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Achieving High-Resolution 1H-MRSI of the Human Brain with Compressed-Sensing and Low-Rank Reconstruction at 7 Tesla

Antoine Klauser, Bernhard Strasser, Bijaya Thapa, Francois Lazeyras, Ovidiu Andronesi
2021 Journal of magnetic resonance (San Diego, Calif. 1997 : Print)  
This new application of compressed sensing acceleration paves the way for high-resolution MRSI in clinical setting with acquisition times of 5 min for 2D MRSI at 2.5 mm and of 20 min for 3D MRSI at 3.3  ...  The MRSI method was validated in a high-resolution phantom containing fine metabolite structures, and in five healthy volunteers.  ...  Acknowledgments This research was supported by the Swiss National Science Foundation Grant No.: IZSEZ0_188859, and the National Institutes of Health through National Cancer Institute grant 1R01CA211080  ... 
doi:10.1016/j.jmr.2021.107048 pmid:34438355 pmcid:PMC8717865 fatcat:pfidjvdn4rcklaqnsgcgz2gfea

Achieving High-Resolution Whole-Brain Slab 1H-MRSI with Compressed-Sensing and Low-Rank Reconstruction at 7 Tesla [article]

Antoine Klauser, Bernhard Strasser, Bijaya Thapa, Francois Lazeyras, Ovidiu Andronesi
2020 bioRxiv   pre-print
This new application of compressed sensing acceleration paves the way for high-resolution MRSI in clinical setting with acquisition times of 5 min for 2D MRSI at 2.5~mm and of 20 min for 3D MRSI at 3.3  ...  The MRSI method was validated in a high-resolution phantom containing fine metabolite structures, and in 3 healthy volunteers.  ...  This research was supported by the Swiss National Science Foundation grant number: IZSEZ0 188859, and the National Institutes of Health through National Cancer Institute grant 1R01CA211080.  ... 
doi:10.1101/2020.05.13.092668 fatcat:wi755wcl7zglzau2sxky2ec5nq

Test-retest reproducibility of human brain multi-slice 1H FID-MRSI data at 9.4 T after optimization of lipid regularization, macromolecular model and spline baseline stiffness [article]

Theresia Ziegs, Andrew Martin Wright, Anke Henning
2022 bioRxiv   pre-print
data spanning the whole cerebrum of human brain and its reproducibility of metabolite ratio (/tCr) maps for 10 brain metabolites.  ...  Methods: Measurements were performed twice on five volunteers using a non-accelerated FID MRSI 2D sequence at 9.4 T.  ...  FID-MRSI data spanning the whole cerebrum of human brain and its reproducibility of metabolite ratio (/tCr) maps for 10 brain metabolites.  Methods: Measurements were performed twice on five volunteers  ... 
doi:10.1101/2022.02.02.478678 fatcat:yad6l6s2d5a4da6j6mag3gi4u4

Quantitative Magnetic Resonance Spectroscopy of Brain Metabolites and Macromolecules at Ultra-High Field [article]

Saipavitra Venkateshwaran Murali Manohar, Universitaet Tuebingen, Henning, Anke (Prof. Dr.)
2021
The first part of the thesis focuses on characterizing the physical properties of macromolecular resonances in the human brain at 9.4 T and understanding their contribu [...]  ...  Ultra-high field (≥7 T) MRS benefits from increased signal-to-noise ratio (SNR) and improved spectral resolution.  ...  High and ultra-high resolution metabolite mapping of the human brain using 1H FID MRSI at 9.4T. Neuroimage. 2018;168:211-221. doi:10.1016/j.neuroimage.2016.12.065 90.  ... 
doi:10.15496/publikation-60424 fatcat:egvotwkfbvc7xifxhdsxvrxhne

Magnetic Resonance Spectroscopy: Quantitative Analysis of Brain Metabolites and Macromolecules [article]

Tamás Borbáth, Universitaet Tuebingen, Henning, Anke (Prof. Dr.)
2021
The upfield spectrum contains most brain metabolites of clinical interest.  ...  Proton magnetic resonance spectroscopy (1H-MRS) allows non-invasive quantification of the human brain's metabolism in vivo. 1H-MRS measures the interaction of the 1H-hydrogen isotope with oscillating electromagnetic  ...  This finding is in agreement with the results of high-resolution MRSI studies 77, 78 .  ... 
doi:10.15496/publikation-58677 fatcat:3j7juyzf3ja7blribpccwnor4m