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SArF Map: Visualizing Software Architecture from Feature and Layer Viewpoints [article]

Kenichi Kobayashi, Manabu Kamimura, Keisuke Yano, Koki Kato, Akihiko Matsuo
2013 arXiv   pre-print
To facilitate understanding the architecture of a software system, we developed SArF Map technique that visualizes software architecture from feature and layer viewpoints using a city metaphor. SArF Map visualizes implicit software features using our previous study, SArF dependency-based software clustering algorithm. Since features are high-level abstraction units of software, a generated map can be directly used for high-level decision making such as reuse and also for communications between
more » ... evelopers and non-developer stakeholders. In SArF Map, each feature is visualized as a city block, and classes in the feature are laid out as buildings reflecting their software layer. Relevance between features is represented as streets. Dependency links are visualized lucidly. Through open source and industrial case studies, we show that the architecture of the target systems can be easily overviewed and that the quality of their packaging designs can be quickly assessed.
arXiv:1306.0958v1 fatcat:lartlzdvanadpnjttn5omvebde

AN ANALYTICAL STUDY OF THE GROWTH CURVE

KOKI ABE, KUNIO YANO
1954 The Kurume Medical Journal  
Deaf height KOKI ABE AND KUNIO YANG 14 for the mormal, less prominently at 11 and 13 for the blind, and similarly at 13, 15 and 17 for the deaf.  ...  M.D. 67 KOKI ABE AND KUNIO YANG The units used in Figs 1-6 (of which 4, 5 and 6 are not presented here) for height are y ; cm y'; cm/age z ; 10-3/age y" ; cm/age2 Those for weight are  ... 
doi:10.2739/kurumemedj.1.67 fatcat:jdel7x5fjzf4fpabcflmcb4z7u

Spontaneous regression of nonfunctioning pituitary macroadenoma: A case report

Koki Kameno, Shigetoshi Yano, Naoki Shinojima, Jun-ichi Kuratsu
2016 Interdisciplinary Neurosurgery  
A case involving a 13-year-old girl with nonfunctioning pituitary macroadenoma is discussed. The patient visited the hospital for checkup after experiencing a head injury secondary to syncope. A computed tomography (CT) scan revealed a pituitary mass with mildly higher density. Magnetic resonance imaging (MRI) with contrast enhancement showed that the mass contained a hyperintense area and it elevated the optic chiasm. The patient had blurred vision in her right eye. No endocrinological
more » ... ities were found. When the patient was admitted for surgical removal of the mass 1 month later, her visual acuity had improved. A repeat MRI showed that the size of the pituitary mass had dramatically reduced. During the following 2 years, the mass showed further reduction in size and did not re-grow. Since symptoms of pituitary apoplexy were not observed, we believe that asymptomatic apoplexy occurring at the time of the first visit may have caused regression of the tumor.
doi:10.1016/j.inat.2016.06.003 fatcat:kzipfpjnvbdmzlskdbswke7pqq

Development of microsatellite markers for a giant water bug, Appasus japonicus, distributed in East Asia [article]

Tomoya Suzuki, Akira S. Hirao, Masaki Takenaka, Koki Yano, Koji Tojo
2020 bioRxiv   pre-print
PCR amplification with fluorescent dye-labeled 6 primers was performed using a protocol described by Shimizu and Yano (2011).  ...  This study was supported by JSPS KAKENHI H., Katano, I., Sakata, Y., Souma, R., Kosuge, T., Nagano, M., Ikeda, K., Yano, K., 12 and Tojo, K. (2017).  ... 
doi:10.1101/2020.05.25.115501 fatcat:adbhrdyj3jbijcnduy5ksylqs4

Understanding the Role of Temperature and Drain Current Stress in InSnZnO TFTs with Various Active Layer Thicknesses

Dapeng Wang, Mamoru Furuta, Shigekazu Tomai, Koki Yano
2020 Nanomaterials  
Thin-film transistor (TFT) devices composed of metal oxide semiconductors have attracted tremendous research attention globally in recent years. Owing to their ability to offer mobility, metal oxide semiconductor materials can enable high-performance TFTs for next-generation integrated display devices. Nevertheless, further breakthroughs of metal oxide TFTs are mainly obstructed by their long-term variability, the reason for which is not yet fully understood. Herein, TFTs based on InSnZnO
more » ... with various thicknesses (TITZO) were prepared and their long-term stabilities under test temperatures and drain current stress were investigated. The results indicate that ITZO TFTs exhibit outstanding electrical properties regardless of the TITZO, including a high saturated mobility of over 35 cm2V−1s−1 and sharp subthreshold swing. Note that the transfer and output characteristic curves of the device with a thick TITZO of 100 nm express an abnormal current surge when high gate and drain voltages are exerted, which is attributed to the floating body effect, caused when the imposed electric field induces impact ionization near the drain side. More interestingly, these drain current stress results further suggest that the abnormal shift behavior of the electrical properties of the ITZO TFTs with a TITZO of greater than 75 nm is observed to deteriorate gradually with increasing temperature and drain current bias. This study addresses that such a degradation effect should be restrained for the operation of high-mobility devices.
doi:10.3390/nano10040617 pmid:32230775 fatcat:d5pqzea7wff47l6qam2naunnlu

