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Anti-U alloimmunisation in a pregnant woman from Niger

Alvaro Ringressi, Sara Biagioni, Giorgio Mello, Gabriele Graziani, Federico Mecacci
2012 Blood Transfusion  
doi:10.2450/2012.0049-11 pmid:22337275 pmcid:PMC3320784 fatcat:ot6zng7kenbcxjqguzk5kyuj6u

Volatile Signals During Pregnancy: A Possible Chemical Basis for Mother–Infant Recognition

Stefano Vaglio, Pamela Minicozzi, Elisabetta Bonometti, Giorgio Mello, Brunetto Chiarelli
2008 Journal of Chemical Ecology  
2009) 'Volatile signals during pregnancy : a possible chemical basis for mother-infant recognition.', Journal of chemical ecology., 35 (1). pp. 131-139. Further information on publisher's website: The full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that: • a full bibliographic reference is made to the original source • a link is made to
more » ... he metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders. Please consult the full DRO policy for further details. Abstract Human pheromones have a role in regulating relationships, and apparently influence partner choice and mother-infant recognition. We analyzed the chemical content of volatiles from sweat patch samples from the para-axillary and nipple-areola regions of women during pregnancy and after childbirth. Solid phase microextraction (SPME) was used to extract the volatile compounds, which were then characterized and quantified by gas chromatography-mass spectrometry (GC-MS). During pregnancy, women developed a distinctive pattern of five volatile compounds common to the para-axillary and nipple-areola regions (1-dodecanol, 1-1΄-oxybis octane, isocurcumenol, α-hexyl-cinnamic aldehyde, and isopropyl myristate). These compounds were absent outside pregnancy and had slightly different patterns in samples from the two body areas. Differentiation of the volatile patterns among pregnant women may help newborns to distinguish their own mothers.
doi:10.1007/s10886-008-9573-5 pmid:19067079 fatcat:tfqalanvfbf7vntl7ne22ynsui

Can the First Fasting Plasma Glucose Test in Pregnancy Predict Subsequent Gestational Complications?

Silvia Burlina, Maria Grazia Dalfrà, Pietro Belloni, Serena Ottanelli, Federico Mecacci, Giorgio Mello, Annunziata Lapolla, Christian S. Goebl
2022 International Journal of Endocrinology  
Objective. To determine the best cut-off level of pregnant women's first fasting plasma glucose (FFPG) test results for the prediction of subsequent onset of gestational diabetes mellitus (GDM) and to examine the association between FFPG and maternal and neonatal outcomes in a large Caucasian population. Methods. 1437 medical records of women with singleton pregnancies followed up between 2015 and 2018 were retrospectively analyzed. Data on FFPG tested in the first trimester and 75 g oral
more » ... e tolerance test (OGTT) findings performed according to IADPSG criteria and Italian guidelines were collected and evaluated. The women's clinical and metabolic characteristics (age, prepregnancy body mass index (BMI), previous pregnancies complicated by GDM, timing of delivery, and gestational hypertension) were also recorded. The fetal variables considered were being large for gestational age (LGA) or small for gestational age (SGA), macrosomia, and hypoglycemia. Results. Among the 1437 pregnant women studied, 684 had a normal glucose tolerance (NGT) and 753 developed GDM. In a univariate analysis FFPG ≥92 mg/dl predicts the risk of GDM with an OR = 2.36 (95% CI 1.930–3.186; p < 0.001 ). In multivariate analysis, after adjusting for principal risk factors of GDM (BMI, previous GDM, age >35 years, family history of diabetes) FFPG ≥92 mg/dl was associated with the risk of GDM (OR = 1.92; 95% CI 1.488–2.492; p < 0.001 ). In univariate analysis, FFPG ≥92 mg/dl predict the risk of insulin therapy in GDM women with a OR = 1.88 (95% CI 1.230–2.066; p < 0.001 ). As regards LGA, in a multivariate analysis, after adjusting for BMI, FFPG ≥92 mg/dl was associated with the risk of LGA only in NGT women (OR = 2.34; 95% CI 1.173–4.574; p = 0.014 ), but not in GDM women. FFPG was not associated with other maternal or neonatal outcomes. Conclusions. FFPG ≥92 mg/dl is related to GDM diagnosis and to the need of insulin therapy if GDM is diagnosed. An early diagnosis and a prompt start of insulin therapy are essential to prevent maternal and fetal complications.
doi:10.1155/2022/9633664 pmid:35449514 pmcid:PMC9017562 fatcat:psjlfx6il5do7hrccm75egxike

