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Analytic Platforms in Cruising Aircraft

1967 Journal of Aircraft  
AIRCRAFT VOL. 4, NO. 1 Analytic Platforms in Cruising Aircraft JAMES L. FARRELL* Westinghouse Electric Corporation, Baltimore, Md.  ...  L. FARRELL vectors, respectively.  ... 
doi:10.2514/3.59296 fatcat:x6ifuatkc5hl3hlz4g4u5lju3i

The Dividend Discount Model: A Primer

James L. Farrell
1985 Financial analysts journal  
by James L. Farrell, Jr. The Dividend Discount Model: A Primer The dividend discount model provides a means of developing an explicit expected return for the stock market.  ...  Farrell, Guide to Portfolio Management (New York: 5% Inflation Zero 100% 50% Zero Infla-Adjust-Adjust-Adjust- Stock tion ment mrent meint Dividend 1.00 1.02 1.01 1.00 Growth Rate 0.05  ... 
doi:10.2469/faj.v41.n6.16 fatcat:5eqrlz267jfi3gbvkmasvkdhxm

Diagnosis of Parathyroid Adenomas with New Ultrasound Imaging Modalities

Ghobad Azizi, Michelle L. Mayo, James Keller, Jessica Farrell, Carl Malchoff
2019 VideoEndocrinology  
Ultrasound technology is becoming an integral part of diagnosing parathyroid adenomas. Careful ultrasound evaluation with b-mode, shear wave elastography, and three-dimensional (3D) of parathyroid adenomas may improve localization and outcome. Introduction: A 60-year-old woman was referred for the evaluation of hyperparathyroidism. This patient gave her informed consent. She had a history of hypothyroidism and thyroid nodules. She was being treated with levothyroxine 50 mcg daily. Routine
more » ... g revealed hypercalcemia. The serum calcium was 11.2 (nL range 8.7-10.2 mg/dL), creatinine was 0.69 (nL range 0.57-1.00 mg/dL), intact parathyroid hormone (PTH) was 70 (nL range 15-65 pg/mL), phosphorus was 2.7 (nL range 2.5-4.5 mg/dL), vitamin D was 38.7 (30-100 ng/mL), and 24 hours urine calcium was 362.9 (100-300 mg/24 hour). The neck ultrasound showed two lesions one superior/posterior and the other in the inferior/posterior aspect of the right thyroid lobe measuring 11.6 × 4.4 × 9.7 mm and 14.6 × 5.0 × 10.0 mm, respectively. Both lesions resembled parathyroid adenomas. Shear wave velocity (SWV) measurements for the superior and inferior lesions were 1.67 and 1.77 m/second, respectively. For the adjacent thyroid tissue SWV was 2.3 m/second, significantly higher. 3D ultrasound examination demonstrated a polar artery in both lesions. A sestamibi scan showed a probable right parathyroid adenoma and she was referred for surgery. She was found to have two right parathyroid adenomas in the superior and inferior poles corresponding with the ultrasound finding. Intraoperative PTH level decreased from 139.9 to 17 pg/mL postresection. Six weeks after surgery, her calcium and PTH were normal. Materials and Methods: This patient was evaluated in our clinic with ultrasound imaging, including b-mode, shear wave elastography (SWE), and 3D ultrasound. Discussion: Most patients with primary hyperparathyroidism have a single parathyroid adenoma. Other causes include glandular hyperplasia, multiple adenomas, and parathyroid carcinoma.1,2 This case shows two parathyroid adenomas in the neck posterior to the right thyroid lobe. The role of ultrasound in diagnosing parathyroid adenomas is becoming more prominent because of improved technology, low cost, and noninvasive nature. With this case we illustrate that SWE can be an added value to b-mode ultrasound in diagnosing parathyroid adenomas. Our previous publication in the Journal of European Radiology reported that SWV measurement of parathyroid adenomas may enhance other sonographic parameters to predict the diagnosis. In our view, parathyroid adenomas appear to have a more homogenous texture and lower tissue stiffness when compared with the thyroid gland.3 This case confirms our prior findings. It can be challenging to differentiate parathyroid adenomas from lymph nodes (LNs) and ectopic thyroid tissue at level 6, with b-mode ultrasound. A combination of 3D ultrasound images with 3D color Doppler (CD) might improve our ability to identify the polar artery and enhance differentiation from LN. 3D technology might improve the view by adding coronal view to current b-mode that comprises of transverse and longitudinal views. This is a preliminary report, and more studies need to be done. Conclusion: Combining multiple image modalities, including b-mode, shear wave elastography, and 3D technology, may improve our ability to identify parathyroid adenomas. Parathyroid adenomas have a lower SWV compared with thyroid tissue. 3D ultrasound technology may enhance view of polar artery when adding 3D CD. This challenging case illustrates the utility of these additional modalities. No competing financial interests exist. Runtime of video: 1 min, 52 secs.
doi:10.1089/ve.2019.0163 pmid:32025531 pmcid:PMC6961788 fatcat:clg63owrdfd43fqhdplsghkdh4

