Filters








27,038 Hits in 3.0 sec

Complement Objective Training [article]

Hao-Yun Chen, Pei-Hsin Wang, Chun-Hao Liu, Shih-Chieh Chang, Jia-Yu Pan, Yu-Ting Chen, Wei Wei, Da-Cheng Juan
<span title="2019-03-21">2019</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Learning with a primary objective, such as softmax cross entropy for classification and sequence generation, has been the norm for training deep neural networks for years. Although being a widely-adopted approach, using cross entropy as the primary objective exploits mostly the information from the ground-truth class for maximizing data likelihood, and largely ignores information from the complement (incorrect) classes. We argue that, in addition to the primary objective, training also using a
more &raquo; ... omplement objective that leverages information from the complement classes can be effective in improving model performance. This motivates us to study a new training paradigm that maximizes the likelihood of the groundtruth class while neutralizing the probabilities of the complement classes. We conduct extensive experiments on multiple tasks ranging from computer vision to natural language understanding. The experimental results confirm that, compared to the conventional training with just one primary objective, training also with the complement objective further improves the performance of the state-of-the-art models across all tasks. In addition to the accuracy improvement, we also show that models trained with both primary and complement objectives are more robust to single-step adversarial attacks.
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1903.01182v2">arXiv:1903.01182v2</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/5vh2g3bt4zgwpfgwwd2jvrctmy">fatcat:5vh2g3bt4zgwpfgwwd2jvrctmy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200828101950/https://arxiv.org/pdf/1903.01182v2.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c6/59/c659a916b515fd01b20e26e86a4422d5f2882e00.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1903.01182v2" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

Zinc oxide nanoparticles impair bacterial clearance by macrophages

Chia-Der Lin, Yu-Yi Kou, Chin-Yu Liao, Ching-Hao Li, Shiao-Ping Huang, Yu-Wen Cheng, Wei-Chih Liao, Hao-Xiang Chen, Pei-Ling Wu, Jaw-Jou Kang, Chen-Chen Lee, Chih-Ho Lai
<span title="">2014</span> <i title="Future Medicine Ltd"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ji3wac46u5gylarhb5okyfjem4" style="color: black;">Nanomedicine</a> </i> &nbsp;
Confocal microscopy was performed through the use of the microscopic facility at the Scientific Instrument Center of Academia Sinica and with the assistance of Shu-Chen Shen.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2217/nnm.14.48">doi:10.2217/nnm.14.48</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24628689">pmid:24628689</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/l2fn6krsgvhvtncjvbtyuiadca">fatcat:l2fn6krsgvhvtncjvbtyuiadca</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190301220247/http://pdfs.semanticscholar.org/aabe/7d98725970c49f23d7ff693755da8e60c30c.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/aa/be/aabe7d98725970c49f23d7ff693755da8e60c30c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2217/nnm.14.48"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Learning with Hierarchical Complement Objective [article]

Hao-Yun Chen, Li-Huang Tsai, Shih-Chieh Chang, Jia-Yu Pan, Yu-Ting Chen, Wei Wei, Da-Cheng Juan
<span title="2019-11-17">2019</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Label hierarchies widely exist in many vision-related problems, ranging from explicit label hierarchies existed in image classification to latent label hierarchies existed in semantic segmentation. Nevertheless, state-of-the-art methods often deploy cross-entropy loss that implicitly assumes class labels to be exclusive and thus independence from each other. Motivated by the fact that classes from the same parental category usually share certain similarity, we design a new training diagram
more &raquo; ... d Hierarchical Complement Objective Training (HCOT) that leverages the information from label hierarchy. HCOT maximizes the probability of the ground truth class, and at the same time, neutralizes the probabilities of rest of the classes in a hierarchical fashion, making the model take advantage of the label hierarchy explicitly. The proposed HCOT is evaluated on both image classification and semantic segmentation tasks. Experimental results confirm that HCOT outperforms state-of-the-art models in CIFAR-100, ImageNet-2012, and PASCAL-Context. The study further demonstrates that HCOT can be applied on tasks with latent label hierarchies, which is a common characteristic in many machine learning tasks.
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1911.07257v1">arXiv:1911.07257v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/slb5yavfpbeihnuwxxb6rg2ybq">fatcat:slb5yavfpbeihnuwxxb6rg2ybq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200928213333/https://arxiv.org/pdf/1911.07257v1.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/9e/72/9e7205968d0c166249ca64bfd4869f5ef8a05ce0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1911.07257v1" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

