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Immunization and Targeted Destruction of Networks using Explosive Percolation
2016
Physical Review Letters
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A new method ('explosive immunization' (EI)) is proposed for immunization and targeted destruction of networks. ...
It combines the explosive percolation (EP) paradigm with the idea of maintaining a fragmented distribution of clusters. ...
VP2-2014-043) and from Horizon2020 (Grant No. 642563 -COSMOS). ...
doi:10.1103/physrevlett.117.208301
pmid:27886508
fatcat:jqvsxnrtbvgs5cryp6uzxtvccu
Influencer identification in dynamical complex systems
[article]
2019
arXiv
pre-print
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In particular, we first discuss the problem of finding the minimal number of nodes whose removal would breakdown the network (i.e., the optimal percolation or network dismantle problem), and then survey ...
The integrity and functionality of many real-world complex systems hinge on a small set of pivotal nodes, or influencers. ...
In Section 3, we discuss the progresses in optimal percolation using collective influence, optimal decycling, explosive percolation and large deviations of percolation in details. ...
arXiv:1907.13017v3
fatcat:5lw7uebqqbht5bn5tjamjn7jau
Explosive phenomena in complex networks
2019
Advances in Physics
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2019 pre-print arXiv:1907.09957v1 fatcat:rj4erx5fsrckzlr76swxlt7zoq
Models of explosive synchronization provide an analytic framework for the dynamics of abrupt transitions and reveal the interplay between the distribution in natural frequencies and the network structure ...
The emergence of large-scale connectivity and synchronization are crucial to the structure, function and failure of many complex socio-technical networks. ...
ACKNOWLEDGMENTS We gratefully acknowledge support from funding agencies and the reviewers of this manuscript. In particular RMD acknowledges support from the U. ...
doi:10.1080/00018732.2019.1650450
fatcat:ggtqf675qjahrequpgz5gs44xu
Theories for influencer identification in complex networks
[article]
2018
arXiv
pre-print
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In social and biological systems, the structural heterogeneity of interaction networks gives rise to the emergence of a small set of influential nodes, or influencers, in a series of dynamical processes ...
Finally, we present some applications of influencer identification in diverse real-world systems, including online social platforms, scientific publication, brain networks and socioeconomic systems. ...
Acknowledgement We acknowledge funding from NIH-NIBIB 1R01EB022720, NIH-NCI U54CA137788 / U54CA132378 and nsf-iis 1515022. ...
arXiv:1707.01594v2
fatcat:j6je622mxffyxpgznciqdavo74
Challenges in network science: Applications to infrastructures, climate, social systems and economics
2012
The European Physical Journal Special Topics
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Network theory has become one of the most visible theoretical frameworks that can be applied to the description, analysis, understanding, design and repair of multi-level complex systems. ...
Complex networks occur everywhere, in man-made and human social systems, in organic and inorganic matter, from nano to macro scales, and ...
and robustness using scaling and percolation approaches. ...
doi:10.1140/epjst/e2012-01695-x
fatcat:poyouxltpbcyflrcwaslew2dti
The Islamic State Threat to Western Homeland Security
2017
Journal of Political Sciences & Public Affairs
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Likewise we renew our call to the muwahhidin in Europe and the disbelieving West and elsewhere, to target the crusaders in their own lands and wherever they are found. ...
We will argue before Allah against any Muslim who has the ability to shed a single drop of crusader blood but does not do so, whether with an explosive device, a bullet, a knife, a car, a rock, or even ...
42 Thomas Joscelyn, "The Future of Counterterrorism: Addressing the Evolving Threat to Domestic Security" February 28, 2017 Foundation for the Defense of Democracies accessed at: http://docs.house.gov/ ...
doi:10.4172/2332-0761.1000259
fatcat:xr5hvpxnqzfsxdewudzwqysokm
Multilayer networks
2014
Journal of Complex Networks
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In this paper, we discuss the history of multilayer networks (and related concepts) and review the exploding body of work on such networks. ...
The origins of such efforts date back several decades and arose in multiple disciplines, and now the study of multilayer networks has become one of the most important directions in network science. ...
explosion of papers on multilayer networks has produced an equally immense explosion of disparate terminology, and the lack of a consensus (or even generally accepted) set of terminology and mathematical ...
doi:10.1093/comnet/cnu016
fatcat:gkvuniqrdbgkpn22t7fkt7vdke
Immunology for physicists
1997
Reviews of Modern Physics
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Sulzer and D. Sherrington for their careful comments on a draft of this manuscript, and B. Goldstein for help with the illustrations. ...
Much of the work reported here was done in collaboration with Rob De Boer, Avidan Neumann, and Lee Segel. ...
In the presence of percolation and large-scale fluctuations it is difficult to envision how immune memory might be maintained by a network. ...
doi:10.1103/revmodphys.69.1219
fatcat:w3dzlfuuqzdq5e27me7yb5u2ka
The structure and dynamics of multilayer networks
2014
Physics reports
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the time-varying and multilayer nature of networks. ...
redefinition of the basic structural measures, to understanding how the multilayer nature of the network affects processes and dynamics. ...
