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Growth simulation of human embryo brain
Proceedings Spring Conference on Computer Graphics
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We employed this to create a growth simulation of the human embryo brain. The idea of this technique is the following. ...
The growth of the brain of human embryo is changing through a long time in the body of mother. So it is very difficult to observe and to understand that process. ...
Acknowledgements Authors wish to thank Mineo Yasuda from Medical School of Hiroshima University for sharing the knowledge as an embryologist. ...
doi:10.1109/sccg.2001.945348
fatcat:ls4w5j3hvvakfkf7ktmaqy4piq
Researches in National Institute of Radiological Sciences (NIRS) for radiation protection of non-human biota and ecosystems in Japanese environment
2009
Radioprotection - Revue de la Societé Francaise de Radioprotection
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Dose-effect relationships of acute gamma radiation on the survival, growth, and reproduction of selected organisms have been studied. ...
The microcosm has been simulated as a computer simulation code. Developments of more complicated and practical model ecosystems have been started. ...
The grown irradiated embryos, however, had smaller brains and eyes than the non-irradiated control embryos. ...
doi:10.1051/radiopro/20095103
fatcat:4x5tp3gycjd4zefq4tohmcp3ta
Mechanisms of Brain Morphogenesis
[chapter]
2013
Computer Models in Biomechanics
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Specifically, we focus on two processes: formation of the primary brain vesicles and folding of the cerebral cortex. ...
In this review we discuss recent advances in our understanding of the physical mechanisms of morphogenesis during brain development. ...
Acknowledgements We gratefully acknowledge funding support from NIH grants R01 GM075200 and R01 NS070918 (LAT), as well as a fellowship for BAF from NIH T90 DA022871 and the Mallinckrodt Institute of Radiology ...
doi:10.1007/978-94-007-5464-5_24
fatcat:5yweefpswrhjlieqltpinofs4q
Page 457 of JAMA Pediatrics Vol. 87, Issue 4
[page]
1954
JAMA Pediatrics
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Rat embryos exposed to radia- tion on the ninth day of gestation developed tumor-like growths in the brain, which microscopically consisted of closely packed masses of cells of the developing neu- ral ...
Enzyme inhibitors, especially those that simulate radiation reactions by interfering with sulfhydryl enzymes, have been used to produce brain malforma- tions in rat and mice fetuses.®
Little attention ...
A potential role for differential contractility in early brain development and evolution
2012
Biomechanics and Modeling in Mechanobiology
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Differences in brain structure between species have long fascinated evolutionary biologists. Understanding how these differences arise requires knowing how they are generated in the embryo. ...
round cross sections of the tubular brain into shapes resembling triangles, diamonds, and narrow slits. ...
and Xenopus laevis embryos, respectively. ...
doi:10.1007/s10237-012-0389-4
pmid:22466353
pmcid:PMC3475747
fatcat:pdq7vmc3gjfjlfkvimxkkbx7me
Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
2022
Veterinary World
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This review aimed to highlight some of the most important similarities between zebrafish and humans by emphasizing the relevance of the first in simulating neurological disorders and craniofacial deformity ...
At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. ...
[94] have studied the impact of different metal alloy shells of Procelian fused metal alloy crowns on the growth of ZF embryos and larvae. ...
doi:10.14202/vetworld.2022.22-29
pmid:35369579
pmcid:PMC8924399
fatcat:jo6nwfyfwvbohekr4y4byt22ya
Page 624 of JAMA Pediatrics Vol. 89, Issue 5
[page]
1955
JAMA Pediatrics
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On about the ninth day, parts of the embryo develop radiosensitivity, and this change in suscepti- bility coincides with a new pattern of growth, namely, rapid differentiation and the appearance of neuroblasts ...
The quantitative sensitivity of the human
neuroblast is not known. , . Hopason, Rochester, Minn.
GRowTH, DIFFERENTIATION, AND DisEASE. Epwarp B. D. NeunAusER, Am. J. ...
Growth Pattern of 'Matrix Cells' of the Central Nervous System and Formation of Tubular Structure Simulating Neural Tube in Cultures of Human Fetal Brain
1961
Archivum histologicum japonicum
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In order to examine the mitotic behavior and growth pattern of these matrix cells in vitro, we cultured ventricular wall of diencephalon or mesencephalon of seven to eight week human embryos by usual roller ...
