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MMST zur Überlebensprognostik bei Demenz

Sebastian Hötte, Daniel Lankers, Sebastian Kissler, Harald-Jürgen Freyberger, Stefan Schröder
2010 Psychiatrische Praxis  
Hötte Sebastian Dirk MMST zur Überlebensprognostik bei Demenz -8-Jahre-Follow-Up-Studie bei 145 ambulanten Demenzpatienten Problem: Inwieweit sich Überlebenszeiten bei Demenz aus dem Punktwert des Mini-Mental Status Tests (MMST) für individuelle, aber auch für versorgungsmedizinische Planung berechnen lassen, ist Thema dieser Studie.
doi:10.1055/s-0029-1223473 pmid:20183772 fatcat:hqbic3jsarbjddp5v3nxblfqse

The unspoken secret: sexual violence in World War II

PHILIPP KUWERT, HARALD JÜRGEN FREYBERGER
2007 International Psychogeriatrics  
War is a complex, enduring trauma composed of variable forms of extreme stress, such as violence, fear of death, displacement, loss of family members, abuse and starvation (Berman, 2001) . More than 90% of war victims are civilians (UNICEF, 2006) . Children and women are extremely vulnerable to traumatic experiences in times of war and the risk continues even in post-war-situations (Shanks and Schull, 2000) . As far as former war-children are concerned, a high https://www.cambridge.org/core/terms.
doi:10.1017/s1041610207005376 fatcat:to4jex4bsfa6dpqhsvhgyjt22q

Life- and person-centred help in Mecklenburg-Western Pomerania, Germany (DelpHi): study protocol for a randomised controlled trial

Jochen René Thyrian, Thomas Fiß, Adina Dreier, Georgia Böwing, Aniela Angelow, Sven Lueke, Stefan Teipel, Steffen Fleßa, Hans Jörgen Grabe, Harald Jürgen Freyberger, Wolfgang Hoffmann
2012 Trials  
The provision of appropriate medical and nursing care for people with dementia is a major challenge for the healthcare system in Germany. New models of healthcare provision need to be developed, tested and implemented on the population level. Trials in which collaborative care for dementia in the primary care setting were studied have demonstrated its effectiveness. These studies have been conducted in different healthcare systems, however, so it is unclear whether these results extend to the
more » ... ecific context of the German healthcare system. The objective of this population-based intervention trial in the primary care setting is to test the efficacy and efficiency of implementing a subsidiary support system on a population level for persons with dementia who live at home. Methods and study design: The study was designed to assemble a general physician-based epidemiological cohort of people above the age of 70 who live at home (DelpHi cohort). These people are screened for eligibility to participate in a trial of dementia care management (DelpHi trial). The trial is a cluster-randomised, controlled intervention trial with two arms (intervention and control) designed to test the efficacy and efficiency of implementing a subsidiary support system for persons with dementia who live at home. This subsidiary support system is initiated and coordinated by a dementia care manager: a nurse with dementia-specific qualifications who delivers the intervention according to a systematic, detailed protocol. The primary outcome is quality of life and healthcare for patients with dementia and their caregivers. This is a multidimensional outcome with a focus on four dimensions: (1) quality of life, (2) caregiver burden, (3) behavioural and psychological symptoms of dementia and (4) pharmacotherapy with an antidementia drug and prevention or suspension of potentially inappropriate medication. Secondary outcomes include the assessment of dementia syndromes, activities of daily living, social support health status, utilisation of health care resources and medication. Discussion: The results will provide evidence for specific needs in ambulatory care for persons with dementia and will show effective ways to meet those needs. Qualification requirements will be evaluated, and the results will help to modify existing guidelines and treatment paths. Trial registration: NCT01401582
doi:10.1186/1745-6215-13-56 pmid:22575023 pmcid:PMC3482148 fatcat:6l3gyp64ozafxedblnicdm5dpa

Assessment of subjective emotional valence and long-lasting impact of life events

