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Heritability of brain volume change and its relation to intelligence
2014
NeuroImage
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An association between IQ (available for 91 participants) and brain volume change was observed, which was attributed to genes involved in both the variation in change in brain volume and in intelligence ...
We address the question whether longitudinal changes in brain volume or in surface area in young adults are under genetic control and whether these changes are also related to general cognitive functioning ...
Moreover, brain volume changes in the young adult brain are positively related to intelligence and this association is mediated through genes common to both intelligence and brain volume change. ...
doi:10.1016/j.neuroimage.2014.04.072
pmid:24816534
fatcat:my2a55mr5ffthddtdprrb4k4qa
Genetic influences on human brain structure: A review of brain imaging studies in twins
2007
Human Brain Mapping
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Estimates of genetic and environmental influences on age-related changes in brain structure in children and adults await further longitudinal twin-studies. ...
The high heritability for (global) brain volumes, including the intracranium, total brain, cerebral gray, and white matter, seems to be present throughout life. ...
In adulthood, brain volume continues to change. ...
doi:10.1002/hbm.20398
pmid:17415783
fatcat:5ij6onn35ndjfbcqy7t45vcpmu
Brain Plasticity and Intellectual Ability Are Influenced by Shared Genes
2010
Journal of Neuroscience
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to be heritable and partly related to cognitive ability. ...
Thus, not only does the brain continue to change well into adulthood, these changes are functionally relevant because they are related to intelligence. ...
influences on brain volume and brain volume change. ...
doi:10.1523/jneurosci.5841-09.2010
pmid:20410105
pmcid:PMC6632359
fatcat:dvzn4xk6xfa3zdncmfq3keqv3q
GENETICS OF BRAIN STRUCTURE AND INTELLIGENCE
2005
Annual Review of Neuroscience
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A variety of sophisticated brain-mapping approaches relating genetic influences on brain structure and intelligence establishes a regional distribution for this relationship that is consistent with behavioral ...
Genetic influences on brain morphology and IQ are well studied. ...
grant and the International Consortium for Brain Mapping, funded by the National Institute of Mental Health and the National Institute on Drug Abuse (P20 MH/DA52176). ...
doi:10.1146/annurev.neuro.28.061604.135655
pmid:15651931
fatcat:6dct5ykmijb57jso5zq2xop774
The evolution of human intelligence and the coefficient of additive genetic variance in human brain size
2007
Intelligence
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However, adult human intelligence remains highly heritable, and is genetically correlated with brain size. ...
This result is hard to reconcile with most current theories of human mental evolution, which emphasize directional (more-is-better) selection for higher intelligence and larger brains. ...
Acknowledgements For helpful guidance and feedback, thanks to Rosalind Arden, Steve Gangestad, Linda Gottfredson, Keith Hunley, Earl Hunt, Osbjorn Pearson, Phil Rushton, Randy Thornhill, Ron Yeo, and an ...
doi:10.1016/j.intell.2006.08.008
fatcat:kyj3nbwqvvgfznkzhkxptws2uy
Neurobiology of intelligence: Health implications?
2004
Discovery Medicine
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These exciting scientific advances encourage renewed responsiveness to the social and ethical dimensions of such research, including its health-relevance. ...
Variations in intelligence and brain structure are heritable, but are also influenced by factors such as education, family environment, and environmental hazards. ...
Acknowledgments The preparation of this article was supported in part by research grants from the National Institute of Mental Health (MH66088 to J. R. ...
pmid:20704978
fatcat:i4kki7qjgrbpxnqxj5h3xw4fra
Genetic variation, brain, and intelligence differences
2021
Molecular Psychiatry
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We summarise regional brain imaging associations with intelligence and interpret these with respect to theoretical accounts. ...
Here, we summarise and critique the last 10 years or so of molecular genetic (DNA-based) research on intelligence, including the discovery of genetic loci associated with intelligence, DNA-based heritability ...
Having larger volumes of brain (and tissues therein) appears to be relatively strongly related to having greater numbers of neurons [107] . ...
doi:10.1038/s41380-021-01027-y
pmid:33531661
pmcid:PMC8960418
fatcat:h2hzx6lal5ai3gsndvokusngny
Brain SCALE: Brain Structure and Cognition: an Adolescent Longitudinal Twin Study into the Genetic Etiology of Individual Differences
2012
Twin Research and Human Genetics
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Twin studies are of great value to explore to what extent genetic and environmental factors explain individual differences in brain development and cognition. ...
