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Growing Trees in Child Brains: Graph Theoretical Analysis of Electroencephalography-Derived Minimum Spanning Tree in 5- and 7-Year-Old Children Reflects Brain Maturation

Maria Boersma, Dirk J.A. Smit, Dorret I. Boomsma, Eco J.C. De Geus, Henriette A. Delemarre-van de Waal, Cornelis J. Stam
2013 Brain Connectivity  
Restingstate electroencephalography was recorded from 227 children twice at 5 and 7 years of age.  ...  Constructing a minimum spanning tree (MST) might present a solution, since it does not require setting a threshold and uses a fixed number of nodes and edges.  ...  and the Netherlands Organization for Scientific Research (NWO) (Contract grant numbers: 560-265-052, 575-25-006, 480-04-004), NWO VENI-451-08-026.  ... 
doi:10.1089/brain.2012.0106 pmid:23106635 fatcat:nkenf5c3h5dgnp3aoxiov5v27q

Exploring early human brain development with structural and physiological neuroimaging

Lana Vasung, Esra Abaci Turk, Silvina L. Ferradal, Jason Sutin, Jeffrey N. Stout, Banu Ahtam, Pei-Yi Lin, P. Ellen Grant
2018 NeuroImage  
Instead, one must have a basic understanding of fetal and neonatal structural and physiological brain development, and the important modulators of this process.  ...  In each section we discuss key technical limitations of the imaging modalities and some of the limitations arising due to the biology of the system.  ...  We thank our research scientist Rutvi Vyas and Marie Drottar who carry much of data analysis workload and our large team of research assistants who form the very pillars of our research center.  ... 
doi:10.1016/j.neuroimage.2018.07.041 pmid:30041061 pmcid:PMC6537870 fatcat:nzxrgiebqbdhledw5ierh3arc4

The 9th International Child Neurology Congress The 7th Asian and Oceanian Congress of Child Neurology

2002 Brain & development (Tokyo. 1979)  
We studied this process in organotypic slice cultures derived from the mature (.3-week-old) transgenic mice.  ...  They were followed-up for 5 years. CHI was intravenously injected, 5 ml/day for 1year-old children and 10 ml/day for children older than 1year-old. We defined 3 months as a course of treatment.  ...  Patients in this study consisted of 13 males and six females, aged from 2 years to 13 years and 2 months, of whom 12 cases were beyond 5 years old (63%).  ... 
doi:10.1016/s0387-7604(02)00091-8 fatcat:oq3u62bpkfewhjytujmpwqqgiu

49th Annual Congress of the Canadian Neurological Sciences Federation

2014 Canadian Journal of Neurological Sciences  
Methods: The developmental trajectory of ICNs in 26 children (8-17 years) with focal epilepsy and 28 age-and-sex-matched controls was evaluated using graph theoretical analysis of whole brain connectomes  ...  Methods: The developmental trajectory of ICNs in 26 children (8-17 years) with focal epilepsy and 28 age-and-sex-matched controls was evaluated using graph theoretical analysis of whole brain connectomes  ...  Results: Inflammasome-associated genes, IL-1β, IL-18 and caspase-1, were induced in brains of HIv-infected persons and detected in brain microglial cells.  ... 
doi:10.1017/s0317167100018709 fatcat:465gqktgybball5hywzsmeenqu

Poster Session I

2013 Neuropsychopharmacology  
Results: Thirty-five subjects with a mean age of 50±9 years and 70% Caucasian.  ...  A significant contributor to cognitive impairments seen in SZ may be the elevated levels of kynurenic acid (KYNA), observed in the brains of patients with SZ.  ...  Abi-Dargham, and S. Kapur, Arch Gen Psychiatry 69, 776 (2012). 2  ... 
doi:10.1038/npp.2013.279 fatcat:54ipecxjarcvljrvn5fgtgif5u

3rd Congress of Joint European Neonatal Societies (jENS 2019)

2019 Pediatric Research  
constructed using the Minimum Spanning Tree (MST) method.  ...  MST = Minimum Spanning Tree, EP = extreme prematurely born, VP = very prematurely born 61% for children still followed and from 0 to 15% for children who had no follow-up).  ...  in 2 year cognitive outcomes.  ... 
doi:10.1038/s41390-019-0521-6 fatcat:l5byj4vg4ngqlfk5xmrkxbynne

9TH ECE PROCEEDINGS

2010 Epilepsia  
Purpose: To explore the causative role of PCDH19 gene, located at Xq22, in females with epilepsy.  ...  Results: We included 10 patients (8 boys) aged 2.1-7.8 (median 3.7) years at the time when LTG was started in comedication. The onset of MAE had been at 1.5-4.3 (median 2.6) years.  ...  Seven patients became seizure-free after 28-145 (median 63) days with LTG between 1-7 (median 3) mg/kg and LTG serum levels between 1-5 (median 2) mg/L.  ... 
doi:10.1111/j.1528-1167.2010.02658.x pmid:20590792 fatcat:ylmo7rjtqncydkxeudaib77noy

