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Clinical bioinformatics: a new emerging science
2011
Journal of Clinical Bioinformatics
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Welcome to the open-access journal titled Journal of Clinical Bioinformatics (JCBi), a truly international journal devoted to clinical applications of bioinformatics, medical informatics and the development ...
JCBi is the only journal focusing on the clinical application of bioinformatics and keeping track of the wealth of new information related to this topic. ...
Submit your next manuscript to BioMed Central and take full advantage of: ...
doi:10.1186/2043-9113-1-1
pmid:21884620
pmcid:PMC3097094
fatcat:66zfijcvwren3bdldfbnexzgle
Role of clinical bioinformatics in the development of network-based Biomarkers
2011
Journal of Clinical Bioinformatics
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A number of methodologies and computational programs have been developed to integrate selected proteins into the knowledge-based networks via the combination of genomics, proteomics and bioinformatics. ...
Dynamic network biomarkers should be furthermore correlated with clinical informatics, including patient complaints, history, therapies, clinical symptoms and signs, physician's examinations, biochemical ...
Clinical bioinformatics has been suggested as a new emerging science combining clinical informatics, bioinformatics, medical informatics, information technology, mathematics and omics science together ...
doi:10.1186/2043-9113-1-28
pmid:22024468
pmcid:PMC3221619
fatcat:h66h2jstl5e6zlisqq76waruei
Brain cancer prognosis: independent validation of a clinical bioinformatics approach
2012
Journal of Clinical Bioinformatics
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The clinical information hidden in these data can be clarified with clinical bioinformatics approaches. ...
Translational and evidence based medicine can take advantage of biotechnology advances that offer a fast growing variety of high-throughput data for screening molecular activities of genomic, transcriptional ...
Second, it offers a useful analysis tool in the clinical bioinformatics research area. ...
doi:10.1186/2043-9113-2-2
pmid:22297051
pmcid:PMC3296594
fatcat:wzikpz7vhbbtneb4fqk7663ygm
Reverse translational bioinformatics: a bioinformatics assay of age, gender and clinical biomarkers
2008
Summit on translational bioinformatics
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In bioinformatics, clinical data is rarely used. Here, we propose using bedsidedata in basic research, via bioinformatics methodologies. ...
To demonstrate the potential of this so called Reverse Translational Bioinformatics approach, classical bioinformatics tools were applied to blood biomarker information attained from a large scale, open-access ...
This work was supported by the Horowitz Center for Complexity Science, the RICH foundation and the National Institute of Biotechnology in the Negev. ...
pmid:21347121
pmcid:PMC3041524
fatcat:wskvhfng3rgpnopyinw7xibaha
Significance of bioinformatics in research of chronic obstructive pulmonary disease
2011
Journal of Clinical Bioinformatics
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We also presented the requirements and challenges in implementing bioinformatics to COPD research and interpreted these results as clinical physicians. ...
As an interdispline, bioinformatics supplied vital information on integrative understanding of COPD. ...
Clinical bioinformatics on COPD could be achieved from the combination of clinical informatics, medical informatics, bioinformatics and informatics by collaborations among clinicians, bioinformaticians ...
doi:10.1186/2043-9113-1-35
pmid:22185624
pmcid:PMC3285039
fatcat:ncwr3gw2rvexpmffl6quxa6ofq
ObTiMA
2015
Journal of Clinical Bioinformatics
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Display of creating a CRF to register a patient in the SIOP trial. ...
Tool description ObTiMA is an ontology-based clinical trial data management system [1] to support clinicians in designing and conducting clinical trials. ...
The ontology-based CRF (case report form) creation module of the Trial Builder is one of the systems core functionalities ( Figure 1 ). ...
doi:10.1186/2043-9113-5-s1-s3
pmcid:PMC4460786
fatcat:projkhk2qfgaphjupiujzsaesq
Decima
2015
Journal of Clinical Bioinformatics
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Status of development
Users Oncologists, trial nurses, investigators, clinical researchers. Version 3 ( 3 June 2014). ...
We address both aspects and propose a scalable, efficient and pragmatic application enabling automatic evaluation of eligibility of patients for a relevant set of clinical trials (Figure 1 ). ...
doi:10.1186/2043-9113-5-s1-s11
pmcid:PMC4460922
fatcat:njbawrwfkjdqnmlmudyahbqake
Bioinformatic-driven search for metabolic biomarkers in disease
2011
Journal of Clinical Bioinformatics
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This review demonstrates that clinical bioinformatics has evolved into an essential element of biomarker discovery, translating new innovations and successes in profiling technologies and bioinformatics ...
This survey article highlights emerging bioinformatics methods for biomarker discovery in clinical metabolomics, focusing on the problem of data preprocessing and consolidation, the data-driven search, ...