Johanna König, Andrea Block, Matthias Becker, Kristin Fenske, Johannes Hertel, Sandra Van der Auwera, Kathleen Zymara, Henry Völzke, Harald Jürgen Freyberger, Hans Jörgen Grabe
2020 Postprints der Universität Potsdam: Humanwissenschaftliche Reihe  
Life events (LEs) are associated with future physical and mental health. They are crucial for understanding the pathways to mental disorders as well as the interactions with biological parameters. However, deeper insight is needed into the complex interplay between the type of LE, its subjective evaluation and accompanying factors such as social support. The "Stralsund Life Event List" (SEL) was developed to facilitate this research. Methods: The SEL is a standardized interview that assesses
more » ... time of occurrence and frequency of 81 LEs, their subjective emotional valence, the perceived social support during the LE experience and the impact of past LEs on present life. Data from 2265 subjects from the general population-based cohort study "Study of Health in Pomerania" (SHIP) were analysed. Based on the mean emotional valence ratings of the whole sample, LEs were categorized as "positive" or "negative". For verification, the SEL was related to lifetime major depressive disorder (MDD; Munich Composite International Diagnostic Interview), childhood trauma (Childhood Trauma Questionnaire), resilience (Resilience Scale) and subjective health (SF-12 Health Survey). Results: The report of lifetime MDD was associated with more negative emotional valence ratings of negative LEs (OR = 2.96, p < 0.0001). Negative LEs (b = 0.071, p < 0.0001, beta = 0.25) and more negative emotional valence ratings of positive LEs (b = 3.74, p < 0.0001, beta = 0.11) were positively associated with childhood trauma. In contrast, more positive emotional valence ratings of positive LEs were associated with higher resilience (b = -7.05, p < 0.0001, beta = 0.13), and a lower present impact of past negative LEs was associated with better subjective health (b = 2.79, p = 0.001, beta = 0.05). The internal consistency of the generated scores varied considerably, but the mean value was acceptable (averaged Cronbach's alpha > 0.75). Conclusions: The SEL is a valid instrument that enables the analysis of the number and freque [...]
doi:10.25932/publishup-45985 fatcat:ysxybv4iarfoxdotkk4q7r727u

Assessment of subjective emotional valence and long-lasting impact of life events: development and psychometrics of the Stralsund Life Event List (SEL)

Johanna König, Andrea Block, Mathias Becker, Kristin Fenske, Johannes Hertel, Sandra Van der Auwera, Kathleen Zymara, Henry Völzke, Harald Jürgen Freyberger, Hans Jörgen Grabe
2018 BMC Psychiatry  
Life events (LEs) are associated with future physical and mental health. They are crucial for understanding the pathways to mental disorders as well as the interactions with biological parameters. However, deeper insight is needed into the complex interplay between the type of LE, its subjective evaluation and accompanying factors such as social support. The "Stralsund Life Event List" (SEL) was developed to facilitate this research. Methods: The SEL is a standardized interview that assesses
more » ... time of occurrence and frequency of 81 LEs, their subjective emotional valence, the perceived social support during the LE experience and the impact of past LEs on present life. Data from 2265 subjects from the general population-based cohort study "Study of Health in Pomerania" (SHIP) were analysed. Based on the mean emotional valence ratings of the whole sample, LEs were categorized as "positive" or "negative". For verification, the SEL was related to lifetime major depressive disorder (MDD; Munich Composite International Diagnostic Interview), childhood trauma (Childhood Trauma Questionnaire), resilience (Resilience Scale) and subjective health (SF-12 Health Survey). Results: The report of lifetime MDD was associated with more negative emotional valence ratings of negative LEs (OR = 2.96, p < 0.0001). Negative LEs (b = 0.071, p < 0.0001, β = 0.25) and more negative emotional valence ratings of positive LEs (b = 3.74, p < 0.0001, β = 0.11) were positively associated with childhood trauma. In contrast, more positive emotional valence ratings of positive LEs were associated with higher resilience (b = − 7.05, p < 0.0001, β = 0.13), and a lower present impact of past negative LEs was associated with better subjective health (b = 2.79, p = 0.001, β = 0.05). The internal consistency of the generated scores varied considerably, but the mean value was acceptable (averaged Cronbach's alpha > 0.75). Conclusions: The SEL is a valid instrument that enables the analysis of the number and frequency of LEs, their emotional valence, perceived social support and current impact on life on a global score and on an individual item level. Thus, we can recommend its use in research settings that require the assessment and analysis of the relationship between the occurrence and subjective evaluation of LEs as well as the complex balance between distressing and stabilizing life experiences.
doi:10.1186/s12888-018-1649-3 pmid:29669535 pmcid:PMC5907180 fatcat:nzazmaqqxjdexmwrm2w2qkkway

