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Heritability of DTI and MTR in nine-year-old children

Rachel M. Brouwer, René C.W. Mandl, Jiska S. Peper, G. Caroline M. van Baal, René S. Kahn, Dorret I. Boomsma, Hilleke E. Hulshoff Pol
<span title="">2010</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
, in a sample of 185 nine-year old children from monozygotic and dizygotic twin pairs.  ...  ) underlie these traits at nine years of age.  ...  The aim of this study was to disentangle influences of genetic and environmental factors on variation in diffusion parameters and MTR in a sample of 185 nine-year-old twins.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2010.03.017">doi:10.1016/j.neuroimage.2010.03.017</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20298793">pmid:20298793</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/43elaczaozehleplhhgnjktsg4">fatcat:43elaczaozehleplhhgnjktsg4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170812040218/http://www.tweelingenregister.org/fileadmin/user_upload/publicaties/verslaggeving/NTR-publicaties_2010/Brouwer_NI_2010.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/2f/ff/2fff46f8953c53ce91808ff847ccc0d30a696e9a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2010.03.017"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a>

Brain SCALE: Brain Structure and Cognition: an Adolescent Longitudinal Twin Study into the Genetic Etiology of Individual Differences

Inge L. C. van Soelen, Rachel M. Brouwer, Jiska S. Peper, Marieke van Leeuwen, Marinka M. G. Koenis, Toos C. E. M. van Beijsterveldt, Suzanne C. Swagerman, René S. Kahn, Hilleke E. Hulshoff Pol, Dorret I. Boomsma
<span title="">2012</span> <i title="Cambridge University Press (CUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/u7my2wkygjamrjaxyx22iv3kuq" style="color: black;">Twin Research and Human Genetics</a> </i> &nbsp;
The participants were recruited from The Netherlands Twin Register (NTR) and at baseline consisted of 112 families, with 9-year-old twins and an older sibling.  ...  Participants will return for a third assessment when the twins are around 16 years old.  ...  Acknowledgments and Funding We would like to thank all the participants for making this study possible.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1017/thg.2012.4">doi:10.1017/thg.2012.4</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22856378">pmid:22856378</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lyjkirabuzbavaq3pm355ehesm">fatcat:lyjkirabuzbavaq3pm355ehesm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170812040206/http://www.tweelingenregister.org/2012/Soelen_TRHG_2012.pdf?origin=publication_detail" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c5/8d/c58d3bf001556a452d947f01821eabaaed06f985.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1017/thg.2012.4"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> cambridge.org </button> </a>

Large-scale neuroimaging and genetic study reveals genetic architecture of brain white matter microstructure [article]

Bingxin Zhao, Jingwen Zhang, Joseph Ibrahim, Rebecca Santelli, Yun Li, Tengfei Li, Yue Shan, Ziliang Zhu, Fan Zhou, Huiling Liao, Thomas Nichols, Hongtu Zhu
<span title="2018-03-25">2018</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Heritability of structural changes of WM tracts has been examined using diffusion tensor imaging (DTI) in family-based studies for different age groups.  ...  Here, we analyzed the genetic architecture of WM tracts using DTI and single-nucleotide polymorphism (SNP) data of unrelated individuals in the UK Biobank (n ~ 8000).  ...  Heritability of DTI and MTR in nine-year-old children. Neuroimage. 2010;53(3):1085-92. 21. Brouwer RM, Mandl RC, Schnack HG, van Soelen IL, van Baal GC, Peper JS, et al.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/288555">doi:10.1101/288555</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/viianp24kjhaxd6ouwvl7sjn6u">fatcat:viianp24kjhaxd6ouwvl7sjn6u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200711152622/https://www.biorxiv.org/content/biorxiv/early/2018/03/26/288555.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/7f/f8/7ff805e74ecc9423885e36993691c6276c862c2f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/288555"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Abstracts Presented at the Thirty–Fourth Annual International Neuropsychological Society Conference, February 1–4, 2006, Boston, Massachussetts, USA

<span title="">2006</span> <i title="Cambridge University Press (CUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/xvr5kau3hzbntoja7v53bdyqga" style="color: black;">Journal of the International Neuropsychological Society</a> </i> &nbsp;
Results : Using ANCOVA, TOMM scores accounted for a significant amount of variance in test performance on Digit Span and all subtests of the CVLT-II (η 2 ranged from .133 to .248), but not Trails A or  ...  Effort and Cognition in Persistently Psychiatrically Disabled Patients. Objective: Recent research suggests poor mental effort is a core feature of schizophrenia.  ...  Participants and Methods : Fifty-nine children between the ages of three and fourteen years (M = 7.39 years) were administered select SB-IV subtests.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1017/s1355617706069918">doi:10.1017/s1355617706069918</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cy3cbwlgrvccfnn6w7inplceni">fatcat:cy3cbwlgrvccfnn6w7inplceni</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180728123129/https://www.cambridge.org/core/services/aop-cambridge-core/content/view/17AD79F8CF8A9764D3D365008D32FFF1/S1355617706069918a.pdf/div-class-title-abstracts-presented-at-the-thirty-fourth-annual-international-neuropsychological-society-conference-february-1-4-2006-boston-massachussetts-usa-div.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1017/s1355617706069918"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> cambridge.org </button> </a>

