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Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Psychiatric Disorders

Theodoros Bermperidis, Simon Schafer, Fred H. Gage, Terrence Sejnowski, Elizabeth B. Torres
2022 Frontiers in Neuroscience  
HEV genes have large hubs and a fragile topology, whereas LEV genes show more distributed code during the maturation toward neuronal state.  ...  The advent of open access to genomic data offers new opportunities to revisit old clinical debates while approaching them from a different angle.  ...  We next explore a full probabilistic graphical model and visualize the global behavior of these genes.  ... 
doi:10.3389/fnins.2022.884707 pmid:35720720 pmcid:PMC9201694 fatcat:qambex6lxrezfjjj7ujz2o7fxi

A Comprehensive Review on Classification, Energy Management Strategy, and Control Algorithm for Hybrid Electric Vehicles

Qicheng Xue, Xin Zhang, Teng Teng, Jibao Zhang, Zhiyuan Feng, Qinyang Lv
2020 Energies  
In this research, a comprehensive, multi-level classification for HEVs is introduced in detail from the aspects of the degree of hybridization (DoH), the position of the motor, the components and configurations  ...  Finally, some discussions about potential directions and challenges for future research on the energy management systems of HEVs are presented.  ...  the stage of scientific research.  ... 
doi:10.3390/en13205355 fatcat:pbc7o6bbebbwhmywojeyjkj7j4

High Efficiency Video Coding Compliant Perceptual Video Coding Using Entropy Based Visual Saliency Model

Muhammad Zeeshan, Muhammad Majid
2019 Entropy  
In the context of perceptual video coding (PVC), computational visual saliency models that utilize the charactertistics of the human visual system to improve the compression ratio are of paramount importance  ...  To date, only a few PVC schemes have been reported that use the visual saliency model.  ...  MS-SSIM takes into account the mechanism of processing in the early vision system and implements it on multiple scales.  ... 
doi:10.3390/e21100964 fatcat:ssh6qdzvqbglpmxwisumenj7t4

Practical Product Path Guiding Using Linearly Transformed Cosines

Stavros Diolatzis, Adrien Gruson, Wenzel Jakob, Derek Nowrouzezahrai, George Drettakis
2020 Computer graphics forum (Print)  
Despite the computational efficiency of LTCs, several optimizations are needed to make our method cost effective.  ...  Path guiding has recently emerged as a powerful strategy to counter the notoriously long computation times required to render such images.  ...  The authors are grateful to Inria Sophia Antipolis -Méditerranée "Nef" computation cluster (https://wiki.inria.fr/ClustersSophia/ Clusters_Home) and National Systems of Compute Canada for providing resources  ... 
doi:10.1111/cgf.14051 fatcat:3psao64qofesvjhlmnrymgma6i

Scanning the Issue

Azim Eskandarian
2022 IEEE transactions on intelligent transportation systems (Print)  
With the development of deep representation learning, the domain of reinforcement learning (RL) has become a powerful learning framework now capable of learning complex policies in high-dimensional environments  ...  This review summarizes deep reinforcement learning (DRL) algorithms and provides a taxonomy of automated driving tasks where (D)RL methods have been employed, while addressing key computational challenges  ...  The static model is fast to compute and gives a good estimation of the energy consumption for conventional railway systems.  ... 
doi:10.1109/tits.2022.3174254 fatcat:o6z3ncdkgbh5dmvvywtok7hwke

Deep Learning for fault diagnostics in Bearings, Insulators, PV panels, Power Lines and Electric Vehicle applications The State-of-the-Art Approaches

K Mohana Sundaram, Azham Hussain, P Sanjeevikumar, Jens Bo Holm-Nielsen, Vishnu Kumar Kaliappan, B Kavya Santhoshi
2021 IEEE Access  
This work puts forward the importance of DL and its application in a few critical electrical segments.  ...  A summary of different techniques used in DL is outlined, and finally, a review on the application of deep learning techniques in some popular electrical applications is presented.  ...  In DL, exploitation of multiple stages of processed non-linear information in a hierarchical pattern is done for feature learning and pattern classification.  ... 
doi:10.1109/access.2021.3064360 fatcat:cwdnnduwabbqpnxldzi2bdpxkm

Editorial

Srikanta Patnaik, Srikanta Patnaik
2018 Journal of Intelligent & Fuzzy Systems  
The next paper entitled "Early warning classification of cluster supply chain emergency based on cloud model and data stream clustering algorithm" by Xue Hong proposes a cloud model based algorithm for  ...  generating early warning indicators for cluster supply chain.  ... 
doi:10.3233/jifs-169562 fatcat:2qknpgafxjdaza2ppepzpwxreu

Toward Holistic Energy Management Strategies for Fuel Cell Hybrid Electric Vehicles in Heavy-Duty Applications

Thomas Rudolf, Tobias Schurmann, Stefan Schwab, Soren Hohmann
2021 Proceedings of the IEEE  
Das et al. [7] give a thorough survey of the FCHEV drivetrain, various energy storage systems (ESSs), and topologies for FCHEVs that are in the focus of the contribution.  ...  Finally, the findings lead to a guideline toward holistic EMSs, encouraging the co-optimization of system design, and EMS development for FCHEVs.  ...  For the development of a holistic EMS, a hierarchical MPC approach seems to be promising.  ... 
doi:10.1109/jproc.2021.3055136 fatcat:wtumpga3ifdwfiqou4gh2voaoq

