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2019
San Antonio Review
Jamie L. ...
Smith is an MFA candidate in Creative Writing at Hunter College, where she has been the recipient of the Colie Hoffman Poetry Prize and the 2019 Guggenheimer Award, and was runner up for the Academy of ...
doi:10.21428/9b43cd98.4a06cf7a
fatcat:2wktrswpjne6lk7p4sqfnug5sq
Critiquing Protein Family Classification Models Using Sufficient Input Subsets
[article]
2019
bioRxiv
pre-print
S Q D L T 43 S T E K R D A Q N L G V 44 K E L R Q A S 45 E Q K S A D N R T H L V 46 E D Q A K S T R H N 47 C A S G T V L I P N R K F E D Q Y M 48 E K Q R S A N L T D M 49 S K E A R N Q D T G 50 L A V ...
S A D E K Q R T N L V H P I Y M F W 109 110 D 111 C G I A V S L 112 I V L C F K M Y 113 V L I F 114 L I V C M F 115 V I L M C F T K E A S Q R N D G H P Y W 116 V I A L T G C K E S Q R N D H M P Y F W ...
doi:10.1101/674119
fatcat:zlavnjh43zfi3nrworta36azpe
Impact of Environmental Justice on Transportation
2012
Transportation Research Record
Smith, Stefanie R. Brodie, Jamie M. Fischer, and Catherine L. Ross Presidential Executive Order 12898 on Environmental Justice (EJ) was signed in 1994, and the U.S. ...
doi:10.3141/2320-01
fatcat:w5e332mvencqzf5veyop2jskgi
Chronic Rhinosinusitis, Race, and Ethnicity
2012
American Journal of Rhinology & Allergy
The study by Smith et al. in 2010 did report the racial and ethnic makeup of study participants, with 35 of 302 patients from a minority group. 18 However, subgroup analysis according to race/ethnicity ...
Race/ethnicity data in studies reporting efficacy outcomes after surgery in patients with CRS Study
Year
Location
Practice
Design
Outcome
Size
(n)
Race/Ethnicity
Reported
Minority
(n)
Smith ...
doi:10.2500/ajra.2012.26.3741
pmid:22487286
pmcid:PMC3345896
fatcat:6mbfjdoth5b3jmuntgoybsrqaq
Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway
2010
Structure
Modular PKS systems are thought to share a common ancestor with mammalian fatty acid synthases (mFAS) (Smith and Sherman, 2008) . ...
L A A A S L T FA ---A TE CQ I E D I L F TA K N L HP L L GE K L N L A R I E NQHH FQS Y L TA E S P A Y L S QHQV FNK V L FP A TGY L E I A A A V GK N L L --T TGE QV V V S DV QS L V I P E -TE I K TV Q TV V ...
doi:10.1016/j.str.2009.10.018
pmid:20152156
pmcid:PMC3102235
fatcat:b5eosibrbfeulbbgeomgr3y3se
Allopregnanolone mediates affective switching through modulation of oscillatory states in the basolateral amygdala
[article]
2021
bioRxiv
pre-print
Number of Entries in c, center; f, lit area; i, open arms. l, Summary of average absolute time difference in allo vs vehicle infused conditions across behavioral tests. Error bars represent SEM. ...
Schematics for behavioral tests and associated phenotypes in Wt mice infused with vehicle or 5 µg (2.5 µg/µl -inject) Allo: a, open field; d, light dark box; g, elevated plus maze, j, Tail suspension test ...
doi:10.1101/2021.03.08.434156
fatcat:5p2so2hlvbe65bmtssjnbczvfu
Project management for the 21st century
2005
Proceedings of the 43rd annual southeast regional conference on - ACM-SE 43
Managing software project teams is a complex task further complicated by a continued increase in the size and complexity of software-intensive systems and the distribution of project teams. Given limited project resources, distributed teams require appropriate team processes and adequate tool support to help them remain focused on the most critical design tasks, thereby structuring the design process and improving team coordination. However, existing project management tools typically fall
doi:10.1145/1167253.1167319
dblp:conf/ACMse/SmithBM05
fatcat:4ue7bwom5fexlpz72wxzw6ozoe
more »
... . Software project management as a discipline is not unlike humancomputer interaction (HCI) in that both combine technical concerns with human psychological concerns. Both could benefit from a more systematic approach to applying theory to practice. One proposed approach to the science of design involves constructing a record of design rationale by leveraging design knowledge from previous projects. Extending the reuse paradigm from product-related knowledge to process-related knowledge could improve software project management by helping teams to externalize and maintain a physical record of their design process. A risk management model could help teams to prioritize design knowledge, allowing them to focus their effort on key design tasks.