From childhood into adolescence, the child's brain undergoes considerable changes in both structure and function. ...
Acknowledgments and Funding We would like to thank all the participants for making this study possible. ...
doi:10.1017/thg.2012.4
pmid:22856378
fatcat:lyjkirabuzbavaq3pm355ehesm
Genetic Architecture of Grey Matter - A Review
2020
International Journal of Research in Pharmaceutical Sciences
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The present review is to document the deeper understanding of the genetic architecture of grey matter obtained from reliable sources of information which are associated with grey matter density and volume ...
The literature search on genetic architecture was carried out for papers published by google scholar and PubMed with the intention of retrieving all original reports that were relevant to it. ...
Grey matter density and volume link with higher standards of intelligent scores developed with age in healthy children for intelligent scores. ...
doi:10.26452/ijrps.v11ispl3.2929
fatcat:sfqhapytsnfodev2hjyg74mtaa
The obese brain as a heritable phenotype: a combined morphometry and twin study
2016
International Journal of Obesity
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Background-Body weight and adiposity are heritable traits. To date it remains unknown whether obesity-associated brain structural alterations are under a similar level of genetic control. ...
Twin data were analyzed by applying the additive genetic, common environmental and residual effects (ACE) model to determine heritability of brain regions that were associated with BMI. ...
It is possible that at least some regional brain volume differences reflect central endophenotypes leading to unhealthy eating and excess adiposity. ...
doi:10.1038/ijo.2016.222
pmid:27916985
pmcid:PMC5402354
fatcat:oo2urm4jxvfrbegcpjlu6e6k7q
Genes contributing to subcortical volumes and intellectual ability implicate the thalamus
2013
Human Brain Mapping
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It has been shown that brain volume and general intellectual ability are to a significant extent influenced by the same genetic factors. ...
This genetic factor is also implicated in cerebral brain volume. The thalamus, with its widespread cortical connections, may thus play a key role in human intelligence. ...
INTRODUCTION Understanding the relative influences of genes and environment on differences in human brain structure is of key importance for understanding the dynamics of brain devel-opment and its relation ...
doi:10.1002/hbm.22356
pmid:24038793
fatcat:pd2n3mkyivhv7ooqvmzinzrue4
Genes, Evolution and Intelligence
2014
Behavior Genetics
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A review of a large body of evidence demonstrates that there is a g factor in a wide range of species and that, in the species studied, it relates to brain size and is heritable. ...
I briefly discuss the evidence regarding the relationship of brain size to intelligence. ...
Energetics: the expensive tissue hypothesis Apart from its possible relation to intelligence the evolution of the brain is of interest because of its energetics. ...
doi:10.1007/s10519-014-9646-x
pmid:24604063
fatcat:7ywlstxkqbg7hoc7zxtpk5cgxm
A genetic analysis of brain volumes and IQ in children
2009
Intelligence
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The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes. Crown ...
Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. ...
Acknowledgements We would like to acknowledge the following grants: Quantitative genetic modeling of variation in cognitive brain maturation (NWO 051.02.060, 668.772); Spinozapremie (NWO/SPI 56-464-14192 ...
doi:10.1016/j.intell.2008.10.005
fatcat:ki7bpxo5nfb4vbzkh5jpwgx64q
Intelligence and brain size in 100 postmortem brains: sex, lateralization and age factors
2005
Brain
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The study of intelligence in relation to postmortem cerebral volume is not available to date. ...
Numerous studies relating measures of brain size such as brain weight, head circumference, CT or MRI brain volume to different intelligence test measures, with variously defined samples of subjects have ...
We are indebted to the patients and their families for their contribution and to the oncologists, pathologists, medical and nursing staff and administrators of McMaster University and Hamilton Health Sciences ...
doi:10.1093/brain/awh696
pmid:16339797
fatcat:hmnscshmfrdbtkgimehhdjulpy
Genetics of intelligence
2006
European Journal of Human Genetics
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Special mention is also made of multivariate studies that examine the genetic correlation between intelligence test scores and their correlates such as processing speed, birth weight and brain size. ...
This article provides an overview of the biometric and molecular genetic studies of human psychometric intelligence. ...
Acknowledgements Ian J Deary is the recipient of a Royal Society-Wolfson Research Merit Award. ...
doi:10.1038/sj.ejhg.5201588
pmid:16721405
fatcat:yzuj3d4mibbovl4ojrsrgydyku
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