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HFS: a performance-oriented flexible file system based on building-block compositions

Orran Krieger, Michael Stumm
1997 ACM Transactions on Computer Systems  
" ¥ ¢ ¡ @ D G b d D G # ¦ B P ¦ D 7 Q processes p1 p2 p7 file data file data processes p1 p2 p7 access pattern A access pattern B l ò ô l ¡ ¤ 0 P ¦ D H 7 1 E 1 5 D 5 § 3 §8 % H B 3 B 3 D G b 3 #  ...   à ŠAE Ç À ½ l È 2 Ç É 8 ¶ Q g 1 1 % ' Ê u b l B B % g Ë × Ø Ú Ù Î Ô Û i Ü B Ý ± Þ l Øß Ý Ò Ø Ô F Þ l Ö µ ' · l à d ¹ º $ » d ½ ¾ F ¿ l À Á i  à y Å AE w Ç À ½ n È 2 Ç °É 8 ¶ n á d G i B 1 % B l °Ë  ... 
doi:10.1145/263326.263356 fatcat:5wipz4seozdt5oqqnemrszo5mq

VPH-HF: A software framework for the execution of complex subject-specific physiology modelling workflows

Marco Viceconti, Simone Bnà, Daniele Tartarini, Stelios Sfakianakis, James Grogan, Dawn Walker, Samuel Gamble, Debora Testi
2018 Journal of Computational Science  
The aim of this paper is to present a new open source software, the VPH Hypermodelling Framework (VPH-HF).  ...  The VPH-HF also provide an automatic caching system over the execution of every hypomodel, which may provide considerable speed-up when the orchestration is run repeatedly over large numbers of patients  ...  The arrow symbol represents a link between the caller (arrow base block) and the called (arrow head block) in a service call.  ... 
doi:10.1016/j.jocs.2018.02.009 fatcat:pmf76efz6jczrpiasz5jaijasu

Stream-monitoring with blockmon

Davide Simoncelli, Maurizio Dusi, Francesco Gringoli, Saverio Niccolini
2013 Computer communication review  
We compare its performance against Storm and Apache S4, the state-ofthe-art open-source stream-processing platforms, by implementing a phone call anomaly detection system and a Twitter trending algorithm  ...  Recent work in network measurements focuses on scaling the performance of monitoring platforms to 10Gb/s and beyond.  ...  A distributed application requires users to implement a serialize method for exporting data from a block of a node, and a build same method for importing data on a block located on another node.  ... 
doi:10.1145/2479957.2479962 fatcat:w7ss2vzdwfccjldxriv42jwz4a

Systematic Dissection of Sequence Elements Controlling σ70 Promoters Using a Genomically-Encoded Multiplexed Reporter Assay in E. coli [article]

Guillaume Urtecho, Arielle D. Tripp, Kimberly Insigne, Hwangbeom Kim, Sriram Kosuri
2017 bioRxiv   pre-print
Here we develop a novel multiplexed assay to study promoter function in E. coli by building a site-specific genomic recombination-mediated cassette exchange (RMCE) system that allows for the facile construction  ...  We build and test a library of 10,860 σ70 promoter variants consisting of all combinations of a set of eight -35 elements, eight -10 elements, three UP elements, eight spacers, and eight backgrounds.  ...  based on sequence element composition.  ... 
doi:10.1101/207332 fatcat:eswcwsfmoje5zfcngsksh3dcby

Systematic Dissection of Sequence Elements Controlling σ70 Promoters Using a Genomically-Encoded Multiplexed Reporter Assay in E. coli

Guillaume Urtecho, Arielle D Tripp, Kimberly Insigne, Hwangbeom Kim, Sriram Kosuri
2018 Biochemistry  
Here we develop a novel multiplexed assay to study promoter function in E. coli by building a site-specific genomic recombination-mediated cassette exchange system that allows for the facile construction  ...  We build and test a library of 10898 σ70 promoter variants consisting of all combinations of a set of eight -35 elements, eight -10 elements, three UP elements, eight spacers, and eight backgrounds.  ...  based on sequence element composition.  ... 
doi:10.1021/acs.biochem.7b01069 pmid:29388765 pmcid:PMC6389444 fatcat:lj2aq47rkbegjjbzgcqjyh74t4

