A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2008; you can also visit the original URL.
The file type is
Greenstone and DSpace are widely used software systems for digital libraries, and prospective users sometimes wonder which one to adopt. In fact, the aims of the two are very different, although their domains of application do overlap. This article describes the two systems and identifies their similarities and differences. We also present StoneD [note 1] a bridge between the production versions of Greenstone and DSpace that allows users of either system to easily migrate to the other, ordoi:10.1045/september2005-witten fatcat:uyqkf3wkwbc5dc6c3jtyxo53wq
more »... ue with a combination of both. This bridge eliminates the risk of finding oneself locked in to an inappropriate choice of system. We also discuss other possible opportunities for combining the advantages of the two, to the benefit of the user communities of both systems.
., 2013; Huang et al., 2020; Liu et al., 2019; Szabo de Edelenyi et al., 2020) . ... Details of Adachi et al. (2019) and Huang et al. (2020) are described above. ...doi:10.1101/2022.02.24.22271464 fatcat:3tkdewaowjfofixtmg2nhrmfva
Chronic psychological distress has been associated with increased risk of cardiovascular disease (CVD). However, mechanistic evidence explaining the observed associations remains limited and, with data are particularly sparse among women. This study examined if a metabolite profile linked with distress would be associated with increased risk of CVD. Methods: A plasma metabolite-based distress score (MDS) of twenty metabolites was derived in a cross-sectional, 1:1 matched case-control datasetdoi:10.1101/2022.02.26.22271549 fatcat:gflyeexqd5a3jgujakidrjijpq
more »... 558 women) in the Nurses' Health Study (NHS). We then calculated this score in two other cohorts, the Women's Health Initiative Observational Cohort (WHI_OS) and the Prevencion con Dieta Mediterranea (PREDIMED) trial, and tested association with risk of developing adjudicated measures of CVD in each cohort. We considered incident coronary heart disease (CHD) in the WHI_OS dataset which included 944 postmenopausal women (472 CHD cases; mean time to event of 5.8 years), and incident CVD (including stroke, myocardial infarction, CVD death) in the PREDIMED dataset which included 980 men and women (224 CVD cases, mean time to event of 3.1 years). Results: In the WHI_OS, a 1 SD increase in the plasma MDS was associated with a 14% increased risk of incident CHD (odds ratio [OR]=1.14, 95% CI: [1.03, 1.26]), adjusting for known CVD risk factors excluding total and HDL cholesterol. This association was attenuated after including total and HDL cholesterol (OR=1.09; 95% CI: [0.98, 1.21]). Of the component metabolites in the MDS, tryptophan and threonine were inversely associated with incident CHD risk. In PREDIMED, each one SD increase in the MDS was associated with a 17% increased incident CVD risk (OR=1.17, 95% CI: [1.00, 1.38]), after adjusting for risk factors including total and HDL cholesterol. Similar associations were observed in men and women. Four individual metabolites in the MDS were associated with incident CVD risk in fully adjusted models in PREDIMED. Biliverdin and C36:5 PC plasmalogen had inverse associations, whereas C16:0 ceramide and C18:0 LPE each had positive associations with CVD risk. Conclusions: Our study sheds light on the key molecular alterations that characterize chronic distress and are predictive of subsequent CVD risk in men and women. These findings provide additional evidence for the role of distress in CVD development.
