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Australian Schizophrenia Research Bank: a database of comprehensive clinical, endophenotypic and genetic data for aetiological studies of schizophrenia
2010
Australian and New Zealand journal of psychiatry (Print)
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This article describes the establishment of the Australian Schizophrenia Research Bank (ASRB), which operates to collect, store and distribute linked clinical, cognitive, neuroimaging and genetic data ...
The ASRB is a valuable and accessible schizophrenia research facility for use by approved scientific investigators. ...
Declaration of interest : The Australian Schizophrenia ...
doi:10.3109/00048674.2010.501758
pmid:21034186
fatcat:beqlvu6jmvdarifxybcs4ggd7q
The Importance of Brain Banks for Molecular Neuropathological Research: The New South Wales Tissue Resource Centre Experience
2009
International Journal of Molecular Sciences
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The focus of this tissue collection is on schizophrenia and allied disorders, alcohol use disorders and controls. ...
The New South Wales Tissue Resource Centre (TRC) at The University of Sydney has grown from a small tissue collection into one of the leading international brain banking facilities, which operates with ...
The Australian Brain Donor Programs NSW Tissue Resource Centre is supported by The University of Sydney, National Health and Medical Research Council of Australia, Schizophrenia Research Institute, National ...
doi:10.3390/ijms10010366
pmid:19333451
pmcid:PMC2662458
fatcat:hlecpmgaencexk7cbtznhh27i4
Association of NOS1AP variants and depression phenotypes in schizophrenia
2015
Journal of Affective Disorders
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The nitric oxide synthase 1 adaptor protein gene (NOS1AP) has previously been recognised as a schizophrenia susceptibility gene due to its role in glutamate neurotransmission. ...
Methods: Nine NOS1AP SNPs, rs1415259, rs1415263, rs1858232, rs386231, rs4531275, rs4656355, rs4657178, rs6683968 and rs6704393 were genotyped in 235 schizophrenia subjects screened for various phenotypes ...
Acknowledgements This study was supported by a Post-graduate Research Award scholarship provided by the Queensland University of Technology, and the Australian Schizophrenia Research Bank (ASRB), which ...
doi:10.1016/j.jad.2015.08.069
pmid:26384012
fatcat:dhku5p4idrdjbcoxviavtr77me
Reduced integrity of the left arcuate fasciculus is specifically associated with auditory verbal hallucinations in schizophrenia
2015
Schizophrenia Research
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Method: Diffusion tensor imaging scans and clinical data were obtained from the Australian Schizophrenia Research Bank for 39 schizophrenia patients with lifetime AVH (18 current, 21 remitted), 74 schizophrenia ...
Evidence was found for a non-linear relation between fractional anisotropy in the AF L and state AVH. ...
This study was supported by the Schizophrenia Research Institute using data from the Australian Schizophrenia Research Bank, funded by NHMRC Enabling Grant (No. 386500) held by V Carr, U Schall, R Scott ...
doi:10.1016/j.schres.2014.12.041
pmid:25631452
fatcat:aoxq55dvnjazhhn2i2n5ocxeym
Dysbindin (DTNBP1) variants are associated with hallucinations in schizophrenia
2015
European psychiatry
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The gene is known to be associated with cognitive deficit phenotypes within schizophrenia. ...
Methods: Five DTNBP1 SNPs, rs17470454, rs1997679, rs4236167, rs9370822 and rs9370823 were genotyped in 235 schizophrenia subjects screened for various phenotypes in the domains of depression, mania, hallucinations ...
Acknowledgements This study was supported by the Post-graduate Research Award scholarship provided by the Queensland University of Technology, and the Australian Schizophrenia Research Bank (ASRB), which ...
doi:10.1016/j.eurpsy.2015.01.008
pmid:25697573
fatcat:bsdk6bvuoza4lotrwqbv3jrp4a
Brain donation for schizophrenia research: gift, consent, and meaning
2003
Journal of Medical Ethics
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research into schizophrenia. ...
Organ donation for purposes of research differs from transplant donation in a number of ways, most notably the absence of a single recipient. ...
their brain when they die for research into schizophrenia. ...
doi:10.1136/jme.29.3.165
pmid:12796437
pmcid:PMC1733720
fatcat:euf27l7k2jddzmh65qon4ozdqm
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
2016
Nature Neuroscience
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We did not find evidence of genetic overlap between schizophrenia risk and subcortical volume measures either at the level of common variant Franke et al. genetic architecture or for single genetic markers ...
The current study provides proof-of-concept (albeit based on a limited set of structural brain measures), and defines a roadmap for future studies investigating the genetic covariance between structural ...
The expected proportion under the null is 0.5. Nat Neurosci. Author manuscript; available in PMC 2016 August 01. ...
doi:10.1038/nn.4228
pmid:26854805
pmcid:PMC4852730
fatcat:d2celhhusravto6fr7g3fxvfqi
Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells
2013
Journal of Psychiatric Research
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controls from the Australian Schizophrenia Research Bank (ASRB). ...