Predictors of Olfactory Dysfunction in Patients With Chronic Rhinosinusitis
2008
The Laryngoscope
Objectives-To measure the prevalence of and identify clinical characteristics associated with poor olfactory function in a large cohort of patients with chronic rhinosinusitis (CRS). Study Design-Multi-institutional, cross sectional analysis. Methods-An objective measure of olfactory dysfunction, the Smell Identification Test (SIT), demographic data, clinical factors and co-morbidity data were collected from a cohort of 367 patients who presented with CRS at three tertiary care centers. Data
doi:10.1097/mlg.0b013e318184e216
pmid:19029858
pmcid:PMC2652888
fatcat:q6t4gawncffa5eq6wk32jvbzry
more »
... analyzed using univariate and multivariate analyses. Results-Sixty-four percent of men and women aged 18 to 64 had olfactory dysfunction whereas 95% of patients ≥ 65 years had olfactory dysfunction (p<0.001); no significant difference was noted by gender. By multivariate logistic regression analysis, patients with nasal polyposis (OR 2.4, 95% confidence interval (CI) 1.3, 4.2; p=0.003) and patients ≥ 65 years (OR 10.0, 95% CI 2.3, 43.7; p=0.002) were at increased risk of hyposmia. Patients with nasal polyposis (OR 13.2, 95% CI 5.7, 30.7; p<0.001), asthma (OR 4.2, 95% CI 1.8, 9.8; p=0.001), ≥ 65 years (OR 15.6, 95% CI 2.3, 104.9; p=0.005), and smokers (OR 7.6, 95% CI 1.8, 31.6; p=0.005) were at increased risk of anosmia. Conclusions-Poor olfactory function is common in patients with CRS. Age, nasal polyposis, smoking, and asthma were significantly associated with olfactory dysfunction in patients with CRS. Neither prior endoscopic sinus surgery nor a history of allergic rhinitis was associated with olfactory dysfunction. Septal deviation and inferior turbinate hypertrophy were associated with normal olfactory function.
Left ventricular assist device implantation strategies and outcomes
2015
Journal of Thoracic Disease
Over the past 15 years, the field of mechanical circulatory support has developed significantly. Currently, there are a multitude of options for both short and long term cardiac support. Choosing the appropriate device for each patient depends on the amount of support needed and the goals of care. This article focuses on long term, implantable devices for both bridge to transplantation and destination therapy indications. Implantation strategies, including the appropriate concomitant surgeries
doi:10.3978/j.issn.2072-1439.2015.08.13
pmid:26793328
pmcid:PMC4703687
fatcat:t4nkwkelbzbahd2icpg5ezydwq
more »
... re discussed as well as expected long term outcomes. As device technology continues to improve, long term mechanical circulatory support may become a viable alternative to transplantation.