Analyzing Covariation of Returns to Determine Homogeneous Stock Groupings

James L. Farrell, Jr.
1974 The journal of business  
James L.  ...  Farrell, Jr.* Analyzing Covariation of Returns to Determine Homogeneous Stock Groupings} lL INTRODUCTION Cohen and Pogue’s empirical evaluation of the multi-index and single- index portfolio selection  ... 
doi:10.1086/295630 fatcat:3ckgjnxsgffrvopzyzgu3upsse

Analysis of the circular RNA transcriptome in endometrial cancer

Bei Jun Chen, Frances L. Byrne, Konii Takenaka, Susan C. Modesitt, Ellen M. Olzomer, James D. Mills, Rhonda Farrell, Kyle L. Hoehn, Michael Janitz
2017 OncoTarget  
Circular RNAs (circRNAs) are a naturally occurring family of non-coding RNA that may regulate gene expression in mammals. circRNAs are more stable than messenger RNAs due to their resistance to RNA exonuclease. A growing body of evidence has shown that the expression of circRNAs is regulated during development in a tissuespecific manner. CircRNAs have been implicated in a number of cancers; however, their role in endometrial cancer (EC) is completely unknown. Here, we report the circular
more » ... iptome specific for EC as determined by RNA sequencing. We found that the overall abundance of circRNAs is lower in EC than in normal endometrium. Further, there are numerous 'hotspot' genes from which circRNAs are transcribed that may account for alterations in circRNA expression between the normal and malignant endometrium. Most importantly, we have also identified circRNAs that are differentially expressed between malignant and normal endometrial tissue. The functional significance of these circRNAs in cancer remains to be determined, but they may serve as potential biomarkers for the diagnosis of EC or monitoring of EC progression.
doi:10.18632/oncotarget.23534 pmid:29464034 pmcid:PMC5814174 fatcat:wjwrjamq5zdhnbprm4vd2tkxju

Optimum Vegetation Conditions for Successful Establishment of Planted Eastern White Pine (Pinus strobus L.)

Douglas Pitt, Michael Hoepting, William Parker, Andrée Morneault, Len Lanteigne, Al Stinson, James Farrell
2016 Forests  
The 10th-growing season performance of planted eastern white pine (Pinus strobus L.) seedlings was evaluated in response to herbaceous and woody vegetation control treatments within a clearcut and two  ...  (Diervilla lonicera Mill.), and a variety of forbs, dominated by spreading dogbane (Apocynum androsaemifolium L.), large-leaved aster (Aster macrophyllus L.) and wild sarsaparilla (Aralia nudicaulis L  ...  (Diervilla lonicera Mill.), and a variety of forbs, dominated by spreading dogbane (Apocynum androsaemifolium L.), large-leaved aster (Aster macrophyllus L.) and wild sarsaparilla (Aralia nudicaulis L  ... 
doi:10.3390/f7080175 fatcat:dnm3u2652bep3pyaddskuavxjq

Advancing Workplace Health Protection and Promotion for an Aging Workforce

Ronald R. Loeppke, Anita L. Schill, L. Casey Chosewood, James W. Grosch, Pamela Allweiss, Wayne N. Burton, Janet L. Barnes-Farrell, Ron Z. Goetzel, LuAnn Heinen, T. Warner Hudson, Pamela Hymel, James Merchant (+3 others)
2013 Journal of Occupational and Environmental Medicine  
Objective: To explore issues related to the aging workforce, including barriers to integrating health protection and promotion programs, and provide recommendations for best practices to maximize contributions by aging workers. Methods: Workgroups reviewed literature and case studies to develop consensus statements and recommendations for a national approach to issues related to older workers. Results: Consensus statements and actions steps were identified for each of the Summit goals and
more » ... o-action statements were developed. Conclusions: A national dialogue to build awareness of integrated health protection and promotion for the aging workforce is needed. Workers will benefit from improved health and performance; employers will realize a more engaged and productive workforce; and the nation will gain a vital, competitive workforce. T he workforce of the twenty-first century is aging, with increasingly larger proportions of the workforce 55 years of age and older. This development is the result of a convergence of demographic and societal trends. First, the global population is aging. By 2018, people aged 65 years and older are expected to outnumber
doi:10.1097/jom.0b013e31829613a4 pmid:23657074 fatcat:cprjhlyegfafrmjmigwzr2yfyu

