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The matrices C W R 1 and C W R 2 relate by C W R 1 = −1 0 0 0 −1 0 0 0 1 C W R 2 The corresponding optical centre locations are given by W C t 1 = − 1 λ C W R T 1 t 1 t 2 t 3 and W C t ... Let C W R 1 and C W R 2 be the two candidates for C W R, corresponding respectively to the scaling by + λ and − λ . ...doi:10.1016/s0921-8890(01)00120-8 fatcat:axgpnslrirhspatusjvwvvchlm
Part Coordinate Systems CS José V. Abellán-Nebot et al. / Procedia Manufacturing 41 (2019) 906-913Author name / Procedia Manufacturing 00 (2020) 000-000 ... F R C C F o R C C F o R C C F o R C C F o R C F R B B F o R B B F o R B B F o R B B F o R B F R B B F o R B B F o R B B F o R B B F o R B R F T F C o F T F C o T F B o ...doi:10.1016/j.promfg.2019.10.014 fatcat:su4njykowvgjxdxp6prr72o2n4
Trabajos Originales Sintomatología depresiva en el post parto y factores psicosociales asociados Daniela Romero R 1 a , Luz Adriana Orozco R 1 b , José Luis Ybarra S 1 c y Blanca Irene Gracia R 1d 1 Unidad ... Sí ___ No___ ¡GRACIAS POR SU PARTICIPACIÓN! Ficha: Fecha: I. FACTORES SOCIODEMOGRÁFICOS 1. Hospital dónde se atiende ______________ 2. Fecha de nacimiento del bebé ___________ 3. ...doi:10.4067/s0717-75262017000200009 fatcat:sqyhm23dd5cefon6b2evl75hze
Contralateral injection has been described as a useful tool in the treatment of chronic total occlusions (CTOs) to evaluate the distal segments of the occluded artery [1, 2] . This case shows that contralateral injections are feasible through just one puncture using a 6 Fr sheath, a long guidewire of 0.014" and a 5 Fr diagnosis catheter in parallel. We present a 64-year-old man with severe peripheral vasculopathy. Coronary angiography showed a chronic total occlusion at the left circumflexdoi:10.5114/pwki.2015.52291 pmid:26161110 pmcid:PMC4495134 fatcat:o3gdxiw4fjhqhegvse6n25siiu
more »... y and severe stenosis in the right coronary artery; circulation to the marginal branch was supplied from a posterolateral branch of the right coronary artery. Percutaneous coronaty intervention (PCI) was performed through a 6 Fr sheath placed in the right radial artery. We began the procedure treating the left circumflex artery occlusion with an EBU 3.5 6 Fr guiding catheter and an Asahi Sion "J" guidewire which crossed the occlusion easily. However, after dilatations with a 2.5 × 15 mm balloon, no distal filling was observed (Figure 1 A) . We changed the first angioplasty guidewire for a 0.014" 300 cm length BMW guidewire. We passed in parallel a regular wire (0.035" 260 cm J) inside the guide catheter until it reached the aortic root. Then, using the same sheath, we changed to a JR 5 Fr diagnosis catheter to perform a contralateral injection. The injection from the right coronary artery showed that the guidewire was placed successfully in the marginal branch (Figure 1 B) . After that we advanced the previous guiding catheter using again the regular guide in the aortic root while still maintaining the 0.014" BMW 300 cm in the marginal branch. Needing buddy-wire technique, a 2.5 × 33 mm everolimus drug-eluting stent was successfully deployed in the middle segment of the circumflex artery towards the marginal branch, and another similar 2.25 × 18 mm stent distally to the previous one (Figure 1 C) . Thereafter the collateral circulation to the marginal branch disappeared. This case shows that contralateral injections are feasible through a unique puncture site using a 6 Fr sheath, a long guidewire of 0.014" placed in the endpoint branch and a 5 Fr diagnosis catheter in parallel. The 0.035" 260 cm J regular wire placed in the aortic root helps to change catheters, improving the softness of the angioplasty guidewire (and avoiding its prolapse in the coronary artery). Recently there have been published reports of two different ways to perform bilateral angiography in a single radial access once the wires had crossed the CTO but it was uncertain whether the wires were in the true lumen. The first one, called BASIRALA (bilateral angiography in a single radial access) , uses a microcatheter to inject selectively in the donor branches connected with CTOs. The second one  involves injecting with the same multipurpose guiding catheter in which the operator creates a loop of the wire in the coronary sinus and ascending aorta. This looped wire allows the catheter to be turned towards the contralateral artery without disengagement of the wire. None of these three techniques can offer a real simultaneous contralateral injection. It is possible, simple and safe to perform contralateral injections using a parallel long angioplasty 0.014" guidewire and a diagnosis catheter one French smaller than the sheath. The use of one 0.035" 260 cm regular wire helps during catheter exchanges.
