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In Vivo Evaluation of Large-Scale IR-Based Traceability Recovery

Markus Borg
2011 2011 15th European Conference on Software Maintenance and Reengineering  
Case studies have showed promising results, but no large-scale in vivo evaluations have been made.  ...  Their aim is to collect different pieces of information in one system. Our ambition is to develop an IR-based traceability recovery plug-in to this tool.  ...  Evaluate approach in an in vivo industrial environment The aim of this study will be to evaluate how well the IR-based approach to traceability recovery works in a real industrial setting.  ... 
doi:10.1109/csmr.2011.54 dblp:conf/csmr/Borg11 fatcat:ojq2dtbptbalzcxoxj6ofbokla

Evaluation of traceability recovery in context: a taxonomy for information retrieval tools

M. Borg, P. Runeson, L. Broden
2012 16th International Conference on Evaluation & Assessment in Software Engineering (EASE 2012)  
Finally, we discuss how empirical evidence of the feasibility of IR-based traceability recovery can be strengthened in future research.  ...  Method: To illustrate this issue, we have adapted a framework of general IR evaluations to a context taxonomy specifically for IR-based traceability recovery.  ...  of IR-based traceability recovery evaluations.  ... 
doi:10.1049/ic.2012.0014 dblp:conf/ease/BorgRB12 fatcat:lfugdlj3h5g5tnstmwc4k6isxq

Advancing Trace Recovery Evaluation - Applied Information Retrieval in a Software Engineering Context [article]

Markus Borg
2016 arXiv   pre-print
Finally, we present how tools and methods are evaluated in the general field of IR research, and propose a taxonomy of evaluation contexts tailored for IR-based trace recovery.  ...  The work contains a Systematic Literature Review (SLR) of previous evaluations of IR-based trace recovery.  ...  Consequently, the case appears to be suitable for evaluating IR-based trace recovery in an in-vivo setting.  ... 
arXiv:1602.07633v1 fatcat:a5df75muvzhkfjjwrllptusc4i

Recovering from a decade: a systematic mapping of information retrieval approaches to software traceability

Markus Borg, Per Runeson, Anders Ardö
2013 Empirical Software Engineering  
Engineers in large-scale software development have to manage large amounts of information, spread across many artifacts.  ...  The objective of this study is to produce a map of work on IR-based trace recovery, with a particular focus on previous evaluations and strength of evidence.  ...  Appendix: Classification of Primary Publications  ... 
doi:10.1007/s10664-013-9255-y fatcat:s7oz6jzovze3tbhswlpnp235ty

Self-indicating, fully active pharmaceutical ingredients nanoparticles (FAPIN) for multimodal imaging guided trimodality cancer therapy

Xiangdong Xue, Yee Huang, Xinshuai Wang, Zhongling Wang, Randy P. Carney, Xiaocen Li, Ye Yuan, Yixuan He, Tzu-yin Lin, Yuanpei Li
2018 Biomaterials  
The relative fluorescence quantum yields of Pa and Ir in PaIr NPs The relative fluorescence quantum yields were calculated as previously described [28] , following the equation: Xue et al.  ...  Conventional drug delivery systems contain substantial amounts of excipients such as polymers and lipids, typically with low drug loading capacity and lack of intrinsic traceability and multifunctionality  ...  In vivo evaluations of therapeutic efficacy PDX GBM-bearing mice were employed for in vivo therapeutic efficacy evaluation.  ... 
doi:10.1016/j.biomaterials.2018.01.044 pmid:29421556 pmcid:PMC5846343 fatcat:nkbapdex4nfbxga3zhv6mt7wey

Metrology and nano-mechanical tests for nano-manufacturing and nano-bio interface: Challenges & future perspectives

E.P. Koumoulos, S.A.M. Tofail, C. Silien, D. De Felicis, R. Moscatelli, D.A. Dragatogiannis, E. Bemporad, M. Sebastiani, C.A. Charitidis
2018 Materials & design  
Laboratory-based characterization of nanomaterials has been the key enabler in the growth of nanotechnology and nano-enabled products.  ...  The scale of such interest is ACCEPTED MANUSCRIPT  ...  Nanoscopy based observation of single proteins, especially membrane proteins, and analyses of their chemical, conformational or folding modification are important to understand the in vivo functions of  ... 
doi:10.1016/j.matdes.2017.10.035 fatcat:ag3ko7n2pfgdlp6mwapvxrfsdy

Adult bone marrow mesenchymal and neural crest stem cells are chemoattractive and accelerate motor recovery in a mouse model of spinal cord injury

Virginie Neirinckx, Gulistan Agirman, Cécile Coste, Alice Marquet, Valérie Dion, Bernard Rogister, Rachelle Franzen, Sabine Wislet
2015 Stem Cell Research & Therapy  
following SCI, in the context of stem cell-based therapy but also in the early-phase clinical management of SCI patients.  ...  Results: We first observed that both cell types induced motor recovery in mice, and modified the inflammatory reaction in the lesion site.  ...  Foundation and by the Fonds Spéciaux à la Recherche of the University of Liège.  ... 
doi:10.1186/s13287-015-0202-2 pmid:26530515 pmcid:PMC4632651 fatcat:f4smvkctyfagxnxup6b7iy4yfq

Nuclear and Radiological Emergencies: Biological Effects, Countermeasures and Biodosimetry

Elena Obrador, Rosario Salvador-Palmer, Juan I. Villaescusa, Eduardo Gallego, Blanca Pellicer, José M. Estrela, Alegría Montoro
2022 Antioxidants  
In the case of large-scale atomic or radiological events, the most ideal choice for triage, dose assessment and victim classification, is the utilization of global biodosimetry networks, in combination  ...  with the automation of strategies based on modular platforms.  ...  Furthermore, in practice, clinical evaluation faces restrictions for large scale screening, i.e., the need of uniquely prepared medical care workers or the low throughput due to the short time available  ... 
doi:10.3390/antiox11061098 pmid:35739995 pmcid:PMC9219873 fatcat:p4tvl4kyzfcsrabzmxds6pei6y