Moderation of adult depression by the serotonin transporter promoter variant (5-HTTLPR), childhood abuse and adult traumatic events in a general population sample

Hans Jörgen Grabe, Christian Schwahn, Jessie Mahler, Andrea Schulz, Carsten Spitzer, Kristin Fenske, Katja Appel, Sven Barnow, Matthias Nauck, Georg Schomerus, Reiner Biffar, Dieter Rosskopf (+3 others)
2012 American Journal of Medical Genetics Part B: Neuropsychiatric Genetics  
The impact of the promoter polymorphisms of the serotonin transporter (5-HTTLPR) on mood has been studied by two-way interaction models comprising one environmental factor and genotype variants. However, childhood abuse is assumed to be associated with different psychobiological long-term effects than adult traumatic events. Both types of trauma may interact on an individual basis throughout the lifespan moderating the impact of the 5-HTTLPR s allele on depressive disorders. Therefore, the
more » ... hesis of a three-way interaction among the 5-HTTLPR, childhood abuse and adult traumatic experience was tested. Caucasian subjects (1,974) from the general population in Germany (Study of Health in Pomerania (SHIP)) were analyzed. Depressive symptoms were measured with the Beck Depression Inventory (BDI-II). Childhood abuse was assessed with the Childhood Trauma Questionnaire. Adult traumatic events were derived from the SCID interview (DSM-IV) on posttraumatic stress disorder (PTSD). Global three-way interactions among the 5-HTTLPR, adult traumatic experiences and childhood abuse (P ¼ 0.0007) were found. Carriers of the ss or sl genotypes who had been exposed to childhood abuse and to more than two adult traumatic events had higher mean BDI-II scores ]) compared to those carrying the ll genotype (7.6 [4.5-10.7]). These results were supported using a second, more severe definition of childhood abuse (P ¼ 0.02). No two-way interactions were observed (P > 0.05). Childhood abuse and adult traumatic events may act synergistically in interaction with the s allele of the 5-HTTLPR to increase the risk for depressive symptoms independently from the lifetime diagnosis of PTSD.
doi:10.1002/ajmg.b.32027 pmid:22328412 fatcat:mlcxukgyrbe6lnalt27stjexti

Titelseiten / Inhalt / Autorenverzeichnis / Vorwort [chapter]

2002 Kompendium Psychiatrie, Psychotherapie, Psychosomatische Medizin  
Therapieverfahren in der Psychiatrie, Psychotherapie und Psychosomatik: Überblick Harald J. Freyberger, Rolf-Dieter Stieglitz, Wolfgang Schneider . . . . . . . . . . . . .  ...  VI Inhalt 13 Psychosomatische Störungen Harald J.  ...  Auflage verfasste «Kompendium der Psychiatrie und Psychotherapie», das von Harald Feldmann unter Mitwirkung von Johannes Brand-Jacobi und Mario Gmür 1983 revidiert wurde, wurde 1996 in 10.  ... 
doi:10.1159/000062868 fatcat:a5gvpspjgvczjojl4sefo6uo6e

Nachruf auf Prof. Dr. Harald J. Freyberger

Hans J. Grabe, Wolfgang Maier
2019 Nervenarzt  
Harald Jürgen Freyberger wurde nur 61 Jahre alt. Der plötzliche Tod kam für uns alle unerwartet und riss ihn am 06.12.2018 mitten aus dem Leben.  ...  Freyberger von 1980 bis 1986 Medizin am  ... 
doi:10.1007/s00115-019-0689-3 fatcat:gwk437qokrchxbyjryz3eslh24

