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Big data and extreme-scale computing

M Asch, T Moore, R Badia, M Beck, P Beckman, T Bidot, F Bodin, F Cappello, A Choudhary, B de Supinski, E Deelman, J Dongarra (+27 others)
2018 The international journal of high performance computing applications  
Third, we focus on some opportunities for software ecosystem convergence in big, logically centralized facilities that execute large-scale simulations and models and/or perform large-scale data analytics  ...  simulations and models or that perform large-scale data analytics.  ...  Many scientific applications at extreme scale already need aggressive data reduction.  ... 
doi:10.1177/1094342018778123 fatcat:vwrrxmad4rhtppq6ioaz4h5q7a

A systematic analysis of protein interaction networks leading to the drug discovery

Shun-ichiro IEMURA, Tohru NATSUME
2008 Synthesiology English edition  
We were able to achieve large-scale protein network analysis with high sensitivity, high reproducibility, and high efficiency, by newly developing liquid chromatography system with extremely low flow rate  ...  Our research developed into Full Research that led to the development of new diagnostic and treatment methods as well as new drug discovery targets. on large-scale analysis of protein interaction using  ...  environment, 3) adjustment of analytical f low passage with minimum dead volume, and 4) optimization of sample preparation, toward the objective "to construct ultra high-sensitivity mass spectrometry  ... 
doi:10.5571/syntheng.1.114 fatcat:wlpkmm4ozjhshgsya25b4rw4h4

B. Interactive poster presentations

2011 Psychology and Health  
cancer and its treatment, social support, attitudes towards cancer treatment, social norms and Self efficacy for behaviours related to coping with cancer.  ...  Methods: A quantitative, analytic-correlational study with a sample of 105 nurses.  ... 
doi:10.1080/08870446.2011.617185 fatcat:pdmyqchhezgxlf6vqhn6uxhuei

Proteomics and Host–Pathogen Interactions [chapter]

D.G. Biron, D. Nedelkov, D. Missé, P. Holzmuller
2017 Genetics and Evolution of Infectious Diseases  
Figure 11 . 2 112 Pathogeno-proteomics: integrating analytical levels in hostevectorepathogen interactions.  ...  What are the hostepathogen cross talks at individual and population scales in a habitat?  ... 
doi:10.1016/b978-0-12-799942-5.00011-1 fatcat:ovzyxvgsebcefhbyaa5uyqs3wy

Proteomics and Host—Pathogen Interactions [chapter]

David G. Biron, Dobrin Nedelkov, Dorothée Missé, Philippe Holzmuller
2011 Genetics and Evolution of Infectious Disease  
toward high resistance.  ...  Figure 11 . 1 111 Pathogeno-proteomics: integrating analytical levels in hostÀvectorÀpathogen interactions.  ... 
doi:10.1016/b978-0-12-384890-1.00011-x fatcat:zy7ey4paancnjcg774hjnuufdi

Social extremity, communities of fate, and the sociology of SARS

Peter Baehr
2006 European Journal of Sociology  
These are intriguing possibilities that only research, and greater analytical precision, could substantiate.  ...  In the following discussion, community of fate is a term that depicts a process of group formation under extreme duress.  ... 
doi:10.1017/s000397560500007x fatcat:jxqurnmbajdpjbjx42o3raasgm

Nurturing breakthroughs: lessons from complexity theory

D. Sornette
2008 Journal of Economic Interaction and Coordination  
In other words, bubbles, which are characteristic definitions of human activity, allow huge risks to get huge returns over large scales.  ...  Let us unleash the battle of giants between extraordinary discoveries and extreme catastrophes.  ...  In a word, bubbles (collective over-enthusiasm) seem a necessary evil to foster our collective attitude towards risk taking and break the stalemate of society resulting from its tendency towards risk avoidance  ... 
doi:10.1007/s11403-008-0040-8 fatcat:znthv6b3mjcpdkfp5uuz5tha3a

Systems Biology Approaches Towards Immunity against Plasmodium [chapter]

Himangshu Patgiri, Ankita Khataniar, Pitimoni Boro, Sushmita Baishnab, Sanchaita Rajkhowa
2022 Mosquito Research - Recent Advances in Pathogen Interactions, Immunity, and Vector Control Strategies [Working Title]  
Here, the numerous experimental and computational works with the ongoing methodologies using Systems Biology approaches along with the interactions of host and pathogen will be discussed.  ...  of the body have been recently studied in malaria host-pathogen interactions effectively and also in other diseases, such as cancer.  ...  and vaccines in the battle against malaria.  ... 
doi:10.5772/intechopen.104614 fatcat:6v6ft2jsuvetjmi5newyfsm2l4

