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High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID)

Barry R Zeeberg, Haiying Qin, Sudarshan Narasimhan, Margot Sunshine, Hong Cao, David W Kane, Mark Reimers, Robert M Stephens, David Bryant, Stanley K Burt, Eldad Elnekave, Danielle M Hari (+5 others)
2005 BMC Bioinformatics  
For illustration, we show an application of this new tool to the interpretation of altered gene expression patterns in Common Variable Immune Deficiency (CVID).  ...  We previously developed GoMiner, an application that organizes lists of 'interesting' genes (for example, under-and overexpressed genes from a microarray experiment) for biological interpretation in the  ...  For illustration, we show an application of this new tool to the interpretation of altered gene expression patterns in Common Variable Immune Deficiency (CVID).  ... 
doi:10.1186/1471-2105-6-168 pmid:15998470 pmcid:PMC1190154 fatcat:ijds5wnrkvfmba4477d7sby2lq

Time course investigation of PPARα- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression

Blair U. Bradford, Joseph G. Ibrahim, Oksana Kosyk, Michael L. Cunningham, Amanda M. Burns, Ivan Rusyn, Courtney G. Woods, Pamela K. Ross, Pingping Qu
2007
In an effort to determine the timing of the transition from Kupffer cell- to PPARα-dependent modulation of peroxisome proliferator effects, gene expression was assessed in liver from Pparα-null, p47phox-null  ...  Recent studies have demonstrated, by using p47phox-null mice which are deficient in NADPH oxidase, that this enzyme is not related to the phenotypic events caused by prolonged administration of peroxisome  ...  High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency  ... 
doi:10.17615/g4tr-1q92 fatcat:qgdzccn6afexrjjukmel7hd3tm

Referee report. For: Interactive Clustered Heat Map Builder: An easy web-based tool for creating sophisticated clustered heat maps [version 1; peer review: 1 approved]

Natasha Caplen, Soumya Sundara Rajan
2019
.: High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency  ...  Our web-based Interactive Heat Map Builder can be used by investigators with no bioinformatics experience to generate high-caliber, publication quality maps.  ...  Our Iterative CHM Builder is a web-based tool for generation of high-quality heat maps that can be used by investigators with no bioinformatics experience and only modest exposure to biostatistical methods  ... 
doi:10.5256/f1000research.22637.r55133 fatcat:kbhvhgeqaff6tbdqapgflqpkua