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Correction: Heterogeneity, Mixing, and the Spatial Scales of Mosquito-Borne Pathogen Transmission

2014 PLoS Computational Biology  
doi:10.1371/journal.pcbi.1003540 fatcat:hniqrel6gng2tez3m3223ygffe

Heterogeneity, Mixing, and the Spatial Scales of Mosquito-Borne Pathogen Transmission

T. Alex Perkins, Thomas W. Scott, Arnaud Le Menach, David L. Smith, Marcel Salathé
2013 PLoS Computational Biology  
Using these tools, we propose two ways of characterizing the spatial scales of transmission-pathogen dispersion kernels and the evenness of mixing across scales of aggregation-and demonstrate the consequences  ...  The Ross-Macdonald model has dominated theory for mosquito-borne pathogen transmission dynamics and control for over a century.  ...  Acknowledgments We thank RC Reiner, TJ Hladish, and JRC Pulliam for feedback on the manuscript. Thanks to J Stoller for producing Fig. 1 .  ... 
doi:10.1371/journal.pcbi.1003327 pmid:24348223 pmcid:PMC3861021 fatcat:ox6arsz6hzbz3hbxlwh4bzhlse

A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970-2010

R. C. Reiner, T. A. Perkins, C. M. Barker, T. Niu, L. F. Chaves, A. M. Ellis, D. B. George, A. Le Menach, J. R. C. Pulliam, D. Bisanzio, C. Buckee, C. Chiyaka (+19 others)
2013 Journal of the Royal Society Interface  
We thank three anonymous reviewers for comments that improved the manuscript.  ...  Modern theory would benefit from an expansion around the concepts of heterogeneous mosquito biting, poorly mixed mosquito-host encounters, spatial heterogeneity and temporal variation in the transmission  ...  On the whole, the publication of models of all mosquitoborne pathogens has been increasing over the past 40 years Host Owing to the short time scales usually considered by models of mosquito-borne pathogen  ... 
doi:10.1098/rsif.2012.0921 pmid:23407571 pmcid:PMC3627099 fatcat:jfhvqrbx6fcb3a5fq5imystgpu

Recasting the theory of mosquito-borne pathogen transmission dynamics and control

D. L. Smith, T. A. Perkins, R. C. Reiner, C. M. Barker, T. Niu, L. F. Chaves, A. M. Ellis, D. B. George, A. Le Menach, J. R. C. Pulliam, D. Bisanzio, C. Buckee (+21 others)
2014 Transactions of the Royal Society of Tropical Medicine and Hygiene  
transmission rely on data describing the intensity and scale of transmission. 555 The challenge is that transmission of mosquito-borne pathogens is likely heterogeneous at 556 every scale.  ...  Given the 81 complex, quantitative nature of control targets and policy for mosquito-borne diseases, 82 dynamic models of mosquito-borne pathogen transmission (MBPT) are indispensable tools 83 for investigating  ... 
doi:10.1093/trstmh/tru026 pmid:24591453 pmcid:PMC3952634 fatcat:i6vlsm4plfe4xm5q4gummbm2wm

From puddles to planet: modeling approaches to vector-borne diseases at varying resolution and scale

Philip A Eckhoff, Caitlin A Bever, Jaline Gerardin, Edward A Wenger, David L Smith
2015 Current Opinion in Insect Science  
in biting rate, realistic vector feeding behavior, and spatial heterogeneity.  ...  Since the original Ross-Macdonald formulations of vectorborne disease transmission, there has been a broad proliferation of mathematical models of vector-borne disease, but many of these models retain  ...  Filling in the intermediate spatial scales Between the scales of the very short spatial-scale aquatic habitats modeled in mechanistic detail [10] and the global patterns of mosquito species habitat  ... 
doi:10.1016/j.cois.2015.05.002 pmid:29587999 fatcat:imm2muc3gnhhppvwvzbqtd63oi

A network-patch methodology for adapting agent-based models for directly transmitted disease to mosquito-borne disease

