dementia remains clinically integrative based on history, physical examination and brief cognitive testing. A number of core laboratory tests are also recommended.  ...  between dementia subtypes, for instance, in suggesting that there might be frontotemporal dementia rather than Alzheimer disease  ... 
doi:10.1503/cmaj.070798 pmid:18362376 pmcid:PMC2267847 fatcat:jmd4fsvmjrgehmqbhkn7l6cviu

Suspecting dementia: canaries, chameleons and zebras

Jeremy C S Johnson, Laura McWhirter, Chris J D Hardy, Sebastian J Crutch, Charles R Marshall, Catherine J Mummery, Jonathan D Rohrer, Martin N Rossor, Jonathan M Schott, Rimona S Weil, Nick C Fox, Jason D Warren
2021 Practical Neurology  
Dementia is increasingly the business of neurologists and, with ageing populations worldwide, will become even more so in future.  ...  Here we outline a practical, symptom-led, bedside approach to suspecting dementia and its likely diagnosis, inspired by clinical experience and based on recognition of characteristic syndromic patterns  ...  All authors contributed significantly to the content of the manuscript and reviewed the drafts and provided feedback.  ... 
doi:10.1136/practneurol-2021-003019 fatcat:il6ck6htifay7jvxq2gp4znb7q

Semantic dementia: a unique clinicopathological syndrome

John R Hodges, Karalyn Patterson
2007 Lancet Neurology  
Semantic dementia (SD), one of the main clinical variants of frontotemporal dementia, presents a unique combination of clinical and imaging abnormalities.  ...  The distinctive and consistent neuropsychological defi cits in this disorder have had a major eff ect on current conceptions of the organisation of semantic memory and its links to episodic memory, language  ...  Review Many people view frontotemporal dementia, in all its forms, as a presenile disorder with onset typically between the ages of 45 and 65 years.  ... 
doi:10.1016/s1474-4422(07)70266-1 pmid:17945154 fatcat:syo2r252wre4ndejgvoupdv73q

A Comprehensive Update on Frontotemporal Dementia Frontotemporal Dementia Syndromes. John R. Hodges (Ed.). 2007. Cambridge, UK: Cambridge University Press, 346 pp., $110.00/£55.00 (HB)

Lynn A. Schaefer
2008 Journal of the International Neuropsychological Society  
., Kertesz, A., Robert, P.H., Albert, M., Boone, K., Miller, B.L., Cummings, J., & Benson, D.F. (1998). Frontotemporal lobar degeneration. Neurology, 51, 1546-1554.  ...  In conclusion, Frontotemporal Dementia Syndromes is a comprehensive resource for neuropsychologists, particularly those specializing in dementia, and would be a useful reference text in their libraries  ...  Harder to find is a book devoted exclusively to frontotemporal dementia (FTD), particularly a recent publication.  ... 
doi:10.1017/s1355617708081319 fatcat:rbzlskfqizhblgdb5tbekfptdu
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