Successful resuscitation of out of hospital cardiac arrest patients in the emergency department

Shou-Yen Chen, Shih-Hao Wang, Yi-Ming Weng, Yu-Che Chang, Yu-Jr Lin, Ko-Chen Chang, Jiun-Hao Yu
<span title="2011-05-01">2011</span> <i title="Pharmamed Mado Ltd"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/vrckzcos2vdtllicur45dcedy4" style="color: black;">Signa Vitae</a> </i> &nbsp;
Background. We examined factors associated with the successful resuscitation, in the emergency department (ED), of adult, out-of-hospital cardiac arrest (OHCA) patients. Methods. The study cohort consisted of adult patients (over 18 years of age) who presented to the ED in 2009 with a diagnosis of cardiac arrest. Data were retrieved from the institutional database. Results. A total of 122 adult, non-traumatic, OHCA patients were enrolled in the study. There were no significant differences
more &raquo; ... n the sustained return of spontaneous circulation (ROSC) and non-sustained ROSC groups in initial body temperature (P = 0.420), time to successful intubation (P = 0.524), time to first intravenous epinephrine injection (P = 0.108), blood sugar levels (P = 0.122), hematocrit (P = 0.977), cardiac enzymes (P = 0.116) and serum sodium level (P = 0.429). Leukocytosis (P = 0.047) and cardiac rhythm of pulseless ventricular tachycardia/ ventricular fibrillation and pulseless electrical activity (P = 0.022), were significantly associated with sustained ROSC. In contrast, patients with more severe acidosis (P = 0.003) and hyperkalemia (P < 0.001) had a reduced likelihood of achieving sustained ROSC. After multiple variable logistic regression analysis adjusting for variables, the correlation between sustained ROSC and leukocytosis and hyperkalemia remained high (leukocytosis, P = 0.007, odds ratio [OR] 3.655, hyperkalemia, P = 0.001, OR 0.169, Conclusion. Patients suffering an OHCA were appropriately resuscitated after arriving at the ED. Successful resuscitation in adult OHCA victims was determined by the patient's status, in particular their white blood cell count and potassium level.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.22514/sv61.052011.3">doi:10.22514/sv61.052011.3</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/f73vz5k4gbfqlkw3nndezwowse">fatcat:f73vz5k4gbfqlkw3nndezwowse</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170706030659/http://hrcak.srce.hr/file/100797/" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/34/6d/346d7d9ceae1abcbcbb6a1fdf342179a3f1034d8.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.22514/sv61.052011.3"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Homoepitaxy of rhombohedral-stacked MoS2 with room temperature switchable ferroelectricity [article]