Carrie A. Manore, Kyle S. Hickmann, James M. Hyman, Ivo M. Foppa, Justin K. Davis, Dawn M. Wesson, Christopher N. Mores
2015 Journal of Biological Dynamics  
We investigated the importance of heterogeneity in mosquito population dynamics and host movement on pathogen transmission, motivating the utility of detailed models of individual behavior.  ...  Our hybrid agent-based/differential equation model is able to quantify the importance of the heterogeneity in predicting the spread and invasion of mosquito-borne pathogens.  ...  The hybrid model described here focuses on the transmission dynamics of mosquito-borne pathogens, but extensions are possible to other arthropod vectors and zoonotic or animal vector-borne pathogens.  ... 
doi:10.1080/17513758.2015.1005698 pmid:25648061 pmcid:PMC5473441 fatcat:ijde4wj3tvd4bmhmfvd7ctugva

Pathogenic landscapes: Interactions between land, people, disease vectors, and their animal hosts

Eric F Lambin, Annelise Tran, Sophie O Vanwambeke, Catherine Linard, Valérie Soti
2010 International Journal of Health Geographics  
We formulated ten propositions that are related to landscape attributes, spatial patterns and habitat connectivity, pathways of pathogen transmission between vectors and hosts, scale issues, land use and  ...  Conclusions: A static view of the "pathogenecity" of landscapes overlays maps of the spatial distribution of vectors and their habitats, animal hosts carrying specific pathogens and their habitat, and  ...  We are grateful to partners of the EDEN project who have shared their data and expertise on the case studies.  ... 
doi:10.1186/1476-072x-9-54 pmid:20979609 pmcid:PMC2984574 fatcat:lpxw3bt2gnfyldutrcfscsi7ei

Effects of Spatial Heterogeneity on Transmission Potential in Vectorial-Contact Networks: A Comparison of Three Aedes aegypti Control Strategies [article]

Hector M. Sanchez C., John M. Marshall, Sean L. Wu, Edgar E. Vallejo
2017 bioRxiv   pre-print
Despite the strong influence of host spatial distribution and movement patterns on the ability of mosquito vectors to transmit pathogens, there is little understanding how these complex interactions modify  ...  the spread of disease in spatially heterogeneous populations.  ...  Arriaga, Benjamín Valdés and Victor Ferman for their kind comments and help in the writing of this paper.  ... 
doi:10.1101/210450 fatcat:k3grjdlesvg5zfbxqapqkhbezq

Spatially disaggregated disease transmission risk: land cover, land use and risk of dengue transmission on the island of Oahu

Sophie O. Vanwambeke, Shannon N. Bennett, Durrell D. Kapan
2010 Tropical medicine & international health  
Vector-borne diseases persist in transmission systems that usually comprise heterogeneously distributed vectors and hosts leading to a highly heterogeneous case distribution.  ...  We focus on the risk of exposure for dengue transmission on the Hawaiian island of Oahu, where the vector Aedes albopictus is well established and areas of dense human population exist.  ...  Acknowledgments The authors wish to thank Pingjun Yang from the Hawai'i Department of Health for providing the mosquito trapping data, and Jon Winchester for helping with retrieving the data, for providing  ... 
doi:10.1111/j.1365-3156.2010.02671.x pmid:21073638 pmcid:PMC3049840 fatcat:d7l4m6yurbesnkj24qzm2zfl4y

Natural, Persistent Oscillations in a Spatial Multi-Strain Disease System with Application to Dengue

José Lourenço, Mario Recker, Mercedes Pascual
2013 PLoS Computational Biology  
Here, with specific reference to dengue, we show how spatially explicit, multi-strain systems can exhibit all of the described epidemiological dynamics even in the absence of immune competition.  ...  Instead, amplification of natural stochastic differences in disease transmission, can give rise to persistent oscillations comprising semi-regular epidemic outbreaks and sequential dominance of dengue's  ...  Author Contributions Conceived and designed the experiments: JL MR. Performed the experiments: JL. Wrote the paper: JL MR.  ... 
doi:10.1371/journal.pcbi.1003308 pmid:24204241 pmcid:PMC3812071 fatcat:brrnwxpewfb43hagjvds636qye

Fine-Scale Variation in Vector Host Use and Force of Infection Drive Localized Patterns of West Nile Virus Transmission