A Multi-sensor Traffic Scene Dataset with Omnidirectional Video

Philipp Koschorrek, Tommaso Piccini, Per Oberg, Michael Felsberg, Lars Nielsen, Rudolf Mester
2013 2013 IEEE Conference on Computer Vision and Pattern Recognition Workshops  
The dataset consists of sequences recorded in various environments from a car equipped with an omnidirectional multi-camera, height sensors, an IMU, a velocity sensor, and a GPS.  ...  This paper describes an experimental setup and software environment for recording such synchronized multi-sensor data streams and storing them in a new open source format.  ...  work has been funded by the Swedish Excellence Center at Linköping -Lund in Information Technology (ELLIIT) and the Linnaeus research environment for Control, Autonomy and Decision-making in Complex Systems  ... 
doi:10.1109/cvprw.2013.110 dblp:conf/cvpr/KoschorrekPOFNM13 fatcat:uczymofqvnadziq22xfw25hbum

Synthesis, biophysical properties, and RNase H activity of 6'-difluoro[4.3.0]bicyclo-DNA

Sibylle Frei, Adam K Katolik, Christian J Leumann
2019 Beilstein Journal of Organic Chemistry  
The difluorinated thymidine phosphoramidite building block was synthesized starting from an already known gem-difluorinated tricyclic glycal.  ...  Furthermore, since the structural investigation on the nucleoside level by X-ray crystallography and ab initio calculations pointed to a furanose conformation in the southern region, a RNase H cleavage  ...  However, based on previous observations in the nucleoside synthesis of the 6'F-bc 4,3 -T [37] we thought to construct the 6'-diF-bc 4,3 building block in utilizing this methodology.  ... 
doi:10.3762/bjoc.15.9 pmid:30680042 pmcid:PMC6334804 fatcat:r7rendqab5anjeelsgljhkk4hm

Factors Affecting the Synthesis of Autonomous Sensors with RFID Interface

Mariusz Węglarski, Piotr Jankowski-Mihułowicz
2019 Sensors  
A general view on the problem of designing atypical battery-free, autonomous semi-passive RFID transponders-sensors (autonomous sensors with RFID interfaces) is presented in this review.  ...  Moreover, a trial and error method is the most commonly used in the today's process of designing new solutions, and the basic parameters are estimated on the basis of the tests and the research team experience  ...  A similar procedure can be performed for UHF systems, based on the search for points at which minimum power P Tmin is supplied to tags.  ... 
doi:10.3390/s19204392 fatcat:xbn7wshhjrfcxgxkkv7lpgi6kq

Unified Graphical Co-modelling of Cyber-Physical Systems Using AADL and Simulink/Stateflow [chapter]

Haolan Zhan, Qianqian Lin, Shuling Wang, Jean-Pierre Talpin, Xiong Xu, Naijun Zhan
2019 Lecture Notes in Computer Science  
This paper focuses on the required concepts to combine them together, and outlines how to verify and simulate a system model defined using the combined graphical views of its constituents, by considering  ...  the case study of an Isollete System.  ...  Being based on a large palette of individually simple function blocks and their composition by continuous-time synchronous dataflow as well as the modelling capabilities of statecharts for reactive systems  ... 
doi:10.1007/978-3-030-31038-7_6 fatcat:niqmamhgarb65lh53m4pqr64gi

Discriminative Acoustic Event Recognition In Multimedia Recordings

Saurabh Khanwalkar, Premkumar Natarajan, Guruprasad Saikumar, Amit Srivastava
2011 Zenodo  
In [5] , they report on building a parallel classification system based on GMM for the discrimination of ambient noise, scream and gunfire sounds.  ...  vector blocks symmetrically on both sides.  ... 
doi:10.5281/zenodo.42495 fatcat:gdhsjkndjrg4zcgpztvpey45sm