Tilo H. Yang, Hsiang-Chi Hu, Fu-Xiang Rikudo Chen, Po-Yen Lin, Yu-Fan Chiang, Wen-Hao Chang, Yi-Hao Kuo, Yu-Seng Ku, Bor-Wei Liang, Alice Chinghsuan Chang, Han-Chieh Lo, Yu-Chen Chang (+4 others)
<span title="2022-05-24">2022</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
The discovery of interfacial ferroelectricity in two-dimensional rhombohedral (3R)-stacked semiconductors opens up a new pathway for achieving ultrathin computing-in-memory devices. However, exploring ferroelectricity switching in natural 3R crystals is difficult due to lack of co-existing 3R stacking domains. Here, we present that MoS2 homoepitaxial patterns with 3R polytypic domains can manifest switchable ferroelectricity at room-temperature. Based on the diffusion limited aggregation
more &raquo; ... such MoS2 patterns are formed under the low Mo chemical potential and low temperature with respect to common chemical vapor deposition synthesis. The alternation of 3R polytypes in the MoS2 homoepitaxial patterns, observed by scanning transmission electron microscopy, accounts for ferroelectricity switching. The MoS2 field-effect transistors with 3R polytypic domains exhibit a repeatable counterclockwise hysteresis with gate voltage sweeping, an indication of ferroelectricity switching, and the memory window exceeds those measured for compact-shaped 3R bilayer devices. This work provides a direct growth concept for layered 3R-based ferroelectric memory.
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/2205.12118v1">arXiv:2205.12118v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ljpa5yszwrdjveb6rc6z2mm2lm">fatcat:ljpa5yszwrdjveb6rc6z2mm2lm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220526105935/https://arxiv.org/ftp/arxiv/papers/2205/2205.12118.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/e1/e0/e1e05e2857225fc9f9f7f55d237f1efe6acfc4c4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/2205.12118v1" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

Anatomy of Type-X Spin-Orbit Torque Switching [article]

Yan-Ting Liu, Chao-Chung Huang, Kuan-Hao Chen, Yu-Hao Huang, Chia-Chin Tsai, Ting-Yu Chang, Chi-Feng Pai
<span title="2021-08-03">2021</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Using type-x spin-orbit torque (SOT) switching scheme, in which the easy axis (EA) of the ferromagnetic (FM) layer and the charge current flow direction are collinear, is possible to realize a lower-power-consumption, higher-density, and better-performance SOT magnetoresistive random access memory (SOT-MRAM) as compared to the conventional type-y design. Here, we systematically investigate type-x SOT switching properties by both macrospin and micromagnetic simulations. The out-of-plane external
more &raquo; ... field and anisotropy field dependence of the switching current density (J_sw) is first examined in the ideal type-x configuration. Next, we study the FM layer canting angle (ϕ_EA) dependence of J_sw through macrospin simulations and experiments, which show a transformation of switching dynamics from type-x to type-y with increasing ϕ_EA. By further integrating field-like torque (FLT) into the simulated system, we find that a positive FLT can assist type-x SOT switching while a negative one brings about complex dynamics. More crucially, with the existence of a sizable FLT, type-x switching mode results in a lower critical switching current than type-y at current pulse width less than 10 ns, indicating the advantage of employing type-x design for ultrafast switching using materials systems with FLT. Our work provides a thorough examination of type-x SOT scheme with various device/materials parameters, which can be informative for designing next-generation SOT-MRAM.
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/2108.01272v1">arXiv:2108.01272v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/aopmazvwhvgvvdd7b47rbxls2m">fatcat:aopmazvwhvgvvdd7b47rbxls2m</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210804023851/https://arxiv.org/ftp/arxiv/papers/2108/2108.01272.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/85/a6/85a6af6069895213032716dbbf5b37314e2f6bba.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/2108.01272v1" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

HiPRIME:

Yahong Cao, Yu-Min Lee, Tsung-Hao Chen, Charlie Chung-Ping Chen
<span title="">2002</span> <i title="ACM Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/bonikunskbdgjicnz3tvcz7334" style="color: black;">Proceedings - Design Automation Conference</a> </i> &nbsp;
This paper proposes a general hierarchical analysis methodology, HiPRIME, to efficiently analyze RLKC power delivery systems. After partitioning the circuits into blocks, we develop and apply the IEKS (Improved Extended Krylov Subspace) method to build the Multi-port Norton Equivalent circuits which transform all the internal sources to Norton current sources at ports. Since there is no active elements inside the Norton circuits, passive or realizable model order reduction techniques such as
more &raquo; ... MA can be applied. To further reduce the top-level hierarchy runtime, we develop a second-level model reduction algorithm and prove its passivity. Experimental results show 400-700X runtime improvement with less than 0.2% error.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1145/514016.514017">doi:10.1145/514016.514017</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/bbatsgub3jfg5luwkj6h67uqgy">fatcat:bbatsgub3jfg5luwkj6h67uqgy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170808173014/http://vlsi-eda.cm.nctu.edu.tw/publish/conferences/2002dac1.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/40/06/4006288df37a25b5f2a3ea813af5cc4023252b91.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1145/514016.514017"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> acm.org </button> </a>

