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Connectivity Gradients Between the Default Mode and Attention Control Networks

Jeffrey S. Anderson, Michael A. Ferguson, Melissa Lopez-Larson, Deborah Yurgelun-Todd
2011 Brain Connectivity  
Such gradients were reproduced in 3 separate groups of subjects. Anticorrelated subregions were identified in major hubs of both networks.  ...  We analyzed resting state blood oxygen level dependent (BOLD) data from 1278 subjects from 26 sites and constructed whole-brain maps of functional connectivity between 7266 regions of interest (ROIs) covering  ...  Investigators and funding sources who contributed to the 1000 Functional Connectome Dataset and ADHD 200 Dataset are available at http://fcon_1000.projects.nitrc.org/ Author Disclosure Statement No competing  ... 
doi:10.1089/brain.2011.0007 pmid:22076305 pmcid:PMC3209669 fatcat:xpdsc73jtzgsbddx2qbjkpfm3q

Association between Functional Connectivity Hubs and Brain Networks

Dardo Tomasi, Nora D. Volkow
2011 Cerebral Cortex  
Whereas cortical local FCD hubs were also hubs of long-range connectivity, which corroborates the key role of cortical hubs in network architecture, subcortical hubs had minimal long-range connectivity  ...  Here, we used the functional hubs obtained from local FCDM to determine the functional networks of the resting state in 979 healthy subjects without a priori hypotheses on seed locations.  ...  Similarly, the resting-state activity in the PC-VP hub was significantly anticorrelated with the average activity in the postcentral hub network.  ... 
doi:10.1093/cercor/bhq268 pmid:21282318 pmcid:PMC3165965 fatcat:g3aidsxtfrbn3pgvtppfzrd2um

Network structure of cerebral cortex shapes functional connectivity on multiple time scales

C. J. Honey, R. Kotter, M. Breakspear, O. Sporns
2007 Proceedings of the National Academy of Sciences of the United States of America  
As a result, hubs in these long-run functional networks correspond to structural hubs.  ...  These slow variations, both in functional connectivity and in values of estimated regional blood oxygenation level-dependent (BOLD) signal, were coordinated via anatomical connection patterns, and we defined  ...  organization and the existence of hubs in functional connectivity networks (17) (18) (19) (20) and (ii) functional clusters that are anticorrelated on a time scale of seconds (8, 10) and possibly  ... 
doi:10.1073/pnas.0701519104 pmid:17548818 pmcid:PMC1891224 fatcat:3azr2a6nabfr7arpimy6hbdday

The Hierarchical Organization of the Default, Dorsal Attention and Salience Networks in Adolescents and Young Adults

Yuan Zhou, Karl J Friston, Peter Zeidman, Jie Chen, Shu Li, Adeel Razi
2017 Cerebral Cortex  
This anticorrelation may constitute a key aspect of functional anatomy and is implicated in several brain disorders.  ...  These new findings shed light on functional integration of intrinsic brain networks at rest and speak to future dynamic causal modeling studies of large-scale networks.  ...  Functional Architecture of Resting State Networks A fundament of brain organization is the integration of functionally segregated brain regions (Park and Friston 2013) .  ... 
doi:10.1093/cercor/bhx307 pmid:29161362 pmcid:PMC5929108 fatcat:xiym3orb4rh7bmfegvnd7esioq

Development of the Default Mode and Central Executive Networks across early adolescence: A longitudinal study

Lauren E. Sherman, Jeffrey D. Rudie, Jennifer H. Pfeifer, Carrie L. Masten, Kristin McNealy, Mirella Dapretto
2014 Developmental Cognitive Neuroscience  
These findings highlight early adolescence as a period of significant maturation for the brain's functional architecture and demonstrate the utility of longitudinal designs to investigate neural network  ...  Using functional magnetic resonance imaging (fMRI), we examined the Default Mode Network (DMN) and the Central Executive Network (CEN) at ages 10 and 13 in a longitudinal sample of 45 participants.  ...  This project was also partially supported by grants (RR12169, RR13642 and RR00865) from the National Center for Research Resources, a component of the National Institutes of Health.  ... 
doi:10.1016/j.dcn.2014.08.002 pmid:25282602 pmcid:PMC4854607 fatcat:5vxoxin3kfevpicqqw4bq5ki2m

