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Interactive specification of regions of interest on brain surfaces

Smadar Shiffman, Yi-Ren Ng, Thomas J Brosnan, Stephan Eliez, Jonathan M Links, Uma V Kelkar, Allan L Reiss
2003 NeuroImage  
We describe Surface Editor-a tool for interactive specification of regions of interest (ROIs) on brain surfaces.  ...  To validate Surface Editor we demonstrated that the program could be used to interactively delineate gyri on brain surfaces, and we showed that paths that the program generated were comparable to paths  ...  Acknowledgments We thank Ron Kimmel for the use of his geodesic-path software, and Nader Zaki, for his helpful comments on an earlier version of this manuscript.  ... 
doi:10.1016/j.neuroimage.2003.06.001 pmid:14642490 fatcat:djxz2unwvvfo3jvohqwo4wtqoi

Graphical neuroimaging informatics: Application to Alzheimer's disease

John Darrell Van Horn, Ian Bowman, Shantanu H. Joshi, Vaughan Greer
2013 Brain Imaging and Behavior  
Alzheimer's Disease is particularly interesting due to the wide-spread effects on cortical architecture and alterations of volume in specific brain areas associated with memory.  ...  Users can fluidly interact with an entire collection of cortical surfaces using only their mouse.  ...  Acknowledgments The authors wish to thank the faculty and staff of the Institute of Neuroimaging and Informatics of the University of Southern California and the Laboratory of Neuro Imaging (LONI) at the  ... 
doi:10.1007/s11682-013-9273-9 pmid:24203652 pmcid:PMC4012008 fatcat:ws5vsn5sizb53kkzdspyri3vru

Exploring Connectivity of the Brain's White Matter with Dynamic Queries

A. Sherbondy, D. Akers, R. Mackenzie, R. Dougherty, B. Wandell
2005 IEEE Transactions on Visualization and Computer Graphics  
Specifically, our application allows neuroscientists to place and interactively manipulate box-or ellipsoid-shaped regions to selectively display pathways that pass through specific anatomical areas.  ...  A representation of the cortical surface is provided for specifying queries of pathways that may be relevant to gray matter structures, and for displaying activation information obtained from functional  ...  ACKNOWLEDGMENTS We thank Roland Bammer and Michael Moseley of the Stanford University Lucas Center, for useful discussions and for developing the pulse sequences used to collect our data.  ... 
doi:10.1109/tvcg.2005.59 pmid:16138552 fatcat:wz4llh6jjna7dokqxy4kedroyq

Spatiotemporal imaging of brain activation using FreeSurfer

Thomas Witzel, Eric Halgren, Bruce R. Fischl, Arthur K. Liu, Seppo P. Ahlfors, Anders M. Dale
2001 NeuroImage  
The data were averaged over 8 subjects and the locations of the regions of interest are indicated on an inflated average surface of the left hemisphere.  ...  The results are presented in the form of movies of the changing spatial activation patterns, or by displaying the solution time courses for interactively selected regions of interest.  ... 
doi:10.1016/s1053-8119(01)91629-5 fatcat:mus45lcegzfg7hsbbuxgz6zl74

Visual Systems for Interactive Exploration and Mining of Large-Scale Neuroimaging Data Archives

Ian Bowman, Shantanu H. Joshi, John D. Van Horn
2012 Frontiers in Neuroinformatics  
Using a collection of cortical surface metrics and means for examining brain similarity, INVIZIAN graphically displays brain surfaces as points in a coordinate space and enables classification of clusters  ...  As an initial step toward addressing the need for such user-friendly tools, INVIZIAN provides a highly unique means to interact with large quantities of electronic brain imaging archives in ways suitable  ...  APPLICATION TO INDIVIDUAL BRAIN SUB-REGIONS When specifically investigating the AIBL and CNP study data, one might be primarily interested in identifying how hippocampal volume alone correlates with subject  ... 
doi:10.3389/fninf.2012.00011 pmid:22536181 pmcid:PMC3332235 fatcat:c3mgktgsj5hunlloxunizevqxm

