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Editorial: Precision Public Health

Tarun Stephen Weeramanthri, Hugh J. S. Dawkins, Gareth Baynam, Matthew Bellgard, Ori Gudes, James Bernard Semmens
2018 Frontiers in Public Health  
doi:10.3389/fpubh.2018.00121 pmid:29761096 pmcid:PMC5937027 fatcat:mlmwl5tpznbpbfujeko5qoayee

The Evolution of Public Health Genomics: Exploring Its Past, Present, and Future

Caron M. Molster, Faye L. Bowman, Gemma A. Bilkey, Angela S. Cho, Belinda L. Burns, Kristen J. Nowak, Hugh J. S. Dawkins
2018 Frontiers in Public Health  
Consequently, attention has shifted toward rare and monogenic diseases where the gene and phenotype(s) may result in more clear causal pathologies.  ...  s. (31) work to provide examples from the literature of how genomics BOX 5 | Case Study-Ethical, legal, and social implications to consider for applications of public health genomics.  ... 
doi:10.3389/fpubh.2018.00247 pmid:30234091 pmcid:PMC6131666 fatcat:3uhpynkxy5anhfml5tnf6mgtky

Human gene patents: the possible impacts on genetic services healthcare

Ian R Walpole, Hugh J S Dawkins, Peter D Sinden, Peter C O'Leary
2003 Medical Journal of Australia  
J S Dawkins, Peter D Sinden and Peter C O'Leary ABSTRACT ■ The patent system has been seen as a critical factor driving innovation in clinical medicine, particularly in medical devices and diagnostic  ...  patent rights in this way is directly contrary to the fundamental policy objectives underlying the patent system. 7 Human gene patents: the possible impacts on genetic services healthcare Ian R Walpole, Hugh  ... 
pmid:12914511 fatcat:jonpw6z5zfedlhp5zv73eb67sa

Field inversion gel electrophoresis (FIGE) in vertical slabs as an improved method for large DNA separation

Hugh J. S. Dawkins, Debra J. Ferrier, Terence L. Spencer
1987 Nucleic Acids Research  
Field inversion gel electrophoresis (FIGE) has made separation of very large DNA and intact chromosomes a simple operation by utilising conventional submarine agarose gel electrophoresis equipment in conjunction with a switching unit to control the electric fieldl2.
doi:10.1093/nar/15.8.3634 pmid:3575112 pmcid:PMC340767 fatcat:zbda46mfgbfrhprtt2a3z6tvhq

Healthcare System Priorities for Successful Integration of Genomics: An Australian Focus

Belinda L. Burns, Gemma A. Bilkey, Emily P. Coles, Faye L. Bowman, John P. Beilby, Nicholas S. Pachter, Gareth Baynam, Hugh J. S. Dawkins, Tarun S. Weeramanthri, Kristen J. Nowak
2019 Frontiers in Public Health  
However, the type of model for gatekeeping genomic testing, genetic counselling and seeking consent will depend on the characteristics of the condition/s being tested for and the test.  ...  higher than usual risk of having an offspring with a genetic condition who may wish to access such a technology to proactively prevent their future child having or developing that specific genetic disease/s.  ...  Copyright © 2019 Burns, Bilkey, Coles, Bowman, Beilby, Pachter, Baynam, Dawkins, Weeramanthri and Nowak.  ... 
doi:10.3389/fpubh.2019.00041 pmid:30915324 pmcid:PMC6421399 fatcat:buyejy2gjrextjtn6afiainxcy

Review of Current International Decision-Making Processes for Newborn Screening: Lessons for Australia

Selina Carolyne Metternick-Jones, Karla Jane Lister, Hugh J. S. Dawkins, Craig Anthony White, Tarun Stephen Weeramanthri
2015 Frontiers in Public Health  
doi:10.3389/fpubh.2015.00214 pmid:26442241 pmcid:PMC4564656 fatcat:l2qi4unvgvcz7a6a5mfekv54vu

