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Knee Cartilage Segmentation Using Diffusion-Weighted MRI [article]

Alejandra Duarte, Chaitra V. Hegde, Aakash Kaku, Sreyas Mohan, José G. Raya
2019 arXiv   pre-print
Code is available at https://github.com/aakashrkaku/knee-cartilage-segmentation  ...  In conclusion, cartilage segmentation on DW-MRI images with modified U-Nets achieves accuracy that outperforms the human segmenter.  ...  Cem Deniz for useful discussions, and guidance.  ... 
arXiv:1912.01838v1 fatcat:dlxmvvsx5rfzjaqy3dg76pojlm

Review of Quantitative Knee Articular Cartilage MR Imaging

Mai Banjar, Saya Horiuchi, David N. Gedeon, Hiroshi Yoshioka
2021 Magnetic Resonance in Medical Sciences  
MRI is widely used as a non-invasive imaging tool for OA of the knee.  ...  MRI of cartilage (dGEMRIC), sodium MRI, diffusion-weighted imaging (DWI)/ diffusion tensor imaging (DTI), ultrashort TE (uTE), and glycosaminoglycan specific chemical exchange saturation transfer (gagCEST  ...  , apparent diffusion coefficient; dGEMRIC, delayed gadolinium-enhanced MRI of cartilage; DTI, diffusion tensor imaging; DWI, diffusion- weighted imaging; FCD, fixed charged density; GAG, glycosaminoglycan  ... 
doi:10.2463/mrms.rev.2021-0052 pmid:34471014 fatcat:fmsnxdsy7zc3pduwd6vacguj3i

403 ASSESSMENT OF THE RADIAL DISTRIBUTION OF GLYCOSAMINOGLYCANS IN ARTHRITIC HIPS USING DELAYED GADOLINIUM ENHANCED MRI OF CARTILAGE

S. Sur, I. Kress, C.T. Mamisch, Y-J. Kim
2008 Osteoarthritis and Cartilage  
Table 1: Inter-and intra-reader agreement for individual synovitis sites scores Feature Intra-reader 1 weighted-kappa (95% CI) Intra-reader 2 weighted-kappa (95% CI) Inter-readers weighted-kappa (95% CI  ...  Purpose: Radiographic minimum Joint Space Width (minJSW) is the primary structural endpoint used as an indirect measure of articular  ...  Using a new dedicated foot and ankle coil, the purpose of the present study was to assess quantitative values for T2 and T2* relaxation as well as Diffusion-Weighted-Imaging (DWI) in healthy volunteers  ... 
doi:10.1016/s1063-4584(08)60444-6 fatcat:e7lhp7b5b5dyjpwohmu2yr6loq

Non-invasive MRI assessment of the articular cartilage in clinical studies and experimental settings

Yi-Xiang J Wang
2010 World Journal of Radiology  
MRI detected cartilage loss has been shown to be more sensitive than radiographs detecting joint space narrowing.  ...  Chondral injuries are also common in the knee joint, and many patients benefit from cartilage repair.  ...  The MR sequences that have been most commonly used for cartilage assessment are FS T1-weighted spoiled GE sequences.  ... 
doi:10.4329/wjr.v2.i1.44 pmid:21160740 pmcid:PMC2999310 fatcat:fdu6nirsofca3cypmufuwdtriq

Pre-contrast T1 and cartilage thickness as confounding factors in dGEMRIC when evaluating human cartilage adaptation to physical activity

Carl Johan Tiderius, Zana K. Hawezi, Lars E. Olsson, Leif E. Dahlberg
2019 BMC Medical Imaging  
The dGEMRIC (delayed Gadolinium-Enhanced MRI of Cartilage) technique has been used in numerous studies for quantitative in vivo evaluation of the relative glycosaminoglycan (GAG) content in cartilage.  ...  The purpose of this study was to determine the influence of pre-contrast T1 and cartilage thickness when assessing knee joint cartilage quality with dGEMRIC.  ...  The femoral knee cartilage was divided into two main segments: weight-bearing (WB) and non-weight-bearing (NWB).  ... 
doi:10.1186/s12880-019-0399-0 pmid:31892314 pmcid:PMC6938637 fatcat:5uwsgkh4bzcovehemm3ywhc5uu

