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Updates in Rhea – an expert curated resource of biochemical reactions

Anne Morgat, Thierry Lombardot, Kristian B. Axelsen, Lucila Aimo, Anne Niknejad, Nevila Hyka-Nouspikel, Elisabeth Coudert, Monica Pozzato, Marco Pagni, Sébastien Moretti, Steven Rosanoff, Joseph Onwubiko (+4 others)
2016 Nucleic Acids Research  
Rhea (http://www.rhea-db.org) is a comprehensive and non-redundant resource of expert-curated biochemical reactions designed for the functional annotation of enzymes and the description of metabolic networks. Rhea describes enzyme-catalyzed reactions covering the IUBMB Enzyme Nomenclature list as well as additional reactions, including spontaneously occurring reactions, using entities from the ChEBI (Chemical Entities of Biological Interest) ontology of small molecules. Here we describe
more » ... ents in Rhea since our last report in the database issue of Nucleic Acids Research. These include the first implementation of a simple hierarchical classification of reactions, improved coverage of the IUBMB Enzyme Nomenclature list and additional reactions through continuing expert curation, and the development of a new website to serve this improved dataset.
doi:10.1093/nar/gkw1299 pmid:27980062 pmcid:PMC5397180 fatcat:jzdvhp7ldrdunmqr4ezr4z5jw4

Effect of electronic banking on financial performance of deposit money banks in Nigeria

Joseph Madugba, Ben-Caleb Egbide, Dike Wozuru Jossy, Uche Toby Agburuga, Onwubiko Onyebuchi Chibunna
2021 Banks and Bank Systems  
The impact of technology on commerce cannot be denied, especially in relation to trade. This study was conducted to examine the impact of electronic banking on the financial performance of Nigerian deposit money banks. The data for the study was obtained from the Central Bank of Nigeria's Statistical Bulletin and the National Bureau of Statistics' Statistical Bulletin for various years, as well as from published financial statements of the banks under study. An ex-post facto research design was
more » ... used and a normality test was carried out to establish the goodness of the data; descriptive statistics and a multicollinearity test were conducted in which the independent variables were found good. Regression was adopted to test two hypotheses. It was found that ATM has a positive and significant association with Earning EPS and ROA; POS and NEFT significantly affect ROA only, while WEB has an insignificant impact on both EPS and ROA. It is concluded that electronic banking significantly affects financial performance of deposit money banks in Nigeria. Thus, the study recommended that deposit money banks in Nigeria should educate their customers more in the use of NEFT, WEB, and POS, and that the amount of ATM withdrawals should be increased to improve bank performance.
doi:10.21511/bbs.16(3).2021.07 fatcat:eumisnvydfaopeg5izp7zylnym

Updates in Rhea – an expert curated resource of biochemical reactions

Anne Morgat, Thierry Lombardot, Kristian B. Axelsen, Lucila Aimo, Anne Niknejad, Nevila Hyka-Nouspikel, Elisabeth Coudert, Monica Pozzato, Marco Pagni, Sébastien Moretti, Steven Rosanoff, Joseph Onwubiko (+4 others)
2016 Nucleic Acids Research  
Rhea (http://www.rhea-db.org) is a comprehensive and non-redundant resource of expert-curated biochemical reactions designed for the functional annotation of enzymes and the description of metabolic networks. Rhea describes enzyme-catalyzed reactions covering the IUBMB Enzyme Nomenclature list as well as additional reactions, including spontaneously occurring reactions, using entities from the ChEBI (Chemical Entities of Biological Interest) ontology of small molecules. Here we describe
more » ... ents in Rhea since our last report in the database issue of Nucleic Acids Research. These include the first implementation of a simple hierarchical classification of reactions, improved coverage of the IUBMB Enzyme Nomenclature list and additional reactions through continuing expert curation, and the development of a new website to serve this improved dataset.
doi:10.1093/nar/gkw990 pmid:27789701 pmcid:PMC5210663 fatcat:26f75w5d6zdpbh4kzsom6la2ka

The EBI enzyme portal

Rafael Alcántara, Joseph Onwubiko, Hong Cao, Paula de Matos, Jennifer A. Cham, Jules Jacobsen, Gemma L. Holliday, Julia D. Fischer, Syed Asad Rahman, Bijay Jassal, Mikael Goujon, Francis Rowland (+9 others)
2012 Nucleic Acids Research  
The availability of comprehensive information about enzymes plays an important role in answering questions relevant to interdisciplinary fields such as biochemistry, enzymology, biofuels, bioengineering and drug discovery. At the EMBL European Bioinformatics Institute, we have developed an enzyme portal (http://www.ebi.ac.uk/enzymeportal) to provide this wealth of information on enzymes from multiple in-house resources addressing particular data classes: protein sequence and structure,
more » ... , pathways and small molecules. The fact that these data reside in separate databases makes information discovery cumbersome. The main goal of the portal is to simplify this process for end users.
doi:10.1093/nar/gks1112 pmid:23175605 pmcid:PMC3531056 fatcat:azpfa7qxrfewpd2ljiqn6peozq

