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SkyPy: A package for modelling the Universe
[article]
2021
arXiv
pre-print
SkyPy is an open-source Python package for simulating the astrophysical sky. It comprises a library of physical and empirical models across a range of observables and a command-line script to run end-to-end simulations. The library provides functions that sample realisations of sources and their associated properties from probability distributions. Simulation pipelines are constructed from these models using a YAML-based configuration syntax, while task scheduling and data dependencies are
arXiv:2109.06172v1
fatcat:diz2atrhjbgzhda2lshy4a2hk4
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... ed internally and the modular design allows users to interface with external software. SkyPy is developed and maintained by a diverse community of domain experts with a focus on software sustainability and interoperability. By fostering development, it provides a framework for correlated simulations of a range of cosmological probes including galaxy populations, large scale structure, the cosmic microwave background, supernovae and gravitational waves. Version 0.4 implements functions that model various properties of galaxies including luminosity functions, redshift distributions and optical photometry from spectral energy distribution templates. Future releases will provide additional modules, for example, to simulate populations of dark matter halos and model the galaxy-halo connection, making use of existing software packages from the astrophysics community where appropriate.
Freshwater Megafauna: Flagships for Freshwater Biodiversity under Threat
2017
BioScience
Photographs: Peter Haase, F. David Carmona, and William Darwall. ...
F reshwater ecosystems cover less than one percent of the planet, but they are among the most diverse and dynamic systems globally (Strayer and Dudgeon 2010) . ...
doi:10.1093/biosci/bix099
pmid:29599539
pmcid:PMC5862257
fatcat:fvjzh2xn65bblil3n7ko2s2e3q
A new multivariable benchmark for Last Glacial Maximum climate simulations
2020
Climate of the Past
F. ...
Sean F. Cleator was supported by a UK Natural Environment Research Council (NERC) scholarship as part of the SCENARIO Doctoral Training Partnership. Sandy P. ...
doi:10.5194/cp-16-699-2020
fatcat:b243no5xpvhipdcbodhanwkrra
Propagation of tau and α-synuclein in the brain: therapeutic potential of the glymphatic system
2022
Translational Neurodegeneration
Tunnelling nanotubes, F-actin containing membranous bridges which connect the cytoplasm of remote cells with one another, can also facilitate cell-to-cell exchange (e). ...
Lastly, protein species have also been shown to be exchanged directly between 'donor' and 'recipient' cells via tunnelling nanotubes (Fig. 2e ), which are F-actin-containing membranous bridges that connect ...
doi:10.1186/s40035-022-00293-2
pmid:35314000
pmcid:PMC8935752
fatcat:ioabnxg25fenroeopsja6hkbkm
Genomic characterisation of Almpiwar virus, Harrison Dam virus and Walkabout Creek virus; three novel rhabdoviruses from northern Australia
2014
Virology Reports
Acknowledgments We gratefully acknowledge many years of dedicated and expert work of Harry Standfast and colleagues, who isolated Almpiwar virus, and likewise Dr Toby St George and colleagues, who isolated Harrison ...
Harrison Dam virus (HARDV), Walkabout Creek virus (WACV) and Almpiwar virus (ALMV) were all isolated during various Australian arbovirus monitoring programmes. ...
doi:10.1016/j.virep.2014.09.001
fatcat:cjgrcxhh6jhjvinpzhfwnzlwkq
Impaired brain glymphatic flow in experimental hepatic encephalopathy
2018
Journal of Hepatology
Mark F. Lythgoe: Contributed funding to the study, developed the MRI methods, and supervised research staff. Alexander V. Gourine and Rajiv Jalan: Led and funded the study. ...
Mark F. ...
thalamus, (E) temporalis muscle, acting as negative control with lack of contrast agent in the temporalis muscle representing a sealed system and no CSF leakage due to the cannula implantation, and (F) ...
doi:10.1016/j.jhep.2018.08.021
pmid:30201461
fatcat:miohfwjnizgexowwia2jmlyaxq
Pharmacological MRI with Simultaneous Measurement of Cerebral Perfusion and Blood-Cerebrospinal Fluid Barrier Function using Interleaved Echo-Time Arterial Spin Labelling
2021
NeuroImage
I.F.H. is supported by research fellowship awards from Alzheimer's Research UK (ARUK-RF2019A-003) and Parkinson's UK (F-1902). M. F. ...
Ian F. Harrison: Conceptualization, Writing -review & editing. Mark F. Lythgoe: Conceptualization, Resources, Writing -review & editing. David L. ...
