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Antarctic sea ice elevation from satellite radar altimetry

Katharine A. Giles, Seymour W. Laxon, Anthony P. Worby
2008 Geophysical Research Letters  
A climatology of satellite ice elevation estimates is compared to an Antarctic sea ice thickness climatology made from the Antarctic Sea Ice Processes and Climate (ASPeCt) data set.  ...  We wish to thank A. Ridout, J. Gaudelli and N. Peacock for data processing and software development. This work was funded by the UK's National Environmental Research Council and the European Union.  ...  To calculate an average ice elevation, each grid cell (defined below) must contain at least ten individual elevation estimates, resulting in a maximum error of ±0.05 m [Giles and Hvidegaard, 2006 ]. [  ... 
doi:10.1029/2007gl031572 fatcat:j3fk4xk5mbdpne3maxl7y3zng4

Mean dynamic topography of the Arctic Ocean

Sinéad Louise Farrell, David C. McAdoo, Seymour W. Laxon, H. Jay Zwally, Donghui Yi, Andy Ridout, Katharine Giles
2012 Geophysical Research Letters  
Over the open ocean standard elevation data are used, while over sea ice the data are corrected for tracking errors using a "Gaussian + exponential" waveform model [Giles et al., 2007] .  ...  A dashed-white box outlines Region A. Figure 3 . 3 (a) Mean dynamic topography of the Arctic Ocean computed by differencing the ICEn MSS with the EMG2008 geoid.  ... 
doi:10.1029/2011gl050052 fatcat:ufv27fzk2zho5eonepsuppybda

Circumpolar thinning of Arctic sea ice following the 2007 record ice extent minimum

Katharine A. Giles, Seymour W. Laxon, Andy L. Ridout
2008 Geophysical Research Letters  
We estimated the errors in ice thickness for each grid cell as follows: The error in the ice freeboard was calculated using equation (1) from Giles and Hvidegaard [2006] , with an additional term to  ...  The error in the estimate of ice thickness in each grid cell was then calculated from equation (3) of Giles et al. [2007] , with errors in the ice and water densities taken to be 5 kg m À3 and 0.5 kg  ... 
doi:10.1029/2008gl035710 fatcat:rwyx7fgguvfy3k75i7gljmm5mq

Recent loss of floating ice and the consequent sea level contribution

Andrew Shepherd, Duncan Wingham, David Wallis, Katharine Giles, Seymour Laxon, Aud Venke Sundal
2010 Geophysical Research Letters  
Altogether, 746 ± 127 km 3 yr −1 of floating ice was lost between 1994 and 2004, a value that exceeds considerably the reduction in grounded ice over the same period.  ...  Although the losses are equivalent to a small (49 ± 8 mm yr −1 ) rise in mean sea level, there may be large regional variations in the degree of ocean freshening and mixing.  ...  This work was supported by the UK National Centre for Earth Observation and a Philip Leverhulme Prize to AS. We thank an anonymous reviewer for helpful comments on the manuscript.  ... 
doi:10.1029/2010gl042496 fatcat:tsam44e32nfpleie5i4nqropv4

A comprehensive review of heregulins, HER3, and HER4 as potential therapeutic targets in cancer

Jose Mauricio Mota, Katharine Ann Collier, Ricardo Lima Barros Costa, Timothy Taxter, Aparna Kalyan, Caio A. Leite, Young Kwang Chae, Francis J. Giles, Benedito A. Carneiro
2017 OncoTarget  
A. Neuregulin expression modulates clinical response to trastuzumab in patients with metastatic breast cancer.  ...  Although several trials have indicated an acceptable safety profile, translating preclinical findings into clinical practice remains a challenge in this field, possibly due to the complexity of downstream  ...  [1] The protein structure is comprised of an N-terminus motif, an Ig-like domain (HRG-1 types I and II and HRG-2), an EGF-like domain, a juxtamembrane domain, a transmembrane domain, and a cytoplasmic  ... 
doi:10.18632/oncotarget.18467 pmid:29179520 pmcid:PMC5687690 fatcat:iz4rn7gbkbeftm53g6rroy2dbq

The Potential of Nanoporous Anodic Aluminium Oxide Membranes to Influence Skin Wound Repair

Leigh G. Parkinson, Natalie L. Giles, Katharine F. Adcroft, Mark W. Fear, Fiona M. Wood, Gerard E. Poinern
2009 Tissue Engineering. Part A  
The suitability of the membrane to act as a dressing after a burn injury was assessed in vivo; application of the membrane demonstrated adherence and conformability to the skin surface of a pig, with no  ...  regular dimpled landscape that can act as a self-assembled template for a second anodization.  ...  A 'cell-free area' was created in a confluent cell layer, and migration of cells to cover the gap was monitored.  ... 
doi:10.1089/ten.tea.2008.0594 pmid:19527180 fatcat:q5cbguvth5g6tafryzie2xn5ky

Western Arctic Ocean freshwater storage increased by wind-driven spin-up of the Beaufort Gyre

Katharine A. Giles, Seymour W. Laxon, Andy L. Ridout, Duncan J. Wingham, Sheldon Bacon
2012 Nature Geoscience  
We observe a positive SSH trend and show that the trend in the wind field has a corresponding spatial pattern, indicating that wind-driven convergence controls freshwater variability.  ...  We calculate a freshwater increase of 8000±2000 km 3 over the Western Arctic, in keeping with hydrographic observations 4,5 .  ...  Supplementary Information for "Western Arctic Ocean freshwater storage increased by wind-driven spin-up of the Beaufort Gyre" by Giles et al., katharine.giles@ucl.ac.uk Methods To estimate an elevation  ... 
doi:10.1038/ngeo1379 fatcat:rzbi2kmqvbdijn2j6ed6n7xc3i