Final Program, The International Neuropsychological Society, Federation of Spanish Societies of Neuropsychology, Spanish Neuropsychological Society, Spanish Psychiatry Society Joint Mid-Year Meeting, July 4-7, 2007 Bilbao, Spain

<span title="2007-08-15">2007</span> <i title="Cambridge University Press (CUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/xvr5kau3hzbntoja7v53bdyqga" style="color: black;">Journal of the International Neuropsychological Society</a> </i> &nbsp;
method which allows measurements of the concentration of oxygenated (oxy-Hb), and deoxygenated (deoxy-Hb) hemoglobin in the cortex.  ...  The aim of the present study was to analyse the usefulness of the 15OT to assess visual agnosia in preclinical and mild Alzheimer's disease (AD).  ...  With, approximately, twenty children (2-11 years old) in each institution.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1017/s1355617707071408">doi:10.1017/s1355617707071408</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ecyaxaxu6jf4pkcc3wdaxqiirm">fatcat:ecyaxaxu6jf4pkcc3wdaxqiirm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180727131104/https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FBEB0FA75499E44C99302ADD63D2739B/S1355617707071408a.pdf/div-class-title-final-program-the-international-neuropsychological-society-federation-of-spanish-societies-of-neuropsychology-spanish-neuropsychological-society-spanish-psychiatry-society-joint-mid-year-meeting-july-4-7-2007-bilbao-spain-div.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1017/s1355617707071408"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> cambridge.org </button> </a>

Poster Session I

<span title="2013-11-27">2013</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zscwnf3bera7vcvkm7bgnh2sbu" style="color: black;">Neuropsychopharmacology</a> </i> &nbsp;
Results: Thirty-five subjects with a mean age of 50±9 years and 70% Caucasian.  ...  KYNA-based animal model of SZ; and (3) the relative roles of a7nAChRs vs NMDA receptors in performance in the DNMTP task.To this end, we determined, in a separate group of intact animals, the effects  ...  Abi-Dargham, and S. Kapur, Arch Gen Psychiatry 69, 776 (2012). 2  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/npp.2013.279">doi:10.1038/npp.2013.279</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/54ipecxjarcvljrvn5fgtgif5u">fatcat:54ipecxjarcvljrvn5fgtgif5u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210718015520/https://www.nature.com/articles/npp2013279.pdf?error=cookies_not_supported&amp;code=31be8f77-bd08-403b-b711-28a3082f8064" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/npp.2013.279"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

2014 Joint ACTRIMS-ECTRIMS Meeting (MSBoston 2014): Oral Presentations

<span title="">2014</span> <i title="SAGE Publications"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kulx3aann5brlm7mg2jhcm6puq" style="color: black;">Multiple Sclerosis</a> </i> &nbsp;
However, the importance of IL-17 in MS is still under debate, and other TH17-associated cytokines are likely more crucial in the initiation and maintenance of neuroinflammation.  ...  ELISA was used to determine expression of IL-26 in serum and cerebrospinal fluid (CSF) of MS patients and controls, and to analyze supernatant of human blood brain barrier endothelial cells (BBB-ECs) after  ...  We compared children who had a parent with MS, were born between 1999 and 2006, and had an EDI assessment to children with parents not affected with MS, who were matched on sex, region and year of the  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1177/1352458514546076">doi:10.1177/1352458514546076</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25205047">pmid:25205047</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4518813/">pmcid:PMC4518813</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/5giyc6lpwrdhzgjat3fhfcfcmi">fatcat:5giyc6lpwrdhzgjat3fhfcfcmi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190302223309/http://pdfs.semanticscholar.org/bdc7/e1989a40ac8acd83f35c4311b10b2ebc0c84.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/bd/c7/bdc7e1989a40ac8acd83f35c4311b10b2ebc0c84.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1177/1352458514546076"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> sagepub.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518813" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

SCIENTIFIC POSTERS

<span title="2006-08-18">2006</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/na5fvete3zgchm7q2aibnq2yhm" style="color: black;">Neuroradiology</a> </i> &nbsp;
PURPOSE Medical complications after SAH include fever, anemia requiring transfusion, hyperglycemia, electrolyte abnormalities, pneumonia, hypertension, and neurogenic stunned myocardium and pulmonary  ...  MATERIAL AND METHODS Sixty nine years old male was admitted to the hospital due to consciousness disturbance and mental retardation for a month.  ...  in a 29 year-old patient with an occipital fracture.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s00234-006-0139-3">doi:10.1007/s00234-006-0139-3</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/hv57hmgk6jchtk65tdirm35j4y">fatcat:hv57hmgk6jchtk65tdirm35j4y</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171011050350/http://publisher-connector.core.ac.uk/resourcesync/data/Springer-OA/pdf/378/aHR0cDovL2xpbmsuc3ByaW5nZXIuY29tLzEwLjEwMDcvczAwMjM0LTAwNi0wMTM5LTMucGRm.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/51/3a/513a64aeb04148e5609a7a1f5b3be7cf7a5a4d70.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s00234-006-0139-3"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>