Study was supported by grant 1R01AI88116 from the National Institute of Allergy and Infectious Disease at the National Institutes of Health (principal investigator: Dr Kahn; coinvestigators: Drs Beck, Huang ...doi:10.1001/jamapediatrics.2016.0269 pmid:27182793 pmcid:PMC5503118 fatcat:nm3twsnpuzgzvbcikhem44nywy
The CH 2 Cl 2 fractions were subsequently catalytically hydrogenated (PtO 2 /H 2 ) and analyzed on GC using androstane as an internal standard. ... Isorenieratene was not detected at 11±12 cm, but had a concentration of 0.1 m/gdw at 24±25 cm. h Not detected. i n.d.=Not determined. ern Black Sea margin. ...doi:10.1016/s0146-6380(00)00090-5 fatcat:wkofjqc3wzbg7ggrzrhvrjwega
PBMC were harvested by using 8 to 10 h of leukapheresis beginning on day 0. ... Beginning on day -4 until day -1, recipients received 50 μg/kg of a recombinant CD3 immunotoxin twice daily, 8 h apart. ...pmid:26473348 pmcid:PMC4617335 fatcat:kmdacurz4bhd5liwlmmglhodly
ment. CPP was significantly associated with a higher ACR in fully adjusted models (β (95% CI) = 0.14 (0.03, 0.24) ln mg/g per SD). Higher CFPWV was associated with lower eGFR and higher ACR in unadjusted analyses but not after adjustment. Conclusion: Greater aortic stiffness may be associated with modestly higher levels of albuminuria in the elderly. The association between aortic stiffness and lower eGFR may be confounded by age and CVD risk factors. Abstract Background/Aims: The causes ofdoi:10.1159/000431332 pmid:26067356 pmcid:PMC4514536 fatcat:ixxphzwai5aqvbi4racxgfufxq
more »... nic kidney disease (CKD) in older people are not well understood. Aortic stiffness increases with age and results in the transmission of increased pulsatility into the kidney microvasculature, potentially contributing to CKD in older populations. Methods: We utilized data from the Age, Gene/Environment, Susceptibility-Reykjavik Study, a community-based prospective cohort study of cardiovascular disease (CVD) in Iceland. The relationship of carotid pulse pressure (CPP) and carotid-femoral pulse wave velocity (CFPWV) with estimated glomerular filtration rate (eGFR) based on creatinine and cystatin C and urine albumin-creatinine ratio (ACR) was assessed using linear regression, adjusting for demographics and CVD risk factors. Results: 940 participants (mean (SD) age 75.8 (4.7) years, mean (SD) CFPWV 12.9 (4.2) m/s, mean (SD) CPP 69 (21) mm Hg, mean (SD) eGFR 68 (16) ml/min/1.73 m 2 , and median (IQR) ACR 3 (2-6) mg/g) were included in this study. At CPP greater than 85 mm Hg, a higher CPP was associated with a lower eGFR in unadjusted analyses but not after adjust-
doi:10.5694/mja14.00669 pmid:25390269 fatcat:6wppogsh3vb2lnr42aneolxag4
Stem Cell Reports
generated by genetic perturbation of multiple transcription regulators, including C-MYC, TP53, E6/E7, and SOX2, some of which must be exogenously extinguished before terminal maturation can proceed (Huang ...doi:10.1016/j.stemcr.2015.05.003 pmid:26028528 pmcid:PMC4471833 fatcat:xfvoxrqrc5cxncxic3wd4zyx2q
After 6 (P. japonica) or 24 (C. multipunctata) h we determined the area consumed. ... The area consumed after six (P. japonica) or 24 (C. multipunctata) h was determined. ...doi:10.1046/j.1570-7458.1997.00183.x fatcat:vyfpvtuejzcwbjezr54ihgd2xm
Epithelial removal was confirmed for each individual ring by microscopic observation of H&E-stained sections. qRT-PCR. ... (A) H&E-stained sections from tracheal rings with epithelium intact (arrow) or removed (arrowhead). The Journal of Clinical Investigation ...doi:10.1172/jci58815 pmid:22232213 pmcid:PMC3266785 fatcat:l44lg6rverfsrasvd7d5ngznri
It is therefore surprising that high field magnetization, torque, and resistivity measurements with H||c reveal two metamagnetic transitions at mu_0H_1 = 6.7 T and mu_0H_2 = 21 T. ... H at T = 1.8 K for H||ab (dashed line) and H||c (solid line) up to µ 0 H = 7 T. The c axis moment from neutron diffraction is given by the solid symbols. Inset shows the low-field data for H||ab. ... The MM transition at µ 0 H 1 moves up in field, from 6.7 T for H c to 10 T for H ab, and µ 0 H 2 moves above the available field range of 35 T for θ ∼ 62 degrees. ...arXiv:1803.04013v1 fatcat:bobcdbyy2raedg3fsv6e45l5y4
repetitive DNA was made up of 64 repeated sections of 86 nucleotides separated by one of eight 17-base linker segments in the following configuration: (R86-A -R86-B -R86-C -R86-D -R86-E -R86-F -R86-G -R86-H) ...doi:10.1101/2022.02.10.479955 fatcat:2awqed3qlvh5ndjukss3xcf6hi
Sciences; GenUn, genitourinary radiology; PCR, Philips computed radiography; Peds, pediatric radiology; RIS, radiology information systern (Reprinted from Computerized Medical Imaging & Graphics, Vol 17, Huang ...doi:10.1007/bf03168857 pmid:8734574 fatcat:2t2w3rwgrfbnzareynhjiuequa
The ISME Journal
The ISME Journal (2013) 7, 1876 & 2013 International Society for Microbial Ecology All rights reserved 1751-7362/13 www.nature.com/ismej Libusha Kelly, Huiming Ding, Katherine H Huang, Marcia S Osburne ...doi:10.1038/ismej.2013.92 pmcid:PMC3749510 fatcat:zu2slznypzgidaihqiluj4dwyq
« Previous Showing results 1 — 15 out of 4,534 results