132
Nation 2 Nation 1 Nation 1 SatCom Nation 1 UHF Network1 Nation 1 VHF Network Nation 1 UHF Network2 Nation 2 UHF Network Furthermore, a part of the material quoted in our presentation was taken from ...
doi:10.1016/j.physrep.2014.07.001
pmid:32834429
pmcid:PMC7332224
fatcat:5y6wdkop2nd75kwnla4by2icqy
Harnessing Novel Imaging Approaches to Guide HIV Prevention and Cure Discoveries—A National Institutes of Health and Global HIV Vaccine Enterprise 2017 Meeting Report
2018
AIDS Research and Human Retroviruses
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In the HIV/SIV field, imaging has provided key insights into mucosal viral transmission, local and systemic virus spread, host-virus dynamics, and chronic inflammation/immune activation and the resultant ...
The meeting covered applications of imaging in studies of early events and pathogenesis, reservoirs, and cure, as well as in vaccine development. ...
The workshop was funded by the Global HIV Vaccine Enterprise and with federal funds from the National Institute of Allergies and Infectious Diseases, National Institutes of Health, Department of Health ...
doi:10.1089/aid.2017.0216
pmid:29145733
pmcid:PMC5824657
fatcat:nwmpbk7y2jfrvfgd2f74m4fbqy
Coevolution spreading in complex networks
2019
Physics reports
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To uncover the dynamical mechanisms, the evolving spatiotemporal patterns and critical phenomena of networked coevolution spreading are extremely important, which provide theoretical foundations for us ...
In this review, we introduce recent progress in the study of coevolution spreading dynamics, emphasizing the contributions from the perspectives of statistical mechanics and network science. ...
By using a generalized percolation theory, the fraction of nodes infected by each epidemic and both epidemics in the final state can be obtained. ...
doi:10.1016/j.physrep.2019.07.001
pmid:32308252
pmcid:PMC7154519
fatcat:zvkfs3pdondvbnxpdd43mm4tne
From Metabolite to Metabolome: Metabolomics Applications in Plasmodium Research
2021
Frontiers in Microbiology
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Therefore, this review highlights the progress of metabolomics in malaria research, including metabolic mapping of Plasmodium vertebrate life cycle stages to investigate antimalarials mode of actions and ...
This improves the investigation of varied metabolic requirements during life stages or when following transmission to their hosts, and fulfills the demand for improved diagnostics and precise therapeutics ...
More recently, one rapid and easily to handle purification method for viable ring stage parasites using a combination of selective lysis property of Streptolysin-O and permeability of Percoll has been ...
doi:10.3389/fmicb.2020.626183
pmid:33505389
pmcid:PMC7829456
fatcat:zixjvxlvn5hdxke4qase7zmwma
AACR Cancer Progress Report 2013
2013
Clinical Cancer Research
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They operate, at least in part, by attaching to cancer cells expressing their target, flagging them for destruction by immune cells. ...
Widespread use of these new technologies has led to an explosion of genetic information about cancers of different types. ...
Immune system -A diffuse, complex network of interacting cells, cell products, and cell-forming tissues that protects the body from invading microorganisms and other foreign substances, destroys infected ...
doi:10.1158/1078-0432.ccr-13-2107
pmid:24045178
fatcat:hump63r4afczbby6cyxs74uj3a
Exploring the "Multiple-Hit Hypothesis" of Neurodegenerative Disease: Bacterial Infection Comes Up to Bat
2019
Frontiers in Cellular and Infection Microbiology
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This review will broadly explore the connections between bacterial infection, immune dysregulation, and CNS disorders. ...
Recent data has begun to demonstrate roles for these genes (PARK2, PINK1, and LRRK2) in modulating innate immune outcomes, suggesting that immune dysregulation may play an even more important role in neurodegeneration ...
Multiple studies have shown that macrophages use selective autophagy to tag and target a population (∼30%) of M. tuberculosis bacilli to autophagosomes. ...
doi:10.3389/fcimb.2019.00138
pmid:31192157
pmcid:PMC6546885
fatcat:pzyavbobx5hvrablkyxhivwqce
Structure and dynamics of molecular networks: A novel paradigm of drug discovery
2013
Pharmacology and Therapeutics
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The state-of-the-art use of chemical similarity, protein structure, protein-protein interaction, signaling, genetic interaction and metabolic networks in the discovery of drug targets is summarized. ...
It is shown how network techniques can help in the identification of single-target, edgetic, multi-target and allo-network drug target candidates. ...
Academy of Sciences, Szeged, Hungary) for the critical reading of Sections 1.3.3 and 3.6, respectively. ...
doi:10.1016/j.pharmthera.2013.01.016
pmid:23384594
pmcid:PMC3647006
fatcat:osjkz6kpr5gzxomqlyenla2fvq
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