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Implementation of the Department of Veterans Affairs' first point-of-care clinical trial

L. D'Avolio, R. Ferguson, S. Goryachev, P. Woods, T. Sabin, J. O'Neil, C. Conrad, J. Gillon, J. Escalera, M. Brophy, P. Lavori, L. Fiore
2012 JAMIA Journal of the American Medical Informatics Association  
The first pilot of a point-of-care clinical trial (POCCT), adding randomization and other study processes to an electronic medical record (EMR) system, was launched to compare the effectiveness of two  ...  Materials and Methods Existing functionalities of the Veterans Affairs (VA) computerized patient record system (CPRS)/veterans health information systems and technology architecture (VISTA) were modified  ...  They also wish to thank the VISN 1 chief informatics officer, Jason Atkins, Scott DuVall and the VINCI team, and Jack Bates of the VA Office of Information Technology Business Intelligence Product Line  ... 
doi:10.1136/amiajnl-2011-000623 pmid:22366293 pmcid:PMC3392864 fatcat:n7ok3nbhwvhtbgy7i5zwgbucp4

The Past, Present, and Future of Comparative Effectiveness Research in the US Department of Veterans Affairs

Joel Kupersmith, Alexander K. Ommaya
2010 American Journal of Medicine  
Many have pointed to the need for more comparative effectiveness research (CER) to aide in these decisions. The US Department of Veterans Affairs (VA) has a long history of conducting CER.  ...  In the future, the CER enterprise will move toward increased input from clinicians in research topic choice and enhanced consideration of other methodologies besides the randomized controlled trial.  ...  Ommaya, ScD, MA, has no financial arrangement or affiliation with a corporate organization or manufacturer of a product discussed in this article.  ... 
doi:10.1016/j.amjmed.2010.10.002 pmid:21184864 fatcat:kr34jywb2beijnk3tjqmksnicm

A hybrid type I trial to increase Veterans' access to insomnia care: study protocol for a randomized controlled trial

Adam D. Bramoweth, Anne Germain, Ada O. Youk, Keri L. Rodriguez, Matthew J. Chinman
2018 Trials  
Uptake of a briefer, more primary-care-friendly treatment into routine clinical care in Veterans Affairs (VA) primary care settings, where insomnia is typically first recognized and diagnosed, may effectively  ...  To identify potential implementation factors, individual interviews are conducted with the Veterans who participate in the clinical trial, as well as VA primary care providers and nursing staff.  ...  The views expressed are those of the authors and do not necessarily represent the views of the US Department of Veterans Affairs or the United States Government.  ... 
doi:10.1186/s13063-017-2437-y pmid:29373993 pmcid:PMC5787269 fatcat:cqle6ogrqjaypio3jbey2fss54

Improving Veteran Access to Integrated Management of Back Pain (AIM-Back): Protocol for an Embedded Pragmatic Cluster-Randomized Trial

Steven Z George, Cynthia J Coffman, Kelli D Allen, Trevor A Lentz, Ashley Choate, Adam P Goode, Corey B Simon, Janet M Grubber, Heather King, Chad E Cook, Francis J Keefe, Lindsay A Ballengee (+5 others)
2020 Pain medicine (Malden, Mass.)  
Background Coordinated efforts between the National Institutes of Health, the Department of Defense, and the Department of Veterans Affairs have built the capacity for large-scale clinical research investigating  ...  Design The Improving Veteran Access to Integrated Management of Back Pain (AIM-Back) trial is an embedded pragmatic cluster-randomized trial that will examine the effectiveness of two different care pathways  ...  of Defense, and the Department of Veterans Affairs (VA) has improved capacity for largescale clinical research focusing on nonpharmacologic treatment for pain by supporting a coordinating center and demonstration  ... 
doi:10.1093/pm/pnaa348 pmid:33313728 fatcat:xion62nypfdcpfm7s3k5htjdnq

Increasing access to clinical research using an innovative mobile recruitment approach: The (MoRe) concept

Danielle Beck, Aliya Asghar, Tawni Kenworthy-Heinige, Marcus R. Johnson, Cyenthia Willis, Alexandra S. Kantorowicz, Debra L. Condon, Grant D. Huang, Terence M. Keane, Pantel S. Vokonas, Dan Darroch, James LePage (+24 others)
2020 Contemporary Clinical Trials Communications  
The Department of Veterans Affairs (VA) Cooperative Studies Program (CSP) established a consortium of nine VA medical centers (VAMCs) called the Network of Dedicated Enrollment Sites (NODES).  ...  The implementation of MoRe by NODES as a recruitment strategy for MVP may be transferable to other VA clinical research studies, as well as to other healthcare settings executing similar clinical research  ...  The concept of the MoRe unit is transferrable to any research center and may be applied to a clinical trial within or outside the Department of Veterans Affairs Healthcare System.  ... 
doi:10.1016/j.conctc.2020.100623 pmid:32775763 pmcid:PMC7403877 fatcat:fee4avmehrdo7dl5xiqhbmrv5q