Peripheral blood mononuclear cells (PBMCs) represent an accessible tissue source for gene expression profiling in schizophrenia that could provide insight into the molecular basis of the disorder. ...
using the Australian Schizophrenia Research Bank (ASRB). ...
doi:10.1016/j.jpsychires.2012.11.007
pmid:23218666
pmcid:PMC7094548
fatcat:pbxhgr5rivbyjgbnhy477x5a4i
Psychosis prevalence and physical, metabolic and cognitive co-morbidity: data from the second Australian national survey of psychosis
2013
Psychological Medicine
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., 44 The full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes ...
2014) 'Psychosis prevalence and physical, metabolic and cognitive co-morbidity : data from the second Australian national survey of psychosis. ...
Declaration of Interest D.C. has received grant monies for research from Eli Lilly, Janssen Cilag, Roche, Allergen, Bristol-Myers Squibb, Pfizer, Lundbeck, AstraZeneca and Hospira; travel support and honoraria ...
doi:10.1017/s0033291713002973
pmid:24365456
pmcid:PMC4045165
fatcat:yw5bauc7zbhfthyfnp7bprfwgi
Detecting motion signals of intent in schizophrenia
2014
Psychiatry Research
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Perceiving intent was generally intact in patients, despite the well-known difficulties with inferring intentional mental states in schizophrenia. ...
Compared to controls, patients had relatively higher hit rates for less direct compared to more direct chasing trials. ...
Recruitment was facilitated by the Australian Schizophrenia Research Bank (supported by the National Health and Medical Research Council of Australia), Pratt Foundation, Ramsay Health Care, Viertel Charitable ...
doi:10.1016/j.psychres.2014.06.012
pmid:25048755
fatcat:vios33qafvdftir6kkrzbpx77a
Genetic variants in Nogo receptor signaling pathways may be associated with early life adversity in schizophrenia susceptibility
2015
BBA Clinical
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Conclusions: Despite the lack of positive findings in our population after correction for multiple testing, previous gene expression and association studies in schizophrenia suggest the implication of ...
Nogo signaling is responsible for central nervous system myelin regulation and neurite outgrowth during neurodevelopment, and plasticity in the mature brain. ...
This study was supported by the Australian Schizophrenia Research Bank, which is supported by the National Health and Medical Research Council of Australia, the Pratt Foundation, Ramsay Health Care, the ...
doi:10.1016/j.bbacli.2014.11.008
pmid:26673096
pmcid:PMC4661513
fatcat:3oyoottxfzgfvkpqwv73laxbf4
An Australian Brain Bank: a critical investment with a high return!
2008
Cell and Tissue Banking
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Community support for this program is strong with over 2,000 people ...
The New South Wales Tissue Resource Centre (TRC) in the University of Sydney (Australia) is a human brain bank that can provide tissues to the neuroscience research community studying alcohol-related brain ...
The NSW TRC is supported by The University of Sydney, Schizophrenia Research Institute (SRI), National Institutes on Alcohol Abuse and Alcoholism (NIAAA-grant no: R01AAA01272508), Sydney South Western ...
doi:10.1007/s10561-008-9076-1
pmid:18543078
pmcid:PMC3391553
fatcat:t3gflhbhnfcifneymiru5bvzqm
The NSW brain tissue resource centre: Banking for alcohol and major neuropsychiatric disorders research
2016
Alcohol
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The New South Wales Brain Tissue Resource Centre (NSWBTRC) at the University of Sydney (Australia) is an established human brain bank providing tissue to the neuroscience research community for investigations ...
The NSWBTRC relies on wide community engagement to encourage those with and without neuropsychiatric illness to consent to donation through its allied research programs. ...
Acknowledgments The New South Wales Brain Tissue Resource Centre at the University of Sydney is supported by The University of Sydney and the Schizophrenia Research Institute. ...
doi:10.1016/j.alcohol.2016.02.005
pmid:27139235
pmcid:PMC4855871
fatcat:eat7nj6gtffyhmjisgndy6e2ci
BDNF SNPs Are Implicated in Comorbid Alcohol Dependence in Schizophrenia But Not in Alcohol-Dependent Patients Without Schizophrenia
2014
Alcohol and Alcoholism
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Comorbid alcohol dependence has a high prevalence in schizophrenia so we investigated the role of rs6265 in alcohol dependence in Australian populations of schizophrenia and alcohol-dependent patients. ...
When these SNPs were tested in the non-schizophrenia alcohol-dependent group we were unable to detect association. ...
Acknowledgements -This study was supported by the Australian Schizophrenia Research Bank (ASRB), which is supported by the National Health and Medical Research Council of Australia, the Pratt Foundation ...
doi:10.1093/alcalc/agu040
pmid:24993285
fatcat:t6zundggpvb3jb2cgyas6ueueq
White matter alterations between brain network hubs underlie processing speed impairment in patients with schizophrenia
2021
Schizophrenia Bulletin Open
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from the Australian Schizophrenia Research Bank. ...
Processing speed (PS) impairment is one of the most severe and common cognitive deficits in schizophrenia. ...
Acknowledgements We would like to acknowledge Jason Bridge for the management of data from the Australian Schizophrenia Research Bank. ...
doi:10.1093/schizbullopen/sgab033
pmid:34901867
pmcid:PMC8650074
fatcat:hcwrs3nczza4lc2vn4jkrpltoy
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