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Improving data access efficiency by using a tagless access buffer (TAB)

A. Bardizbanyan, P. Gavin, D. Whalley, M. Sjalander, P. Larsson-Edefors, S. McKee, P. Stenstrom
2013 Proceedings of the 2013 IEEE/ACM International Symposium on Code Generation and Optimization (CGO)  
We describe the implementation and use of a tagless access buffer (TAB) that greatly improves data access energy efficiency while slightly improving performance.  ...  tag checks or data translation lookaside buffer (DTLB) lookups for TAB accesses; and (3) reducing DTLB lookups when transferring data between the L1D and the TAB.  ...  This research was supported in part by NSF grants CNS-0964413 and CNS-0915926, and in part by grant 2009-4566 of the Swedish Research Council.  ... 
doi:10.1109/cgo.2013.6495003 dblp:conf/cgo/BardizbanyanGWSLMS13 fatcat:4gkhasalirbyvbc3gf6y332s4m

Redesigning a tagless access buffer to require minimal ISA changes

Carlos Sanchez, Peter Gavin, Daniel Moreau, Magnus Själander, David Whalley, Per Larsson-Edefors, Sally A. McKee
2016 Proceedings of the International Conference on Compilers, Architectures and Synthesis for Embedded Systems - CASES '16  
Our prior work reduced data cache energy via a tagless access buffer (TAB) that sits at the top of the cache hierarchy.  ...  Together, the new TAB, L1D, and DTLB use 22% less energy than a TAB-less hierarchy, and the TAB system decreases execution time by 1.7%.  ...  Our prior work introduces a small, power-efficient structure -the tagless access buffer (TAB) -into the cache hierarchy to reduce L1D and DTLB energy dissipation [3] .  ... 
doi:10.1145/2968455.2968504 dblp:conf/cases/SanchezGMSWLM16 fatcat:hmmqgwqj6nadrjabo4q4n2l3om

Improving Data Access Efficiency by Using Context-Aware Loads and Stores

Alen Bardizbanyan, Magnus Själander, David Whalley, Per Larsson-Edefors
2015 Proceedings of the 16th ACM SIGPLAN/SIGBED Conference on Languages, Compilers and Tools for Embedded Systems 2015 CD-ROM - LCTES'15  
Memory operations have a significant impact on both performance and energy usage even when an access hits in the level-one data cache (L1 DC).  ...  We describe a set of techniques where the compiler enhances load and store instructions so that they can be executed with fewer stalls and/or enable the L1 DC to be accessed in a more energy-efficient  ...  This research was supported in part by the Swedish Research Council grant 2009-4566 and the US National Science Foundation grants CNS-0964413 and CNS-0915926.  ... 
doi:10.1145/2670529.2754960 dblp:conf/lctrts/BardizbanyanSWL15 fatcat:rp5cnyxtjbhjxeohqjyxs5uwnm

Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate

Bence György, Elise J. Meijer, Maryna V. Ivanchenko, Kelly Tenneson, Frederick Emond, Killian S. Hanlon, Artur A. Indzhykulian, Adrienn Volak, K. Domenica Karavitaki, Panos I. Tamvakologos, Mark Vezina, Vladimir K. Berezovskii (+7 others)
2019 Molecular Therapy: Methods & Clinical Development  
In a mouse model of Usher syndrome type 3A deafness (gene CLRN1), we use AAV9-PHP.B encoding Clrn1 to partially rescue hearing.  ...  Hereditary hearing loss often results from mutation of genes expressed by cochlear hair cells.  ...  This work was supported by a Lefler Center postdoctoral fellowship (to B.G.); NIH grants DC002281 and DC016932 (to D.P.C.)  ... 
doi:10.1016/j.omtm.2018.11.003 pmid:30581889 pmcid:PMC6297893 fatcat:6wo5tjg5xbcerdjl4mcnsqt7vm

Dynamic Compilation for Functional Programs [article]

Martin Grabmüller, Technische Universität Berlin, Technische Universität Berlin, Peter Pepper
The goal of the optimization is increased run-time efficiency, which is obtained by compiler-directed elimination of programming language abstractions.  ...  using dynamic transformation techniques.  ...  by a sophisticated code buffer manager.  ... 
doi:10.14279/depositonce-2180 fatcat:kbkxfmchofalxj33x2uspnq7gq

Application of nuclear magnetic resonance spectroscopy for the evaluation of folding variability in calcium binding proteins and its implications in food allergies

Federica <1978> Casadei, Mauro Andrea Cremonini
This value is calculated from crystallographic data by using a spherical probe the size of a water molecule.  ...  It can also be used for buffer exchange -a protein dissolved in a sodium acetate buffer, pH 4.8, can be applied to a gel filtration column that has been equilibrated with tris buffer, pH 8.0.  ...  C. 1 2 3 4 5 6 7 8 9 / / 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 A.  ... 
doi:10.6092/unibo/amsdottorato/430 fatcat:u5fspr3i3nds3a4vg254escgny

Biochemische und immunologische Charakterisierung der PR-10 Allergene Cor a 1 aus Hasel und Dau c 1 aus Karotte : Liganden, Stabilität, neue Isoallergene

Thessa Jacob
Trotzdem weisen sowohl Cor a 1.0401 als auch Bet v 1.0101 eine sehr hohe Spezifität auf und binden nur ihren eigenen Liganden.  ...  Die Struktur von Cor a 1.0401, welche durch multidimensionale NMR-Spektroskopie bestimmt wurde, ermöglichte eine genauere Charakterisierung der Bindungstasche.  ...  Open access funding enabled and organized by Projekt DEAL.  ... 
doi:10.15495/epub_ubt_00005423 fatcat:ubrslnnjfbgq5akzrtgmyoyrsq