3-Dimensional Facial Analysis—Facing Precision Public Health

Gareth Baynam, Alicia Bauskis, Nicholas Pachter, Lyn Schofield, Hedwig Verhoef, Richard L. Palmer, Stefanie Kung, Petra Helmholz, Michael Ridout, Caroline E. Walker, Anne Hawkins, Jack Goldblatt (+3 others)
2017 Frontiers in Public Health  
Precision public health is a new field driven by technological advances that enable more precise descriptions and analyses of individuals and population groups, with a view to improving the overall health of populations. This promises to lead to more precise clinical and public health practices, across the continuum of prevention, screening, diagnosis, and treatment. A phenotype is the set of observable characteristics of an individual resulting from the interaction of a genotype with the
more » ... nment. Precision (deep) phenotyping applies innovative technologies to exhaustively and more precisely examine the discrete components of a phenotype and goes beyond the information usually included in medical charts. This form of phenotyping is a critical component of more precise diagnostic capability and 3-dimensional facial analysis (3DFA) is a key technological enabler in this domain. In this paper, we examine the potential of 3DFA as a public health tool, by viewing it against the 10 essential public health services of the "public health wheel," developed by the US Centers for Disease Control. This provides an illustrative framework to gage current and emergent applications of genomic technologies for implementing precision public health.
doi:10.3389/fpubh.2017.00031 pmid:28443272 pmcid:PMC5385440 fatcat:s7wkmcoginadbob6bvuztlaggi

Genomic Testing for Human Health and Disease Across the Life Cycle: Applications and Ethical, Legal, and Social Challenges

Gemma A. Bilkey, Belinda L. Burns, Emily P. Coles, Faye L. Bowman, John P. Beilby, Nicholas S. Pachter, Gareth Baynam, Hugh J. S. Dawkins, Kristen J. Nowak, Tarun S. Weeramanthri
2019 Frontiers in Public Health  
This follows identification of increased risk of the embryo having a genetic condition via molecular diagnosis or carrier screening of the parent/s.  ...  Prognostic Utilizes gene variant/s or expression information to predict disease progression, severity and outcomes, as well as optimize and monitor therapeutic interventions.  ...  Copyright © 2019 Bilkey, Burns, Coles, Bowman, Beilby, Pachter, Baynam, Dawkins, Nowak and Weeramanthri.  ... 
doi:10.3389/fpubh.2019.00040 pmid:30915323 pmcid:PMC6421958 fatcat:mpqzeav435egxoqr6fsfnkikwu

International Charter of principles for sharing bio-specimens and data

Deborah Mascalzoni, Edward S Dove, Yaffa Rubinstein, Hugh J S Dawkins, Anna Kole, Pauline McCormack, Simon Woods, Olaf Riess, Franz Schaefer, Hanns Lochmüller, Bartha M Knoppers, Mats Hansson
2014 European Journal of Human Genetics  
doi:10.1038/ejhg.2014.197 pmid:25248399 pmcid:PMC4795058 fatcat:kl3xk4zbgremtg2d5wykncxc6e

Outcomes of an International Workshop on Preconception Expanded Carrier Screening: Some Considerations for Governments

Caron M. Molster, Karla Lister, Selina Metternick-Jones, Gareth Baynam, Angus John Clarke, Volker Straub, Hugh J. S. Dawkins, Nigel Laing
2017 Frontiers in Public Health  
GB, SM-J, AC, VS, HD, and NL critically revised the manuscript for important intellectual content.  ...  Participants recommended that, as part of a program, information should be provided that would make the aim(s) of the program clear and encapsulate the benefits, risks, harms, consequences, uncertainties  ... 
doi:10.3389/fpubh.2017.00025 pmid:28286745 pmcid:PMC5323409 fatcat:j3cewopymvgcnoyvlk2cenkgdq

The collective impact of rare diseases in Western Australia: an estimate using a population-based cohort