Janus Poly(Vinylidene Fluoride) Membranes with Penetrative Pores for Photothermal Desalination

Hao-Hao Yu, Lin-Jiong Yan, Ye-Cheng Shen, Si-Yu Chen, Hao-Nan Li, Jing Yang, Zhi-Kang Xu
<span title="2020-03-03">2020</span> <i title="American Association for the Advancement of Science (AAAS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4mtt3mthsrd5nfae4lpzcxekqu" style="color: black;">Research</a> </i> &nbsp;
Solar-driven desalination has been considered as a promising technology for producing clean water through an abundant and pollution-free energy source. It is a critical challenge to reasonably design the porous morphology and the thermal management of photothermal membranes for enabling efficient energy conversion and water production. In this work, a Janus poly(vinylidene fluoride) membrane was fabricated in combination of penetrative pore structure, asymmetric surface wettability with proper
more &raquo; ... hermal management for high-efficiency solar desalination. Highly open and directly penetrative pores achieved by the two-dimensional solvent freezing strategy are considered to provide direct pathways for water and vapor transportation. The unique feature of hydrophobic upper layer/hydrophilic lower layer enables the photothermal membranes to self-float on the water surface and rapidly pump water from the bulk to the surface. The resulting Janus membrane exhibits a satisfactory light absorbance as high as 97% and a photothermal conversion efficiency of 62.8% under one-sun irradiation in a direct contact mode. The solar-to-vapor efficiency rises up to 90.2% with the assistance of a thermal insulator adopted beneath. Both the Janus membrane and the composite setup are able to work efficiently with a high stability in seawater desalination, and the concentration of ion in condensed water is reduced to below 1 ppm. Therefore, Janus membranes with directly penetrative pores and photothermal surfaces shine a light on the development of high-performance solar evaporators for the practical application in solar seawater desalination.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.34133/2020/3241758">doi:10.34133/2020/3241758</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32206759">pmid:32206759</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7072121/">pmcid:PMC7072121</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/2cl4arpbqrdo7kagtgsfo6luse">fatcat:2cl4arpbqrdo7kagtgsfo6luse</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200307113321/http://downloads.spj.sciencemag.org/research/2020/3241758.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b5/5b/b55b61c0281587b0b6500c757abd5f0233492efb.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.34133/2020/3241758"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072121" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Electrothermal Desiccant Regeneration Technique for Air Dehumidification

Chih-Hao Chen, Yu-Hao Kang, Jing-Hung Lu, Ming-Lang Hung, Jyi-Ching Perng, Jiun-Jen Chen
<span title="2021-06-22">2021</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/vt2hc3xcijfofb7cwnxv4hhszi" style="color: black;">Processes</a> </i> &nbsp;
Adsorption dehumidification and drying equipment is essential general equipment for domestic and industrial use. The most commonly used type in industry is the compressed air adsorption dryer. The analysis results show that the heat loss of the traditional heat air regeneration system of the compressor dryer is 39.4%, and the exhaust waste heat is 32.4%. The actual use of heat energy for desiccant regeneration is only 28.2%. Therefore, this study uses an innovative electrothermal adsorbent unit
more &raquo; ... (ETAU) to regenerate the desiccant. By directly heating the adsorbent, heat loss can be effectively improved. On the other hand, the composite arrangement of zeolite and activated alumina is used. The inlet compressed air is firstly treated by the activated alumina, which has a high adsorption capacity in the high relative humidity condition, then a zeolite is used as a second part to make the dew point reach –40 °C. In the regeneration step, the airflow direction is reversed, whereby the zeolite is regenerated by the ETAU, and the waste heat of the exhaust air is used to regenerate the activated alumina, which reduces the temperature of the exhaust air. Compared with the traditional heat air compressed air system, the two technologies can save about 27% energy in total.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/pr9071082">doi:10.3390/pr9071082</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/3nqn4f7crjfsvigzjdak2idvlq">fatcat:3nqn4f7crjfsvigzjdak2idvlq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210629125918/https://res.mdpi.com/d_attachment/processes/processes-09-01082/article_deploy/processes-09-01082.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d3/ea/d3eac09fe9cd4fc8e3dbc8ad2a058630e436c992.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/pr9071082"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a>