Lectin binding in the umbilical cord in altered glycemia

Eleonora Sgambati, Mirca Marini, Giorgia D. Zappoli Thyrion, Debora Vichi, Elena Parretti, Giorgio Mello, Enzo Brizzi, Gherardo Gheri
2007 European Journal of Obstetrics, Gynecology, and Reproductive Biology  
Objective: Content and distribution of the oligosaccharides in the umbilical cord from pregnancies with altered glycemia were investigated. Study design: A prospective cohort study was conducted in the Florence Policlinic of Careggi, Italy. Samples of cord from physiological pregnancies (n = 20), from pregnancies with minor degree of glucose intolerance (n = 20) and from pregnancies with gestational diabetes mellitus (GDM) treated with insulin (n = 20) were collected. Eleven lectins were used
more » ... onA, WGA, PNA, SBA, DBA, LTA, UEA I, OOA, GSL II, MAL II and SNA) in combination with chemical and enzymatic treatments. Results: Increase of N-acetyl-D-glucosamine and a loss of sialic acid in the umbilical cord of the cases with minor degree of glucose intolerance with respect to the other study groups was observed. D-Galactose(b1 ! 3)-N-acetyl-D-galactosamine, N-acetyl-D-galactosamine and L-fucose were in less amount in both the pathological groups with respect to the control one. Conclusion: The increase of some glycoconjugates carbohydrates and the loss of others in the umbilical cord from pregnancies with minor degree of glucose intolerance might be related to its morphofunctional alterations in a not diabetic altered glycemia. Moreover, the treatment with insulin in the GDM might play a role in restoring partially the normal glycosilation in the cord components in the attempt to renew some their functions. #
doi:10.1016/j.ejogrb.2005.12.017 pmid:16442695 fatcat:v72ktvdytjgjhn5rg5rcneu7gi

Elevated insulin sensitivity and β-cell function during pregnancy in mothers of growth-restricted newborns

Maria Grazia Dalfrà, Giovanni Pacini, Elena Parretti, Eugenio Ragazzi, Giorgio Mello, Annunziata Lapolla
2011 American Journal of Physiology. Endocrinology and Metabolism  
The "Barker hypothesis" suggests that low birth weight might predict future risk of developing obesity, cardiovascular disease, and type 2 diabetes. Identification of the causes of fetal growth restriction (FGR) is critical for preventive and management strategies. Some studies indicate that maternal carbohydrate metabolism might be involved in FGR development. We aimed to evaluate, in a large number of normotensive pregnant women with normal glucose tolerance, the effect of insulin sensitivity
more » ... and ␤-cell function on unexplained fetal growth. A total of 1,814 Caucasian pregnant women with normal prepregnancy body mass index were tested with a 75-g, 2-h glucose load (24 -28 gestation wk). Insulin sensitivity was evaluated with fasting (QUICKI) and dynamic index (OGIS) and ␤-cell function with a modified insulinogenic index as ⌬AUCinsulin/⌬AUCglucose and disposition index. FGR was a birth weight below the 5th percentile for gestational age. FGR developed in 99 (5.5%) pregnant women that showed significantly higher QUICKI, OGIS, insulinogenic, and disposition index with respect to women with normal-weight babies (P Ͻ 0.0001). By using multiple regression analysis in the FRG group, QUICKI and OGIS appeared as significant independent variables (P Ͻ 0.0001 and P Ͻ 0.0366, respectively). We conclude that elevated insulin sensitivity seems to be one of the factors involved in determining unexplained fetal growth retardation; its assessment, even only in the fasting state, could be useful to guide any possible monitoring and therapeutic strategies to reduce fetal complications.
doi:10.1152/ajpendo.00024.2011 pmid:21467301 fatcat:piztxxmqk5csjaixegljfc7apy