Acknowledgements The authors gratefully acknowledge support from the Austrian Genome Research Program GEN-AU and its "Bioinformatics Integration Network (BIN III)" project. ...
doi:10.1186/2043-9113-1-2
pmid:21884622
pmcid:PMC3143899
fatcat:cji7s2zn3vbz5p5irjb45xykqu
Clinical Proteomics Perspective
2015
Journal of Proteomics & Bioinformatics
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Clinical Proteomics is a special peer-reviewed proteomics journal published as a special issue this year by Journal of Proteomics and Bioinformatics. ...
Journal of Proteomics and Bioinformatics is an open access, peerreviewed, online journal considering research in proteomics. ...
doi:10.4172/jpb.s8-e001
fatcat:gatp3tihdfbblgoghmnves3uoe
Brachyury goes Clinical
2012
Journal of Proteomics & Bioinformatics
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Completion of the clinical trial will definitely tell a lot more in this field of study, but continuation of Brachyury to be studied in basic science, is still needed to answer many questions. ...
These steps usually involve many years of basic science research, financial support, and yet no conclusion for a clinical trial. ...
doi:10.4172/jpb.10000e20
fatcat:2ys5zqedfnbpfervxumofvgfoy
Clinical trials information mediator (CTIM)
2015
Journal of Clinical Bioinformatics
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Results of a query for "informed consent" is shown. Left side indicates NCT numbers; the right side offers links to ClinicalTrials.gov. ...
Journal of Clinical Bioinformatics 2015 5(Suppl 1):S7. ...
Braasch and Karakoyun Journal of Clinical Bioinformatics 2015, 5(Suppl 1):S7 http://www.jclinbioinformatics.com/content/5/S1/S7
Status of development this article as: Braasch and Karakoyun: Clinical ...
doi:10.1186/2043-9113-5-s1-s7
pmcid:PMC4460620
fatcat:n5hsjydv7rfrjjgrhxbiw6hpli
Section 7: Bioinformatics: Bioinformatics and its Impact on Clinical Research Methods
2006
IMIA Yearbook of Medical Informatics
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Results: Current research in the field of bioinformatics clearly shows ongoing unification of experimental findings and clinical outcomes. ...
Examination of appropriate methods covers data and text mining, ontologies as well as machine learning and classification.The best paper selection of articles on bioinformatics shows examples of excellent ...
Acknowledgement We greatly acknowledge the support of Martina Hutter and of the reviewers in the selection process of the IMIA Yearbook. ...
doi:10.1055/s-0038-1638478
fatcat:kwwamrqcffbbzaasbwpo5hq76e
EHR4CR local workbench
2015
Journal of Clinical Bioinformatics
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Characterisation Tool, recruitment process, multi-centric clinical trials. ...
Journal of Clinical Bioinformatics 2015 5(Suppl 1):S12. ...
Voets Journal of Clinical Bioinformatics 2015, 5(Suppl 1):S12 http://www.jclinbioinformatics.com/content/5/S1/S12 From 1st Clinical Research Informatics (CRI) Solutions Day Duesseldorf, Germany. 26-27 ...
doi:10.1186/2043-9113-5-s1-s12
pmcid:PMC4460753
fatcat:vmajhab6y5bjra5pxlifyhqun4
VISTA Trials
2015
Journal of Clinical Bioinformatics
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EORTC, Avenue Emmanuel Mounier 83/11, 1200 Brussels, Belgium Gilotay and Lejeune Journal of Clinical Bioinformatics 2015, 5(Suppl 1):S4 http://www.jclinbioinformatics.com/content/5/S1/S4
JOURNAL OF ...
Display of ClinicalData module indicating a check for correctness of data input (in red).
this article as: Gilotay and Lejeune: VISTA Trials. Journal of Clinical Bioinformatics 2015 5(Suppl 1):S4. ...
doi:10.1186/2043-9113-5-s1-s4
pmcid:PMC4460619
fatcat:rxagtdgo2jb6xpcsni22vt2gyi
EHR4CR central workbench
2015
Journal of Clinical Bioinformatics
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Characterisation Tool, protocol feasibility, recruitment process, electronic data capture, multi-centric clinical trials. ...
Correspondence: david.voets@custodix.com Custodix, Kortrijkse steenweg 214, bus 3, 9830 Sint-Martens-Latem, Belgium Figure 1 User interface of the central workbench showing different eligibility criteria ...
The study manager is automatically informed about relevant changes occurring at each of the engaged clinical sites such as changes in the number of potential candidate patients, the number of consenting ...
doi:10.1186/2043-9113-5-s1-s13
pmcid:PMC4460653
fatcat:2xuwqsxkgbdlzett66fbn5jfyq
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