Enabling nutrition-aware cooking in a smart kitchen

Pei-yu Chi, Jen-hao Chen, Hao-hua Chu, Bing-Yu Chen
<span title="">2007</span> <i title="ACM Press"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4obeqfuqs5gzbos5ah64a7m57a" style="color: black;">CHI &#39;07 extended abstracts on Human factors in computing systems - CHI &#39;07</a> </i> &nbsp;
We present a smart kitchen that can enhance the traditional meal preparation and cooking process by raising awareness of the nutrition facts in food ingredients that go into a meal. The goal is to promote healthy cooking. Our smart kitchen is augmented with sensors to detect cooking activities and provides digital feedbacks to users about nutritional information on the used food ingredients. We have created a preliminary prototype for evaluation, and the result is promising.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1145/1240866.1241003">doi:10.1145/1240866.1241003</a> <a target="_blank" rel="external noopener" href="https://dblp.org/rec/conf/chi/ChiCCC07.html">dblp:conf/chi/ChiCCC07</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/siub356jwna4pp3s67dptkalum">fatcat:siub356jwna4pp3s67dptkalum</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20070824091205/http://graphics.im.ntu.edu.tw/~robin/docs/wip07.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/e0/d1/e0d1a497d88f0387ba08818b6430e1f3694bde79.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1145/1240866.1241003"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> acm.org </button> </a>

A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke

Cong Wang, Hao Chen, Shi-tang Ma, Bin-bin Mao, Yu Chen, Hao-Nan Xu, Hao Yu, Francesca Mancianti
<span title="2021-08-13">2021</span> <i title="Hindawi Limited"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zncaxvmd7zbqjjpq55yaq6a3ay" style="color: black;">Evidence-Based Complementary and Alternative Medicine</a> </i> &nbsp;
Background. Panax notoginseng saponins (PNS) have been deemed effective herb compounds for treating ischaemic stroke (IS) and improving the quality of life of IS patients. This study aimed to investigate the underlying mechanisms of PNS in the treatment of IS based on network pharmacology. Methods. PNS were identified from the Traditional Chinese Medicine System Pharmacology (TCMSP) database, and their possible targets were predicted using the PharmMapper database. IS-related targets were
more &raquo; ... fied from the GeneCards database, OMIM database, and DisGeNET database. A herb-compound-target-disease network was constructed using Cytoscape, and protein-protein interaction (PPI) networks were established with STRING. GO enrichment and KEGG pathway analysis were performed using DAVID. The binding of the compounds and key targets was validated by molecular docking studies using AutoDock Vina. The neuroprotective effect of TFCJ was substantiated in terms of oxidative stress (superoxide dismutase, glutathione peroxidase, catalase, and malondialdehyde) and the levels of IGF1/PI3K/Akt pathway proteins. Results. A total of 375 PNS targets and 5111 IS-related targets were identified. Among these targets, 241 were common to PNS, and IS network analysis showed that MAPK1, AKT1, PIK3R1, SRC, MAPK8, EGFR, IGF1, HRAS, RHOA, and HSP90AA1 are key targets of PNS against IS. Furthermore, GO and KEGG enrichment analysis indicated that PNS probably exert therapeutic effects against IS by regulating many pathways, such as the Ras, oestrogen, FoxO, prolactin, Rap1, PI3K-Akt, insulin, PPAR, and thyroid hormone signalling pathways. Molecular docking studies further corroborated the experimental results.The network pharmacology results were further verified by molecular docking and in vivo experiments. Conclusions. The ameliorative effects of PNS against IS were predicted to be associated with the regulation of the IGF1-PI3K-Akt signalling pathway. Ginsenoside Re and ginsenoside Rb1 may play an important role in the treatment of IS.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1155/2021/5582782">doi:10.1155/2021/5582782</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34434246">pmid:34434246</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8382556/">pmcid:PMC8382556</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/umdkvekynjhi3m42y6jlwkljgm">fatcat:umdkvekynjhi3m42y6jlwkljgm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210819132603/https://downloads.hindawi.com/journals/ecam/2021/5582782.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ab/06/ab06b05ac01b2dcade5b3972cf651d6b9c12cb94.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1155/2021/5582782"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> hindawi.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382556" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

