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Age-related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review

Benjamin Zimmerman, Bart Rypma, Gabriele Gratton, Monica Fabiani
2021 Psychophysiology  
This review aims at detailing how the physiology of the cerebral vascular system changes with age and how these changes lead to differential trajectories of cognitive maintenance or decline.  ...  Finally, we discuss the methodological implications of age-related changes in the cerebral vasculature for human cognitive neuroscience research and propose directions for future experiments aimed at investigating  ...  The mechanisms controlling the vasomotility at the core of the vascular response are complex and multi-faceted, and the role of changes in cerebrovascular reactivity in cognitive aging is a subject of  ... 
doi:10.1111/psyp.13796 pmid:33728712 pmcid:PMC8244108 fatcat:6eaxx226mrcnnjp3ascupmtz5q

End-tidal-to-arterial gas gradients during dynamic end-tidal forcing

Michael Martin Tymko
We sought to determine if the Pa-PETCO₂ affects the measurement of cerebrovascular reactivity (CVR) and the hypercapnic ventilatory response (HCVR), and whether it could be corrected for in subjects with  ...  (n=8) and without (n=7) a patent foramen ovale (PFO) during a CO₂ reactivity test.  ...  Specifically, Battisti-Charbonney and colleagues (15) advanced a non-linear approach to quantify CVR to CO2, whereby the cerebrovascular responses depart from linearity due to increases in arterial pressure  ... 
doi:10.14288/1.0166430 fatcat:alpsupcptzb45gwgzi6ghbl3eq