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Designing Future Warehouse-Scale Computers for Sirius, an End-to-End Voice and Vision Personal Assistant

Johann Hauswald, Trevor Mudge, Vinicius Petrucci, Lingjia Tang, Jason Mars, Michael A. Laurenzano, Yunqi Zhang, Hailong Yang, Yiping Kang, Cheng Li, Austin Rovinski, Arjun Khurana (+1 others)
2016 ACM Transactions on Computer Systems  
As user demand scales for intelligent personal assistants (IPAs) such as Apple's Siri, Google's Google Now, and Microsoft's Cortana, we are approaching the computational limits of current datacenter (DC  ...  In this article, we present the design of Sirius, an open end-to-end IPA Web-service application that accepts queries in the form of voice and images, and responds with natural language.  ...  VIII Homogeneous DC Hmg. Table IX . IX Heterogeneous DC Hetero. Latency Hetero. TCO (with L constraint) Hetero. Power Eff.  ... 
doi:10.1145/2870631 fatcat:aakausm5lfbfbkhr2oycpe5ufa

Operating system support for overlapping-ISA heterogeneous multi-core architectures

Tong Li, Paul Brett, Rob Knauerhase, David Koufaty, Dheeraj Reddy, Scott Hahn
2010 HPCA - 16 2010 The Sixteenth International Symposium on High-Performance Computer Architecture  
This design, however, faces significant challenges in the operating system, which traditionally assumes only homogeneous hardware.  ...  We have implemented these algorithms in the Linux 2.6.24 kernel and evaluated them on an actual heterogeneous platform.  ...  Acknowledgments We are grateful to Sean McElderry for the BIOS modifications, Srinivas Chennupaty and Avinash Sodani for valuable comments and suggestions, and discussions with Ajay Bhatt, Dan Baumberger  ... 
doi:10.1109/hpca.2010.5416660 dblp:conf/hpca/LiBKKRH10 fatcat:grpvb2k2rzesbiuuvkew4i54a4

Integrated value chains and their implications from a business and technology standpoint

Michael P Papazoglou, Piet Ribbers, Aphrodite Tsalgatidou
2000 Decision Support Systems  
to the challenge of integrated value chains. q  ...  In this paper, we review the business and technological requirements of modern extended organizations and explain how adaptive business objects and controlled interoperability are the key enabling technologies  ...  These requirements are handled by the homogeneous process model approach and the heterogeneous process approaches that support integration of multiple Ž process models either homogeneous homogeneous .  ... 
doi:10.1016/s0167-9236(00)00081-6 fatcat:fow4fyy4yvgfzpsoq2idy7lu4i

Multiple Mobile Robot Systems [chapter]

Lynne E. Parker
2008 Springer Handbook of Robotics  
Key open research questions remain in the broad areas of system integration, robustness, learning, scalability, generalization, and dealing with hetero-geneity.  ...  The first, the Nerd Herd, is representative of a pure swarm robotics approach using large numbers of homogeneous robots.  ... 
doi:10.1007/978-3-540-30301-5_41 fatcat:v3yo5joepja2lketepmahupkfm

Modeling and Simulation of Systems of Systems – a Survey

Anjel Tzanev
2013 Cybernetics and Information Technologies  
The conceptions about SoS simulation modeling, subsystem integration and practical implementation issues in the face of main three tendencies for development (academic, military and industrial) are considered  ...  The paper surveys the current state of the art and perspectives in the theoretical and practical achievements at the area of Systems of Systems (SoS) and SoS Engineering (SoSE).  ...  The EF approach enables simulated and real-time data in the system information exchange and processing.  ... 
doi:10.2478/cait-2013-0011 fatcat:2b4r3xbuovfnhjt3ci676p4yxu

Enterprise application integration

2001 Work Study  
Acknowledgement The author would like to thank Michael Haeberlen, Andrew James, and Sven Stueven for their contributions to bring the system described in the article to life.  ...  However, incremental development has to follow an overall plan as well, triggered by the "milestones" of released increments.  ...  More appropriate seems an incremental approach: starting with a kernel ontology, which is stepwise extended by "ontology increments" i.e. partial formalisations of particular subdomains.  ... 
doi:10.1108/ws.2001.07950eaf.003 fatcat:24cylq44pjejjkzdtf2uib6nyq

