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The annotation of surface exposed bacterial membrane proteins is an important step in interpretation and validation of proteomic experiments. ... Conclusions: Inmembrane easily integrates predictions from both local binaries and web-based queries to help gain an overview of likely surface exposed protein in a bacterial proteome. ... One existing workflow for annotation of PSE proteins is the program SurfG+  , which focuses on Gram-positive bacterial proteomes. ...doi:10.1186/1751-0473-8-9 pmid:23506117 pmcid:PMC3668253 fatcat:5irveoi6v5dnbc4lcvkqjpy6va