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IRProfiler – a software toolbox for high throughput immune receptor profiling
2018
BMC Bioinformatics
Results: This work introduces Immune Repertoire Profiler (IRProfiler), a novel software pipeline that delivers a number of core receptor repertoire quantification and comparison functionalities on high-throughput ...
In the era of high-throughput sequencing (HTS), the abundance of immunogenetic data has revealed unprecedented opportunities for the thorough profiling of T-cell receptors (TR) and B-cell receptors (BcR ...
The present study introduces a novel software pipeline for immune repertoire profiling of high-throughput TR and BcR sequencing data, called Immunogenetic Repertoire Profiler or IRProfiler. ...
doi:10.1186/s12859-018-2144-z
pmid:29669518
pmcid:PMC5907363
fatcat:giqdpgrf7zbopmotimnvzp6rfe
TRIP - T cell receptor/immunoglobulin profiler
2020
BMC Bioinformatics
The T cell Receptor/Immunoglobulin Profiler (TRIP) tool offers the opportunity for an in-depth analysis based on the processing of the output files of the IMGT/HighV-Quest tool, a standard in NGS immunoprofiling ...
Conclusions TRIP is a software framework that provides analytical services on antigen receptor gene sequence data. ...
Another software toolbox for high throughput immune receptor profiling is available on the Galaxy platform [14] , namely the Immune Receptor Profiler (IRProfiler). ...
doi:10.1186/s12859-020-03669-1
pmid:32993478
pmcid:PMC7525938
fatcat:66twsnm2njh4jpgx5d52at7jzm
The Pipeline Repertoire for Ig-Seq Analysis
2019
Frontiers in Immunology
of antibody repertoires so that the reader better decides a strategic approach for the experimental design, and computational pathways for the analyses of immune repertoires. ...
With the advent of high-throughput sequencing of immunoglobulin genes (Ig-Seq), the understanding of antibody repertoires and their dynamics among individuals and populations has become an exciting area ...
Maramis C, Gkoufas A, Vardi A, Stalika E, Stamatopoulos K, Hatzidimitriou A, et al. IRProfiler - a software toolbox for high throughput immune receptor profiling. ...
doi:10.3389/fimmu.2019.00899
pmid:31114573
pmcid:PMC6503734
fatcat:gkzwlvt235hlrhvwlfcdsspwwi
Ανοσογενετική ανάλυση του ρεπερτορίου του Τ κυτταρικού υποδοχέα των κυτταροτοξικών Τ λεμφοκυττάρων με αλληλούχηση υψηλής απόδοσης
2018
In the era of high throughput sequencing, our perceptions about immune responses will be revised. ...
In order to overcome these limitations and obtain insight into the role of antigenic drive in T-LGL lymphoproliferations, we here exploited high-throughput next generation sequencing (NGS) to interrogate ...
IRProfiler – A Software Toolbox for High Throughput
Immune Receptor Profiling. 2018;1–11.
93. Thomas N, Heather J, Ndifon W, Shawe-Taylor J, Chain B. ...
doi:10.26262/heal.auth.ir.298746
fatcat:34uykofx6jgutcrkl36sgzwspm