QT Assessment in Early Drug Development: The Long and the Short of It

Robert M. Lester, Sabina Paglialunga, Ian A. Johnson
2019 International Journal of Molecular Sciences  
Consequently, there has been a paradigm shift to assess a compound's cardiac risk of arrhythmias centered on a mechanistic approach to arrhythmogenesis rather than focusing solely on the QT interval.  ...  While prolongation or shortening of the QT interval may herald the appearance of serious cardiac arrhythmias, the positive predictive value of an abnormal QT measurement for these arrhythmias is modest  ...  In these cases, data from the SAD investigation may be combined with pharmacokinetic (PK) and pharmacodynamic data from a complementary MAD study assuming that clinical conduct of both trials is homogeneous  ... 
doi:10.3390/ijms20061324 fatcat:252k22yvsrbajahkws7yzxguh4

Ethylene oxide: an assessment of the epidemiological evidence on carcinogenicity

R E Shore, M J Gardner, B Pannett
1993 Occupational and Environmental Medicine  
The magnitude and consistency of the standardised mortality ratios (SMRs) were evaluated for the individual and combined studies, as well as trends by intensity or frequency of exposure, by duration of  ...  This paper presents a review and meta-analysis of these studies, primarily for leukaemia, non-Hodgkin's lymphoma, stomach cancer, pancreatic cancer, and cancer of the brain and nervous system.  ...  The approach of ignoring the heterogeneity and calculating the overall SMR and its confidence interval in the same way as when the data are homogeneous has commonly been used, but its inadequacy has increasingly  ... 
doi:10.1136/oem.50.11.971 fatcat:f5mgwibwajamdl3fin2erp5hfa

Ethylene oxide: an assessment of the epidemiological evidence on carcinogenicity

R E Shore, M J Gardner, B Pannett
1993 British Journal of Industrial Medicine  
Although the current data do not provide consistent and convincing evidence that EtO causes leukaemia or non-Hodgkin's lymphoma, the issues are not resolved and await further studies of exposed populations  ...  The magnitude and consistency of the standardised mortality ratios (SMRs) were evaluated for the individual and combined studies, as well as trends by intensity or frequency of exposure, by duration of  ...  The approach of ignoring the heterogeneity and calculating the overall SMR and its confidence interval in the same way as when the data are homogeneous has commonly been used, but its inadequacy has increasingly  ... 
pmid:8280635 pmcid:PMC1035533 fatcat:m76snhyreraklo6t5uv4wxva2m

Data cube and cloud resources as platform for seamless geospatial computation

Giuliano Andrea Pagani, Luca Trani
2018 Proceedings of the 15th ACM International Conference on Computing Frontiers - CF '18  
Those will be natural extensions that, thanks to the flexibility and modularity of our approach, could be integrated incrementally without disrupting the methodology's philosophy and conceptual backbone  ...  The data cube is a powerful abstraction that offers an approach to organise information in a common structure along homogeneous dimensions.  ... 
doi:10.1145/3203217.3205861 dblp:conf/cf/PaganiT18 fatcat:6dtd24cgibfx5ob3qkykfgbjvq

Defense Advanced Research Projects Agency (Darpa) Fiscal Year 2016 Budget Estimates

Department Of Defense Comptroller's Office
2015 Zenodo  
The Defense Advanced Research Projects Agency (DARPA) FY2016 amounted to $2.868 billion in the President's request to support high-risk, high-reward research.  ...  -Generate design intent and the initial materials solution for a baseline hypersonic flight trajectory. -Establish and populate the data warehouse for initial boost-glide aeroshell data.  ...  The Basic Research part of this program focused on the development of new hetero-integration processes and capabilities that were demonstrated in application-specific circuits and transferred into the  ... 
doi:10.5281/zenodo.1215366 fatcat:cqn5tyfixjanzp5x3tgfkpedri

International Journal of Business and Management, Vol. 3, No. 2, February 2008

Editior IJBM
2009 International Journal of Business and Management  
The five forces are the threat of new entrants, the bargaining power of buyers, the bargaining power of suppliers, the threat of substitutes and the intensity of the rivalry of industry competitors.  ...  An internal analysis serves to locate the strengths and weaknesses of the firm. The authors of all three textbooks mentioned above allude to Porter's Five Force Model of industry competition.  ...  However a key example of on-site assembly has been outlined by Collins et al (1997) who described two versions of the on-site approach; integrated, categorised by integrated on-site 'hole in the wall'  ... 
doi:10.5539/ijbm.v3n2p0 fatcat:qlv7lmsmxjgghl7oobodmqb6na