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Integrated Cantilever-Based Flow Sensors with Tunable Sensitivity for In-Line Monitoring of Flow Fluctuations in Microfluidic Systems
2013
Sensors
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Finally, we demonstrate the ability to perform in-line monitoring of flow fluctuations in a microfluidic system using the integrated cantilever-like sensor. ...
In-line measurement of flow fluctuations in the microfluidic system with an integrated flow sensor allows the characterization of the fluidic noise. ...
Conflicts of Interest The authors declare no conflict of interest. ...
doi:10.3390/s140100229
pmid:24366179
pmcid:PMC3926555
fatcat:qodwnjuepbagpdodtnhypdeny4
Microfluidic and Micromachined/MEMS Devices for Separation, Discrimination and Detection of Airborne Particles for Pollution Monitoring
2019
Micromachines
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Most of the microfluidics-related literature describes devices handling liquids, with only a small part dealing with gas-based applications, and a much smaller number of papers are devoted to the separation ...
due to their inherent capability of being integrated in lab-on-chip (LOC) type of smart microsystems with increased functionalities that can be portable and are easy to use. ...
Capacitive sensors have the advantage that they can be easily integrated with circuits in CMOS ICs to provide a much more performant system in terms of sensitivity. ...
doi:10.3390/mi10070483
pmid:31323826
pmcid:PMC6681025
fatcat:oypxrhks6rdenho3c5sukm4o4u
Suspended microchannel resonators for biomolecular detection
2003
Applied Physics Letters
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Microfabricated resonant mass sensors are among the most sensitive devices for chemical detection, but degradation of the sensitivity in liquid has so far hindered their successful application in biology ...
Integrating microfluidic detect ion and sample-preparat ion can greatly leverage experimental efforts in systems biology and pharmaceutical research by increasing analysis throughput while dramatically ...
The influence of flow rate, diffusivity, and sensor geometry on kinetic measurements has been studied extensively for commercial surface plasmon resonance based instruments whose flow chamber is a microfluidic ...
doi:10.1063/1.1611625
fatcat:t5tabhmd35fcdnsffvrb3rfwxu
Label-free biological and chemical sensors
2010
Nanoscale
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Highly sensitive, label-free biodetection methods have applications in both the fundamental research and healthcare diagnostics arenas. ...
Additionally, a more in-depth discussion of optical devices, surface functionalization methods to increase device specificity, and fluidic techniques to improve sample delivery will be reviewed. ...
sensors with parylene microfluidics. 169 Using this type of integrated device, changes in cellular behavior in response to fluid shear stress were detected by monitoring the change in the mechanical ...
doi:10.1039/c0nr00201a
pmid:20820687
fatcat:5fi4xzbwgzgdlpochxb2ir6wdi
Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions
2017
Biosensors & bioelectronics
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This review will also highlight the integrated on-chip systems for isolation and characterization of EVs. ...
Advances in microfluidics allow for chemical sampling with increasingly high spatial resolution and under precise manipulation down to single molecule level. ...
Mohsen Akbari acknowledges Natural Sciences and Engineering Research Council of Canada (NSERC) for funding. ...
doi:10.1016/j.bios.2016.12.062
pmid:28088752
pmcid:PMC5323331
fatcat:edr5hed6dvaijapwffq5rkudva
Integrating Biosensors in Organs-on-Chip Devices: A Perspective on Current Strategies to Monitor Microphysiological Systems
2020
Biosensors
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However, the urgent demand for continuous, noninvasive, and real-time monitoring of tissue constructs requires the direct integration of biosensors. ...
Biosensors for monitoring biological models with metabolic activities, models with tissue barrier functions, as well as models with electromechanical properties will be described and critically evaluated ...
[92] developed a microfluidic device integrated with aptamer-based sensors for continuous monitoring of transforming growth factor-beta (TGF-β) signaling in hepatocytes and stellate cells coculture ...
doi:10.3390/bios10090110
pmid:32872228
fatcat:vrbvsqzxrzf4xizsvav7hx6ihy
Table of Contents
2019
Journal of Physics, Conference Series
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This work is being conducted in the NSF funded ERC Center on Advanced Self-Powered Systems of Integrated Sensors and Technologies (ASSIST). ...
Active AFC-MEAs were combined by integrating OH--permeable electrolyte into micro-channels of MEMS-based membranes. ...
The device consists of two cantilever-type sensors for the forces monitoring. ...
doi:10.1088/1742-6596/1407/1/011002
fatcat:5ttgm2jqtfgr3jf55i22inzuq4
Microelectromechanical Systems and Nephrology: The Next Frontier in Renal Replacement Technology
2013
Advances in Chronic Kidney Disease
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Next, a survey of MEMS devices being developed for various biomedical applications will be illustrated with current examples. ...