Grácia D. F. Silva, Silvia R. S. Silva, Luiz C. A. Barbosa, Lucienir P. Duarte, Sonia M. R. Ribeiro, José H. Queiroz et al. ... /Jun. 2009 Grácia D. F. Silva, Silvia R. S. Silva, Luiz C. A. Barbosa, Lucienir P. Duarte, Sonia M. R. Ribeiro, José H. Queiroz et al. Rev. Bras. Farmacogn. Braz. J. Pharmacogn. 19(2B): Abr. ...doi:10.1590/s0102-695x2009000400004 fatcat:qyrr7e7t2vbyhi7na4rc7bingu
Vibrio spp. is a pathogen rarely isolated in cancer patients, and in most cases it is associated with haematological diseases. Cutaneous manifestations of this organism are even rarer. We report a case of Non-O1 Vibrio cholerae inguinal skin and soft tissue infection presenting bullous skin lesions in a young type II diabetic patient with a penis squamous cell carcinoma having a seawater exposure history.doi:10.1186/1476-0711-8-17 pmid:19454006 pmcid:PMC2691727 fatcat:ssgiysbq6ndxdfnhxaxno5lp2q
MC, Chiapparino E, Bahri H, Salem BM, Forster BP, Ellis RP, Rhouma S, 11 Zoumarou W, Waugh R, Tuberosa R (2004) Identification of Hordeum spontaneum QTL 12 alleles improving field performance of barley ... J Agric Genomics (former J QTL), vol 1995 art 2. 16 http://probe.nalusda.gov:8000/ otherdocs/jqtl/jqtl1995-02. 17 Tohno-oka T, Ishit M, Kanatani R, Takahashi H, Takeda K (2000) Genetic analysis of photoperiod ... J R Stat Soc 57:289-300Blake TK, Kadyrzhanova D, Sheperd 4 KW et al (1996) Mogador allele. ...doi:10.1007/s11032-007-9145-3 fatcat:ijkj5lzw65anza34opuuwxme2i
2017 IEEE Power & Energy Society General Meeting
FigB.5 CONDUCTOR ELECTRICAL RESISTANCE high low avg avg low low high low ( ) ( ) ( ) ( ) ( ) R T R T R T T T R T TT (21) The impedance and ... B-7 1 2 (1 ) 1 42 s R s R YZ Z V V I I YZ YZ Y (22) SR SR 2( ) II Y VV (23) 22 SR S R R S VV ... conductor; T avg is the average conductor temperature; and R(T avg ) is AC resistance of conductor at temperature, T avg . ...doi:10.1109/pesgm.2017.8273743 fatcat:t73l7mwq3vc6pbutb22xgs6n6a
This paper draws together contributions to a scientific table discussion on obesity at the European Science Open Forum 2008 which took place in Barcelona, Spain. Socioeconomic dimensions of global obesity, including those factors promoting it, those surrounding the social perceptions of obesity and those related to integral public health solutions, are discussed. It argues that although scientific accounts of obesity point to large-scale changes in dietary and physical environments, mediadoi:10.1186/1744-8603-6-7 pmid:20416037 pmcid:PMC2873249 fatcat:rssvydsdfzbe7pwvjysdsnd5cu
more »... entations of obesity, which context public policy, pre-eminently follow individualistic models of explanation. While the debate at the forum brought together a diversity of views, all the contributors agreed that this was a global issue requiring an equally global response. Furthermore, an integrated ecological model of obesity proposes that to be effective, policy will need to address not only human health but also planetary health, and that therefore, public health and environmental policies coincide.
Neurodegenerative diseases present a current challenge for accurate diagnosis and for providing precise prognostic information. Developing imaging biomarkers for multiple sclerosis (MS), Parkinson disease (PD), and Alzheimer's disease (AD) will improve the clinical management of these patients and may be useful for monitoring treatment effectiveness. Recent research using optical coherence tomography (OCT) has demonstrated that parameters provided by this technology may be used as potentialdoi:10.1155/2016/8503859 pmid:27840739 pmcid:PMC5093273 fatcat:odjqlyh3fvemzchug72xygr5wi
more »... arkers for MS, PD, and AD. Retinal thinning has been observed in these patients and new segmentation software for the analysis of the different retinal layers may provide accurate information on disease progression and prognosis. In this review we analyze the application of retinal evaluation using OCT technology to provide better understanding of the possible role of the retinal layers thickness as biomarker for the detection of these neurodegenerative pathologies. Current OCT analysis of the retinal nerve fiber layer and, specially, the ganglion cell layer thickness may be considered as a good biomarker for disease diagnosis, severity, and progression.