FEMPAR: An Object-Oriented Parallel Finite Element Framework

Santiago Badia, Alberto F. Martín, Javier Principe
2017 Archives of Computational Methods in Engineering  
FEMPAR is an open source object oriented For-tran200X scientific software library for the high-performance scalable simulation of complex multiphysics problems governed by partial differential equations  ...  It is a highly modularized, flexible, and extensible library, that provides a set of modules that can be combined to carry out the different steps of the simulation pipeline.  ...  Based on our experience, the integration part of a FE code must exhibit a huge level of flexibility.  ... 
doi:10.1007/s11831-017-9244-1 pmid:29962831 pmcid:PMC6003441 fatcat:ighq7azdkvfsripfpsqvq5rwtm

Physical machine learning outperforms "human learning" in Quantum Chemistry [article]

Anton V. Sinitskiy, Vijay S. Pande
2020 arXiv   pre-print
Based on these equations, we build a deep neural network that can compute electron densities and energies of a wide range of organic molecules not only much faster, but also closer to exact physical values  ...  Thus, physics-based ML offers exciting opportunities for modeling, with high-theory-level quantum chemical accuracy, of much larger molecular systems than currently possible.  ...  Data availability The fchk files for all QM9 molecules computed with PBE0/pcS-3 and HF/pcS-3, as well as a file with the corresponding energies, are available from Stanford Digital Repository by the following  ... 
arXiv:1908.00971v2 fatcat:ks5gbxyzdrcpfbiqxmmbnbt4yq

Review—Heterogeneous 3D Graphene Derivatives for Supercapacitors

Sandhya Venkateshalu, Andrews Nirmala Grace
2020 Journal of the Electrochemical Society  
Graphene, a 2D structured material often suffers from agglomeration thereby limiting its performance.  ...  One such device is a supercapacitor, which has been gaining attention in the past decade with its excellent energy and power density.  ...  , making them an interesting filed of research. 65, 66 Large amount of literature could be found on various composites of graphene aerogel with metal oxides, polymers, dopants for supercapacitor application  ... 
doi:10.1149/1945-7111/ab6bc5 fatcat:qeuvoejgijab7ap2qacp5tndke

Structural basis for how sMAC is packaged for clearance [article]

Anais Menny, Marie V. Lukassen, Emma C. Couves, Vojtech Franc, Albert J.R. Heck, Doryen Bubeck
2021 bioRxiv   pre-print
However, how these chaperones block further polymerization of MAC and prevent the complex from binding target membranes remains unclear.  ...  Furthermore, we show that the pore-forming C9 protein is trapped in an intermediate conformation whereby only one of its two transmembrane β-hairpins has unfurled.  ...  One of the first lines of defence 37 against Gram-negative bacteria 1 , MAC is a potent weapon of the innate immune system 38 that can rupture lipid bilayers of any composition.  ... 
doi:10.1101/2021.04.06.438592 fatcat:cnoqwwldg5dc5o2ig46ufibbzq

Rapid parameterization of small molecules using the force field toolkit

Christopher G. Mayne, Jan Saam, Klaus Schulten, Emad Tajkhorshid, James C. Gumbart
2013 Journal of Computational Chemistry  
A variety of tools are provided to generate quantum mechanical target data, setup multidimensional optimization routines, and analyze parameter performance.  ...  Distributed as a VMD plugin, ffTK facilitates the traversal of a clear and organized workflow resulting in a complete set of CHARMMcompatible parameters.  ...  Biopolymers (e.g., proteins, DNA, and carbohydrates) lend themselves quite well to this concept due to their modular nature and composition from a relatively small set of independent building blocks (amino  ... 
doi:10.1002/jcc.23422 pmid:24000174 pmcid:PMC3874408 fatcat:2avdqkgsrzbitiszn73lgwt63e
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