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FindYourHelp: an expert finder module on Virtual Learning Environments
2012
Informática na educação: teoria & prática
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Um estudo de viabilidade da solução foi desenvolvido e evidenciou a aplicabilidade da ferramenta em relação a seus objetivos iniciais. ...
Este artigo discute a criação de um módulo adicional para o ambiente Moodle, que permita a identificação automática de especialistas que contribuam em seus fóruns de discussão. ...
The tool was developed in PHP and as PHP has no native support for parallel processing threads of execution (multithreading) and so we could not improve the execution time of the tool by using parallel ...
doi:10.22456/1982-1654.14156
fatcat:md5uqacyzfetpc67i77vrb7whm
Isotope stratigraphy of the Lapa Formation, São Francisco Basin, Brazil: Implications for Late Neoproterozoic glacial events in South America
2006
Precambrian Research
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Four boreholes, spanning different depositional settings, were sampled at highresolution and investigated for their petrographic and chemical criteria to evaluate their degree of preservation. ...
The Lapa Formation is a thick carbonate sequence (∼900 m) that constitutes the upper part of the Vazante Group on the São Francisco craton, Brazil. ...
Veizer, and an anonymous reviewer for their constructive reviews and Votorantim Metais (Vazante, Minas Gerais, Brazil) for providing field assistance. ...
doi:10.1016/j.precamres.2006.07.001
fatcat:zwjiyh3sejghjb24yxikwgbbl4
11C-Methionine-PET: A novel and sensitive tool for monitoring of early response to treatment in multiple myeloma
2015
OncoTarget
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However, new treatment modalities and novel drugs have been introduced and thus additional tools for therapy monitoring are increasingly needed. ...
Therefore, we evaluated the radiotracers 11 C-Methionine (paraprotein-biosynthesis) and 18 F-FDG (glucose-utilization) for monitoring response to anti-myeloma-therapy and outcome prediction. ...
In addition, PET/CT was recently reported to be a very useful tool for monitoring of anti-myeloma therapy (12) . ...
doi:10.18632/oncotarget.3053
pmid:25762625
pmcid:PMC4480763
fatcat:qobvmo27hrhpxhq66ywljynvjy
Stability of ground state degeneracy to long-range interactions
[article]
2021
arXiv
pre-print
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For these models we prove (1) the stability of the gap, and (2) that the residual splitting of the low-energy states below the gap is exponentially small in the system size. ...
We show that some gapped quantum many-body systems have a ground state degeneracy that is stable to long-range (e.g., power-law) perturbations, in the sense that any ground state energy splitting induced ...
0) a better trial state than the ferromagnetic state | ⇑ for large enough system size L. ...
arXiv:2107.11396v2
fatcat:67yis4hjz5bmdj5npwjjoghluy
Inosine as a Tool to Understand and Treat Central Nervous System Disorders: A Neglected Actor?
2021
Frontiers in Neuroscience
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and pathological processes in the central nervous system (CNS). ...
Also, inosine was identified as a natural trigger of adenosine receptors. ...
In parallel, identifying the mechanisms involved in the inosine effects in epilepsy is critical and can be performed using genetic, pharmacological, and in vitro approaches. ...
doi:10.3389/fnins.2021.703783
pmid:34504414
pmcid:PMC8421806
fatcat:ieusk2ku6jadnclsue4g67abva
Impact of Pre-Analytical Variables on Cancer Targeted Gene Sequencing Efficiency
2015
PLoS ONE
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Herein, we evaluated the effect of pre-sequencing parameters to guide proper sample selection for targeted gene sequencing. ...
Data from 113 FFPE lung tumor specimens were collected, and targeted gene sequencing was performed. ...
Variant calling was performed using the Genome Analysis Tool Kit (GATK) Unified Genotyper. ...
doi:10.1371/journal.pone.0143092
pmid:26605948
pmcid:PMC4659597
fatcat:7yzaf65htbfjvo4xqpv25bphfa
Recent Paradigm Shifts in Molecular Cardiac Imaging – Establishing Precision Cardiology through Novel 18F-labeled PET Radiotracers
2019
Trends in cardiovascular medicine
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Due to physical and chemical key properties, these imaging agents allow for more flexibility of imaging protocols and a better employment in the clinic. ...
more thorough evaluation, mainly due to superior characteristics associated with the latter imaging modality. ...
Their long half-life of 110 min allow for a.) the use of dispatch systems (for delivery from central cyclotron facilities), b.) the injection of a lower amount of radioactivtiy (due to a higher positron ...
doi:10.1016/j.tcm.2019.02.007
pmid:30824163
fatcat:3fraundkeneard5m2swgrdic2y
Cyclotron resonant scattering feature simulations
2017
Astronomy and Astrophysics
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to gain information about the underlying physics in these systems. ...
We develop a new simulation code to generate synthetic cyclotron lines for complex scenarios, allowing for unprecedented physical interpretation of the observed data. ...