Sustained effect of couples' HIV counselling and testing on risk reduction among Zambian HIV serodiscordant couples

Kristin M Wall, William Kilembe, Bellington Vwalika, Lisa B Haddad, Shabir Lakhi, Udodirim Onwubiko, Naw Htee Khu, Ilene Brill, Roy Chavuma, Cheswa Vwalika, Lawrence Mwananyanda, Elwyn Chomba (+3 others)
2017 Sexually Transmitted Infections  
We present temporal trends in selfreported and biological markers of unprotected sex and sex with concurrent partners in discordant couples receiving couples' voluntary HIV counselling and testing (CVCT). Methods Heterosexual Zambian HIV-serodiscordant couples were enrolled into longitudinal follow-up in an open cohort (1994)(1995)(1996)(1997)(1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010)(2011)(2012). Multivariable Anderson-Gill models explored predictors of
more » ... report and biological indicators of unprotected sex within (including sperm on a vaginal swab, incident pregnancy or incident linked HIV infection) and outside (including self-report, STI and unlinked HIV infection) the union. Measures of secular trends in baseline measures were also examined. Results At enrolment of 3049 couples, men were 35 years old on average, women were 29 years, and couples had been together for an average of 7 years. M+F− couples reported an average of 16.6 unprotected sex acts in the 3 months prior to enrolment ( pre-CVCT), dropping to 5.3 in the >0-3 month interval, and 2.0 in >6 month intervals ( p-trend <0.001). Corresponding values for M−F+ couples were 22.4 unprotected sex acts in the 3 months prior enrolment, dropping to 5.2 in the >0-3 month interval, and 3.1 in >6 month intervals ( p-trend <0.001). Significant reductions in self-report and biological markers of outside partners were also noted. Predictors of unprotected sex between study partners after CVCT included prevalent pregnancy (adjusted HR, aHR=1.6-1.9); HIV+ men being circumcised (aHR=1.2); and HIV− women reporting sex with outside partners (aHR=1.3), alcohol (aHR=1.2), injectable (aHR=1.4) or oral (aHR=1.4) contraception use. Fertility intentions were also predictive of unprotected sex (aHR=1.2-1.4). Secular trends indicated steady declines in reported outside partners and STIs. Conclusion Reductions in self-reported unprotected sex after CVCT were substantial and sustained. Reinforced risk-reduction counselling in pregnant couples, couples desiring children and couples with HIV− women having outside partners or using alcohol or injectable or oral contraception are indicated.
doi:10.1136/sextrans-2016-052743 pmid:28082662 pmcid:PMC5520263 fatcat:yme5indt4ngffi5rkzkwpb573m

Cyber Security Monitoring in India by Probability Calculation

Ranjana Patel, Rajendra Arakh
2022 Zenodo  
Cyril Onwubiko et al.  ...  Joseph Kaberuka et al. [12] Cyber security incidents are a growing threat to the health care industry.  ... 
doi:10.5281/zenodo.6345327 fatcat:dazohncn75fdti63rk7md5fvje

The Fruitless Branch and the Eternal Security of the Believer

Anthony Yaw Badu, Jonathan Kuwornu-Adjaottor
2022 E-Journal of Religious and Theological Studies  
Onwubiko strongly affirms that regardless of the lifestyle of the believer, he will be saved.  ...  Onwubiko argues that since salvation is not based on works but on grace it is therefore difficult for legalistic believers to get over the doctrine of eternal security.  ... 
doi:10.38159/erats.2022821 fatcat:vkgyodkx3zhynia3c2rds5vf6a

The EBI search engine: EBI search as a service—making biological data accessible for all

Young M. Park, Silvano Squizzato, Nicola Buso, Tamer Gur, Rodrigo Lopez
2017 Nucleic Acids Research  
Onwubiko for input to the Enzyme Portal and Peter Walter and Ken Hawkins for UX on the new GUI.  ...  Riverol, for the development of ideas and algorithms in the context of the OmicsDI portal; Anton Petrov, Matloob Qurechi, Simon Potter and Gift Nuka for input in relation to RNAcentral, InterPro and HMMER; Joseph  ... 
doi:10.1093/nar/gkx359 pmid:28472374 pmcid:PMC5570174 fatcat:7vlgpmowhrgcvjhqn2sk7w4hse

Universal Basic Education in Nigeria: An Exploration of the Grounds of Misgivings

Joseph Izuchukwu Kanu, Chioma Uchenna
2013 Journal of Educational and Social Research  
It is like Onwubiko (1991: x) wrote "education within the culture itself is a dual and sometimes simultaneous process of acculturation and enculturation."  ...  People like Obi C.A, Nwosu A.V., Eke C., Onwubiko KBC, Okon F.E., (1985) who had argued against secularization in the Nigerian education would see the UBE simply as Government's efforts to achieve perfect  ... 
doi:10.5901/jesr.2013.v3n4p69 fatcat:5vszbmsygna3haedzhwhq52zpi

The Visual Design of Network Data to Enhance Cyber Security Awareness of the Everyday Internet User