The mechanism of oxide ion conductivity in bismuth rhenium oxide, Bi28Re2O49

Julia L. Payne, James D. Farrell, Alistair M. Linsell, Mark R. Johnson, Ivana Radosavljević Evans
2013 Solid State Ionics  
Ivana R (2013) 'The mechanism of oxide ion conductivity in bismuth rhenium oxide, Bi28Re2O49.', Solid state ionics., 244 . pp. 35-39. Further information on publisher's website: The full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that: • a full bibliographic reference is made to the original source • a link is made to the metadata record
more » ... in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders. Please consult the full DRO policy for further details. Abstract We have carried out a combined experimental and computational study of oxide ion conductor Bi 28 Re 2 O 49 , with the aim of elucidating the conductivity mechanisms and pathways in this material. Single crystals of Bi 28 Re 2 O 49 were grown from melt and the structure investigated for the first time by single crystal X-ray diffraction. The structural model obtained is consistent with the Re atoms in Bi 28 Re 2 O 49 being both four-and six-coordinate, in a 3:1 ratio, in agreement with previous EXAFS and IR spectroscopy studies. The thermal displacement parameters of the oxygen atoms bonded to Re suggest substantial disorder of the Re coordination polyhedra. Ab-initio molecular dynamics simulations were performed to probe the oxide ion migration pathways in Bi 28 Re 2 O 49 and the roles of the Bi-O and Re-O sublattices. The key conclusion is that the ability of Re to support variable coordination environments is vitally important in Bi 28 Re 2 O 49 ; it provides a mechanism for 'self-doping' of the structure, i.e. the creation of O 2vacancies in the fluorite-like Bi-O sublattice by exchange of O atoms with the Re-O sublattice, and the subsequent increase of the average coordination number of Re. All three crystallographically unique oxygen sites in the Bi-O sublattice play roles in the ionic migration processes, by facilitating the O 2exchange between the ReO x groups and by contributing to the O 2diffusion via the vacancy-hopping mechanisms.
doi:10.1016/j.ssi.2013.05.004 fatcat:qtqb27tl7zc53agtfvkqqi5x2e

Servants, scoundrels, and hitchhikers: current understanding of the complex interactions between crayfish and their ectosymbiotic worms (Branchiobdellida)

James Skelton, Kaitlin J. Farrell, Robert P. Creed, Bronwyn W. Williams, Catlin Ames, Brian S. Helms, James Stoekel, Bryan L. Brown
2013 Freshwater Science  
Conversely, introduction of just 1 worm initiated strong and directed grooming behaviors in O. cristavarius (Farrell et al.  ...  (Lee et al. 2009 , Brown et al. 2012 ) and context-dependent (Lee et al. 2009 ) effects of cleaners on their hosts, and complex species-specific control behaviors that may limit overexploitation (Farrell  ... 
doi:10.1899/12-198.1 fatcat:ld5k3or6kbgn7akpxthvkrcosq

Effect of silicic acid on arsenate and arsenite retention mechanisms on 6-L ferrihydrite: A spectroscopic and batch adsorption approach

Xiaodong Gao, Robert A. Root, James Farrell, Wendell Ela, Jon Chorover
2013 Applied Geochemistry  
Batch sorption results indicate that the adsorption of arsenate and arsenite on the 6-L ferrihydrite surface exhibits a strong pH-dependence, and the effect of pH on arsenic sorption differs between arsenate  ...  The EXAFS data indicate that arsenite forms both mononuclear bidentate and binuclear bidentate complexes with 6-L ferrihydrite as indicated by two As(III)-Fe bond distances of ~2.92-2.94 and 3.41-3.44  ...  The Ge IRE in the flow cell was coated with a thin layer of 6-L ferrihydrite by evenly depositing 500 μL nanoparticulate ferrihydrite suspension on the IRE surface.  ... 
doi:10.1016/j.apgeochem.2013.09.005 pmid:25382933 pmcid:PMC4223807 fatcat:tyfddnbzrzeuvonb3fey3fd7xy

Endoscopic ultrasound (EUS) and the management of pancreatic cancer

Muhammad Nadeem Yousaf, Fizah S Chaudhary, Amrat Ehsan, Alejandro L Suarez, Thiruvengadam Muniraj, Priya Jamidar, Harry R Aslanian, James J Farrell
2020 BMJ Open Gastroenterology  
Pancreatic cancer is one of the leading causes of cancer-related mortality in western countries. Early diagnosis of pancreatic cancers plays a key role in the management by identification of patients who are surgical candidates. The advancement in the radiological imaging and interventional endoscopy (including endoscopic ultrasound (EUS), endoscopic retrograde cholangiopancreatography and endoscopic enteral stenting techniques) has a significant impact in the diagnostic evaluation, staging and
more » ... treatment of pancreatic cancer. The multidisciplinary involvement of radiology, gastroenterology, medical oncology and surgical oncology is central to the management of patients with pancreatic cancers. This review aims to highlight the diagnostic and therapeutic role of EUS in the management of patients with pancreatic malignancy, especially pancreatic ductal adenocarcinoma.
doi:10.1136/bmjgast-2020-000408 pmid:32414753 fatcat:je5vcrdfejhh7c5nsd2oykx4ti

