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Improved Precision in the Measurement of Longitudinal Global and Regional Volumetric Changes via a Novel MRI Gradient Distortion Characterization and Correction Technique [chapter]

Vladimir S. Fonov, Andrew Janke, Zografos Caramanos, Douglas L. Arnold, Sridar Narayanan, G. Bruce Pike, D. Louis Collins
2010 Lecture Notes in Computer Science  
This work proposes a method to characterize and compensate for these distortions using a novel image processing technique relying on the image acquisition of a phantom with known geometrical dimensions  ...  Reducing measurement variability in MRI-based morphometric analysis of human brain structures will increase statistical power to detect changes between groups and longitudinally over time in individual  ...  In the current work we expand the proposed technique to compensate for the gradient-induced distortions and demonstrate its effect on the precision of the longitudinal volumetric analysis.  ... 
doi:10.1007/978-3-642-15699-1_34 fatcat:f7zln225ubddnl3qi62xlg3y2y

Magnetic resonance temperature imaging

B. Denis de Senneville, B. Quesson, C. T. W. Moonen
2005 International Journal of Hyperthermia  
Continuous, real-time 3D temperature mapping during a hyperthermic procedure may provide enhanced safety by visualizing temperature maps in and around the treated region, improved efficiency by adapting  ...  Noninvasive mapping of temperature changes can be achieved with MRI, and may be based on temperature dependent MRI parameters.  ...  ( 0 . 0 5T) and high field (≥1.5T), it remains necessary to improve volumetric coverage of the region of interest in mobile tissues, to precisely characterize local distribution of the temperature in  ... 
doi:10.1080/02656730500133785 pmid:16147437 fatcat:ozaxjct3ajaspjvqfis5c2ksja

A Novel Method for High-Dimensional Anatomical Mapping of Extra-Axial Cerebrospinal Fluid: Application to the Infant Brain

Mahmoud Mostapha, Sun Hyung Kim, Alan C. Evans, Stephen R. Dager, Annette M. Estes, Robert C. McKinstry, Kelly N. Botteron, Guido Gerig, Stephen M. Pizer, Robert T. Schultz, Heather C. Hazlett, Joseph Piven (+3 others)
2020 Frontiers in Neuroscience  
The quantitative analysis of local EA-CSF was applied to a dataset of typically developing infants with longitudinal MRI scans from 6 to 24 months of age.  ...  Statistical analysis of local EA-CSF revealed several novel findings: several regions of the cerebral cortex showed reductions in EA-CSF from 6 to 24 months of age, and specific regions showed higher local  ...  The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit  ... 
doi:10.3389/fnins.2020.561556 pmid:33132824 pmcid:PMC7561674 fatcat:g3zbexu3ijaj3pt772uzganh2e

Traumatic brain injury: a comparison of diffusion and volumetric magnetic resonance imaging measures

N J Bourke, M Yanez Lopez, P O Jenkins, S De Simoni, J H Cole, P Lally, E Mallas, H Zhang, D J Sharp
2021 Brain Communications  
Here we compare the performance of diffusion tensor imaging, neurite orientation dispersion and density-imaging and volumetric measures of brain atrophy in the identification of white matter abnormalities  ...  Thirty patients with moderate-severe traumatic brain injury in the chronic phase and 20 age-matched controls had T1-weighted and diffusion MRI.  ...  Conflict of interest statement Nothing to report.  ... 
doi:10.1093/braincomms/fcab006 pmid:33981994 pmcid:PMC8105496 fatcat:iiqueblp2vgjjat5lrnkulla4i

Longitudinal in vivo MRI in a Huntington's disease mouse model: Global atrophy in the absence of white matter microstructural damage

Jessica J. Steventon, Rebecca C. Trueman, Da Ma, Emma Yhnell, Zubeyde Bayram-Weston, Marc Modat, Jorge Cardoso, Sebastian Ourselin, Mark Lythgoe, Andrew Stewart, Anne E. Rosser, Derek K. Jones
2016 Scientific Reports  
Diffusion MRI is a powerful method for non-invasive characterization of tissue microstructure, and is a valuable addition to longitudinal designs.  ...  Previous studies have used MRI to characterise neuropathological changes in transgenic mouse models of HD 10,11 whereas in this work, we utilize a knock-in model where the genetic basis of HD is more precisely  ...  Acknowledgements We wish to thank Chris Von Ruhland at the Electron Microscopy Unit (Cardiff University) for preparation and processing of the EM sections and the Wellcome Trust for funding this work.  ... 
doi:10.1038/srep32423 pmid:27581950 pmcid:PMC5007531 fatcat:c3nhrnaygnc3znq2wgzqyxzzj4

