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Landscape and variation of novel retroduplications PLOS Computational Biology | https://doi. ... Here, we performed comprehensive discovery and analysis of retroduplications in a large cohort of 2,535 individuals from 26 human populations, as part of 1000 Genomes Phase 3. ... We thank the Yale Center for Research Computing (YCRC) and the Ohio Supercomputer Center (OSC) for support and use of the research computing infrastructures. ...doi:10.1371/journal.pcbi.1005567 pmid:28662076 pmcid:PMC5510864 fatcat:6tobxfq5n5dv3chlwbsysyzx6y
, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. ... Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http:// creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution ... in a population. ...doi:10.1007/s10577-017-9569-5 pmid:29332159 pmcid:PMC5857280 fatcat:fqxw4u6zvrhbve4r3k5eyq2mr4
A high degree of natural variation was observed in both Fv1 and Fv7 and, on top of positive selection at certain residues, insertions and deletions were present that changed the length of the reading frames ... We surveyed the Fv1 genes of wild mice trapped in Thailand and characterized their restriction activities against a panel of retroviruses. ... Thus, the variation seen truly reflects genetic variation in the natural population, with heterozygosity frequently observed for both genes. ...doi:10.1371/journal.pgen.1008471 pmid:32525879 fatcat:57ql7yogtbhklkrvua4gx3m4na
in humans. ... Gene retroposition is known to contribute to patterns of gene evolution and adaptations. ... Gerstein, Landscape and variation of novel retroduplications in PLoS Comput. Biol. 13, e1005567 (2017). . H. ...doi:10.1101/2020.08.06.239277 fatcat:67do22m47naxxgcref7bnh7emq
The full abstract for this thesis is available in the body of the thesis, and will be available when the embargo expires. ... Acknowledgements I would like to thank my supervisor, Keith Adams, for giving me the excellent opportunity to study several interesting questions in plant genome evolution as well as his great guidance ... This finding was further supported by another study where genes localized in CNV (copy number variation) regions were shown to have more miRNA-predicted targets in human (Felekkis et al. 2011 ). ...doi:10.14288/1.0357061 fatcat:ugce6r5x45e6dnucq35ke7pr7e