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Identification of most influential co-occurring gene suites for gastrointestinal cancer using biomedical literature mining and graph-based influence maximization

Charles C. N. Wang, Jennifer Jin, Jan-Gowth Chang, Masahiro Hayakawa, Atsushi Kitazawa, Jeffrey J. P. Tsai, Phillip C.-Y. Sheu
2020 BMC Medical Informatics and Decision Making  
Our pipeline that uses text mining to identify objects and relationships to construct a graph and uses graph-based influence maximization to discover the most influential co-occurring genes presents a  ...  The entities and their associations can be used to construct a graph, and from which we can compute the sets of co-occurring genes that are the most influential based on an influence maximization algorithm  ...  We use biomedical literature mining and graph-based influence maximization, and integrated bioinformatics database to identifying influential genes for GI cancers.  ... 
doi:10.1186/s12911-020-01227-6 pmid:32883271 fatcat:kuhlzhnfvjczrn3vr7sg5cks5y

A Model of Selective Advantage for the Efficient Inference of Cancer Clonal Evolution [article]

Daniele Ramazzotti
2016 arXiv   pre-print
The pipeline combines state-of-the-art techniques for sample stratification, driver selection, identification of fitness-equivalent exclusive alterations and progression model inference.  ...  The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel Data Science and Machine Learning algorithms to infer models of cancer progression, and (iii  ...  They are extremely useful for visualizing gene set and pathway alterations across a set of cases, and for visually identifying trends, such as trends in mutual exclusivity or co-occurence between gene  ... 
arXiv:1602.07614v1 fatcat:3mdqck6ztnav7eea2xz4hl5xue

HGM 2010 Programme / Abstract

2010 The HUGO Journal  
The identification of an EYS mutation in a dog affected with retinal progressive atrophy would provide a useful model for establishing future therapies for retinitis pigmentosa.  ...  We would like to extend our utmost appreciation to them for all of their support.  ...  It then follows the identification and naming of ABCA13 as part of this family, its appearance in the biomedical literature and databases, its adoption for the mouse and rat orthologs as Abca13, and its  ... 
doi:10.1007/s11568-010-9143-0 fatcat:oykxd6u7snfi5o7m6tst7wi6yq

Health State Estimation [article]

Nitish Nag
2020 arXiv   pre-print
This work concludes by presenting this framework of combining the health state and personal graph model to perpetually plan and assist us in living life towards our goals.  ...  Life's most valuable asset is health. Continuously understanding the state of our health and modeling how it evolves is essential if we wish to improve it.  ...  Arxiv, 2020 • Development of rank system for cuisines based on user's preferences. • Weighting preferences based on event mining nutrition events. • Identification of ingredients commonly preferred, allowing  ... 
arXiv:2003.09312v1 fatcat:sm7vadoyerbf5gmeujvobcqop4

A sequential distance-based approach for imputing missing data: Forward Imputation

Nadia Solaro, Alessandro Barbiero, Giancarlo Manzi, Pier Alda Ferrari
2016 Advances in Data Analysis and Classification  
Breast cancer is the most prevalent cancer among women and the second leading cause of cancer death.  ...  The most important results gained were to demonstrate data mining and association rules algorithms are useful to identify a group of patients at higher risk of metastatic breast cancer.  ... 
doi:10.1007/s11634-016-0243-0 fatcat:yvrqlgllsbesbnvnzzci2egpl4

Angioma of the Cervical Spinal Cord

Leon Morris
1960 Radiology  
Small-portal shaped-beam therapy has been most useful in our hands for malignant disease in and about the head and neck (Fig. 1) and for breast cancer (Fig. 2).  ...  hereditary factor. the same is true, of course, for gene mutations.  ... 
doi:10.1148/75.5.785 pmid:13772851 fatcat:luofnr7s3ndcbadmknt2c3suum

Abstracts From the 23rd Annual Health Care Systems Research Network Conference, March 21–23, 2017, San Diego, California

2017 Journal of Patient-Centered Research and Reviews  
The Agency for Healthcare Research and Quality's Clinical Classifications Software tool was applied to identify prevalent conditions based on diagnosis codes attached to outpatient visits, laboratory and  ...  Urology patients had a mean of 7 chronic conditions. The 5 most common conditions were hypertension, hyperlipidemia, prostate disorders, gastroesophageal reflux disease and other.  ...  Providers used graphs (42%), trends (11%) and progress notes (8%) for patient education.  ... 
doi:10.17294/2330-0698.1583 pmid:31413982 pmcid:PMC6664347 fatcat:mupi235mffhrjgvpemph7zcubq

Responding to the challenge of cancer in Europe

2009 Australian and New Zealand Journal of Public Health  
The authors would like to thank their collaborators in the Division of Cancer Epidemiology and Prevention: Urszula Wojciechowska, Marta Manczuk, and Urszula Sulkowska for help in epidemiological analysis  ...  ; Lucja Didkowska, Mateusz Zatonski and Aleksandra Herbec for help in creating the English version of the text; and Joasia Szwechowicz and Ewa Tarnowska for help in editing the text and illustrations.  ...  The next phase of genetic discovery will be the identification of genes that contribute to the heritable component of the cause of cancer but do not have enough individual influence to account for families  ... 
doi:10.1111/j.1753-6405.2009.00395.x fatcat:xfssc74kqffzblasjvomf2pvsa