A gate-free monolayer WSe2 pn diode

Jhih-Wei Chen, Shun-Tsung Lo, Sheng-Chin Ho, Sheng-Shong Wong, Thi-Hai-Yen Vu, Xin-Quan Zhang, Yi-De Liu, Yu-You Chiou, Yu-Xun Chen, Jan-Chi Yang, Yi-Chun Chen, Ying-Hao Chu (+5 others)
<span title="2018-08-07">2018</span> <i title="Springer Nature America, Inc"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/a4wan6l5o5dfzn767kyz7jqevi" style="color: black;">Nature Communications</a> </i> &nbsp;
Interest in bringing p-and n-type monolayer semiconducting transition metal dichalcogenides (TMD) into contact to form rectifying pn diode has thrived since it is crucial to control the electrical properties in two-dimensional (2D) electronic and optoelectronic devices. Usually this involves vertically stacking different TMDs with pn heterojunction or, laterally manipulating carrier density by gate biasing. Here, by utilizing a locally reversed ferroelectric polarization, we laterally
more &raquo; ... the carrier density and created a WSe 2 pn homojunction on the supporting ferroelectric BiFeO 3 substrate. This non-volatile WSe 2 pn homojunction is demonstrated with optical and scanning probe methods and scanning photoelectron microspectroscopy. A homo-interface is a direct manifestation of our WSe 2 pn diode, which can be quantitatively understood as a clear rectifying behavior. The non-volatile confinement of carriers and associated gate-free pn homojunction can be an addition to the 2D electron-photon toolbox and pave the way to develop laterally 2D electronics and photonics.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41467-018-05326-x">doi:10.1038/s41467-018-05326-x</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30087328">pmid:30087328</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6081376/">pmcid:PMC6081376</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xidpc5l4sjbs3jzgqp5ae25sle">fatcat:xidpc5l4sjbs3jzgqp5ae25sle</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191109090647/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6081376&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/92/14/9214a451b3dd34b056e4f894d8f34c578fd64fa4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41467-018-05326-x"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> nature.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081376" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Toll‑like receptor 4 activates the NLRP3 inflammasome pathway and periodontal inflammaging by inhibiting Bmi‑1 expression