The Use of Gamma-H2AX as a Biodosimeter for Total-Body Radiation Exposure in Non-Human Primates

Christophe E. Redon, Asako J. Nakamura, Ksenia Gouliaeva, Arifur Rahman, William F. Blakely, William M. Bonner, Eric J. Bernhard
2010 PLoS ONE  
Methods and Findings: We evaluated immunocytofluorescence-based quantitation of c-H2AX foci as a biodosimeter of total-body radiation exposure ( 60 Co c-rays) in a rhesus macaque (Macaca mulatta) model  ...  These results also demonstrate that the use of a high throughput c-H2AX biodosimeter would be useful for days post-exposure in applications like large-scale radiological events or radiation therapy.  ...  Andre Dubois (Dept. of Medicine, USUHS) for his generous donation of unirradiated macaque whole blood (used here for ex-vivo radiation studies). We also thank Dr. O.  ... 
doi:10.1371/journal.pone.0015544 pmid:21124906 pmcid:PMC2990755 fatcat:nonle42wfzap7bottdp4jbdnqq

Overview of physical dosimetry methods for triage application integrated in the new European network RENEB

François Trompier, Christopher Burbidge, Céline Bassinet, Marion Baumann, Emanuela Bortolin, Cinzia De Angelis, Jonathan Eakins, Sara Della Monaca, Paola Fattibene, Maria Cristina Quattrini, Rick Tanner, Albrecht Wieser (+1 others)
2016 International Journal of Radiation Biology  
Conclusions: Physically-based dosimetry techniques present high capacity, new possibilities for accident dosimetry, especially in the case of large-scale events.  ...  dose assessment capacity for large-scale radiation/nuclear accidents.  ...  The authors report no conflicts of interest. The authors alone are response for the content and writing of the paper.  ... 
doi:10.1080/09553002.2016.1221545 pmid:27584947 fatcat:sqmgmsv3djb7hi6udnmp2la7pe

Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System

Eric S. Diffenderfer, Ioannis I. Verginadis, Michele M. Kim, Khayrullo Shoniyozov, Anastasia Velalopoulou, Denisa Goia, Mary Putt, Sarah Hagan, Stephen Avery, Kevin Teo, Wei Zou, Alexander Lin (+10 others)
2020 International Journal of Radiation Oncology, Biology, Physics  
We have designed and dosimetrically validated a FLASH-PRT system with accurate control of beam flux on a millisecond time scale and online monitoring of the integral and dose delivery time structure.  ...  Acknowledgments Institutional funds were provided by the Department of Radiation Oncology, University of Pennsylvania.  ...  vivo.  ... 
doi:10.1016/j.ijrobp.2019.10.049 pmid:31928642 pmcid:PMC7325740 fatcat:2uqcehfto5fmte4sdlk2igvgma

IR-based Traceability Recovery as a Plugin – An Industrial Case Study

Markus Borg
2011 unpublished
Early studies have shown promising results, but no large-scale in vivo evaluations have been made.  ...  Our goal is to develop an IR-based traceability recovery plugin to this tool.  ...  EVALUATE APPROACH IN INDUSTRIAL CASE STUDY The aim of this study will be to evaluate how well the IR-based approach to traceability recovery works in a real industrial setting.  ... 
doi:10.14236/ewic/fdia2011.3 fatcat:4qghxiwj5zhlzgpeh5772q4w5a

Measurement and evaluation of specific absorption rate and temperature elevation caused by an artificial hip joint during MRI scanning

Youngseob Seo, Zhiyue J. Wang
2021 Scientific Reports  
Experimental measurement in conjunction with computational modeling was used to evaluate the risk of biological tissue injury from the RF heating of artificial hip joints by obtaining both specific absorption  ...  We have demonstrated the feasibility of evaluating RF heating of metallic hip joints during MRI scans.  ...  Finally, we thank Young-Hee Lee for calibration of FBG-based temperature sensors.  ... 
doi:10.1038/s41598-020-80828-7 pmid:33441883 fatcat:2doynvhth5bwdngdyh2yytivhm

Stable isotope ratio analysis for authentication of red yeast rice

Matteo Perini, Gianfranco Carbone, Federica Camin
2017 Talanta: The International Journal of Pure and Applied Analytical Chemistry  
Acknowledgements The Autonomous Province of Bolzano, Department of Innovation, Research and University (Decision n. 1472, 07.10.2013) is gratefully acknowledged for financial support and Ecoresearch srl  ...  most significant large-scale drivers for the isotopic composition of Italian EVOOs.  ...  ex-vivo formation.  ... 
doi:10.1016/j.talanta.2017.05.057 pmid:28738573 fatcat:uz7gr4edhvfqnmodaoaunxfswa

Designing multifunctional quantum dots for bioimaging, detection, and drug delivery

Pavel Zrazhevskiy, Mark Sena, Xiaohu Gao
2010 Chemical Society Reviews  
Possessing versatile surface chemistry and superior optical features, QDs have found initial use in a variety of in vitro and in vivo applications.  ...  The emerging field of bionanotechnology aims at revolutionizing biomedical research and clinical practice via introduction of nanoparticle-based tools, expanding capabilities of existing investigative,  ...  Acknowledgments This work was supported in part by NIH (R01CA131797, R01CA140295), NSF, and the Department of Bioengineering at the University of Washington.  ... 
doi:10.1039/b915139g pmid:20697629 pmcid:PMC3212036 fatcat:e5poqguprvg7llmkd7lpztx32e
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