Gabriel L. Hamer, Luis F. Chaves, Tavis K. Anderson, Uriel D. Kitron, Jeffrey D. Brawn, Marilyn O. Ruiz, Scott R. Loss, Edward D. Walker, Tony L. Goldberg, Rick Edward Paul
2011 PLoS ONE  
Rather, robust assessment of local transmission risk should incorporate heterogeneity in vector host feeding and variation in vertebrate reservoir competence at the spatial scale of vector-host interaction  ...  The influence of host diversity on multi-host pathogen transmission and persistence can be confounded by the large number of species and biological interactions that can characterize many transmission  ...  Acknowledgments We thank the Village of Oak Lawn for providing field laboratory facilities and other municipalities (Evergreen Park, Palos Hills, Burbank, Alsip, Author Contributions Conceived and designed  ... 
doi:10.1371/journal.pone.0023767 pmid:21886821 pmcid:PMC3158794 fatcat:fh5juqwjmnaz7azwydk4alykdy

Local and regional dynamics of chikungunya virus transmission in Colombia: the role of mismatched spatial heterogeneity

Sean M. Moore, Quirine A. ten Bosch, Amir S. Siraj, K. James Soda, Guido España, Alfonso Campo, Sara Gómez, Daniela Salas, Benoit Raybaud, Edward Wenger, Philip Welkhoff, T. Alex Perkins
2018 BMC Medicine  
Motivated by an abundance of literature suggesting that the transmission of this mosquito-borne pathogen is localized at scales much finer than nationally, we fitted models at three different spatial scales  ...  Mathematical models of transmission dynamics are routinely fitted to epidemiological time series, which must inevitably be aggregated at some spatial scale.  ...  Availability of data and materials The data sets and code used in the analysis are available at https://github.com/ mooresea/chikv-colombia-emod.  ... 
doi:10.1186/s12916-018-1127-2 pmid:30157921 fatcat:6socvy3b7bhk7pofuhjtyjgc4e

Decelerating Spread of West Nile Virus by Percolation in a Heterogeneous Urban Landscape

Krisztian Magori, Waheed I. Bajwa, Sarah Bowden, John M. Drake, Mercedes Pascual
2011 PLoS Computational Biology  
which pathogens propagate, and also thereby affect the epidemiological patterns of disease at multiple spatial scales.  ...  To further explain these patterns, we developed a spatial model for vector-borne disease transmission in a heterogeneous environment.  ...  We also thank Chris Michael, mathematics teacher at Brookwood High School, Gwinnett County, GA, for his assistance in the early development of the spatial model of WNV transmission.  ... 
doi:10.1371/journal.pcbi.1002104 pmid:21829332 pmcid:PMC3145642 fatcat:qenhnx76vnagncskapsxst2b2e

The Effects of Vector Movement and Distribution in a Mathematical Model of Dengue Transmission

Dennis L. Chao, Ira M. Longini, M. Elizabeth Halloran, Alessandro Vespignani
2013 PLoS ONE  
Two assumptions usually incorporated by mathematical models of vector-borne disease transmission is homogeneous mixing among the hosts and vectors and homogeneous distribution of the vectors.  ...  Methodology/Principal Findings: We explored the effects of mosquito movement and distribution in an individual-based model of dengue transmission in which humans and mosquitoes are explicitly represented  ...  deterministic compartmental models of vector-borne pathogens [4, 5] .  ... 
doi:10.1371/journal.pone.0076044 pmid:24204590 pmcid:PMC3804532 fatcat:z7thelul5vhvhhyxxlwtmmxcry

Big city, small world: density, contact rates, and transmission of dengue across Pakistan

M. U. G. Kraemer, T. A. Perkins, D. A. T. Cummings, R. Zakar, S. I. Hay, D. L. Smith, R. C. Reiner
2015 Journal of the Royal Society Interface  
We furthermore show that neglecting spatial variation in mixing can lead to substantial underestimates of the level of effort needed to control a pathogen with vaccines or other interventions.  ...  Here, we fitted a mathematical model of dengue virus transmission to spatial time-series data from Pakistan and compared maximum-likelihood estimates of 'mixing parameters' when disaggregating data across  ...  The authors thank the WHO Punjab office, Health Department Punjab and PID for providing the epidemiological data, and all participants that helped collect the data.  ... 
doi:10.1098/rsif.2015.0468 pmid:26468065 pmcid:PMC4614486 fatcat:inop4xpglvetxdgy2tih4dft7y
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