Data Sharing, Clinical Trials, and Biomarkers in Precision Oncology: Challenges, Opportunities, and Programs at the Department of Veterans Affairs

LD Fiore, MT Brophy, RE Ferguson, C Shannon, SJ Turek, K Pierce-Murray, S Ajjarapu, GD Huang, CSE Lee, PW Lavori
2017 Clinical Pharmacology and Therapeutics  
Cancer genomic research reveals that a similar cancer clinical phenotype (e.g., non-small cell lung cancer) can arise from various mutations in tumor DNA. Thus, organ of origin is not a defini-1  ...  The Department of Veterans Affairs continues to make progress in this area through the Point-of-Care research 9 and Precision Oncology 10 Programs whereby patients are randomized to minimal risk alternatives  ...  Clinical Oncology Availability of targeted therapy off label APOLLO 5 National Cancer Institute, Department of Veterans Affairs and the Department of Defense Tissue and data for biomarker development  ... 
doi:10.1002/cpt.660 pmid:28182272 pmcid:PMC5414893 fatcat:j2qxptrkbbgvlkyrnu75yj3jdm

Adapting and implementing Caring Contacts in a Department of Veterans Affairs emergency department: a pilot study protocol

Sara J. Landes, JoAnn E. Kirchner, John P. Areno, Mark A. Reger, Traci H. Abraham, Jeffery A. Pitcock, Mary J. Bollinger, Katherine Anne Comtois
2019 Pilot and Feasibility Studies  
Suicide among veterans is a problem nationally, and suicide prevention remains a high priority for the Department of Veterans Affairs (VA).  ...  The purpose of this study is to (1) adapt Caring Contacts for use in a VA emergency department, (2) conduct a pilot program at a single VA emergency department, and (3) create an implementation toolkit  ...  Acknowledgements The views expressed in this paper are those of the authors and do not necessarily reflect the position or policy of the United States Department of Veterans Affairs (VA), Veterans Health  ... 
doi:10.1186/s40814-019-0503-9 pmid:31624637 pmcid:PMC6785900 fatcat:5ndxzlnmrng7hnjjk2oljgcm2m

Effectiveness of Implementing a Collaborative Chronic Care Model for Clinician Teams on Patient Outcomes and Health Status in Mental Health

Mark S. Bauer, Christopher J. Miller, Bo Kim, Robert Lew, Kelly Stolzmann, Jennifer Sullivan, Rachel Riendeau, Jeffery Pitcock, Alicia Williamson, Samantha Connolly, A. Rani Elwy, Kendra Weaver
2019 JAMA Network Open  
Collaborative chronic care models (CCMs) have extensive randomized clinical trial evidence for effectiveness in serious mental illnesses, but little evidence exists regarding their feasibility or effect  ...  model; VA, US Department of Veterans Affairs.  ...  on clinical outcomes. 21 Given the dearth of data on implementing CCMs in mental health clinics, we partnered with the US Department of Veterans Affairs (VA) Office of Mental Health and Suicide Prevention  ... 
doi:10.1001/jamanetworkopen.2019.0230 pmid:30821830 pmcid:PMC6484628 fatcat:nwesilaembfwxkb4qmu5ctmr4a

Diabetes Quality Improvement in Department of Veterans Affairs Ambulatory Care Clinics: A group-randomized clinical trial

G. E. Reiber, D. Au, M. McDonell, S. D. Fihn
2004 Diabetes Care  
The views expressed are those of the authors and do not necessarily represent the views of the Department of Veteran Affairs.  ...  Acknowledgments -This research was supported by the Department of Veterans Affairs, Health Services Research and Development Service (SDR 96-002 and IIR 99-376).  ...  T he Department of Veterans Affairs (VA) is committed to providing quality health care to the 3.5 million veterans served by the VA.  ... 
doi:10.2337/diacare.27.suppl_2.b61 pmid:15113785 fatcat:53mfsxixsnelzes2wdiqtmkr7y

An evidence-based co-occurring disorder intervention in VA homeless programs: outcomes from a hybrid III trial