We thank the International Space Science Institute in Bern for inspiring team meetings. The fruitful discussions within the MAGNET collaboration also had a very positive impact on this work. ...
doi:10.1051/0004-6361/201630250
fatcat:gkavolbtdvdajet62w2ibpwipe
Deconstructing Local Adaptation Plans for Action (LAPAs) Analysis of Nepal and Pakistan LAPA initiatives Deconstructing Local Adaptation Plans for Action (LAPAs) Analysis of Nepal and Pakistan LAPA initiatives
unpublished
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While each frame is a powerful tool of analysis in its own right, this paper focuses on the structural frame for comparing the two country LAPAs. ...
(prioritization of adaptation options), LAPA implementation and annual assessment Tool kit for LAPA development 15 participatory tools deployed Assessment of risks, design of strategy and methods and ...
fatcat:k5yi2ggworhfpizdo5tk5y2cwu
Thyroglobulin fluctuations in patients with iodine-refractory differentiated thyroid carcinoma on lenvatinib treatment – initial experience
2016
Scientific Reports
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Tumor restaging was performed every 2-3 months including contrastenhanced computed tomography (CT, RECIST 1.1). Serum Tg was measured and compared to imaging findings. ...
Initiation of lenvatinib in iodine-refractory DTC patients is associated with a significant reduction in serum Tg levels as a marker of treatment response. ...
Additionally, we express our gratitude to Johanna Vogt for her assistance in data analysis. ...
doi:10.1038/srep28081
pmid:27306607
pmcid:PMC4910099
fatcat:kvvnil4f2zdrbduwzkzgtg3qpm
Fitting strategies of accretion column models and application to the broadband spectrum of Cen X-3
[article]
2021
arXiv
pre-print
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We demonstrate this approach as well a study of possible parameter degeneracies with a comprehensive Markov-chain Monte Carlo analysis of the complete parameter space for a combined NuSTAR and Swift/XRT ...
While the behavior of these models is well understood and they allow for a comparison of different sources and studying source behavior, the extent to which the underlying physics can be derived from the ...
This research also has made use of a collection of ISIS functions (ISISscripts) provided by ECAP/Remeis observatory and MIT (http://www.sternwarte.unierlangen.de/isis/). ...
arXiv:2109.14565v1
fatcat:sqtyxob3mvf5bako2jg3ufxgbm
A Novel CXCL10-Based GPI-Anchored Fusion Protein as Adjuvant in NK-Based Tumor Therapy
2013
PLoS ONE
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Methodology/Principal Findings: A fusion protein comprising a CXCL10 chemokine head (CXCL10-mucin-GPI) was used for proof of concept for this approach and expressed constitutively in Chinese Hamster Ovary ...
Cellular therapy is a promising therapeutic strategy for malignant diseases. The efficacy of this therapy can be limited by poor infiltration of the tumor by immune effector cells. ...
Mack for providing the MP71 and pEF vectors, respectively, as well as Frank Lehmann for providing the murine T cells.
Author Contributions ...
doi:10.1371/journal.pone.0072749
pmid:24023642
pmcid:PMC3758322
fatcat:khks6dr5hbhujogwv4n4od6poa
Ga and Ce ion-doped phosphate glass fibres with antibacterial properties and their composite for wound healing applications
2019
Journal of materials chemistry. B
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Soluble Ga/Ce-doped phosphate glass fibres exhibiting controlled release of ions were developed and characterised for wound healing applications. ...
Moreover, solid state NMR analysis would be a powerful tool to evaluate the character of the bonding in PGF. ...
A glass fibre mesh was also subsequently developed as a degradable dressing for wound healing applications and properties such as degradation and water uptake were also evaluated. ...
doi:10.1039/c9tb00820a
pmid:31624824
fatcat:mjefenpw6rcefflh3yuvkyic2a
Prevalence and characteristics of new-onset pain in COVID-19 survivors, a controlled study
2021
European Journal of Pain
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No statistically significant differences were found for mean new-onset pain intensity and interference with daily activities between both groups. ...
COVID-19 was associated with a significantly higher prevalence of de novo CP, chronic daily headache, and new-onset pain in general, which was associated with persistent anosmia. ...
All interviews were performed by a line phone or by a video-call in some instances. No financial compensation was provided for study participation. ...
doi:10.1002/ejp.1755
pmid:33619793
pmcid:PMC8013219
fatcat:ylrmdvjb45f4hnlzu772umhmkq
The Mycobacterium tuberculosis Complex-Restricted Gene cfp32 Encodes an Expressed Protein That Is Detectable in Tuberculosis Patients and Is Positively Correlated with Pulmonary Interleukin-10
2003
Infection and Immunity
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Overall, CFP32 is an attractive target for drug and vaccine design as well as new diagnostic strategies. Downloaded from FIG. 8. ...
active TB case patients, along with the sera of 11 healthy household contacts (seven PPD skin test negative and four PPD skin test positive), were used in an ELISA to identify human humoral specificity for ...
Johnson for suggestions, support, and encouragement. ...
doi:10.1128/iai.71.12.6871-6883.2003
pmid:14638775
pmcid:PMC308900
fatcat:g3sehgnezbaejjprwgyfougr54
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