Development of microsatellite markers for a giant water bug, Appasus japonicus, distributed in East Asia

Tomoya Suzuki, Akira S. Hirao, Masaki Takenaka, Koki Yano, Koji Tojo
2021 Genes & Genetic Systems  
., 2018; Sekiné and Tojo, 2019; Yano et al., 2019) .  ...  PCR amplification with fluorescent dye-labeled primers was performed using a protocol described by Shimizu and Yano (2011) .  ... 
doi:10.1266/ggs.20-00033 pmid:33487614 fatcat:h2dtqdyz7jfsziys2kswbctrqy

Cryptococcus neoformans Meningoencephalitis with Multiple Cerebral Infarctions in a non-HIV Patient

Koki KIKUCHI, Ryosuke OSAWA, Ryosuke YAMAMURO, Yudai YANO, Tomohisa WATARI, Yoshihito OTSUKA, Naoto HOSOKAWA
2021 Kansenshogaku zasshi  
doi:10.11150/kansenshogakuzasshi.95.335 fatcat:pmlvzrfmknb3jcyzpzys3svszi

Final storage of radioactive cesium by pollucite hydrothermal synthesis

Yoshinobu Yokomori, Kazuhito Asazuki, Natsumi Kamiya, Yudai Yano, Koki Akamatsu, Tetsuya Toda, Atsushi Aruga, Yoshiaki Kaneo, Seiko Matsuoka, Koji Nishi, Satoshi Matsumoto
2014 Scientific Reports  
The Fukushima nuclear accident has highlighted the importance of finding a better final storage method for radioactive cesium species. Cs is highly soluble in water, and can easily exchange with other alkali ions in zeolites or clays to form stable complexes. However, Cs 1 is released from Cs 1 complexes into water when surrounded by an excess of water. Pollucite may be the best final storage option for Cs 1 , but its typical synthesis requires heating to about 12006C in air. Here, we show that
more » ... the hydrothermal synthesis of pollucite can be completed at 3006C in three hours from any zeolite or clay. Furthermore, our procedure does not require ion exchange before synthesis. Radioactive Cs is usually found in complexes with clays. At that time, this method only requires calcium hydroxide, water, and three hours of hydrothermal synthesis, so the process is both inexpensive and practical for large-scale application. Pollucite is an analog of analcime zeolite, and contains a channel system 2.8 Å in diameter, which is formed by 6-oxygen rings. As the diameter of Cs 1 is 3.34 Å and each Cs 1 exists independently within a separate portion of the channel, Cs 1 cannot exit the pollucite framework without breaking it.
doi:10.1038/srep04195 pmid:24569302 pmcid:PMC3935194 fatcat:liat5mbaujh3xdyqsubpolyx5m

Follicular lymphoma Grade 1 of the minor duodenal papilla successfully diagnosed by endoscopic papillectomy

Takashi Abe, Kosuke Kodama, Takayuki Nagai, Koki Yamanaka, Masato Hanzawa, Takafumi Yano, Kazunari Murakami
2020 Endoscopy  
doi:10.1055/a-1173-8418 pmid:32483776 fatcat:n3bfxafgijbizk4rrw4572fbwu

Fluorescence Enhancement Effect of TiO2 Nanoparticles and Application for Photodynamic Diagnosis

Koki Kanehira, Yukiko Yano, Hisashi Hasumi, Hideo Fukuhara, Keiji Inoue, Kazuhiro Hanazaki, Masahiro Yao
2019 International Journal of Molecular Sciences  
Photodynamic diagnosis (PDD) can improve diagnostic accuracy by using PDD agents such as 5-aminolevulinic acid (ALA). However, the weakness and photobleaching of fluorescence of PDD agents may lead to insufficient fluorescence visibility for the detection of cancer during resection operations. We focused on the "fluorescence enhancement effect" resulting from the addition of polyethylene glycol-modified titanium dioxide nanoparticles (TiO2-PEG NPs) to address these problems. The results showed
more » ... hat the combined administration of TiO2-PEG NPs and ALA could enhance and prolong fluorescence in bladder cancer cells, similar to in the mixture alone. It was suggested that the fluorescence enhancement was related to the accumulation of TiO2-PEG NPs in cells via endocytosis, causing the light scattering and enhancement of fluorescence. This fluorescence enhancement effect could be applicable for PDD.
doi:10.3390/ijms20153698 fatcat:mi5ugegxnvbdzichdxopsjzymq

Impact of Photo-Excitation on Leakage Current and Negative Bias Instability in InSnZnO Thickness-Varied Thin-Film Transistors