The future landscape of clinical medicine and research will only see further expansion of MEMS based technologies in device designs and applications. ...
Cheong et al. have designed a MEMS based pressure sensor for monitoring blood flow in prosthetic vascular grafts. 104 The implantable device uses a silicon nanowire sensor with tunable piezoresistivity ...
doi:10.1053/j.ackd.2013.08.006
pmid:24206604
pmcid:PMC3866020
fatcat:5hqtwigv6bbl5e5wr7to6pe2ei
Micro Total Analysis Systems: Fundamental Advances and Applications in the Laboratory, Clinic, and Field
2012
Analytical Chemistry
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or in environmental monitoring. ...
Another strength of μTAS lies in the creation of multicellular communities, for example, the combination of many cell types into an interacting system to explore intercellular communication. ...
Acknowledgments The authors thank Jessica Park Lindsey for preparing the table of contents graphic. ...
doi:10.1021/ac3031543
pmid:23140554
pmcid:PMC3546124
fatcat:6zpniz3pkbasveawfmooodsvk4
MEMS Resonant Mass Sensor With Integrated Optical Manipulation
2018
IEEE transactions on nanotechnology
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We investigate optical manipulation of particles in fluid as a viable method to achieve better experimental fidelity and extend the application of integrated-fluidic resonant-mass sensing. ...
Fluctuations in sample position or trajectory can lead to measurement error, thereby degrading the resolution with which these devices can accurately characterize mass. ...
CONCLUSION The sensor described in this letter unites the techniques of optical trapping and MEMS resonant mass sensing in a microfluidic-enabled device. ...
doi:10.1109/tnano.2018.2819939
fatcat:4hm47geknzaita4yptmvjls3fi
Opto-Mechanical Photonic Crystal Cavities for Sensing Application
2020
Applied Sciences
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In this review, we introduce basic physical concepts of opto-mechanical PhC system and describe typical experimental systems for sensing applications. ...
On account of their high-quality factors and small mode volumes as well as good on-chip integrability with waveguides/circuits, photonic crystal (PhC) cavities have attracted great attention in sensing ...
Conflicts of Interest: The authors declare no conflict of interest. ...
doi:10.3390/app10207080
fatcat:52kvkq3kfvfy7i5j5a4h5ohghm
Ultrafine Aerosol Particle Sizer Based on Piezoresistive Microcantilever Resonators with Integrated Air-Flow Channel
2021
Sensors
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To monitor airborne nano-sized particles (NPs), a single-chip differential mobility particle sizer (DMPS) based on resonant micro cantilevers in defined micro-fluidic channels (µFCs) is introduced. ...
Mobility sizing in 4 bins of a nebulized carbon aerosol NPs is demonstrated based on finite element modelling (FEM) combined with a-priori knowledge of particle charge state. ...
Conflicts of Interest: The authors declare no conflict of interest. ...
doi:10.3390/s21113731
pmid:34072041
fatcat:hmxnavg5tbdy5dgxahykrtzjdu
Recent Advances in Application of Biosensors in Tissue Engineering
2014
BioMed Research International
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In this review, we provide an overview of the recent advancements in biosensors for tissue engineering applications. ...
In recent years, there has been a growing interest in application of novel biosensors in cell culture and tissue engineering, for example, real-time detection of small molecules such as glucose, lactose ...
Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper. ...
doi:10.1155/2014/307519
pmid:25165697
pmcid:PMC4140114
fatcat:e4ipgwnyvja4holnq75zefvpdm
Progress of infrared guided-wave nanophotonic sensors and devices
2020
Nano Convergence
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Guided-wave nanophotonics paves the way to miniaturize the sensors and realize on-chip integration of various photonic components, so as to realize chip-scale sensing systems for the future realization ...
Starting from the popular CMOS-compatible silicon nanophotonics in the infrared, many infrared guided-wave nanophotonic sensors have been developed, showing the advantages of high sensitivity, low limit ...
Authors' contributions YM, BD, and CL contributed to the preparation of the manuscript. YM and BD contributed equally to this work. CL supervised the overall conception. ...
doi:10.1186/s40580-020-00222-x
pmid:32239361
fatcat:zxljikq4afa7ravknpul42hp5a
Single nanoparticle detectors for biological applications
2012
Nanoscale
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In this article, we discuss the recent progress and future directions in the area of single nanoparticle detectors with an emphasis on their biological applications. ...
Development of novel detection and characterization tools for nanoparticles will impact a broad range of disciplines in biological research from nanomedicine to nanotoxicology. ...
Acknowledgements This work was supported in part by US Army Research Laboratories (ARL) grant W911NF-06-2-0040. ...
doi:10.1039/c2nr11562j
pmid:22214976
pmcid:PMC3759154
fatcat:sflcjeljsje4vj5w64cmiac45a
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