Abstract of 29th Regional Congress of the ISBT

2019 Vox Sanguinis  
Austria had for centuries a rich history of culture. The growing scientific community  ...  A high incidence of blood group A is seen in: pancreatic cancer A (42%), in gastric cancer A (43%), colorectal cancer A (39, 6%), breast cancer A (41%), cervical cancer A (43%) and ovarian cancer A (42%  ...  A high incidence of blood B is seen in multiple myeloma B (22%) and cervical cancer B (20%) versus B (16.2%) in the control group.  ... 
doi:10.1111/vox.12792 pmid:31173375 pmcid:PMC7169345 fatcat:vd4pqdm3g5cmfa7jqtsbwef56y

45th Annual SER Meeting Minneapolis, Minnesota June 27-30, 2012

2012 American Journal of Epidemiology  
The adjusted OR for prostate cancer associated with ever use of NSAIDs was 1.22 (95% CI: 0.88-1.69). There was no association with current use or duration of use.  ...  These findings provide no strong evidence for an association between NSAIDs use and prostate cancer risk. However, timing of exposure might be relevant.  ...  Severity and co-occurring developmental disabilities was associated with the frequency of dental visits.  ... 
doi:10.1093/aje/kws258 pmid:22684495 fatcat:oqvpk3zbtfbenmssr5uy2bwymm

Engaging Patients in Managing Their Health Care: Patient Perceptions of the Effect of a Total Joint Replacement Presurgical Class

2012 The Permanente Journal  
Acknowledgments The authors would like to thank May Lui, PhD; Julie Stern, MPH for their contribution to this manuscript. Leslie E Parker, ELS, provided editorial assistance.  ...  Acknowledgment Kathleen Louden, ELS, of Louden Health Communications provided editorial assistance.  ...  Introduction Despite its importance as the most commonly diagnosed noncutaneous cancer and the second leading cause of cancer death among men in the US, no definitive screening tool for prostate cancer  ... 
doi:10.7812/tpp/11-143 fatcat:jbq5iv3wlnhpndyymh5zdewqbq

Development of Web-Based Computer-Tailored Advice to Promote Physical Activity Among People Older Than 50 years

Denise A Peels, Maartje M van Stralen, Catherine Bolman, Rianne HJ Golsteijn, Hein de Vries, Aart N Mudde, Lilian Lechner
2012 Journal of Medical Internet Research  
For example, gene mutations which confer a high risk of breast cancer are important for carriers of those mutations but are present in only a small proportion of women who develop breast cancer.  ...  Low intake of fruit and vegetables is estimated to cause about 19% of gastrointestinal cancer, and about 31% of ischaemic heart disease and 11% of stroke worldwide.  ...  Member States by WHO Region and mortality stratum. b The combined effects of any group of risk factors in this table will often be less than the sum of their separate effects. … Data not available or  ... 
doi:10.2196/jmir.1742 pmid:22390878 pmcid:PMC3376526 fatcat:yzhhwypw4ngqno55ibgxdm7muu

Modern Applied Science, Vol. 2, No. 2, March 2008, all in one file

Editor MAS
2008 Modern Applied Science  
Acknowledgement The authors would like to acknowledge School of Mechanical Engineering, Universiti Sains Malaysia Engineering Campus and Universiti Sains Malaysia for their sponsorship of this work.  ...  In classification analysis, the decision tree model is one of the most popular models because it can expediently show the mining results by means of figure (tree structure) and suit decision-making for  ...  Most of the previous studies on workload allocation used exponential distribution for inter arrival and service time.  ... 
doi:10.5539/mas.v2n2p0 fatcat:iu3zrlcf7zbkjmsjror76rvyeq

Multivariate Markovian Modeling of Tuberculosis: Forecast for the United States

Sara Debanne
2000 Emerging Infectious Diseases  
Her interests include public health surveillance of STEC and hemolytic uremic syndrome and the investigation of outbreaks of foodborne gastrointestinal disease.  ...  The patient approved the use of his medical record for this work and provided written informed consent. About the Author Dr.  ...  ) at Public Health England for confirmation of identification and typing.  ... 
doi:10.3201/eid0602.000207 pmid:10756148 pmcid:PMC2640843 fatcat:772hgyrffffprdrgyiwb7urehe

Surface water isolates of hemolytic and non-hemolytic Acinetobacter with multiple drug and heavy metal resistance ability

Sevilay Akbulut, Fadime Yilmaz, Bulent Icgen
2013 Journal of Water and Health  
The antibiotic and heavy metal resistance profiles of the isolates were determined by using 26 antibiotics and 17 heavy metals.  ...  Acinetobacter in surface waters are a major concern because of their rapid development of resistance to a wide range of antimicrobials and their ability to persist in these waters for a very long time.  ...  members of the outbreak control team for ACKNOWLEDGEMENTS The authors wish to thank the CICYT (AGL 2006-06523/ ALI) for the financial support for this study and Zeu-Inmunotec for the kind supply of  ... 
doi:10.2166/wh.2013.304 pmid:24642427 fatcat:ylp3vbm7xrefvegnrotcbqun54
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