Dapeng Wang, Mamoru Furuta, Shigekazu Tomai, Koki Yano
2020 Nanomaterials  
InSnZnO thin-film transistors (ITZO TFTs), having high carrier mobility, guarantee the benefits of potential applications in the next generation of super-high-definition flat-panel displays. However, the impact of photo-excitation on the leakage current and negative bias stress (NBIS) of ITZO TFTs must be further explored. In this study, the ITZO thickness (TITZO) is designed to tailor the initial performance of devices, especially for the 100 nm TITZO TFT, producing excellent electrical
more » ... ies of 44.26 cm2V−1s−1 mobility, 92 mV/dec. subthreshold swing (SS), 0.04 V hysteresis, and 3.93 × 1010 ON/OFF ratio, which are superior to those of the reported ITZO TFTs. In addition, incident light coupled with tunable photon energy is introduced to monitor the leakage current of various TITZO devices. The OFF-current results demonstrate that under the identical photon energy, many more electrons are photo-excited for the thicker TITZO TFTs. NBIS-induced Vth shift and SS deterioration in all TFTs are traced and analyzed in real time. As the TITZO thickens to near Debye length, the degree of degradation is exacerbated. When the thickness further increases, the notorious instability caused by NBIS is effectively suppressed. This study provides an important research basis for the application of ITZO-based TFTs in future displays.
doi:10.3390/nano10091782 pmid:32916832 fatcat:wtkm4litczakjoc4ajsjtcxp4i

GH-16 type β-1,3-glucanase from Lysobacter sp. MK9-1 enhances antifungal activity of GH-19 type chitinase, and its glucan-binding domain binds to fungal cell-wall

Yuitsu Otsuka, Koki Sato, Shigekazu Yano, Haruki Kanno, Wasana Suyotha, Hiroyuki Konno, Koki Makabe, Toki Taira
2022 Journal of Applied Glycoscience  
The GH-16 type β-1,3-glucanase (BgluC16MK) gene of Lysobacter sp. MK9-1 was cloned to study its antifungal activities. BgluC16MK displays amino acid sequence similarity with GluC from L. enzymogenes strain N4-7. BgluC16MK includes a signal sequence, a catalytic domain and carbohydrate-binding module family 6-type β-glucan binding domain (B-GBD). The expression of the BgluC16MK gene in Escherichia coli without the signal sequence resulted in antifungal activity at a dose of 0.6-0.8 nmol/disk.
more » ... ever, BgluC16MK displayed antifungal activity at a dose of 0.025 nmol/disk in combination with Chi19MK. Substrate-specific assay revealed that purified BgluC16MK hydrolyzed insoluble curdlan more readily than the soluble substrate. Furthermore, to explore the binding selectivity of B-GBD of BgluC16MK, we constructed a fusion protein (B-GBD-GFP) using the B-GBD and green fluorescent protein. The activity of the fusion protein against various substrates indicates that B-GBD was selective for glucans with β-1,3-linkages. An additional study demonstrated the binding ability of B-GBD-GFP to the cell-wall of living fungi, such as T. reesei and Aspergillus oryzae. These findings suggest that BgluC16MK can be utilized to generate antifungal enzyme preparations and that the fusion protein B-GBD-GFP can be used to identify the fungal cell surface structure using β-glucans.
doi:10.5458/jag.jag.jag-2022_0002 fatcat:h23bqwpit5dxzguqy2ype5f22a

Endoscopic band ligation and over-the-scope clip placement for refractory bleeding of Dieulafoy ulcer in the jejunum

Takafumi Yano, Takayuki Nagai, Koki Yamanaka, Masato Hanzawa, Kosuke Kodama, Takashi Abe, Kazunari Murakami
2020 Endoscopy  
The authors Takafumi Yano 1 , Takayuki Nagai 1 , Koki  ... 
doi:10.1055/a-1195-1795 pmid:32590857 fatcat:ti4lpmnxdzarjkaolu2gcshjc4

Isotopically enriched ammonium shows high nitrogen transformation in the pile top zone of dairy manure compost

Koki Maeda, Sakae Toyoda, Midori Yano, Shohei Hattori, Makoto Fukasawa, Keiichi Nakajima, Naohiro Yoshida
2016 Biogeosciences  
Yano and M. Fukasawa carried out the experiments. K. Maeda, S. Toyoda and S. Hattori analyzed the results. K. Maeda, K. Nakajima and N. Yoshida wrote the paper.  ... 
doi:10.5194/bg-13-1341-2016 fatcat:54qdzhvhbrggzbgbr45us4s76m

Detection of an endangered aquatic heteropteran using environmental DNA in a wetland ecosystem

Hideyuki Doi, Izumi Katano, Yusuke Sakata, Rio Souma, Toshihiro Kosuge, Mariko Nagano, Kousuke Ikeda, Koki Yano, Koji Tojo
2017 Royal Society Open Science  
doi:10.1098/rsos.170568 pmid:28791177 pmcid:PMC5541572 fatcat:4kr4wntu5rh53hbhphm6gwp7se
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