Large-scale brain systems in ADHD: beyond the prefrontal–striatal model

F. Xavier Castellanos, Erika Proal
2012 Trends in Cognitive Sciences  
Recent advances in systems neuroscience-based approaches to brain dysfunction have facilitated the development of models of ADHD pathophysiology that encompass a number of different large-scale resting-state  ...  Insights emerging from mapping intrinsic brain connectivity networks provide a potentially mechanistic framework for an understanding of aspects of ADHD such as neuropsychological and behavioral inconsistency  ...  Resting-state functional magnetic resonance imaging Resting-state functional imaging, that is, imaging without a specific task (Box 1), is not new.  ... 
doi:10.1016/j.tics.2011.11.007 pmid:22169776 pmcid:PMC3272832 fatcat:nk7yhobxlvaefh7ki25sumgfha

Dynamical consequences of lesions in cortical networks

Christopher J. Honey, Olaf Sporns
2008 Human Brain Mapping  
To understand the effects of a cortical lesion it is necessary to consider not only the loss of local neural function, but also the lesion-induced changes in the larger network of endogenous oscillatory  ...  their coupling architecture from the available anatomical connection data for macaque cerebral cortex.  ...  This model and metric have previously been successful in relating the clustered architecture of the macaque anatomical network to resting state functional connectivity in the same animal [Honey et al.  ... 
doi:10.1002/hbm.20579 pmid:18438885 fatcat:wqn7x5ya3ffl7kdzry6zudp4pq

Intrinsic Functional Connectivity As a Tool For Human Connectomics: Theory, Properties, and Optimization

Koene R. A. Van Dijk, Trey Hedden, Archana Venkataraman, Karleyton C. Evans, Sara W. Lazar, Randy L. Buckner
2010 Journal of Neurophysiology  
Neuroimage 31: 1536 -1548, 2006. 317 INTRINSIC FUNCTIONAL CONNECTIVITY The effect of respiration variations on independent component analysis results of resting state functional connectivity.  ...  Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 34: 537-541, 1995.  ...  However, because spontaneous fluctuations are often measured at rest, the method is frequently referred to as "resting state" fcMRI (R-fcMRI) and the identified brain networks as "resting state networks  ... 
doi:10.1152/jn.00783.2009 pmid:19889849 pmcid:PMC2807224 fatcat:ygqtjzyesfbkfjft7i72g263we

Controllability of structural brain networks

Shi Gu, Fabio Pasqualetti, Matthew Cieslak, Qawi K. Telesford, Alfred B. Yu, Ari E. Kahn, John D. Medaglia, Jean M. Vettel, Michael B. Miller, Scott T. Grafton, Danielle S. Bassett
2015 Nature Communications  
Weakly connected areas, particularly in cognitive control systems, facilitate the movement of the brain to difficult-to-reach states.  ...  Our results suggest that densely connected areas, particularly in the default mode system, facilitate the movement of the brain to many easily-reachable states.  ...  Modular structure has been reported in structural, functional and dynamic brain networks 41 . In resting state connectivity studies, these modules have been linked to known cognitive systems 11 .  ... 
doi:10.1038/ncomms9414 pmid:26423222 pmcid:PMC4600713 fatcat:7gad7f7aifb2xcz4ruwmlolpju

Driving and Driven Architectures of Directed Small-World Human Brain Functional Networks

Chaogan Yan, Yong He, Michal Zochowski
2011 PLoS ONE  
) to explore connectivity patterns of the population-based whole-brain functional directed network.  ...  Here, we applied linear multivariate Granger causality analysis (GCA) and graph theoretical approaches to a resting-state functional MRI dataset with a large cohort of young healthy participants (n = 86  ...  Here, we used resting-state functional MRI (R-fMRI) data to investigate the driving and driven architecture of human brain directed network.  ... 
doi:10.1371/journal.pone.0023460 pmid:21858129 pmcid:PMC3155571 fatcat:zckgwz6vyjhszchthomvoqlbfm