VEGF expression in the placenta from pregnancies complicated by hypertensive disorders

Eleonora Sgambati, Mirca Marini, Giorgia D. Zappoli Thyrion, Elena Parretti, Giorgio Mello, Claudio Orlando, Lisa Simi, Carmela Tricarico, Gherardo Gheri, Enzo Brizzi
2004 BJOG: an International Journal of Obstetrics and Gynaecology  
doi:10.1111/j.1471-0528.2004.00143.x pmid:15198784 fatcat:swka4c67pjfn7ioylkzkidcjfa

IGF1 as a Potential Treatment for Rett Syndrome: Safety Assessment in Six Rett Patients

Giorgio Pini, Maria Flora Scusa, Laura Congiu, Alberto Benincasa, Paolina Morescalchi, Ilaria Bottiglioni, Pietro Di Marco, Paolo Borelli, Ubaldo Bonuccelli, Andrea Della-Chiesa, Adriele Prina-Mello, Daniela Tropea
2012 Autism Research and Treatment  
Rett syndrome (RTT) is a devastating neurodevelopmental disorder that affects one in ten thousand girls and has no cure. The majority of RTT patients display mutations in the gene that codes for the methyl-CpG-binding protein 2 (MeCP2). Clinical observations and neurobiological analysis of mouse models suggest that defects in the expression of MeCP2 protein compromise the development of the central nervous system, especially synaptic and circuit maturation. Thus, agents that promote brain
more » ... pment and synaptic function, such as insulin-like growth factor 1 (IGF1), are good candidates for ameliorating the symptoms of RTT. IGF1 and its active peptide, (1–3) IGF1, cross the blood brain barrier, and (1–3) IGF1 ameliorates the symptoms of RTT in a mouse model of the disease; therefore they are ideal treatments for neurodevelopmental disorders, including RTT. We performed a pilot study to establish whether there are major risks associated with IGF1 administration in RTT patients. Six young girls with classic RTT received IGF1 subcutaneous injections twice a day for six months, and they were regularly monitored by their primary care physicians and by the unit for RTT in Versilia Hospital (Italy). This study shows that there are no risks associated with IGF1 administration.
doi:10.1155/2012/679801 pmid:22934177 pmcid:PMC3420537 fatcat:bnrsrqf57zbb3pk6oqpivit2b4

Pregnancy disorders leading to very preterm birth influence neonatal outcomes: results of the population-based ACTION cohort study

Luigi Gagliardi, Franca Rusconi, Monica Da Frè, Giorgio Mello, Virgilio Carnielli, Domenico Di Lallo, Francesco Macagno, Silvana Miniaci, Carlo Corchia, Marina Cuttini
2013 Pediatric Research  
doi:10.1038/pr.2013.52 pmid:23493168 fatcat:eofmtsecqzdtbjuhvmiodjcexq

Communication Action Zones in Art and Technology - ZACAT

Camila Dos Santos, Andreia Machado Oliveira, Marcos Steagall
2021 Link Symposium Abstracts 2020  
To support the notion of Art and Communication, authors such as Mario Costa (1936), Fred Forest (1933), Mônica Tavares, Priscila Arantes, Christine Mello and Giselle Beiguelman are based on.  ...  practices are based on the experiences of Brazilian collectives from the 1990's to the present, as seen under the historiography of Art Activism from the 1950's, with Italian autonomist philosophers such as Giorgio  ...  To support the notion of Art and Communication, authors such as Mario Costa (1936 ), Fred Forest (1933) , Mônica Tavares, Priscila Arantes, Christine Mello and Giselle Beiguelman are based on.  ... 
doi:10.24135/link2021.v2i1.101 fatcat:klwvu2ovxjaxlfl4k7nf62vjvm