Intravital Microscopy

Cenk Sumen, Thorsten R. Mempel, Irina B. Mazo, Ulrich H. von Andrian
2004 Immunity  
J. to Peyer's patch-HEV in situ: The multistep model confirmed and  ...  (Springer, 1994), in situ, there is now a plethora of IVM models and in vitro systems that could conceivably be useful to access vir-adhesive strength is also thought to play a role for stable synapse  ...  Acknowledgments photon tissue imaging: seeing the immune system in a fresh light. Nat. Rev. Immunol. 2, 872-880.  ... 
doi:10.1016/j.immuni.2004.08.006 pmid:15357943 fatcat:x267hv2renbirawm5jestx2lea

Intravital MicroscopyVisualizing Immunity in Context

C SUMEN, T MEMPEL, I MAZO, U VONANDRIAN
2004 Immunity  
J. to Peyer's patch-HEV in situ: The multistep model confirmed and  ...  (Springer, 1994), in situ, there is now a plethora of IVM models and in vitro systems that could conceivably be useful to access vir-adhesive strength is also thought to play a role for stable synapse  ...  Acknowledgments photon tissue imaging: seeing the immune system in a fresh light. Nat. Rev. Immunol. 2, 872-880.  ... 
doi:10.1016/s1074-7613(04)00237-7 pmid:15357943 fatcat:o4vzfkrtofeg5cm7coav6kcjq4

Toward a multiscale model of antigen presentation in immunity

Denise E. Kirschner, Stewart T. Chang, Thomas W. Riggs, Nicolas Perry, Jennifer J. Linderman
2007 Immunological Reviews  
Despite a wealth of information in the biological literature regarding each of these scales, no single representation synthesizing this information into a model of the overall immune response as it depends  ...  The immune system and the process of antigen presentation in particular encompass events that occur at multiple length and time scales.  ...  The authors thank Simeone Marino and Seema Bajaria for use of results from their published work.  ... 
doi:10.1111/j.1600-065x.2007.00490.x pmid:17367337 fatcat:dy4xeaaxnzd4jejudvgqhdoqyy

Multifarious hierarchies of mechanical models for artist assigned levels-of-detail

Richard Malgat, Benjamin Gilles, David I. W. Levin, Matthieu Nesme, François Faure
2015 Proceedings of the 14th ACM SIGGRAPH / Eurographics Symposium on Computer Animation - SCA '15  
The models are ordered to apply their deformations hierarchically, and we enforce the uniqueness of the dynamics solutions using a novel kinetic filtering operator designed to ensure that each child only  ...  Abstract We present a new framework for artist driven level of detail in solid simulations.  ...  Acknowledgments The authors wish to thank Laura Paiardini for her help with the models, textures, renderings and video editing and Romain Testylier for his help with the rod simulation.  ... 
doi:10.1145/2786784.2786800 dblp:conf/sca/MalgatGLNF15 fatcat:vcgw6tpfsvhvhlemiw3af3hce4

Scanning the Issue

Azim Eskandarian
2022 IEEE transactions on intelligent transportation systems (Print)  
This article investigates the influence of an external humanmachine interface (eHMI) for automated vehicles on pedestrian behavior in a parking lot.  ...  The efficiency and perceived safety of different signal types on the eHMI are analyzed by collecting data on the subjects' movement behavior and ratings via questionnaires.  ...  In this article, we design a visual analysis system for flight delay propagation.  ... 
doi:10.1109/tits.2022.3160062 fatcat:4gklzaonfzcehnvps6oge35fwe

Separable Roles for Attentional Control Sub-Systems in Reading Tasks: A Combined Behavioral and fMRI Study

S.K.Z. Ihnen, Steven E. Petersen, Bradley L. Schlaggar
2013 Cerebral Cortex  
First, RTevidence was found in support of the 2-mechanism model, corroborating the previous study.  ...  both behaviorally and neuroanatomically; and that the 2 mechanisms involve functionally separable control systems.  ...  We also thank David Balota and Rebecca Treiman for helpful discussions of the interpretation of the Behavioral study at early stages, and Jessica Church and Steve Nelson for careful reading and fruitful  ... 
doi:10.1093/cercor/bht313 pmid:24275830 pmcid:PMC4397571 fatcat:jhrvu3owhzerhkszvfjudocy3m

Network representations of immune system complexity

Naeha Subramanian, Parizad Torabi-Parizi, Rachel A. Gottschalk, Ronald N. Germain, Bhaskar Dutta
2015 Wiley Interdisciplinary Reviews: Systems Biology and Medicine  
The mammalian immune system is a dynamic multi-scale system composed of a hierarchically organized set of molecular, cellular and organismal networks that act in concert to promote effective host defense  ...  We illustrate the power of integrating 'omics' and network modeling approaches for unbiased reconstruction of signaling and transcriptional networks with a focus on applications involving the innate immune  ...  Acknowledgments This work was generously supported by the Intramural Research Program of the National Institute of Allergy and Infectious Diseases, and institutional support funds from the Institute for  ... 
doi:10.1002/wsbm.1288 pmid:25625853 pmcid:PMC4339634 fatcat:pe7eqjaqijhgrhhz5wtfep42ju
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