Aktualität der Indikationsfrage

Wolfgang Schneider, Thomas Klauer
2016 Psychotherapeut (Berlin)  
Harald J.  ...  Die Arbeit von Jürgen Brunner gibt einen umfassenden Überblick über metaanalytische Befunde zur Wirksamkeit von Psychotherapie, Pharmakotherapie und Kombinationstherapie psychischer Störungen und die Ableitung  ... 
doi:10.1007/s00278-016-0117-0 fatcat:yw4hbyixirhudo3fypzorrmppm

Bibliographie [chapter]

2021 Das spätantike Rom und die stadtrömische Senatsaristokratie (395–455 n. Chr.)  
FREYBERGER (2013): Klaus S.  ...  FREYBERGER (2016): Klaus S. Freyberger,Die Basilica Aemilia auf dem Forum Romanum in Rom.  ... 
doi:10.1515/9783110727630-011 fatcat:64ze377s6fbr7akgzqd6gyxzim

"Who watches the watchers?"

Andreas Hamburger, Heidi Möller
2018 Organisationsberatung Supervision Coaching  
Harald Freyberger gibt einen Überblick über Qualifikationsanforderungen und Schulungsansätze für Ausbildungssupervisoren im Bereich der Psychotherapie.  ...  In unserer Rubrik "Diskurs" finden Sie eine Replik von Jürgen Kriz auf den Beitrag von Claus Nowak "Systemisch -was denn sonst!" im Heft 4/17: Nicht alles ist "systemisch".  ... 
doi:10.1007/s11613-018-0569-x fatcat:r7gylqa5efhslk6orfnh2n2ldm

Soziologische Phantasielosigkeit und verdinglichtes Lernen

Karl Lauschke
1977 Prokla  
Thomas von Freyberg u.a., a.a.O., S. 149 f.  ...  Protokoll Nr. 7 a, in: Thomas von Freyberg u. a., a.a,O., S. 223 ff.  ... 
doi:10.32387/prokla.v7i28.1687 fatcat:xwojys4k35fb3f25f4fwlc3vbm

Programmheft der DHd 2020 "Spielräume: Digital Humanities zwischen Modellierung und Interpretation" [article]

Benjamin Bellgrau
2020 Zenodo  
Phänomen Ulrike Wuttke Partizipatives Design in Digital Humanities Projekten: Checklist, Maßnahmenkatalog und Use-Case Swantje Dogunke Public Humanities Tools: Der Bedarf an niederschwelligen Services Jürgen  ...  Datenvisualisierungen Viktoria Brüggemann, Mark-Jan Bludau, Marian Dörk Ikonizität als Erkenntnismittel - Vollständigkeit, Verständlichkeit und Kontextualisierung als Grundprinzipien der Visualisierung Linda Freyberg  ... 
doi:10.5281/zenodo.3675424 fatcat:mozbdqvj2vakfegmeri7bn2xkq

Inhaltsverzeichnis [chapter]

Das Entgegenkommende Denken  
Between Dewey and Langer 39 Sascha Freyberg Ereignis und Objekt. Zur Whitehead-Kritik von Edgar Wind und John Dewey II.  ...  135 Jürgen Trabant Herders Schaaf im Vorbeigehen und Entgegenkommen V. Bewegung -Geste -Zeichen 147 Ulrich Mosch Übergänge.  ... 
doi:10.1515/9783110430899-toc fatcat:s2etxft3nvhn3ergtnv4owge34

Titelei/Inhaltsverzeichnis [chapter]

Michael Behr, Jochen Fanghänel, Matthias Hautmann, Peter Proff, Torsten E. Reichert
2020 Medizin für Zahnmediziner  
Harald-Jürgen Freyberger † Klinik für Psychiatrie und Psychotherapie der Universitätsmedizin Greifswald am HELIOS Hanseklinikum Stralsund Hanseklinikum Stralsund Rostocker Chaussee 70 18437 Stralsund Prof  ... 
doi:10.47420/9783769136128-i fatcat:hf672fguxzbk5acis4dojhz2je
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