Relação das pessoas e instituições que doaram obras ou revistas á biblioteca da faculdade no periodo compreendido entre 15 de maio e 15 de agosto de 1934

A Biblioteca
1934 Revista da Faculdade de Direito de São Paulo  
F. de Mello Nogueira J. F. Moreno J. M. de Azevedo Marques J. M.  ...  Niccolo in Siena Oswaldo Aranha Bandeira de Mello Oswaldo Ferraz Alvim Otto Gil Paes Barreto Filho Paulo Américo Passalacqua Paulo C.  ... 
doi:10.11606/issn.2318-8227.v30i3p622-624 fatcat:nybk5gju7ne6zgi4cyhdcrtvhe

Page 393 of National Union Catalog Vol. 47, Issue [page]

1958 National Union Catalog  
The National Union Catalog vasari, Giorgio, 1511-1574. Le vite de’ pih eccellenti pittori, scultori e architetti see Vasari, Giorgio, 1511-1574.  ...  DNLM Vasconcellos Motta, Carlos Carmelo de see Motta, Carlos Carmelo de Vasconcellos, Cardinal Vasconcellos Pereira de Mello, Jose Leite de see Leite de Vasconcellos Pereira de Mello, Jose, 1858-1941.  ... 

High specificity and low sensitivity of ambulatory blood pressure mean for the early diagnosis of hypertension in pregnancy

R Livi
2001 American Journal of Hypertension  
Parretti, Giorgio Mello. 1 Department of Internal Medicine, University of Firenze, Firenze, Italy, 2 Department of Obstetrics and Gynecology, University of Firenze, Firenze, Italy Key Words: blood pressure  ...  Mello. 1 Department of Internal Medicine, University of Firenze, Firenze, Italy, 2 Department of Obstetrics and Gynecology, University of Firenze, Firenze, Italy Riccardo Livi, Laila Teghini, Elena  ... 
doi:10.1016/s0895-7061(01)01514-x fatcat:qrvg6ogfmrepbhhxzr23nltbb4

Blood pressure changes during pregnancy characterize women who will develop gestational hypertension or preeclampsia

R Livi
2001 American Journal of Hypertension  
Riccardo Livi, Laila Teghini, Elena Parretti, Giorgio Mello. 1 Department of Internal Medicine, University of Firenze, Firenze, Italy, 2 Department of Obstetrics and Gynecology, University of Firenze,  ...  Firenze, Italy Riccardo Livi, Laila Teghini, Elena Parretti, Giorgio Mello. 1 Department of Internal Medicine, University of Firenze, Firenze, Italy, 2 Department of Obstetrics and Gynecology, University  ... 
doi:10.1016/s0895-7061(01)01515-1 fatcat:srtusjpufzbrtbzfi3j6mxkvsa

Page 30 of Acta Apostolicae Sedis Vol. 16, Issue 1 [page]

1924 Acta Apostolicae Sedis  
Giorgio Ancel, della medesima archidiocesi. 23 » » Al sig. Francesco Rudman, dell’archidiocesi di Birmingham. 24 » » Al sig.  ...  Tommaso De Gamboa Bandeira De Mello, del patriar- cato di Lisbona. 3 dicembre » Al sig. Giacomo Me. Brien, della diocesi di Southwark. > > » Al sig.  ... 

Page 650 of National Union Catalog Vol. 9, Issue [page]

1963 National Union Catalog  
, xiii, 248 p. illus, 1, Pombal, Sebastido José de Carvalho e Mello, marquez de, 1699-1782, CU NUC67 -36637 Ca Cas Cas'  ...  Castellino, Giorgio Raffaele, 1903- ed, see Bible. O.T. Psalms, Latin, 1960, Vulgate.  ... 
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