Time Series Adjustment Enhancement of Hierarchical Modeling of Arabidopsis Thaliana Gene Interactions [chapter]

Edward E. Allen, John Farrell, Alexandria F. Harkey, David J. John, Gloria Muday, James L. Norris, Bo Wu
2020 Lecture Notes in Computer Science  
John Farrell thanks Wake Forest University for support as a Wake Forest Fellow for Summer 2019.  ...  1 ) and σ 2 c ∼ Inverse-gamma(v o /2, v o σ 2 o /2).With these assumptions, we have the following result that gives the mathematical and statistical computation of the Norris-Patton likelihood (NPL), L  ...  With L = f (y 1 , . . . , y n |D) the NPL of data y 1 , . . . , y n , and χ D (e) = 1 if e is a directed edge in DAG D and χ D (e) = 0 otherwise, the posterior probability of an edge e is computed by the  ... 
doi:10.1007/978-3-030-42266-0_11 fatcat:aumo36oecnagxcrjzjaw3sylpm

Individual and work factors related to perceived work ability and labor force outcomes

Alyssa K. McGonagle, Gwenith G. Fisher, Janet L. Barnes-Farrell, James W. Grosch
2015 Journal of Applied Psychology  
., repetitive motions or twisting the body) may also invoke concerns about the effects of such exposures on the continued ability to work in such conditions (Barnes-Farrell et al., 2004; Fischer et al  ...  The retirement literature indicates that workers may choose to retire from work as a result of either "push" factors, "pull" factors, or a combination of both (Barnes-Farrell, 2003; Shultz et al., 1998  ... 
doi:10.1037/a0037974 pmid:25314364 pmcid:PMC4879965 fatcat:oxyhxfzzpbeu3cd4i7geaijose

Muskellunge and Northern Pike Ecology and Management: Important Issues and Research Needs

Derek P. Crane, Loren M. Miller, James S. Diana, John M. Casselman, John M. Farrell, Kevin L. Kapuscinski, Joe K. Nohner
2015 Fisheries  
L∞ represents the asymptotic length from the von Bertalanffy growth equation. Data, analyses, and figure provided by author John Casselman.  ...  Farrell (2001) found that Northern Pike in the St.  ... 
doi:10.1080/03632415.2015.1038382 fatcat:6535gsqpyvdondme5sgfthoive

The impact of community-wide, mass drug administration on aggregation of soil-transmitted helminth infection in human host populations

Marleen Werkman, James E. Wright, James E. Truscott, William E. Oswald, Katherine E. Halliday, Marina Papaiakovou, Sam H. Farrell, Rachel L. Pullan, Roy M. Anderson
2020 Parasites & Vectors  
Soil-transmitted helminths (STH) are intestinal parasites estimated to infect over 1.5 billion people. Current treatment programmes are aimed at morbidity control through school-based deworming programmes (targeting school-aged children, SAC) and treating women of reproductive age (WRA), as these two groups are believed to record the highest morbidity. More recently, however, the potential for interrupting transmission by treating entire communities has been receiving greater emphasis and the
more » ... asibility of such programmes are now under investigation in randomised clinical trials through the Bill & Melinda Gates Foundation funded DeWorm3 studies. Helminth parasites are known to be highly aggregated within human populations, with a small minority of individuals harbouring most worms. Empirical evidence from the TUMIKIA project in Kenya suggests that aggregation may increase significantly after anthelminthic treatment. A stochastic, age-structured, individual-based simulation model of parasite transmission is employed to better understand the factors that might induce this pattern. A simple probabilistic model based on compounded negative binomial distributions caused by age-dependencies in both treatment coverage and exposure to infection is also employed to further this understanding. Both approaches confirm helminth aggregation is likely to increase post-mass drug administration as measured by a decrease in the value of the negative binomial aggregation parameter, k. Simple analytical models of distribution compounding describe the observed patterns well. The helminth aggregation that was observed in the field was replicated with our stochastic individual-based model. Further work is required to generalise the probabilistic model to take account of the respective sensitivities of different diagnostics on the presence or absence of infection.
doi:10.1186/s13071-020-04149-4 pmid:32513254 fatcat:5dxudwjq4fgplfoawstx55bf2e
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