Interactions between Medicine and the Arts

Wolfgang Schütz
2020 Wiener Klinische Wochenschrift  
This orientation towards cell-to-cell interactions and, subsequently, towards molecular structures strengthened the focus on biological mechanisms but entailed little or no emphasis on the social dimensions  ...  As book artist/cancer patient Martha Hall has written, "people may not want to touch the topics I explore in my books. Yet the books invite handling, touching, interaction" [63] .  ... 
doi:10.1007/s00508-020-01706-w pmid:32885285 fatcat:j67dk5juxfcnlo2uldlmxvwnhi

The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction

Nazanin Hoshyar, Samantha Gray, Hongbin Han, Gang Bao
2016 Nanomedicine  
Here we review the effects of nanoparticle size on cellular interaction and in vivo pharmacokinetics, including cellular uptake, biodistribution and circulation half-life of nanoparticles.  ...  With advances in understanding the effect of nanoparticle size on interactions with the human body, both through models and experimentation, researchers are moving towards implementing nanoparticles as  ...  Particles on the micrometer scale remain in the body much longer than particles on the nanometer scale [51] .  ... 
doi:10.2217/nnm.16.5 pmid:27003448 pmcid:PMC5561790 fatcat:xdbo5nqelve67gdklmpsoeskze

Understanding the humanistic interaction with medical imaging technology

F. Murphy
2001 Radiography  
In conclusion, the model is considered to be a valid conceptual representation of the interactions within the context of the naturalistic setting.  ...  Word Count : 99,542 Summary This study set out to discover the nature of the interactions that occur between the radiographer, patient and high technology imaging equipment.  ...  The examination of `self requires analytical perspectives for understanding reality and it was at this point that symbolic interaction was introduced.  ... 
doi:10.1053/radi.2001.0328 fatcat:3dsbfzfmbrcphb3qsw2xfixuve

Interactions between persons—Knowledge, decision making, and the co‐production of practice

Michael Loughlin, Stephen Buetow, Michael Cournoyea, Samantha Marie Copeland, Benjamin Chin‐Yee, K.W.M. Fulford
2019 Journal of Evaluation In Clinical Practice  
scientific knowledge and the significance of viewing clinical knowledge not as something that "sits within the minds" of researchers and practitioners, but as a relational concept, the product of social interactions  ...  towards women's knowledge and how important SDM was to practitioners.  ...  surgery, and especially in diagnostic work-up because of a small suspicion of lung cancer.  ... 
doi:10.1111/jep.13297 pmid:31733025 fatcat:fmf4xlndqfhr3bgzzhwrz7wbfy

Mixed strategy game models for generating baseline data on the water–air interactions [chapter]

Sunday A. Reju, Namibia University of Science and Technology, Gabriel S. Mbokoma, Nnenesi A. Kgabi, Namibia University of Science and Technology, North-West University
2021 Water Security and Climate Adaptation in Southern Africa  
SPI scale SPI values Drought scale ≤-2.0 Extremely dry (-1.99) to (-1.5) Severely dry (-1.49) to (-1.0) Moderately dry (-0.99) to (+0.99) Normal (+1.0) to (+1.49) Moderately wet (+1.5  ...  Katima Mulilo location Index Drought scale Extreme- ly dry Severely dry Normal Normal Normal Very wet Extreme- ly wet Katima Mulilo SPI 1 ≤-2 -1.5 -0.5 0 0.5 1.5 ≥2 Frequency  ...  Water security and extreme precipitation indices of selected towns in Namibia Mixed strategy game models for generating baseline data Windhoek, Namibia Chapter 6 Chapter 5 Chapter 8 Chapter 9 Postscript  ... 
doi:10.4102/aosis.2020.bk205.05 fatcat:2yf4a6impnbtbirce6tz4ht37q

Interaction modulation through arrays of clustered methyl-arginine protein modifications

Jonathan Woodsmith, Victoria Casado-Medrano, Nouhad Benlasfer, Rebecca L Eccles, Saskia Hutten, Christian L Heine, Verena Thormann, Claudia Abou-Ajram, Oliver Rocks, Dorothee Dormann, Ulrich Stelzl
2018 Life Science Alliance  
tunable protein interaction interface.  ...  leverages these disordered sequences to mediate cellular interactions.  ...  We first established an analytical framework to control for overall expression patterns of targeted proteins (see the Materials and Methods section).  ... 
doi:10.26508/lsa.201800178 pmid:30456387 pmcid:PMC6238616 fatcat:ugof4bo5fje33okpfz4xbjzvkq

Interactive Tools for Reproducible Science – Understanding, Supporting, and Motivating Reproducible Science Practices [article]

Sebastian Stefan Feger
2020 arXiv   pre-print
On the one hand, this transition towards computational and data-intensive science poses new challenges for research reproducibility and reuse.  ...  This thesis paves new ways for interaction with RDM tools that support and motivate reproducible science.  ...  Technology supporting user-initiated/unaware interactions might make an important contribution towards acceptance.  ... 
arXiv:2012.02570v1 fatcat:ejqwev3kybajtnwozt6zfewway
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