Brain stem gliomas: Patterns of Care in Victoria from 1998–2000

Mark A. Rosenthal, David M. Ashley, Katharine J. Drummond, Michael Dally, Michael Murphy, Lawrence Cher, Vicky Thursfield, Graham G. Giles
2008 Journal of clinical neuroscience  
Paediatric cases were identified from a retrospective analysis of the Victorian Paediatric Brain tumour database for the same period.  ...  Nine (38%) did not have a histologic diagnosis but were diagnosed on the basis of radiological appearance. Complete macroscopic resection was performed in two patients (8%).  ...  Indeed, the diagnosis of a brainstem glioma almost always precludes a patient from a systemic therapy trial.  ... 
doi:10.1016/j.jocn.2007.04.008 pmid:18226529 fatcat:u5jjkiy2dbeghbevy6fktovpuq

CryoSat-2 estimates of Arctic sea ice thickness and volume

Seymour W. Laxon, Katharine A. Giles, Andy L. Ridout, Duncan J. Wingham, Rosemary Willatt, Robert Cullen, Ron Kwok, Axel Schweiger, Jinlun Zhang, Christian Haas, Stefan Hendricks, Richard Krishfield (+3 others)
2013 Geophysical Research Letters  
For echoes from leads, we replace the simple leading edge threshold algorithm used previously [Giles et al., 2008] , with a more sophisticated Gaussian plus exponential model fit to the echo [Giles et  ...  Surface type detection is implemented by examining the "pulse peakiness" (PP) parameter used previously [Giles et al., 2008; Peacock and Laxon, 2004 ] and a new parameter, known as the "stack standard  ... 
doi:10.1002/grl.50193 fatcat:5r2ztzj2hzdt5eofqk27czctky

Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma

Richa Rathore, Katharine E. Caldwell, Charles Schutt, Caitlyn B. Brashears, Bethany C. Prudner, William R. Ehrhardt, Cheuk Hong Leung, Heather Lin, Najat C. Daw, Hannah C. Beird, Abigail Giles, Wei-Lien Wang (+4 others)
2021 Cell Reports  
Identifying a therapeutic combination for PHGDH-high cancers offers preclinical justification for a dual metabolism-based combination therapy for osteosarcoma.  ...  PHGDH inhibition in osteosarcoma cell lines attenuated cellular proliferation without causing cell death, prompting a robust metabolic analysis to characterize pro-survival compensation.  ...  A study from St.  ... 
doi:10.1016/j.celrep.2020.108678 pmid:33503424 pmcid:PMC8552368 fatcat:4cpza2hcondlrc3xrqro5k3sly

Page 443 of The Westminster Review Vol. 164, Issue 4 [page]

1905 The Westminster Review  
But in all probability it means nothing more than that the poet wanted a rhyme. We must not be too hard upon Giles.  ...  But he was a literary man, and the fortunes of Katharine and her daughter did not weigh much in comparison with the necessity of winging with royal favour the shaft that was to gall the flank of a patronising  ... 

Mercer Land Book

Kate Mason Rowland
1905 The William and Mary quarterly  
Giles Brent," No. 27, 1651. Deed to Giles Brent, Nov. 17, 1662. GOOSE CREEK, 436 ACRES. Grant to Katharine Brent from Sir Wim.  ...  Edmund Brent left by Will to his daughter, Katharine Brent, Dec. 9, 1662.  ... 
doi:10.2307/1916084 fatcat:3od2olo2qbbljpypepbzrx434u

Page 909 of Arena Vol. 10, Issue 6 [page]

1894 Arena  
‘“*A Sarnt,” translated by Katharine Prescott Wormeley, from Paul Bourget’s ‘‘ Pastels of Men.’ Cloth; pp. 82; price $1.  ...  ‘““NATURE OF SPIRIT, AND MAN AS A SPIRITUAL BEtNG,” by Rev. Chauncey Giles. Paper; pp. 206. Published by the New Church Board of Publication, New York. “MARRIAGE AND Dtvorce,” by Henry C. Whitney.  ... 

Page 205 of American Genealogist Vol. 22, Issue 4 [page]

1946 American Genealogist  
Eleazer" Giles.  ...  Katharine ————; John? m. Sarah?® Thompson; Jacob® m. Margery® Hayward; Mercy* m. Israel Taft. ALLEN. James! m. Ann Guild; Nathaniel? m. Mary? Friz- zell; Ebenezer? m. Mary* Hill; Mary* m.  ... 

Page 629 of The Gentleman's Magazine Vol. 83, Issue [page]

1813 The Gentleman's Magazine  
Katharine Colemanl7 10/St. Michael Cornhil...11 7 St. Alphage .........00. 40 221St. Katharine Crechur.25 19) %t. Michael Crookedla. 5 5 St. Andrew Hubbard... 6 3/S:. Lawrence Jewry... 6 4)St.  ...  SEND you a Transcript of the Weekly Bill of Mortality from the 29th of August to the 5th of September 1665, the largest Week of the Great Plague. Yours, &c. E. London 37.  ... 
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