Clinically applied CT arthrography to measure the sulphated glycosaminoglycan content of cartilage

M. Siebelt, J. van Tiel, J.H. Waarsing, T.M. Piscaer, M. van Straten, R. Booij, M.L. Dijkshoorn, G.J. Kleinrensink, J.A.N. Verhaar, G.P. Krestin, H. Weinans, E.H.G. Oei
2011 Osteoarthritis and Cartilage  
s u m m a r y Objective: Similar to delayed gadolinium enhanced MRI of cartilage, it might be possible to image cartilage quality using CT arthrography (CTa).  ...  Additionally, residual values from the linear fit between ncCT and mCT were used as a covariate measure to identify the influence of structural composition of cartilage ECM on contrast diffusion into cartilage  ...  We used a 20% solution of ioxaglate, which resulted in the best cartilage segmentation at the air/cartilage and bone/ cartilage interfaces.  ... 
doi:10.1016/j.joca.2011.07.006 pmid:21820067 fatcat:7vboum3vxzhk3dolclnmdgp6ay

Advanced Imaging in Osteoarthritis

Qi Li, Keiko Amano, Thomas M. Link, C. Benjamin Ma
2016 Sports Health A Multidisciplinary Approach  
The diffusion of water is measured through macromolecules. There are 2 major types of diffusion imaging: diffusion-weighted imaging and diffusion tensor imaging.  ...  These use a diffusion quotient or apparent diffusion coefficient as parameters for the degree of water diffusion and fractional anisotropy, which indicates the water diffusion in various orientations.  ... 
doi:10.1177/1941738116663922 pmid:27510507 pmcid:PMC5010138 fatcat:th2pcdptdrebnm22tcbxwfqva4

401 A NOVEL SEMIQUANTITATIVE WHOLE-KNEE SCORING SYSTEM FOR THE ASSESSMENT OF SYNOVITIS IN KNEE OA ON CONTRAST-ENHANCED MRI – THE MOST STUDY

A. Guermazi, F.W. Roemer, M.D. Crema, J. Niu, M.D. Marra, J.A. Lynch, G.Y. El-Khoury, L.B. Hughes, M.C. Nevitt, D.T. Felson
2008 Osteoarthritis and Cartilage  
Seven experienced readers segmented the medial tibial (MT), lateral tibial (LT), medial (weight-bearing) femoral (cMF) and lateral femoral cartilage (cLF), with blinding to the order of acquisition.  ...  Cartilage volume (VC) and mean cartilage thickness over the entire subchondral bone area (ThCtAB) were computed using proprietary software.  ...  For these reasons, we suggest that assessment of synovitis at multiple sites on CE MRI is a superior measure of localized as well as diffuse synovitis of the knee joint.  ... 
doi:10.1016/s1063-4584(08)60442-2 fatcat:db7dzrd5avacdiwsqvvableulq

Tractography of Porcine Meniscus Microstructure Using High-Resolution Diffusion Magnetic Resonance Imaging

Jikai Shen, Qi Zhao, Yi Qi, Gary Cofer, G. Allan Johnson, Nian Wang
2022 Frontiers in Endocrinology  
To noninvasively evaluate the three-dimensional collagen fiber architecture of porcine meniscus using diffusion MRI, meniscal specimens were scanned using a 3D diffusion-weighted spin-echo pulse sequence  ...  The tractography based on diffusion MRI may provide a complementary method to study the integrity of meniscus and nondestructively visualize the 3D collagen fiber architecture.  ...  The T2*weighted image derived from MGRE scans were used for segmentation purpose only.  ... 
doi:10.3389/fendo.2022.876784 fatcat:kyy2rohqbra2bfy2gs4ygifowe

Quantitative T1ρ, T2 and T2* mapping of articular cartilage changes in a rat model of osteoarthritis using in vivo high-resolution magnetic resonance imaging

G. Mohan, G. Melkus, K. Subburaj, S. Magnitsky, A. Dang, N.E. Lane, S. Majumdar
2014 Osteoarthritis and Cartilage  
Conclusions: Our results suggest that diffusion weighted imaging with a modified 3D double echo steady state (DESS) sequence acquired with high diffusion gradient is a promising MRI technique for the reliable  ...  The purpose of this study was to compare DESS with contrast-enhanced MRI for knee synovitis assessment.  ...  Conclusions: Our results suggest that diffusion weighted imaging with a modified 3D double echo steady state (DESS) sequence acquired with high diffusion gradient is a promising MRI technique for the reliable  ... 
doi:10.1016/j.joca.2014.02.482 fatcat:rjwtg3th2fcybkvtjr3kwww2yi