Comparing connectivity pattern and small-world organization between structural correlation and resting-state networks in healthy adults

S.M. Hadi Hosseini, Shelli R. Kesler
2013 NeuroImage  
Resting-state networks (RSN), derived from coordinated variations in neural activity at rest, have been shown to reflect connectivity between functionally related regions as well as, to some extent, anatomical  ...  Conversely, the small-world parameters of the networks were significantly different, suggesting that SCN topological parameters cannot be regarded as a substitute for topological organization in resting-state  ...  Acknowledgments This work was supported by grants from the National Institutes of Health (1 DP2 OD004445-01 to SK).  ... 
doi:10.1016/j.neuroimage.2013.04.032 pmid:23603348 pmcid:PMC3673883 fatcat:wucktwrx2za3hbggywdl2a5dvi

Network structure of the mouse brain connectome with voxel resolution [article]

Ludovico Coletta, Marco Pagani, Jennifer D Whitesell, Julie A Harris, Boris Bernhardt, Alessandro Gozzi
2020 bioRxiv   pre-print
Together, our results reveal a high-resolution structural scaffold linking mesoscale connectome topography to its macroscale functional organization, and create opportunities for identifying targets of  ...  These structural features can be related to patterns of intralaminar connectivity and to the spatial topography of dynamic fMRI brain states, respectively.  ...  high resolution matrix.  ... 
doi:10.1101/2020.03.06.973164 fatcat:sovhwoobavey3fd6ejewgbro7m

High-Resolution Functional Connectivity Density: Hub Locations, Sensitivity, Specificity, Reproducibility, and Reliability

Dardo Tomasi, Ehsan Shokri-Kojori, Nora D. Volkow
2015 Cerebral Cortex  
Prior neuroimaging studies have identified at the group-level local functional connectivity density (lFCD) hubs, network nodes with high degree of connectivity with neighboring regions, in occipito-parietal  ...  However, the individual patterns and the precision for the location of the hubs were limited by the restricted spatiotemporal resolution of the magnetic resonance imaging (MRI) measures collected at rest  ...  Smoothing was not used to preserve the high spatial resolution of the resting-state functional dataset.  ... 
doi:10.1093/cercor/bhv171 pmid:26223259 pmcid:PMC4898675 fatcat:d67ypudsmzdxhjijahtsmunwlu

Brain Connectivity Analysis: A Short Survey

E. W. Lang, A. M. Tomé, I. R. Keck, J. M. Górriz-Sáez, C. G. Puntonet
2012 Computational Intelligence and Neuroscience  
Resting state conditions have become a dominant experimental paradigm, and a number of resting state networks, among them the prominent default mode network, have been identified.  ...  The last decade has seen an ever increasing number of studies devoted to deduce functional or effective connectivity, mostly from functional neuroimaging experiments.  ...  Although attenuated during task performance, the DMN is active in the resting state with a high degree of functional connectivity between brain areas.  ... 
doi:10.1155/2012/412512 pmid:23097663 pmcid:PMC3477528 fatcat:zlwqwx6n7feefdrfx5pnhhbmhe

Abnormal brain synchrony in Down Syndrome

Jeffrey S. Anderson, Jared A. Nielsen, Michael A. Ferguson, Melissa C. Burback, Elizabeth T. Cox, Li Dai, Guido Gerig, Jamie O. Edgin, Julie R. Korenberg
2013 NeuroImage: Clinical  
A functional parcellation of the brain showed simplified network structure in Down Syndrome organized by local connectivity.  ...  Short-range, increased synchrony was not observed in a comparison sample of 447 autism vs. 517 control subjects from the Autism Brain Imaging Exchange (ABIDE) collection of resting state fMRI data, and  ...  The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Mental Health or the National Institutes of Health.  ... 
doi:10.1016/j.nicl.2013.05.006 pmid:24179822 pmcid:PMC3778249 fatcat:szuija3ggvdsrobdlg5rg4j7we
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