Zi‑Yue Qin, Xin Gu, Yu‑Lian Chen, Jia‑Bao Liu, Chen‑Xing Hou, Shi‑Yu Lin, Nan‑Nan Hao, Yan Liang, Wu Chen, Hao‑Yu Meng
<span title="2020-11-11">2020</span> <i title="Spandidos Publications"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/d4e4mldoirchvo3dcxz4fwrzgi" style="color: black;">International Journal of Molecular Medicine</a> </i> &nbsp;
Overproduction of pro‑inflammatory cytokines in the aged, which is called inflammaging, leads to the deterioration of periodontitis. Toll‑like receptor 4 (TLR4) plays a role in the regulation of cellular senescence, and its expression increases with age. However, there has been limited research into the molecular mechanisms underlying the onset of periodontal inflammaging, and the interplay between TLR4 and inflammaging. In the present study, wild‑type and TLR4 gene knockout mice were used to
more &raquo; ... vestigate the activation of the TLR4 pathway in mouse periodontitis and the expression of the nucleotide‑binding and oligomerization domain‑like receptor 3 (NLRP3) inflammasome, an upstream immune checkpoint during the development of inflammaging. Activation of TLR4 in a mouse model of periodontitis enhanced the expression of a senescence‑associated secretory phenotype (SASP), which boosted the inflammaging process. Conversely, TLR4 activation downregulated the expression of B cell‑specific Moloney murine leukemia virus integration site 1 (Bmi‑1) and promoted the priming of NLRP3 inflammasome, both of which are regulators of SASP. Treating gingival fibroblasts with Bmi‑1 inhibitor PTC209, it was demonstrated that TLR4 activated the NLRP3 pathway and the inflammaging process by suppressing Bmi‑1. In addition, there was a significant reduction in the expression of Bmi‑1 expression in the gingiva of patients with periodontitis compared with healthy controls. In conclusion, the present study demonstrated that TLR4 acted by inhibiting Bmi‑1 to enhance the NLRP3 pathway and SASP factors. This cascade of reactions may contribute to the senescence of the periodontium.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3892/ijmm.2020.4787">doi:10.3892/ijmm.2020.4787</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33236134">pmid:33236134</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7723510/">pmcid:PMC7723510</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/q7smbxaqgbgr3dasnezfgdobya">fatcat:q7smbxaqgbgr3dasnezfgdobya</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201214061450/https://www.spandidos-publications.com/10.3892/ijmm.2020.4787/download" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/07/00/0700c1361103e2dd1d4eebc52f19ab11968c11fd.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3892/ijmm.2020.4787"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723510" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

On the gaps between consecutive primes [article]

Yu-Chen Sun, Hao Pan
<span title="2018-02-07">2018</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Let p_n denote the n-th prime. For any m≥ 1, there exist infinitely many n such that p_n-p_n-m≤ C_m for some large constant C_m>0, and p_n+1-p_n≥c_m n n n/ n, for some small constant c_m>0. Furthermore, we also obtain a related result concerning the least primes in arithmetic progressions.
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1802.02470v1">arXiv:1802.02470v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/i63ywxrku5ddvfwfwopqwhslnq">fatcat:i63ywxrku5ddvfwfwopqwhslnq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201204175145/https://arxiv.org/pdf/1802.02470v1.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/93/a1/93a1e8b8e2f5b89858df243d44eaf8cf4dec4d53.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1802.02470v1" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

A q-analogue of Wilson's congruence [article]

Hao Pan, Yu-Chen Sun
<span title="2019-04-18">2019</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Let ${\mathcal C}_n$ be the set of all permutation cycles of length $n$ over $\{1,2,\ldots,n\}$. Let $${\mathfrak f}_n(q):=\sum_{\sigma\in{\mathcal C}_{n+1}}q^{{\mathrm maj}\,\sigma} $$ be a $q$-analogue of the factorial $n!$, where ${\mathrm maj}$ denotes the major index. We prove a $q$-analogue of Wilson's congruence $$ {\mathfrak f}_{n-1}(q)\equiv\mu(n)\pmod{\Phi_n(q)}, $$ where $\mu$ denotes the M\"obius function and $\Phi_n(q)$ is the $n$-th cyclotomic polynomial.
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1904.08857v1">arXiv:1904.08857v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ij5cmcbrhrftrper3rykvdih2y">fatcat:ij5cmcbrhrftrper3rykvdih2y</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200830074718/https://arxiv.org/pdf/1904.08857v1.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/77/eb/77ebdb78b1d4378456230aa4804e8d397f813471.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1904.08857v1" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>
&laquo; Previous Showing results 1 &mdash; 15 out of 27,038 results