Gender differences in cortical complexity

Eileen Luders, Katherine L Narr, Paul M Thompson, David E Rex, Lutz Jancke, Helmuth Steinmetz, Arthur W Toga
2004 Nature Neuroscience  
Cortical complexity, a measure that quantifies the spatial frequency of gyrification and fissuration of the brain surface, has not been thoroughly characterized with respect to gender differences in the  ...  Increased complexity implies more cortical surface area, which may offset gender differences in brain volume and account for behavioral gender differences.  ...  on brain expansion.  ... 
doi:10.1038/nn1277 pmid:15338563 fatcat:phegyx3f4zfghgk2wv72monory

Sex Differences in Medial Prefrontal and Parietal Cortex Structure in Children with Disruptive Behavior

Karim Ibrahim, Carla Kalvin, Fangyong Li, George He, Kevin A. Pelphrey, Gregory McCarthy, Denis G. Sukhodolsky
2020 Developmental Cognitive Neuroscience  
This study examined sex differences in gray matter volume in children with DBD in a priori regions-of-interest implicated in the pathophysiology of disruptive behavior.  ...  We then conducted a whole-brain analysis of cortical thickness to examine sex differences in regions not included in our hypothesis.  ...  Rebecca Jordan for their assistance with reviewing the final version of the manuscript, Dr. Megan Tudor for subject characterization assessments, and Ms. Emilie Bertschinger, Ms.  ... 
doi:10.1016/j.dcn.2020.100884 pmid:33254067 pmcid:PMC7704291 fatcat:zq7wp4th6ndafoiwgfxmhbaoge

Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism

Annelies van't Westeinde, Élodie Cauvet, Roberto Toro, Ralf Kuja-Halkola, Janina Neufeld, Katell Mevel, Sven Bölte
2019 Molecular Autism  
This difference might indicate sex-specific alterations of brain networks involved in autism symptom domains, especially within cortico-striatal and sensory integration networks.  ...  volume, surface area and thickness of neocortical, sub-cortical, and cerebellar networks.  ...  Competing interests  ... 
doi:10.1186/s13229-019-0309-x pmid:31893022 pmcid:PMC6937723 fatcat:upbmpagdmze47h5yphdqor2r7a

Regionally Specific Cortical Thinning and Gray Matter Abnormalities in the Healthy Relatives of Schizophrenia Patients

V. M. Goghari, K. Rehm, C. S. Carter, A. W. MacDonald
2006 Cerebral Cortex  
To investigate the nature of cortical abnormalities in the healthy relatives of patients, this study used magnetic resonance imaging to evaluate gray matter volume, surface area, and thickness of 13 regions  ...  Although findings are not entirely consistent, healthy relatives of schizophrenia patients also show abnormalities in cortical gray matter volume, suggesting that this may be one aspect of an unexpressed  ...  (C) Depicts the average brain (this brain is provided with FreeSurfer) to which each of individual brain was morphed and a selection of regions of interest labeled on this average brain (middle frontal  ... 
doi:10.1093/cercor/bhj158 pmid:16547347 fatcat:t24lwc34ujfopfsbm6ykno377e

Dorsal anterior cingulate cortex in typically developing children: Laterality analysis

Jue Wang, Ning Yang, Wei Liao, Han Zhang, Chao-Gan Yan, Yu-Feng Zang, Xi-Nian Zuo
2015 Developmental Cognitive Neuroscience  
Intrinsic connectivity analysis of these regions further revealed region-specific asymmetric connectivity profiles in dACC as well as their sex and age differences.  ...  We first replicated the previous finding observed in adults that gray matter density asymmetry in the dACC was region-specific: leftward (left > right) in its superior part, rightward (left < right) in  ...  Richard Betzel from University of Pennsylvania for help with language editing and proof reading of the manuscript.  ... 
doi:10.1016/j.dcn.2015.10.002 pmid:26602957 pmcid:PMC6989820 fatcat:iu7sfxmvfvew5p3nkvbkmybxce

