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Heritability of head motion during resting state functional MRI in 462 healthy twins

Baptiste Couvy-Duchesne, Gabriëlla A.M. Blokland, Ian B. Hickie, Paul M. Thompson, Nicholas G. Martin, Greig I. de Zubicaray, Katie L. McMahon, Margaret J. Wright
2014 NeuroImage  
Here we investigate whether HM during resting state functional MRI (RS-fMRI) is influenced by genetic factors in a sample of 462 twins (65% female; 101 MZ (monozygotic) and 130 DZ (dizygotic) twin pairs  ...  Head motion (HM) is a critical confounding factor in functional MRI.  ...  We are very grateful to the twins for their generosity of time and willingness to participate in our studies.  ... 
doi:10.1016/j.neuroimage.2014.08.010 pmid:25132021 pmcid:PMC4252775 fatcat:yf7cchb6nzffbihciufvxqh7fq

Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index

Karen Hodgson, Russell A Poldrack, Joanne E Curran, Emma E Knowles, Samuel Mathias, Harald HH Göring, Nailin Yao, Rene L Olvera, Peter T Fox, Laura Almasy, Ravi Duggirala, Deanna M Barch (+2 others)
2016 Cerebral Cortex  
Using data from a large randomly ascertained extended pedigree sample of Mexican Americans (n = 689), we modeled the genetic structure of head motion during resting state fMRI and its relation to 48 other  ...  Head movements during functional magnetic resonance imaging (fMRI) can be detected in all subjects, even with head restraint.  ...  Notes We are grateful to all of the participants involved in the Genetics of Brain Structure and Function Study and the Human Connectome Project. Conflict of Interest: None declared.  ... 
doi:10.1093/cercor/bhw321 pmid:27744290 fatcat:5l37z25m6bbgnigntrrhdk5snu

Inheritance of neural substrates for motivation and pleasure experience [article]

Zhi Li, Yi Wang, Chao Yan, Ke Li, Ya-wei Zeng, Eric F C Cheung, Anna R Docherty, Pak C Sham, Raquel E Gur, Ruben C Gur, Raymond C K Chan
2018 bioRxiv   pre-print
In the present study, a Monetary Incentive Delay (MID) task was used to examine the haemodynamic activation of the nucleus accumbens (NAcc), a key hub of the reward system, in 86 healthy monozygotic twins  ...  and 88 dizygotic twins during the anticipation of monetary incentives.  ...  Stokes and 221 colleagues (2013) reported a significant heritability estimate of 0.21 for 222 dopaminergic activities of the right ventral striatum in the resting state.  ... 
doi:10.1101/294090 fatcat:5s5wzoei5rfmbgphghmi7o7a3y

General Functional Connectivity: shared features of resting-state and task fMRI drive reliable individual differences in functional brain networks [article]

Maxwell L Elliott, Annchen R Knodt, M. Justin Kim, Tracy R Melzer, Ross Keenan, David Ireland, Sandhya Ramrakha, Richie Poulton, Avshalom Caspi, Terrie E Moffitt, Ahmad R Hariri
2018 bioRxiv   pre-print
Intrinsic connectivity, commonly measured using resting-state fMRI, has emerged as a fundamental feature of the brain.  ...  We further demonstrate that the increase in reliability gained through GFC boosts predictive utility by accounting for upwards of 200% more variance in the domain of intelligence.  ...  Functional MRI was collected during resting-state and four tasks with a series 203 of 72 interleaved axial T2-weighted functional slices acquired using a 3-fold multi-band 204 accelerated echo planar imaging  ... 
doi:10.1101/330530 fatcat:drygm7p5xzhllopi6g6nq3dgla

Archetypes in human behavior and their brain correlates: An evolutionary trade-off approach [article]

Giorgia F Cona, Loren Kocillari, Alessandro Palombit, Alessandra Bertoldo, Amos Maritan, Maurizio Corbetta
2018 bioRxiv   pre-print
Time preference for reward identified three archetypes, which accounted for variability on many cognitive, personality, and socio-economic status scores, differences in brain structure, as well as in functional  ...  Among all possible 300 combinations of pairs of traits, we found the best fit to Pareto optimality when individuals were plotted in the trait-space of time preferences for reward, evaluated with the Delay  ...  Resting-State Functional Connectivity Predicts Impulsivity in Economic 858 Decision-Making. J.  ... 
doi:10.1101/325803 fatcat:2apropjfh5dfhna6nzkbmma54i

Obesity gene NEGR1 associated with white matter integrity in healthy young adults

Emily L. Dennis, Neda Jahanshad, Meredith N. Braskie, Nicholus M. Warstadt, Derrek P. Hibar, Omid Kohannim, Talia M. Nir, Katie L. McMahon, Greig I. de Zubicaray, Grant W. Montgomery, Nicholas G. Martin, Arthur W. Toga (+2 others)
2014 NeuroImage  
microstructural properties, assessed by high angular resolution diffusion imaging (HARDI) in young healthy adults between 20 and 30 years of age from the Queensland Twin Imaging study (QTIM).  ...  As our subjects were young and healthy, our results suggest that NEGR1 has effects on brain structure independent of its effect on obesity.  ...  motion in a diffusion MRI study.  ... 
doi:10.1016/j.neuroimage.2014.07.041 pmid:25072390 pmcid:PMC4269485 fatcat:2qyuyd4hmrctznzxhavmnawyci

ePresentation Sessions

2018 European Journal of Neurology  
Methods: Ninety-four AD patients, 47 aMCI patients (25 c-aMCI within 36 months) and 53 healthy controls underwent 3D T1-weighted, diffusion tensor and resting state functional MRI.  ...  We aimed to investigate the functional connectivity of the SMA in de novo PD patients with and without fatigue, by using a seed-based resting-state functional MRI.  ...  Results: The heritability of AAO was high in FTD caused by C9ORF72 repeat expansions, and to a lesser degree in GRN families.  ... 
doi:10.1111/ene.13700 fatcat:xk5co6xixzbs3n7wnhc5xjkpv4