α-Synuclein amyloid self-assembly is the hallmark of a number of neurodegenerative disorders, including Parkinson's disease, although there is still very limited understanding about the factors and mechanisms that trigger this process. Primary nucleation has been observed to be initiated in vitro at hydrophobic/hydrophilic interfaces by heterogeneous nucleation generating parallel β-sheet aggregates, although no such interfaces have yet been identified in vivo. In this work, we have discovereddoi:10.1101/2020.09.28.315325 fatcat:glyisavaybfg7gni7okkmjogay
more »... hat α-synuclein can self-assemble into amyloid aggregates by homogeneous nucleation, without the need of an active surface, and with a preference for an antiparallel β-sheet arrangement. This particular structure has been previously proposed to be distinctive of stable toxic oligomers and we here demonstrate that it indeed represents the most stable structure of the preferred amyloid pathway triggered by homogeneous nucleation under limited hydration conditions, including those encountered inside α-synuclein droplets generated by liquid-liquid phase separation. In addition, our results highlight the key role that water plays not only in modulating the transition free energy of amyloid nucleation, and thus governing the initiation of the process, but also in dictating the type of preferred primary nucleation and the type of amyloid polymorph generated depending on the extent of protein hydration. These findings are particularly relevant in the context of in vivo α-synuclein aggregation where the protein can encounter a variety of hydration conditions in different cellular microenvironments, including the vicinity of lipid membranes or the interior of membraneless compartments, which could lead to the formation of remarkably different amyloid polymorphs by either heterogeneous or homogeneous nucleation.
Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently identified the small GTPase Rab18 as a component of the LD coat. However, the specific contribution of Rab18 to adipocyte function remains to be elucidated. Herein, we have analyzed Rab18 expression, intracellular localization and function in relation to the metabolic statusdoi:10.1371/journal.pone.0022931 pmid:21829560 pmcid:PMC3145781 fatcat:rm5xf4mvinbmxpbpc2f2byprfy
more »... of adipocytes. We show that Rab18 production increases during adipogenic differentiation of 3T3-L1 cells. In addition, our data show that insulin induces, via phosphatidylinositol 3-kinase (PI3K), the recruitment of Rab18 to the surface of LDs. Furthermore, Rab18 overexpression increased basal lipogenesis and Rab18 silencing impaired the lipogenic response to insulin, thereby suggesting that this GTPase promotes fat accumulation in adipocytes. On the other hand, studies of the badrenergic receptor agonist isoproterenol confirmed and extended previous evidence for the participation of Rab18 in lipolysis. Together, our data support the view that Rab18 is a common mediator of lipolysis and lipogenesis and suggests that the endoplasmic reticulum (ER) is the link that enables Rab18 action on these two processes. Finally, we describe, for the first time, the presence of Rab18 in human adipose tissue, wherein the expression of this GTPase exhibits sex-and depot-specific differences and is correlated to obesity. Taken together, these findings indicate that Rab18 is involved in insulin-mediated lipogenesis, as well as in b-adrenergic-induced lipolysis, likely facilitating interaction of LDs with ER membranes and the exchange of lipids between these compartments. A role for Rab18 in the regulation of adipocyte biology under both normal and pathological conditions is proposed.
Obtenido de https://www.gob.mx/profeco/documentos/alimentos-organicos  Roldán, H., Gracia, M., Santana, M. & Horbath, J. (09 de junio de 2016). ... México ha sido parte de este proceso, en primer lugar, como exportador de productos, gracias a ello, el sector orgánico es uno de los más dinámicos del sector agrícola a pesar de que solo el 15 % de la ...doi:10.29057/esat.v8i16.7430 fatcat:y4n7lhru65bmdj3g6gpvlx2mbe
AbstractObjectiveHealthy lifestyle habits are the cornerstone in the management of familial hypercholesterolaemia (FH). Nevertheless, dietary studies on FH-affected populations are scarce. The present study analyses dietary habits, adherence to a Mediterranean diet pattern and physical activity in an adult population with FH and compares them with their non-affected relatives.DesignCross-sectional study.SettingData came from SAFEHEART, a nationwide study in Spain.ParticipantsIndividuals (ndoi:10.1017/s1368980018003853 pmid:30732662 fatcat:7xysfkzmw5erljrtloigxte4ga
more »... aged ≥18 years with a genetic diagnosis of FH (n2736) and their non-affected relatives (n 978). Food consumption was evaluated using a validated FFQ.ResultsTotal energy intake was lower in FH patients v. non-affected relatives (P<0·005). Percentage of energy from fats was also lower in the FH population (35 % in men, 36 % in women) v. those non-affected (38 % in both sexes, P<0·005), due to the lower consumption of saturated fats (12·1 % in FH patients, 13·2 % in non-affected, P<0·005). Consumption of sugars was lower in FH patients v. non-affected relatives (P<0·05). Consumption of vegetables, fish and skimmed milk was higher in the FH population (P<0·005). Patients with FH showed greater adherence to a Mediterranean diet pattern v. non-affected relatives (P<0·005). Active smoking was lower and moderate physical activity was higher in people with FH, especially women (P<0·005).ConclusionsAdult patients with FH report healthier lifestyles than their non-affected family members. They eat a healthier diet, perform more physical activity and smoke less. However, this patient group's consumption of saturated fats and sugars still exceeds guidelines.
José R. ... Félix Gutiérrez, José R. Arribas, Pere Domingo, José A. Iribarren, José López-Aldeguer, Fernando Lozano, Esteban Martínez, Eugenia Negredo, María J. ...doi:10.3265/nefrologia.pre2014.jul.12674 pmid:25467377 fatcat:qkhfuj4275eifeu3w3wsxf2jva
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