Application of deep learning in detecting neurological disorders from magnetic resonance images: a survey on the detection of Alzheimer's disease, Parkinson's disease and schizophrenia

Manan Binth Taj Noor, Nusrat Zerin Zenia, M Shamim Kaiser, Shamim Al Mamun, Mufti Mahmud
2020 Brain Informatics  
Neuroimaging, in particular magnetic resonance imaging (MRI), has been playing an important role in understanding brain functionalities and its disorders during the last couple of decades.  ...  These cutting-edge MRI scans, supported by high-performance computational tools and novel ML techniques, have opened up possibilities to unprecedentedly identify neurological disorders.  ...  Acknowledgements The authors would like to thank the members of the acslab (http://www.acsla for valuable discussions.  ... 
doi:10.1186/s40708-020-00112-2 pmid:33034769 pmcid:PMC7547060 fatcat:vvnq3knq4rgfrcwov3yr2s3mk4

Dynamic patterns of cortical expansion during folding of the preterm human brain

Kara E. Garcia, Emma C. Robinson, Dimitrios Alexopoulos, Donna L. Dierker, Matthew F. Glasser, Timothy S. Coalson, Cynthia M. Ortinau, Daniel Rueckert, Larry A. Taber, David C. Van Essen, Cynthia E. Rogers, Christopher D. Smyser (+1 others)
2018 Proceedings of the National Academy of Sciences of the United States of America  
This information provides a detailed picture of dynamic changes in cortical growth, connecting what is known about patterns of development at the microscopic (cellular) and macroscopic (folding) scales  ...  Physical models suggest that relatively rapid growth of the cortical gray matter helps drive this folding, and structural data suggest that growth may vary in both space (by region on the cortical surface  ...  This shift in focus -regularizing the physical anatomical mesh instead of the abstract spherical mesh -offers a significant improvement for longitudinal registration using spherical techniques, which have  ... 
doi:10.1073/pnas.1715451115 pmid:29507201 pmcid:PMC5866555 fatcat:hkgoopgjkvb6nctid34upz3itq

Advanced MRI for cardiac assessment in mice [article]

Guido Buonincontri
2022 arXiv   pre-print
Volumetric measurements of ventricle size at each phase of the heart cycle (obtained with cine MRI) can be used as a sensitive measure for heart failure.  ...  The method includes cine and LGE MRI as well as a measure of mechanical strain in the myocardium with displacement encoding with stimulated echoes (DENSE) MRI and assessment of cellular metabolism with  ...  Adrian Carpenter and Dr. Stephen Sawiak for their  ... 
arXiv:2201.03033v1 fatcat:e5du4j45jbac5o7kkbeevenmwa

Technical Aspects of in vivo Small Animal CMR Imaging

Hao Li, Alireza Abaei, Patrick Metze, Steffen Just, Qinghua Lu, Volker Rasche
2020 Frontiers in Physics  
Technical improvements have enabled the transfer of CMR to small animal research, and as such made this non-invasive technique available to provide insights into cardiac morphology, function, perfusion  ...  In preclinical research, small rodent animal models of human cardiovascular diseases are frequently used to investigate the basic underlying mechanism of normal and abnormal cardiac function and for monitoring  ...  ACKNOWLEDGMENTS The authors would like to thank the Ulm University Center for Translational Imaging MoMAN for its support.  ... 
doi:10.3389/fphy.2020.00183 fatcat:yqs3yoqyqvfefjbfjfgtzhmloi

Front Matter: Volume 9784

2016 Medical Imaging 2016: Image Processing  
of tissue phase mapping MRI [9784-3] 9784 05 Automatic detection of cardiovascular risk in CT attenuation correction maps in Rb-82 PET/CTs [9784-4] 9784 06 Combining the boundary shift integral and tensor-based  ...  0N A novel structured dictionary for fast processing of 3D medical images, with application to computed tomography restoration and denoising [9784-22] SESSION 6 SHAPE 9784 0P Landmark based shape analysis  ...  user interface for the identification of bone profiles in CT images via extended Hough transform Improved registration of DCE-MR images of the liver using a prior segmentation of the region of interest  ... 
doi:10.1117/12.2240619 fatcat:kot6cogf4rf6dcjhkzdrr5gahi