Fiona Carroll, Phil Legg, Bastian Bonkel
2020 2020 International Conference on Cyber Situational Awareness, Data Analytics and Assessment (CyberSA)  
Dr Cyril Onwubiko Dr Cyril Onwubiko -IEEE Computer Society Distinguished Visitor Program (DVP) Speaker & Director, Enterprise Security Architecture, Pearson Plc Dr Cyril Onwubiko is IEEE Computer  ...  data: A Twitter text mining approach to the communication of universities during the Lebanese protests Katia Raya 1 , Nicole D'almeida 2 and Maroun Chamoun 3 1 CELSA -ESIB Sorbonne University -Saint Joseph  ... 
doi:10.1109/cybersa49311.2020.9139668 dblp:conf/cybersa/CarrollLB20 fatcat:mtrvk2uvknadrosalvit4xz67i

The Impacts of Culture and Religion, Ethnicity, Politics and Poverty on Ethnic Violence in Plateau State of Nigeria

Azalahu F Akwara, Joseph E Udaw, Ngozi F Akwara, Jane Onimawo
2013 Mediterranean Journal of Social Sciences  
The Fulani jihadists in Nigeria were on a state and empire building adventure; and in search for greener pastures or economic resources (Onwubiko, 1973) .  ...  Then, trade and evangelisation and quest for natural resources also led to attacks and occupation of raided regions (Mangut, 2012; Onwubiko, 1976; Ifemesia, 1965; Aderingbe, 1965; Tamuno, 1965) .  ... 
doi:10.5901/mjss.2013.v4n14p657 fatcat:asbvp2c5yrefhiawsrfx5n3xbe

Nasopharyngeal pneumococcal carriage rates among HIV-infected adults following widespread pediatric use of conjugate pneumococcal vaccine-13

Theresa D. Feola, Cynthia A. Bonville, Donald A. Cibula, Sherly Jose, Geetha Nattanmai, Joseph B. Domachowske, Manika Suryadevara
2016 Human Vaccines & Immunotherapeutics  
Similarly, Onwubiko found no differences between the HIV-infected adults who were and were not colonized with pneumococcus following use of PCV7. 11 Interestingly, while low CD4 count (200 cells/mm 3  ... 
doi:10.1080/21645515.2016.1172758 pmid:27215541 pmcid:PMC5074599 fatcat:k26d2poblvd47i4hf2y7wi6ewe

Cyber Security 2020 Front Matters

2020 2020 International Conference on Cyber Security and Protection of Digital Services (Cyber Security)  
v The Cyber Science 2020 conference was opened by Dr Cyril Onwubiko, Director, Enterprise Security Architecture, Pearson Plc.  ...  Zhou Track 10: Emerging Nations & Risk Management Chapter 31 Adapting STPA-sec for Socio-technical Cyber Security Challenges in Emerging Nations: A Case Study in Risk Management for Rwandan HealthCare Joseph  ... 
doi:10.1109/cybersecurity49315.2020.9138868 fatcat:ag3ewuo7hvenlhm2we2pba5aea

A Theoretical Analysis of the Divergence Factors That Affect Students Academic Performance in University of Jos, Nigeria

Yusuf Izang Elijah, Audu Garba Tanko, Yusuf Izang Fatima
2020 International Journal of Innovative Research & Development  
for research Training and Development UK (www.eajournals.org) ISSN: ISSN 2059-1209, ISSN: ISSN 2059-1217, (accessed 17 th January, 2020), 40 11 Lannap, Basic Issues in Guidance…52 12 Interview with, Joseph  ...  They also indulged in these dirty lives to get good grades from lecturers, attention from the opposite sex, financial assistant, security and to oppress their fellow girlfriends. 32 Onwubiko and Okonkwo  ... 
doi:10.24940/ijird/2020/v9/i8/aug20021 fatcat:uler7uwshvdifiz6ojwwarc6i4

BULUT BİLİŞİM HİZMET SAĞLAYICILARININ VERİYİ KORUYAMAMALARI DURUMUYLA İLGİLİ TÜRK, AVRUPA BİRLİĞİ VE AMERİKAN HUKUKUNDAKİ DÜZENLEMELER

Kutan KORUYAN, Fatma Itır BİNGÖL
2016 Dokuz Eylül Üniversitesi Sosyal Bilimler Enstitüsü Dergisi  
KAYNAKLAR Armbrust, M., Fox, A., Griffith, R., Joseph, A. D., Katz, R. H., Konwinski, A. Lee, G., Patterson, D. A., Rabkin, A., Stoica, I. ve Zaharia, M. (2009).  ...  ülkede tutulduğunu ya da hangi ülkeye gönderildiğinden habersiz olduğu durumlarda, kullanıcıyı gizlilik konusundaki temel prensiplerin ve hukukî düzenlemelerin korumasından mahrum bırakabilmektedir (Onwubiko  ... 
doi:10.16953/deusbed.67150 fatcat:zcvwxwaorfdytme2dp5ga3o4ly
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