Olfactory Function and Disease Severity in Chronic Rhinosinusitis
2009
American Journal of Rhinology & Allergy
Background-Olfactory dysfunction is deemed to be a significant contributor to poor quality of life (QOL). However, little is known about the relationship of olfactory testing to other measures of disease burden in patients with chronic rhinosinusitis (CRS). Objective-In this study, we examine the relationship of olfactory function to computed tomography (CT) scores, endoscopy scores, and QOL measures in patients with CRS. Methods-A multi-institutional, cross-sectional analysis of 367 patients
doi:10.2500/ajra.2009.23.3286
pmid:19401037
pmcid:PMC2676063
fatcat:e2xptco5hfdjxexqey3kzflsyu
more »
... s performed. Several objective measures were collected: the Smell Identification Test, Lund-MacKay CT score, Lund-Kennedy endoscopy score, two validated disease-specific QOL instruments, the Rhinosinusitis Disability Index and the Chronic Sinusitis Survey, and a general health-related QOL instrument, the Medical Short Form-36. Analysis of variance was performed. Correlation coefficients were calculated. Results-Patients with olfactory dysfunction had significantly worse mean endoscopy scores (normosmics: 4.16 (± 3.97); hyposmics: 6.26 (± 4.21); anosmics: 9.61 (± 4.48); p<0.001) and significantly worse CT scores (normosmics: 9.11 (± 5.40); hyposmics: 11.16 (± 5.96); anosmics: 17.62 (± 5.37); p<0.001). Endoscopy scores were moderately correlated with olfactory scores (r= -0.46, 95% CI -0.38, -0.54; p<0.001). CT scores were moderately correlated with olfactory scores (r= -0.53, 95% CI -0.45, -0.60; p<0.001). Olfactory function was not correlated with disease-specific or general health-related QOL measures. Conclusions-Although previous studies have suggested that olfactory impairment is associated with poor QOL, this study found no such correlation. In contrast, olfaction scores correlated well with other objective measures of CRS, namely endoscopy and CT scores.
Hybrid Instantaneous Wave-Free Ratio–Fractional Flow Reserve versus Fractional Flow Reserve in the Real World
2017
Frontiers in Cardiovascular Medicine
Copyright © 2017 Shuttleworth, Smith, Watt, Smith and Leslie. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). ...
doi:10.3389/fcvm.2017.00035
pmid:28612008
pmcid:PMC5447668
fatcat:xkw63opjgza45gw37jh4vew6xa
Synaptic resilience is associated with maintained cognition during ageing
[article]
2022
medRxiv
pre-print
Pellets were reconstituted and homogenised with 450μL buffer. Protein quantification was carried out using the micro Bicinchoninic acid assay (Pierce, UK). ...
Supplementary Fig. 3D-J ) namely, Related Ras small GTPase (RRAS); Inositol 1,4,5trisphosphate (ITPR1), Glutamate decarboxylase 2 (GAD2); Synaptosomal-Associated Protein, 25kDa (SNAP-25), Transmembrane 4 L ...
doi:10.1101/2022.05.04.22274679
fatcat:cfv3wwgderfshazvz6nehtvdxq
A Metabolomics Approach for Early Prediction of Vincristine-Induced Peripheral Neuropathy
[article]
2019
medRxiv
pre-print
Metabolomics sample preparation and extraction Protein removal and sample extraction were performed by adding 200 µL methanol to 100 µL of plasma. ...
Source parameters were as follows: nitrogen gas temperature = 330 • C and flow rate = 10 L/min, nebulizer pressure = 35 psi, sheath gas temperature = 250 • C, sheath gas flow rate = 7 L/min, and capillary ...
doi:10.1101/19013078
fatcat:umv6qgevdrautmzl33xd6vywlu
Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators
2016
eLife
This solution was warmed to 573 37 o C and 20 µl was delivered subcutaneously via the cannula into the electrically defined 574 innervation area. ...
be detected in many large diameter DRG 198 neurons during dorsal root stimulation at 100 Hz (ex vivo preparations) or in spindle afferents 199 during maintained muscle stretch (in vivo preparations; Smith-Edwards ...
doi:10.7554/elife.20527
pmid:27805567
pmcid:PMC5117853
fatcat:6i4arh354rewvo4mmma3vtsg5a
Does olfactory function improve after endoscopic sinus surgery?
2009
Otolaryngology and head and neck surgery
All patients had a diagnosis of CRS based on Correspondence to: Timothy L. Smith. ...
This publication was made possible with support from NIH/NIDCD R01 DC005805 (PI: TL Smith) and the Oregon Clinical and Translational Research Institute (OCTRI), grant number UL1 RR024140 from the National ...
doi:10.1016/j.otohns.2008.12.006
pmid:19248934
pmcid:PMC2668517
fatcat:wn6yvn2orrgq3ltosekbywdoba
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