Osteoarthritis year 2012 in review: imaging

Frank W. Roemer, Ali Guermazi
2012 Osteoarthritis and Cartilage  
Methods: To extract relevant studies, an extensive PubMed database search was performed using the query terms "osteoarthritis" in combination with "MRI", "imaging", "radiography", "ultrasound", "computed  ...  Most imaging research is still concentrated on the knee although interest in other sites, especially the hand, has increased since the last OARSI meeting.  ...  It has to be kept in mind that using segmentation approaches for ill-defined lesions is more challenging than segmentation of clearly delineated structures such as cartilage on high-resolution 3D sequences  ... 
doi:10.1016/j.joca.2012.07.008 pmid:22824160 fatcat:susazgj7hnfzrjmkrexsnj5aqu

Clinical and Translational Potential of MRI Evaluation in Knee Osteoarthritis

Daichi Hayashi, Ali Guermazi, C. Kent Kwoh
2013 Current Rheumatology Reports  
MRI offers semiquantitative, quantitative and compositional evaluation of knee OA, and enables visualization of tissues that are not seen by radiography, including but not limited to cartilage, meniscus  ...  Magnetic resonance imaging (MRI) has become an increasingly important imaging technique in osteoarthritis (OA) research, and is widely used in the ongoing endeavor to understand the pathogenesis of OA  ...  Raya et al. found that in-vivo diffusion tensor imaging based on a 7 T MR system was better able than T2 mapping to distinguish OA knees from non-OA knees [29] .  ... 
doi:10.1007/s11926-013-0391-6 pmid:24318386 pmcid:PMC4555353 fatcat:iyrw4l4fkjhwjanzn4m465dm5u

405 THE RELEVANCE OF METABOLIC CRUCIATE LIGAMENT CHANGES TO KNEE OSTEOARTHRITIS

F.R. Nelson, H. Makker
2011 Osteoarthritis and Cartilage  
Here, precision was evaluated using double measurements of 20 cadaveric knees.  ...  In our review of MRI for knee osteoarthritis (OA) we noted increased bone signal and cysts in T2 weighted images at insertion sites for both the both the anterior and posterior cruciate ligaments.  ...  Here, precision was evaluated using double measurements of 20 cadaveric knees.  ... 
doi:10.1016/s1063-4584(11)60432-9 fatcat:anvem24yhjflnatqmweaendya4

Magnetic Resonance Imaging of Articular Cartilage

Shaafiya Ashraf, Adnan Zahoor
2016 JBJS Reviews  
» Magnetic resonance imaging (MRI) has emerged as a noninvasive tool for direct 2-dimensional (2D) and 3-dimensional (3D) assessment of the articular cartilage in both clinical and research settings.  ...  changes prior to morphological changes). » MRI is evolving as a complete answer to our cartilage-imaging requirements of lesion description, treatment planning, and outcome measurement as well as in various  ...  Attempts were made to use diffusion-weighted imaging (DWI) to assess increased apparent diffusion coefficient (ADC) in degeneration.  ... 
doi:10.2106/jbjs.rvw.15.00093 pmid:27603269 fatcat:eqps35q2vzgzddjiszjjwch7k4

406 PRECISION OF QCT OF THE KNEE

T. Lowitz, P. Zerfaß, O. Museyko, L. Laouisset, J.-D. Laredo, V.D. Bousson, W.A. Kalender, K. Engelke
2011 Osteoarthritis and Cartilage  
Here, precision was evaluated using double measurements of 20 cadaveric knees.  ...  In our review of MRI for knee osteoarthritis (OA) we noted increased bone signal and cysts in T2 weighted images at insertion sites for both the both the anterior and posterior cruciate ligaments.  ...  Here, precision was evaluated using double measurements of 20 cadaveric knees.  ... 
doi:10.1016/s1063-4584(11)60433-0 fatcat:eu2c422ppvdetokok3fkobc3ue
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