Fig. 1 . 1 Wall of neural tube of seven week human embryo. m indicates mitotic cell in metaphase (so-called germinal cell of HIS). ...
doi:10.1679/aohc1950.22.117
fatcat:kgkg3duxhfezbglzjre6mfl4em
Effects of hypergravity environments on amphibian development, gene expression and apoptosis
2006
Comparative Biochemistry and Physiology A
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Apoptosis in brain and eye inner structures of hatching embryos was scored using the TUNEL staining method, and gene expression in tail-bud embryos was analyzed by whole-mount in situ hybridization. ...
and eye development) and Xag1 (regulating cement gland formation). (3) Eggs and 2 cell stage embryos raised at 5G showed a greater extent of brain and eye apoptosis compared with controls, while those ...
and growth, including insulin-like growth factor-II (IGF-II), causing an increase in apoptosis, eventually resulting in loss of skeletal muscle mass and function. ...
doi:10.1016/j.cbpa.2006.05.006
pmid:16807024
fatcat:foo22twaindgvhjxjfmpwn5iqu
Morphological Study of The Effects of Caffeine Beverages can Cause Birth Defects on Swiss White Mice Embryos
2021
Scientific Journal for Faculty of Science-Sirte University
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Small embryos folded like a ball and curved in the shape of letter C, and the severity of the deformities increased by the appearance of mutated embryos resembling the body of a fish and deformed embryos ...
characterized by the appearance of elongated and enlarged embryos. ...
Acknowledgements This work was supported by the department of biology, college of education for pure sciences, Mosul university. ...
doi:10.37375/sjfssu.v1i1.65
fatcat:xtn5r2wuljffdbhoqiw26zystu
My Corporis Fabrica Embryo: An ontology-based 3D spatio-temporal modeling of human embryo development
2015
Journal of Biomedical Semantics
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interactive simulation and visualization of 3D embryos. ...
My Corporis Fabrica Embryo: An ontology-based 3D spatio-temporal modeling of human embryo development. ...
Computer modeling and simulation of human body allow to express and to visualize complex physiological processes, to make the steps of human embryology more accessible. ...
doi:10.1186/s13326-015-0034-0
pmid:26413258
pmcid:PMC4582726
fatcat:sgv4nxqd2vevncli5hdds6udbm
Identify a Blood-Brain Barrier Penetrating Drug-TNB using Zebrafish Orthotopic Glioblastoma Xenograft Model
2017
Scientific Reports
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However, GBM is characteristic of extremely aggressive growth and surgery is difficult to achieve complete resection of tumor tissue 2 . ...
We then transplanted human GBM tumor cells into the zebrafish brain, in which implanted GBM cells (U87 and U251) were highly mitotic and invasive, mimicking their malignancy features in rodents' brain. ...
This work was supported by grants from the National Science Funding of China (81500153; 81502522; 81402275), Postdoctoral Fellowship of China (58-2549) and CSCO-MERCK SERONO ONCLOGY RESEARCH FUND (Y-MX2015 ...
doi:10.1038/s41598-017-14766-2
pmid:29085081
pmcid:PMC5662771
fatcat:ah7douev7vdtfdnyxkc5iykqce
Formation of the circle of Willis during human embryonic development
2016
Congenital Anomalies
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We examined the timing of formation of CW in 20 Japanese human embryo samples by using 3-dimensional reconstruction of serial histological sections. ...
The circle of Willis (CW) is a circulatory anastomosis that supplies blood to the brain and adjacent structures. ...
Acknowledgements 10 This study was supported by Grant Nos. 25461642, 24119002, 26220004, 15H01119, 15K08134, 15H05270, 15H01121, and 15K15014 from the Japan Society for the Promotion of Science. ...
doi:10.1111/cga.12165
pmid:27037515
fatcat:ueshciw3yrhtzjxvz3bh5n5cxi
Computational models for mechanics of morphogenesis
2012
Birth Defects Research Part C Embryo Today Reviews
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Mechanics plays a key role in regulating and controlling morphogenesis, and quantitative models help us understand how various mechanical forces combine to shape the embryo. ...
In the developing embryo, tissues differentiate, deform, and move in an orchestrated manner to generate various biological shapes driven by the complex interplay between genetic, epigenetic, and environmental ...
Acknowledgments This work was supported by grants R01 GM075200 and R01 NS070918 (LAT), F32 GM093396 (MAW), and T90 DA022871 (BAF) from the National Institutes of Health, the American Academy of Mechanics ...
doi:10.1002/bdrc.21013
pmid:22692887
pmcid:PMC3374861
fatcat:5ki7bda4dfgeloyvgsvd3i3uxy
Zebrafish embryo as a tool to study tumor/endothelial cell cross-talk
2013
Biochimica et Biophysica Acta - Molecular Basis of Disease
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Tumor/endothelial cell cross-talk plays a pivotal role in the growth, neovascularization and metastatic dissemination of human cancer. ...
In particular, grafting of mammalian tumor cells in zebrafish embryo body may simulate early stages of tumor development, neovascularization, and local invasion whereas the injection of cancer cells in ...
The mechanism of local invasion of tumor cells was investigated further by Lal et al. [34] following the orthotopic injection of human glioblastoma cells into the brain of zebrafish embryos. ...
doi:10.1016/j.bbadis.2013.01.016
pmid:23357577
fatcat:id3qq3vbkva75faepnhdhbqyuy
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