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Recent Advances on Small-Molecule Epidermal Growth Factor Receptor Inhibitors
2020
Medicine Research
Preserved Fulltext
The epidermal growth factor receptor (EGFR) is a kind of cell membrane surface receptor with tyrosine kinase activity, which is closely related to the growth, proliferation, differentiation, apoptosis, metastasis and other processes of tumor cells. Targeting EGFR tyrosine kinase inhibitors has become a hot topic for drug development for treatment of non-small-cell cancer (NSCLC). Herein, we summarized recent advances on the targeted therapeutic drugs for NSCLC in recent years.
doi:10.21127/yaoyimr20200011
fatcat:jf2u7ulrajgzfawqqyx5wjeaga
Extracranial Internal Carotid Artery Tortuosity and Body Mass Index
2017
Frontiers in Neurology
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Copyright © 2017 Wang, Wang, Wang, Wang, Lu, Qi, Hu, Yang and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). ...
doi:10.3389/fneur.2017.00508
pmid:28993755
pmcid:PMC5622293
fatcat:qrvler5vtzgm3gq76lm23jdjo4
Co-detection in the pathogenesis of severe hand-foot-mouth disease
2012
Archives of Virology
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Contributorship statement Li-Juan Liu and Hong-Mei Xu wrote the manuscript and finished the lab work; Xiu-Jun Li, Jun Wang, Xian-Jun Wang and Shu-Jun Ding collected the specimens and sent them to the lab ...
Fang Tang and Jing Wang gave advice when revising the manuscript.
Table 1 1 Logistic analysis of the relationship between the detected viruses and severe HFMD CI, confidence interval. ...
doi:10.1007/s00705-012-1396-6
pmid:22791110
pmcid:PMC3488190
fatcat:zflhzoltijds5pp5vk4jw6z4n4
Modification of AFM Tips for Facilitating Picking-up of Nanoparticles
2008
Chinese Physics Letters
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The radius of atomic force microscope (AFM) tip is a key factor that influences nonspecific interactions between AFM tip and nanoparticles. Generally, a tip with larger radius contributes to a higher efficiency of picking up nanoparticles. We provide two methods for modifying the AFM tip: one is to wear a tip apex on a solid substrate and the other is to coat a tip with poly (dimethylsiloxane) (PDMS). Both the approaches can enhance the adhesion force between the tip and nanoparticles by
doi:10.1088/0256-307x/25/7/021
fatcat:brrpakqpfnfhjk4ztfgwnvdanm
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... ing tip radius. The experimental results show that a modified tip, compared to an unmodified one, achieves six-fold efficiency improvement in the capture of targeted colloidal gold nanoparticles.
Characterization of soybean genomic features by analysis of its expressed sequence tags
2004
Theoretical and Applied Genetics
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40
20
20
213,535
5.338
Hauge BM, Wang ML,
Parsons JD, Parnell LD
Total
169
97
72
1,026,599
6.074
Hauge BM, Wang ML,
Parsons JD, Parnell LD
a ...
ML,
Parsons JD, Parnell LD
AX196296
48
26
22
335,913
6.998
Hauge BM, Wang ML,
Parsons JD, Parnell LD
AX196297
60
38
22
349,954
5.832
Hauge BM, Wang ML,
Parsons JD, Parnell LD
AX223856 ...
doi:10.1007/s00122-003-1499-2
pmid:14624337
fatcat:vxjh45qxzne4je4a4i4xnvhyem
Uniting the order and disorder dynamics in photoexcited VO2
[article]
2021
arXiv
pre-print
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-S. & Wang, L.-W. ...
Suo1,2, Zhi Wang1, Jun-Wei Luo1,2*, Shu-Shen
Li1,2, and Lin-Wang Wang3*
1
State Key Laboratory of Superlattices and Microstructures, Institute of ...
arXiv:2112.02463v1
fatcat:5bfyjgqvavcffgsf6eag2syefy
Ghost Panorama
[article]
2021
arXiv
pre-print
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Computational ghost imaging or single-pixel imaging enables the image formation of an unknown scene using a lens-free photodetector. In this Letter, we present a computational panoramic ghost imaging system that can achieve the full-color panorama using a single-pixel photodetector, where a convex mirror performs the optical transformation of the engineered Hadamard-based circular illumination pattern from unidirectionally to omnidirectionally. To our best knowledge, it is the first time to
arXiv:2108.10122v1
fatcat:mbvz2pa7wbabtaeto37l4btwzu
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... ose the concept of ghost panorama and realize preliminary experimentations. It is foreseeable that ghost panorama will have more advantages in imaging and detection in many extreme conditions (e.g., scattering/turbulence, cryogenic temperatures, and unconventional spectra), as well as broad application prospects in the positioning of fast-moving targets and situation awareness for autonomous vehicles.
Generalised Reliability On Hydro-Geo Objects
2015
Open Civil Engineering Journal
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Chinese scholars such as Chen and Liu (1990) [3] and Wang and Chen (1996) [4] offer some original achievements in this area. ...
