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Physiological mechanisms of lung volume reduction coils in emphysema

William McNulty, Pallav Shah, Omar Usmani
2017
Methods A randomised controlled study consisting of thirty patients with severe chronic obstructive pulmonary disease was performed. Control patients crossed over to the treatment arm at 12 months.  ...  Including the crossovers there were 4 patient deaths (13.3%). Target lobe volume at both inspiration and expiration was reduced with no overall change in gas trapping.  ...  Recent re-examination of the ISOLDE data with stratification of patients by peripheral blood eosinophils has identified a group of patients who may benefit more from ICS.  ... 
doi:10.25560/50161 fatcat:cvtvqqrwwbf5bp4vy7wkigi72i