Gyrification changes are related to cognitive strengths in autism

P. Duret, F. Samson, B. Pinsard, E.B. Barbeau, A. Boré, I. Soulières, L. Mottron
2018 NeuroImage: Clinical  
We calculated the local Gyrification Index (lGI) throughout an occipito-temporal region of interest and independently modeled age and peak of ability effects for each group.  ...  Unique regional maturation trajectories in the autistic brain may underline specific cognitive strengths, which are key variables for understanding heterogeneity in autism.  ...  Financial disclosure All the authors of this paper declare no financial interest or potential conflict of interest.  ... 
doi:10.1016/j.nicl.2018.04.036 pmid:30128280 pmcid:PMC6095946 fatcat:ry43oxlj7fbbjnerqxraj2ziw4

The Relationship between Brain Structure and Proficiency in Reading and Mathematics in Children, Adolescents, and Emerging Adults

G.A. Torre, A.A. Matejko, G.F Eden
2020 Developmental Cognitive Neuroscience  
When dividing the dataset into three age-specific subgroups, cortical thickness of the left supramarginal gyrus (SMG) and fusiform gyrus (FG) correlated with reading ability in the oldest subgroup (15-  ...  Here, we investigated relationships between individual differences in reading and math ability (single word reading and calculation) with brain anatomy (cortical thickness and surface area) in 342 participants  ...  Regions of interest (ROIs) We focused our analyses on brain regions shown in the published literature to be engaged in reading, math, or both, in children and adults.  ... 
doi:10.1016/j.dcn.2020.100856 pmid:32949854 pmcid:PMC7502824 fatcat:eknky3ks2rgzdbowuijcaqzcmm

Double dissociation in the anatomy of socioemotional disinhibition and executive functioning in dementia

Casey E. Krueger, Victor Laluz, Howard J. Rosen, John M. Neuhaus, Bruce L. Miller, Joel H. Kramer
2011 Neuropsychology  
Regions of interest (ROIs) included anterior cingulate cortex (ACC), orbitofrontal cortex (OFC), middle frontal gyrus (MFG) and inferior frontal gyrus (IFG).  ...  Brain regions significantly correlated with disinhibition (ACC, OFC, IFG, and temporal lobes) and EF (MFG) were entered into separate hierarchical regressions to determine which brain regions predicted  ...  Our approach, which was designed to test whether our regions of interest accounted for specific behaviors independent of other relevant brain regions in the frontal lobes, constitutes a relative strength  ... 
doi:10.1037/a0021681 pmid:21381829 pmcid:PMC3075812 fatcat:qxrbvyfyh5fsja3ns42mll5vha

Frontal and temporal contributions to understanding the iconic co-speech gestures that accompany speech

Anthony Steven Dick, Eva H. Mok, Anjali Raja Beharelle, Susan Goldin-Meadow, Steven L. Small
2012 Human Brain Mapping  
Using fMRI during naturalistic story comprehension, we examined which brain regions in the listener are sensitive to speakers' iconic gestures.  ...  Hum Brain Mapp 35:900-917, in Wiley Online Library (  ...  We related the participants' processing of the narratives (based on a post-scan recognition test) to the brain response in our defined regions of interest.  ... 
doi:10.1002/hbm.22222 pmid:23238964 pmcid:PMC3797208 fatcat:2qtbslrmuzenplr5tajup6ndey

Language Differences in the Brain Network for Reading in Naturalistic Story Reading and Lexical Decision

Xiaojuan Wang, Jianfeng Yang, Jie Yang, W. Einar Mencl, Hua Shu, Jason David Zevin, Wang Zhan
2015 PLoS ONE  
We found a very different pattern of language effects in a naturalistic reading paradigm, during which significant differences were only observed in visual regions not typically considered specific to  ...  Specifically, language differences were most pronounced in MFG and rFFG during the lexical decision task, whereas no language differences were observed in these areas during silent reading of text for  ...  Acknowledgments The authors thank Zhichao Xia for his work on data collection, and Ken Pugh and Mark Seidenberg for comments on an earlier draft. Author Contributions  ... 
doi:10.1371/journal.pone.0124388 pmid:26017384 pmcid:PMC4446262 fatcat:lco5gk7tmzgnjnrvr6uwmlnncm
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