Caroline E. Walker, Trinity Mahede, Geoff Davis, Laura J. Miller, Jennifer Girschik, Kate Brameld, Wenxing Sun, Ana Rath, Ségolène Aymé, Stephen R. Zubrick, Gareth S. Baynam, Caron Molster (+2 others)
2016 Genetics in Medicine  
In some cases, because of discrepancies between the ICD-10 and ICD-10-AM coding systems, the ICD-10-AM code(s) that specifically corresponded to an Orpha code was different from the ICD-10 code provided  ...  disease 89 88 1.5 1 Rare circulatory system disease 8 7 1.3 1 Rare abdominal surgical disease a a a a Impact of rare diseases in Western Australia | WALKER et al © The Author(s)  ... 
doi:10.1038/gim.2016.143 pmid:27657686 pmcid:PMC5440569 fatcat:ypmesokgwrfwvijh2hewzbskyq

A flexible computational pipeline for research analyses of unsolved clinical exome cases

Timo Lassmann, Richard W. Francis, Alexia Weeks, Dave Tang, Sarra E. Jamieson, Stephanie Broley, Hugh J. S. Dawkins, Lauren Dreyer, Jack Goldblatt, Tudor Groza, Benjamin Kamien, Cathy Kiraly-Borri (+12 others)
2020 npj Genomic Medicine  
in partnership with CEGMR, King Abdulaziz University npj Genomic Medicine (2020) 54 npj Genomic Medicine (2020) 54Published in partnership with CEGMR, King Abdulaziz University © The Author(s)  ...  Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s)  ... 
doi:10.1038/s41525-020-00161-w pmid:33303739 fatcat:bowhun4ghzalhhu7qhisrlx6uy

Equitable Expanded Carrier Screening Needs Indigenous Clinical and Population Genomic Data

Simon Easteal, Ruth M. Arkell, Renzo F. Balboa, Shayne A. Bellingham, Alex D. Brown, Tom Calma, Matthew C. Cook, Megan Davis, Hugh J.S. Dawkins, Marcel E. Dinger, Michael S. Dobbie, Ashley Farlow (+29 others)
2020 American Journal of Human Genetics  
, Hugh, J.S  ...  Jiang, Simon, H. 6 21 ; Meldrum, Cliff, J. 22 ; Nagaraj, Shivashankar, H. 23 ; Newman, Saul, J. 24 ; Nunn, Jack, S. 25 ; Ormond-Parker, Lyndon 26 ; Orr, Neil, J. 5 ; Paliwal, Devashi  ... 
doi:10.1016/j.ajhg.2020.06.005 pmid:32763188 pmcid:PMC7413856 fatcat:zjn6n25oeve6tlqmpq6cle3l4q

Enabling Global Clinical Collaborations on Identifiable Patient Data: The Minerva Initiative

Christoffer Nellåker, Fowzan S. Alkuraya, Gareth Baynam, Raphael A. Bernier, Francois P.J. Bernier, Vanessa Boulanger, Michael Brudno, Han G. Brunner, Jill Clayton-Smith, Benjamin Cogné, Hugh J.S. Dawkins, Bert B.A. deVries (+41 others)
2019 Frontiers in Genetics  
EEE is supported by NIH 5R01MH101221 and as an investigator of Howard Hughes Medical Institute. CR acknowledges funding by the Italian Ministry of Health, Project RC2019 No. 2751604.  ...  The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in  ...  Copyright © 2019 Nellåker, Alkuraya, Baynam, Bernier, Bernier, Boulanger, Brudno, Brunner, Clayton-Smith, Cogné, Dawkins, deVries, Douzgou, Dudding-Byth, Eichler, Ferlaino, Fieggen, Firth, FitzPatrick  ... 
doi:10.3389/fgene.2019.00611 pmid:31417602 pmcid:PMC6681681 fatcat:w6pc7y23vjg2lbhmlbpd7ntrkm

Page 298 of The New England Historical and Genealogical Register Vol. 40, Issue [page]

1886 The New England Historical and Genealogical Register  
Dawkins, Maverick. Maverick. Child. Hurd. Dawkins. Callender. Hurd. H. Morse. Callender. Revere. Hurd. Maverick. s. Hurd. Mass. it Mass.  ...  Cooper, Myles Courtenay, Henry Curwen Cutting, James S. Dana, ‘rancis “ — Richard H.  ... 
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