ACNP 58th Annual Meeting: Poster Session III

2019 Neuropsychopharmacology  
JOTROL resulted in 7-fold greater concentration in rat plasma than nonformulated resveratrol (p < 0.05), and a significant increase in resveratrol concentration in mouse brain.  ...  In 15-month-old 3xTg-AD mice, JOTROL treatment significantly increased both mitochondrial biogenesis (p < 0.05) and ADAM10 expression in the brain (p < 0.01).  ...  and 7 fold; 5-HEPE, derived from the 5-lipoxygenase pathway, was increased 4, 5 and 9 fold, respectively.  ... 
doi:10.1038/s41386-019-0547-9 pmid:31801974 pmcid:PMC6957926 fatcat:dd7d43ysfvc5bbbstfl73szya4

Basque Conference on Cyber Physical Systems and Artificial Intelligence

Manuel Graña
2022 Zenodo  
This entry contains the proceedings of the Basque Conference on Cyber Physical Systems and Artificial Intelligence  ...  In addition, authors thank to the group "Nuevos desarrollos en salud" of Bioaraba and to Osakidetza-Servicio Vasco de Salud for their collaboration.  ...  Acknowledgement The research and development of these projects was carried out in the company Deusto SEIDOR, together with several collaborating companies.  ... 
doi:10.5281/zenodo.7010718 fatcat:a4gzrvtkybdbpmycqmjkvryco4

Basque Conference on Cyber Physical Systems and Artificial Intelligence

Manuel Graña
2022 Zenodo  
This entry contains the proceedings of the Basque Conference on Cyber Physical Systems and Artificial Intelligence  ...  In addition, authors thank to the group "Nuevos desarrollos en salud" of Bioaraba and to Osakidetza-Servicio Vasco de Salud for their collaboration.  ...  Acknowledgement The research and development of these projects was carried out in the company Deusto SEIDOR, together with several collaborating companies.  ... 
doi:10.5281/zenodo.7039276 fatcat:dyorjakurnaxxgvgoojcbpyd5a

Human Hair Graying is Naturally Reversible and Linked to Stress [article]

Ayelet Rosenberg, Shannon Rausser, Junting Ren, Eugene Mosharov, Gabriel M Sturm, R Todd Ogden, Purvi Patel, Rajesh Kumar Soni, Clay Lacefield, Ralf Paus, Martin Picard
2020 bioRxiv   pre-print
Proteomic analysis of matched dark and white hairs replicated across two independent experiments show that graying is marked by the upregulation of proteins related to energy metabolism, mitochondria,  ...  Together, these findings document the reversibility of hair graying in humans and provide a new model to examine the modifiability of human aging.  ...  Acknowledgements This work was supported by the Wharton Fund and NIH grants GM119793 and MH119336 (M.P.).  ... 
doi:10.1101/2020.05.18.101964 fatcat:jyxvpki6zbgh5hb6su2hc45idq

Basque Conference on Cyber Physical Systems and Artificial Intelligence

Manuel Graña
2022 Zenodo  
This entry contains the proceedings of the Basque Conference on Cyber Physical Systems and Artificial Intelligence  ...  This work was supported in part by the Civil Program UAVs Initiative, promoted by the Xunta de Galicia and developed in partnership with the Babcock company.  ...  .; at the UCA: Oscar Pernía, Ignacio Turias; at the US: Ruben Martin Clemente and Sergio Cruces; at the University of Leicester: Yudong Zhang and Shui Hua Wang; and at everywhere: Ana Maria Tomé, Elmar  ... 
doi:10.5281/zenodo.6568145 fatcat:lbwc7clohbeybmmdjhdlalxziu

ACNP 55th Annual Meeting: Poster Session III

2016 Neuropsychopharmacology  
Both 11C-PS13 and 11C-MC1 showed good uptake in monkey brain (peak concentrations of 3-5 SUV) and washed out relatively quickly (demonstrating that the binding was reversible, as expected).  ...  In our presentation last year at the ACNP, we reported a) the pharmacological characterization of the COX-1 and COX-2 radioligands using in vitro enzymatic assays in monkey and human blood, and b) initial  ...  We pursued the community health check-up with every 5-year-old children for three years in Hirosaki-city (2013 Hirosaki-city ( -2015 .  ... 
doi:10.1038/npp.2016.242 fatcat:4efd43swjbboranfrcs3pp32h4

ACNP 57th Annual Meeting: Poster Session II

2018 Neuropsychopharmacology  
Following fear conditioning, mice were sacrificed for further brain and peripheral tissue analysis.  ...  CRP expression across peripheral organs and brain will also be discussed.  ...  Conclusions: The PK parameters for AMPH EROS in children 4-5 years old measured and assessed in this PK study were consistent with those observed in children aged 6 to 12 years and in adults.  ... 
doi:10.1038/s41386-018-0267-6 fatcat:febeq6uwefgdzm65ccmzrmjwjy

Psycho-computational modelling of the mental lexicon [chapter]

Vito Pirrelli, Claudia Marzi, Marcello Ferro, Franco Alberto Cardillo, Harald R. Baayen, Petar Milin
2020 Word Knowledge and Word Usage  
, and for making it possible to publish the present editorial effort as an open access volume with generous funding of the NetWordS project in the years 2011-2015.  ...  We express our hope that similar programmes will continue to be launched and funded in Europe in the years to come.  ...  Thus, whereas the L2-norm of the point (3,-4) is 5, the L1-norm is 7. and Westbury 2010).  ... 
doi:10.1515/9783110440577-002 fatcat:3gntrjuqefg3fk64dvgw253p2i
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