There have been many numerical algorithms that treat the randomness of X (Lü and Feng 1997; Chen and Liu 1990; Wang and Chen 1996; Zhuo 2000; Christian and Baecher 1999) [2] [3] [4] [5] [6] . ...
doi:10.2174/1874149501509010498
fatcat:wh6fkveb5zettauaadpv7mstye
Influence Of Spot Size On LA-ICP-MS Ablation Behavior For Synthetic Calcium Tungstate And Silicate Glass Reference Material NIST SRM 610
Yuting Xiao,Jian Yang,Jun Deng,Wei Wang,Yuqiu Ke*,Yijian Sun
2021
Atomic spectroscopy
Yuting Xiao,Jian Yang,Jun Deng,Wei Wang,Yuqiu Ke*,Yijian Sun
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Laser ablation behaviors are typically influenced by the laser operating parameters like the spot size, which has been well studied for silicate glass reference materials but not for samples, such as scheelite, which has the chemical composition of CaWO4. In this work, the ablation behaviors of synthetic CaWO4 single crystal CaW-1 were studied and compared with those of the well-studied NIST SRM 610 silicate glass reference material. The results showed that LA-ICP-MS analysis of both the CaW-1
doi:10.46770/as.2021.01.006
fatcat:44cd6p5m5jcqxd6t3czeqnnhj4
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... nd NIST SRM 610 can obtain desired ablation craters and expected signal intensity ratios (R) with a spot size of 60, 44, or 32 μm, while it is not possible with the spot size of 10, 16, or even 90 μm due to the tapered craters or below-expected ablation efficiency/aerosol transport efficiency. Elemental fractionation was found for both CaW-1 and NIST SRM 610 at the small spot size. A spot size of ≥32 μm is preferred for CaW-1, and even for scheelite regardless of pulse number, while a spot size of 16 μm is desirable for NIST SRM 610 with the pulse number of 200, but a spot size of 44 μm is recommended as the pulse number increases to 300.
Measurement of the fine structure of cesium Rydberg state
2017
Wuli xuebao
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铯原子里德伯态精细结构测量 * 裴栋梁 1)2) 何军 1)2)3) † 王杰英 1)2) 王家超 1)2) 王军民 1)2)3) ‡ 1) (山西大学光电研究所, 太原 030006) 2) (山西大学, 量子光学与光量子器件国家重点实验室, 太原 030006) 3) (山西大学, 极端光学协同创新中心, 太原 030006) ( 2017 年 4 月 20 日收到; 2017 年 7 月 6 日收到修改稿 ) 里德伯态光谱是测量里德伯态能级结构和中性原子间相互作用的常用技术手段, 特别是高精度的里德伯 光谱, 可以测量室温原子气室中由偶极相互作用等导致的原子能级频移. 在实验中利用反向的 852 nm 激光和 509 nm 激光实现了室温原子气室中铯原子 6S 1/2 -6P 3/2 -57S(D) 跃迁的级联双光子激发, 实现了里德伯态 原子的制备. 基于阶梯型电磁诱导透明获得了铯原子里德伯态的高分辨光谱. 实验中, 基于速度选择的射频 边带调制技术, 对光谱信号进行了频率标定, 测量了铯原子里德伯态 57D 3/2 和 57D 5/2 的精细分裂, 分裂间隔 为
doi:10.7498/aps.66.193701
fatcat:3nwzwkn5urdzzc5zqvufltpi44
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... ± 2.5) MHz, 与理论计算结果基本一致. 速度选择的射频调制光谱可以实现里德伯态原子的能级分 裂测量, 其测量精度对于单光子跃迁的绝对激光频率不敏感; 实验中影响 57D 3/2 和 57D 5/2 精细分裂间隔测 量精度的主要因素是功率加宽导致的电磁感应透明信号的展宽和 509 nm 激光频率扫描的非线性.
Effect of Ca addition on solidification microstructure of hypoeutectic Al-Si casting alloys
2019
China Foundry
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Wang et al. [28] investigated that the crystallographic orientation relationships between α-Al and Al 2 Cu was {211}Al 2 Cu||{111} Al and <120>Al 2 Cu||<110>Al. ...
doi:10.1007/s41230-019-9014-9
fatcat:yhfahit4q5eflmzuekhestavsq
Regulatory Roles of Non-Coding RNAs in Colorectal Cancer
2015
International Journal of Molecular Sciences
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Jun Wang and Yong-Xi Song contributed equally to this work. Jun Wang and Yong-Xi Song contributed to drafting and editing of the manuscript. ...
Bin Ma, Jia-Jun Wang and Jing-Xu Sun participated in the conception of the idea. Xiao-Wan Chen, Jun-Hua Zhao and Yu-Chong Yang contributed to the literature search. ...
doi:10.3390/ijms160819886
pmid:26307974
pmcid:PMC4581331
fatcat:xoogwein5rdahf3napau6ed4rq
Reply to Comment on "Tip induced unconventional superconductivity on Weyl semimetal TaAs"
[article]
2016
arXiv
pre-print
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magnetoresistance, particularly because the point contact is a completely different phase
(superconducting)"
Here we show some representative spectra where features similar to that obtained on TaAs by Wang ...
arXiv:1607.02886v1
fatcat:dkd7cceimveqhcu4bjzst5vg2y
Photoinduced charge density wave transition like a puppet on a string
[article]
2021
arXiv
pre-print
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Photoinduced charge density wave transition like a puppet on a
string
Zhao-Jun Suo1,2, Wen-Hao Liu1,2, Zhi Wang1, Hao-Wen Liu1,2, Jun-Wei Luo1,2,3 ...
Wang, S.-S. Li, and L.-W. Wang, Phys. Rev. Lett. 114, 063004 (2015).
[58] http://www.pwmat.com.
[59] J. Ma, Z. Wang, and L.-W. ...
arXiv:2112.12289v1
fatcat:sti77nkkq5fsnhgn5lkbdmulwm
Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells
2016
International Journal of Nanomedicine
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