Poster Session II

<span title="">2010</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zscwnf3bera7vcvkm7bgnh2sbu" style="color: black;">Neuropsychopharmacology</a> </i> &nbsp;
used cannabis for the first time in 2007; of them 62.2% were less than 18 years old.  ...  Results: All nine neurophysiological and neurocognitive measures were found to be significantly heritable in this sample.  ...  A recent example is the old russian drug Dimebon (latrepirdine), which has shown in a phase II trial in AD patients substantial clinical benefit.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/npp.2010.217">doi:10.1038/npp.2010.217</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/gbcgyi35jbdndlwhlgwio7ts7y">fatcat:gbcgyi35jbdndlwhlgwio7ts7y</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200510114937/https://www.nature.com/articles/npp2010217.pdf?error=cookies_not_supported&amp;code=b01274f5-97bd-40ed-9a00-a38c06dd9d10" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/7d/14/7d1420a42d8c6d208f907b10e0291fd6203a989b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/npp.2010.217"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Annual Symposium of the Society for the Study of Inborn Errors of Metabolism

<span title="2011-07-26">2011</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/mnjppdkmkret5due3avrfwvu7y" style="color: black;">Journal of Inherited Metabolic Disease</a> </i> &nbsp;
Background: Tandem mass spectrometry (LCMS/MS) is rapidly being adopted to screen dried blood spots for many of metabolic diseases in a single assay.  ...  Conclusions: In screening for 75 metabolic disorders by LCMS/MS, a mean positive predictive value of 8% can be achieved when using cutoffs for individual markers determined empirically on babies.  ...  and MTR genes causing homocystinuria.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10545-011-9371-z">doi:10.1007/s10545-011-9371-z</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/iixkoiysuzhobc2gk2hw2pk6sq">fatcat:iixkoiysuzhobc2gk2hw2pk6sq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20130101044102/http://link.springer.com:80/content/pdf/10.1007/s10545-011-9371-z" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10545-011-9371-z"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>

Panel Session Co-Morbid Pain and Addiction: Novel Treatments

<span title="2006-11-16">2006</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zscwnf3bera7vcvkm7bgnh2sbu" style="color: black;">Neuropsychopharmacology</a> </i> &nbsp;
Results: Nine barriers were identified including absence of specific molecular pathology knowledge, the influence of the disease entity paradigm, misinterpretation of antipsychotic drug effects on schizophrenia  ...  The relevance of this upregulation and the failure of it in schizophrenia in relation to clinical symptoms and cognitive deficits is not yet known.  ...  The Time Course of Antipsychotics Versus Placebo: On Overall Efficacy, Positive, Negative and Cognitive Symptoms John M. Davis*  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/sj.npp.1301265">doi:10.1038/sj.npp.1301265</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/6odqjmshuncm5muxk5g5knprui">fatcat:6odqjmshuncm5muxk5g5knprui</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200510090208/https://www.nature.com/articles/1301265.pdf?error=cookies_not_supported&amp;code=2bcb475a-7c8a-432b-8421-2fbdbd1e17d8" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b7/26/b726cf9864cee9582f2e8ca1efa321162d00a3b2.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/sj.npp.1301265"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Poster Session II / Thursday, 31 May 2007

<span title="">2007</span> <i title="S. Karger AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/43rsh2kahvc6digemicmi5ae3e" style="color: black;">Cerebrovascular Diseases</a> </i> &nbsp;
The corresponding rates declined from to 23 to 18, 10 and 8 per 10,000 person years for FEV, or 19,15,14 and 10 for FEV as percent of FVC, in the 1st,2nd,3rd, and 4th quartiles, respectively (P for trend  ...  For quartiles of VC, as % of age and height predicted level, there was a modest gradient of fatal stroke (18,16,14 and 13 per 10,000 person-years) which was erased upon age-adjustment.  ...  The mean age was 64.0 ± 11.0 years (range 35.5 to 82.4). Fifty-nine or 63% of patients were men, 69% had a Charlson comorbidity index of 0, 27% 1, and 4% 2.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1159/000103855">doi:10.1159/000103855</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/t3rudj4am5bedhko32y7sqgxsu">fatcat:t3rudj4am5bedhko32y7sqgxsu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180725224948/https://www.karger.com/Article/Pdf/103855" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/fc/52/fc52f5f52152999672976090128e1a280c1add4b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1159/000103855"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>