David A. Smelson, Matthew Chinman, Gordon Hannah, Thomas Byrne, Sharon McCarthy
2018 BMC Health Services Research  
Funding All of the work for this grant including the design, data collection, analysis, interpretation of the data, and writing of the manuscript are funded by a grant from the Health Services Research  ...  and Development Quality Enhancement Research Initiative, "MISSION-Vet HUD-VASH Implementation Study" (SDP 11-240).  ...  management services from the Department of Veteran Affairs [2] .  ... 
doi:10.1186/s12913-018-3123-9 pmid:29728148 pmcid:PMC5935954 fatcat:cnv3olmtdzep3lv2lozxjymn6u

Department of Veterans Affairs Hypertension Meeting : A Proposal for Improved Care

H. M. Perry, E. D. Freis, E. D. Frohlich
2000 Hypertension  
A major invitational hypertension meeting was hosted by the Department of Veterans Affairs (VA) in Washington, DC, on May 26 to 28, 1999.  ...  The meeting was closed with 6 general recommendations for improving the care of hypertensive patients. (Hypertension. 2000;35:853-857.)  ...  O n May 26 to 28, 1999, the Department of Veterans Affairs (VA) held a major invitational hypertension meeting in Washington, DC, entitled "Improvement in the Management of Hypertension in 2000 and Beyond  ... 
doi:10.1161/01.hyp.35.4.853 pmid:10775550 fatcat:5wn27vq6ejgxzpwiobatcffnje

An initiative using informatics to facilitate clinical research planning and recruitment in the VA health care system

Kandi E. Velarde, Jennifer M. Romesser, Marcus R. Johnson, Daniel O. Clegg, Olga Efimova, Steven J. Oostema, Jeffrey S. Scehnet, Scott L. DuVall, Grant D. Huang
2018 Contemporary Clinical Trials Communications  
The Department of Veterans Affairs (VA) has a strong history of clinical and epidemiological research with over four decades of data collected from Veterans it has served nationwide.  ...  trial study teams and facilitation of clinical trial research within a large, integrated healthcare system.  ...  The United States Department of Veterans Affairs (VA) has a strong history of clinical and epidemiological research with over four decades of data collected nationwide from Veterans it has served [17]  ... 
doi:10.1016/j.conctc.2018.07.001 pmid:30035242 pmcid:PMC6052195 fatcat:hbmwgcv25zhonc4q6abtmbrm2y

Gene-based prescribing is here – are providers ready?

Leland E. Hull, Lisa Soleymani Lehmann, Julie A. Lynch
2019 American Journal of Medicine  
JAL receives support from the PRIME Care (PRecision Medicine In MEntal Health Care) Program Grant (SDR 16-348) from the US Department of Veterans Affairs Health Services Research & Development Service  ...  Funding: LEH is supported by the Department of Veterans Affairs Office of Academic Affiliations Advanced Fellowship Program in Health Services Research, the Center for Healthcare Organization and Implementation  ... 
doi:10.1016/j.amjmed.2019.02.036 pmid:30871924 fatcat:fumvouhlb5e7bjisc2ltfiv7rm

Care Outcomes for Chiropractic Outpatient Veterans (COCOV): a single-arm, pragmatic, pilot trial of multimodal chiropractic care for U.S. veterans with chronic low back pain

Cynthia R. Long, Stacie A. Salsbury, Robert D. Vining, Anthony J. Lisi, Lance Corber, Elissa Twist, Thad Abrams, Robert B. Wallace, Christine M. Goertz
2022 Pilot and Feasibility Studies  
Conclusions We demonstrated the feasibility of participant recruitment, retention, and electronic data collection for conducting a pragmatic clinical trial of chiropractic care in a Veterans Health Administration  ...  care for pain management of veterans with chronic low back pain.  ...  Norton, DC, for their services as the doctors of chiropractic in this study.  ... 
doi:10.1186/s40814-022-01008-0 pmid:35256010 pmcid:PMC8900358 fatcat:7ivxsdixfjgpxmxki3rgzmfpgu

Current use and costs of electronic health records for clinical trial research: a descriptive study

Kimberly A. Mc Cord, Hannah Ewald, Aviv Ladanie, Matthias Briel, Benjamin Speich, Heiner C. Bucher, Lars G. Hemkens
2019 CMAJ Open  
Overall, in most of the trials (158 [83.6%]), the outcome (including many of the most patient-relevant clinical outcomes, from unscheduled hospital admission to death) was measured with the use of EHRs  ...  Randomized controlled trials are frequently and increasingly conducted with the use of EHRs, but mainly as part of the intervention.  ...  Five trials (29%) used the EHR of a US Department of Veterans Affairs or affiliated facility.  ... 
doi:10.9778/cmajo.20180096 pmid:30718353 pmcid:PMC6375253 fatcat:5l4qwwm3kbccnpnpwxv5f4ky7u
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