3rd International Congress on Neurology and Epidemiology. Abu Dhabi, UAE, November 21–23, 2013: Abstracts

2013 Neuroepidemiology  
HERITABILITY -TWIN STUDY Knezevic-Pogancev M.  ...  TCD to detect PFO during normal respiration (rest) and during the Valsalva maneuver (VM) were recruited in the study.  ...  exploration of patients with epilepsy (SEEG) or in morphological and functional imaging. 2) For microsurgical approach of Insula using Neuronavigation techniques. 3) Identification of Insula during stereotactic  ... 
doi:10.1159/000356326 fatcat:cwvmef3j4bgbxctcrlbsfml4da

ECR 2011 Book of Abstracts - B - Scientific Sessions

2011 Insights into Imaging  
CT started 18 seconds after 140 HU threshold was reached in the abdominal aorta after intravenous contrast injection (370-400 mg I/mL, 4 mL/sec at 2 mL/kg followed by 50 mL of saline flush).  ...  Results: In 20 HCCs concordant hypervascular profile was shown between CT and MR during the arterial phase, while discordant vascularity profile was identified in 11 nodules appearing isovascular on CT  ...  by velocity encoded cine MRI at rest and during cold pressor test (CPT).  ... 
doi:10.1007/s13244-011-0077-4 pmid:23100071 pmcid:PMC3533624 fatcat:lytbu2vohbhhnorjqlpogl77iu

Cervical Spine: The Surgical Treatment of Painful Disorders

2009 European spine journal  
Study design/setting: Prospective study of 87 CDA patients treated in either of two FDA investigational device exemption studies at a single site between 2003 and 2008.  ...  Less evident, however, is the efficacy of CDA for patients in this group with predominant axial neck pain.  ...  We have shown previously using volunteer healthy middle aged twins that DDD is highly heritable and that DDD as determined by MRI scan is a predictor of low back pain (LBP).  ... 
doi:10.1007/s00586-009-1102-x pmid:19727857 fatcat:ymmeaxt72naffjyfequhqbk3eu

Subject index: Abstracts

1993 Journal of the American College of Cardiology  
945·50. 400A Efficacy of Ventricular Suction During Rapid Filling in the Normal Human Heart 945·53. 40lA Endurance Exercise Training Augments Diastolic Filling at Rest and During Exercise in Healthy Older  ...  Lipoprotein Cholesterol in Hypertriglyceridemia 801·2. 379A Heritability of the Quantitative Lipoprotein(a) Trait in Monozygotic Twin Pairs 819·6. 431A Hypolipidemic Effects of Fish Oil Compared to  ... 
doi:10.1016/s0735-1097(10)80312-2 fatcat:it6q4uxdhvc4jghxldtyvubrja

2nd European Headache and Migraine Trust International Congress-EHMTIC

2010 The Journal of Headache and Pain  
Materials Resting state (RS) functional MRI data were acquired from 87 migraine patients (43 with aura, 38 with WMHs) and 25 matched healthy controls (HC).  ...  Twin studies indicate that migraine has a significant genetic component, with heritability estimates of 33-65%.  ...  A MRI and angio-RMI of the brain was performed in february 2009, showing a small, right intracranial carotid artery aneurysm.  ... 
doi:10.1007/s10194-010-0259-3 pmid:21049310 pmcid:PMC3639733 fatcat:tkg2xwo5jjau5hbxgi4a2u2lpa

Poster Session III-Wednesday

2013 Neuropsychopharmacology  
tions about the sensory effects of meditation may be warranted. Abstracts S436 ACNP 52nd Annual Conference  ...  A subset of 220 twin pairs (60 MZ and 160 DZ) were collected and used for heritability analysis.  ...  Twin analyses revealed that OC traits were 65% heritable, with the remainder of the variance mostly accounted for by non-shared environment.  ... 
doi:10.1038/npp.2013.281 fatcat:n2o3tllrsrbyxgzsfwzhl5psua

Ocular Motility Disorders [chapter]

Mitra Maybodi, Richard W. Hertle, Brian N. Bachynski
2003 Pediatric Ophthalmology and Strabismus  
in the brain and spinal cord are varied and complex.  ...  The pathway of saccades originates in the visual cortex and projects through the anterior limb of the internal capsule, through the diencephalon.  ...  Type of eye movement Function Stimulus Clinical tests Vestibular Maintain steady Head rotation Fixate on object while fixation during moving head; calorics head rotation Saccades Rapid refixation  ... 
doi:10.1007/978-0-387-21753-6_48 fatcat:6imaftsafvfvvflfrfhge3ynfa

58th Annual Symposium of the International Society for Clinical Electrophysiology of Vision (ISCEV 2020)

2020 Documenta Ophthalmologica  
All children had neuroimaging (brain MRI) where visual pathway gliomas were searched for, however in two of the children MRI was performed after visual electrodiagnostic evaluation.  ...  In cases with confirmed optic pathway glioma, normal VEP responses might imply intact visual pathway function.  ...  Coefficients of intra-pair correlation were calculated for monozygotic and dizygotic twins and heritability estimated using structural equation modelling.  ... 
doi:10.1007/s10633-020-09789-6 pmid:32915376 fatcat:uwr4pr2ri5ftvmclukvubbkoca
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