Magnetic Resonance Biomarkers in Radiation Oncology

Kiaran P McGee, Ken Hwang, Daniel C Sullivan, John Kurhanewicz, Yanle Hu, Jihong Wang, Wen Li, Josef Debbins, Eric Paulson, Jeffrey R Olsen, Chia-Ho Hua, Lizette Warner (+4 others)
2021 Medical Physics (Lancaster)  
A magnetic resonance (MR) biologic marker (biomarker) is a measurable quantitative characteristic that is an indicator of normal biological and pathogenetic processes or a response to therapeutic intervention  ...  and improve clinical outcomes.  ...  CONFLICTS OF INTEREST The members of TG294 listed below attest that they have no potential Conflicts of Interest related to the subject matter or materials presented in this document.  ... 
doi:10.1002/mp.14884 pmid:33864283 pmcid:PMC8361924 fatcat:ovov3g4weze43op2jixcftuepq

Advances in Multimodal Data Fusion in Neuroimaging: Overview, Challenges, and Novel Orientation

Yu-Dong Zhang, Zhengchao Dong, Shui-Hua Wang, Xiang Yu, Xujing Yao, Qinghua Zhou, Hua Hu, Min Li, Carmen Jiménez-Mesa, Javier Ramirez, Francisco J. Martinez, Juan Manuel Gorriz
2020 Information Fusion  
We provide a review that encompasses (1) an overview of current challenges in multimodal fusion (2) the current medical applications of fusion for specific neurological diseases, (3) strengths and limitations  ...  Neuroimaging fusion can achieve higher temporal and spatial resolution, enhance contrast, correct imaging distortions, and bridge physiological and cognitive information.  ...  Distortion correction An MRI machine uses a static, homogenous, external magnetic field B0, a radio-frequency magnetic field B1, and three orthogonal gradient fields.  ... 
doi:10.1016/j.inffus.2020.07.006 pmid:32834795 pmcid:PMC7366126 fatcat:3cmhcplb5bf2fgpx3kukifbj74

High-resolution MRI detects cartilage swelling at the early stages of experimental osteoarthritis

E. Calvo, I. Palacios, E. Delgado, J. Ruiz-Cabello, P. Hernández, O. Sánchez-Pernaute, J. Egido, G. Herrero-Beaumont
2001 Osteoarthritis and Cartilage  
The measurement of cartilage thickness variations with MRI can be used to follow the course of OA and to evaluate the potential beneficial effect of novel therapies.  ...  Conclusion: The focal increase in cartilage thickness is one of the earliest measurable changes in OA and preceeds subchondral bone remodeling.  ...  To evaluate the potential beneficial effect of novel therapies with disease-modifying activities it is essential to quantitatively monitor the early changes in OA, and MRI is a useful technique that can  ... 
doi:10.1053/joca.2001.0413 pmid:11467895 fatcat:finf4dvoxbh6narxfoatxs4xkq

Alterations in cortical thickness and structural connectivity are associated with symptom severity in bulimia nervosa [article]

Margaret L Westwater, Jakob Seidlitz, Kelly MJ Diederen, Sarah Fischer, James C Thompson
2017 bioRxiv   pre-print
Our findings offer novel insight into CT alterations in BN and further suggest that the combination of CT and structural connectivity measures may be sensitive to individual differences in BN symptom severity  ...  This study examined whether changes in cortical thickness (CT) scaled with BN symptom severity in a sample of 33 adult women (n = 10 BN; n = 5 EDNOS-BN).  ...  Acknowledgements: We would like to thank the participants for their time and commitment to this study. The authors declare that there is no conflict of interest.  ... 
doi:10.1101/127910 fatcat:cyvqkcxrpbeolg3xlbyysi2ggy

Evaluation of a PEGylated Fibroblast Growth Factor 21 Variant Using Novel Preclinical Magnetic Resonance Imaging and Magnetic Resonance Elastography in a Mouse Model of Nonalcoholic Steatohepatitis

Haiying Tang, Jiahui Li, Bradley Zinker, Stephanie Boehm, Amy Mauer, Sandra Rex‐Rabe, Kevin J. Glaser, Matthew Fronheiser, Thomas Bradstreet, Yasuhiko Nakao, Thomas Petrone, Adrienne Pena (+8 others)
2022 Journal of Magnetic Resonance Imaging  
This study assessed the longitudinal effects of fibroblast growth factor 21 variant (polyethylene glycol [PEG]-FGF21v) on MRI-HFF and MRE-SS in a NASH mouse model. Preclinical.  ...  Regions of interest for MRI-HFF and MRE-SS were delineated by J.L. and H.T. (>5 years of experience each). Fibrosis and steatosis were measured histologically after picrosirius red and H&E staining.  ...  The MRE pulse programming on the 7T Bruker MRI system was provided by Mark Mattingly and Saaussan Madi who were employees of Bruker Biospin at the time of the study.  ... 
doi:10.1002/jmri.28077 pmid:35092323 fatcat:jc4qomqmrraqzdlcrtbea3fsru
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