Fig. 2 (e, f) shows the simultaneous response of cortical blood flow and the BCSFB-ASL signal in response to a hypercapnia challenge. ...
doi:10.1016/j.neuroimage.2021.118270
pmid:34144160
fatcat:jm3zvshh5rfzjgns3rx3ecy57y
A new multi-variable benchmark for Last Glacial Maximum climate simulations
2019
Climate of the Past Discussions
2016; Harrison et al., 2016) . ...
) moisture index (MI), (b) mean annual precipitation (MAP), (c) mean annual temperature (MAT), (d) mean temperature of the coldest month (MTCO), (e) mean temperature of the warmest month (MTWA), and (f) ...
doi:10.5194/cp-2019-55
fatcat:wh7p5mwwqjgmlkfe2fwwlfufhi
Pathological histone acetylation in Parkinson's disease: Neuroprotection and inhibition of microglial activation through SIRT 2 inhibition
2018
Neuroscience Letters
Harrison et al.
Table 1 1 Results of Regression Analyses Performed Between TH, HLA-DPα, SIRT2 Expression and Braak Stage and AcH3-Lys9 Expression. ...
doi:10.1016/j.neulet.2017.12.037
pmid:29273397
pmcid:PMC5821898
fatcat:fhrdr3bmdrao5b2wopp57zkxo4
The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease
2018
Journal of Neurochemistry
These data are consistent with prior observations in this model (Vernon et al. 2011; Harrison et al. 2015) . ...
Appropriately, inhibitors of a number of these classes and sub-classes of HDACs have shown to produce a neuroprotective effect in cell and animal models of PD (for reviews see Harrison and Dexter 2013 ...
doi:10.1111/jnc.14599
pmid:30269333
pmcid:PMC6487684
fatcat:gjuvnzo2u5aixes6ytzmy4bkzu
Actomyosin II contractility expels von Willebrand factor from Weibel–Palade bodies during exocytosis
2011
Journal of Cell Biology
Nightingale, 1, 2, 3 Ian J. White, 1,2 Emily L. Doyle, 1,2,3 Mark Turmaine, 3 Kimberly J. Harrison-Lavoie, 1,2,3 Kathleen F. Webb, 1,2 Louise P. Cramer, 1, 3 and Daniel F. Cutler 1,2,3 Figure 1 . ...
Mean fluorescence The C terminal-tagged P-selectinLum-mCherry fusion construct was generated by amplification from a P-selectin luminal PRK5 construct (Harrison-Lavoie et al., 2006) using primers encoding ...
doi:10.1083/jcb.201011119
pmid:21844207
pmcid:PMC3160584
fatcat:zwvrnjohdnet3pbl74y5msnmuu
Impaired glymphatic function and clearance of tau in an Alzheimer's disease model
2020
Brain
F. Harrison et al.Downloaded from https://academic.oup.com/brain/article-abstract/doi/10.1093/brain/awaa179/5875735 by guest on 28 July 2020
| BRAIN : Page 4 of 18 I. F. ...
Harrison et al.Downloaded from https://academic.oup.com/brain/article-abstract/doi/10.1093/brain/awaa179/5875735 by guest on 28 July 2020
| BRAIN : Page 6 of 18 I. F. ...
doi:10.1093/brain/awaa179
pmid:32705145
fatcat:va7pgbjgybf6lm2carjlss7xjq
Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE ASL MRI
2020
Magnetic Resonance in Medicine
The intravascular fraction F I G U R E 2 Cortical blood-brain barrier permeability to water. ...
F I G U R E 1 Processing pipeline to measure the exchange time (T w ) as an index of blood-brain barrier permeability to water using control data to determine extravascular tissue T 2 (T2 EV ), multiple-echo-time ...
doi:10.1002/mrm.28496
pmid:32910547
pmcid:PMC8432141
fatcat:5f52klxfqncifbhoolcklqs7wi
Imaging of X-Ray-Excited Emissions from Quantum Dots and Biological Tissue in Whole Mouse
2019
Scientific Reports
It was fitted with an unfiltered 35 mm focal length, f/1.4 lens (Nikon Nikkor) for Fig. 1 , and a 28 mm focal-length, f/1.4 NIR lens (Edmund Optics) with a narrow bandpass filter (λ c = 700 nm, FWHM = ...
doi:10.1038/s41598-019-55769-5
pmid:31844147
pmcid:PMC6915766
fatcat:czmm6pej2zg65i7l27t45z5anq
Impaired brain glymphatic flow in a rodent model of chronic liver disease and minimal hepatic encephalopathy
[article]
2017
bioRxiv
pre-print
Mark F. Lythgoe: Contributed funding to the study, developed the MRI methods, and supervised research staff. Alexander V. Gourine and Rajiv Jalan: Led and funded the study. ...
doi:10.1101/173526
fatcat:m5beaymcrzeldkpwjktj5ugxg4
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