A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Filters
Hemispheric specialization within the inferior parietal lobe across cognitive domains
[article]
2020
bioRxiv
pre-print
Preserved Fulltext
The inferior parietal lobe (IPL) is a key neural substrate underlying diverse mental processes, from basic attention to language and social cognition that define human interactions. Its putative domain-global role appears to tie into poorly understood functional differences between both hemispheres. Across attentional, semantic, and social cognitive experiments, our study explored hemispheric specialization within the IPL. The task specificity of IPL subregion activity was substantiated by
doi:10.1101/2020.07.01.181602
fatcat:sptz7j2alrawjd3a6nmyi65tvm
more »
... nct predictive signatures identified by multivariate pattern-learning algorithms. Moreover, the left and right IPL exerted domain-specific modulation of effective connectivity among their subregions. Task-evoked functional interactions of the anterior and posterior IPL subregions involved recruitment of distributed cortical partners. While each anterior IPL subregion was engaged in strongly lateralized coupling links, both posterior subregions showed more symmetric coupling patterns across hemispheres. Our collective results shed light on how under-appreciated lateralization effects within the IPL support some of the most distinctive human mental capacities.
A novel approach to localize cortical TMS effects
[article]
2019
bioRxiv
pre-print
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
F1000Research 2017, 5:1945 (doi:
.12688/f1000research.9277.3)
Siebner HR, Hartwigsen G, Kassuba T, Rothwell JC. ...
doi:10.1101/595603
fatcat:wewzsgoilbbh7lbzkqgonbzwmi
Age-dependent contribution of domain-general network interactions to semantic cognition
[article]
2020
bioRxiv
pre-print
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Aging is characterized by a decline of cognitive control. In semantic cognition, this leads to the paradox that older adults usually show poorer task performance than young adults despite their greater semantic knowledge. So far, the underlying neural changes of these behavioral differences are poorly understood. In the current neuroimaging study, we investigated the interplay of domain-specific and domain-general networks in young and older adults during a verbal semantic fluency task. In both
doi:10.1101/2020.11.06.371153
fatcat:remyxru5pvfpvdmoyr7qinz6iq
more »
... age groups, task processing was characterized by a strong interaction between the domain-general multiple-demand and the default mode system during semantic fluency. However, the behavioral relevance of strengthened connectivity differed between groups: While within- and between-network functional connectivity predicted better performance in young adults, these increases were associated with a performance decline in older adults. Our findings lend novel support to the notion of reduced efficiency in the aging brain, due to neural dedifferentiation in semantic cognition.
Differential contributions of left-hemispheric language regions to basic semantic composition
[article]
2019
bioRxiv
pre-print
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
At the single-word level, Hartwigsen et al. (2015) have shown that left AG and aIFG were able to compensate for a focal disruption of the respective other region induced by transcranial magnetic stimulation ...
In a TMS study, Hartwigsen et al. (2015) showed that temporary disruption of either aIFG or AG alone did not lead to a significant impairment of semantic decisions, while combined TMS over both regions ...
doi:10.1101/2019.12.11.872457
fatcat:joztlosdfvhyticbjdtfybkete
Failure to Improve Verbal Fluency with Transcranial Direct Current Stimulation
2020
Neuroscience
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Hartwigsen / Neuroscience xxx (2020) xxx-xxx Please cite this article in press as: Klaus J, Hartwigsen G. Failure to Improve Verbal Fluency with Transcranial Direct Current Stimulation. ...
Neuroscience (2020), https://doi.org/10.1016/j.neuroscience.2020.09.003
Please cite this article in press as: Klaus J, Hartwigsen G. ...
doi:10.1016/j.neuroscience.2020.09.003
pmid:32946806
fatcat:t752ky555rhfzh2dzorfzr3avy
Task-Specific Network Interactions across Key Cognitive Domains
2022
Cerebral Cortex
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2022; you can also visit the original URL.
The file type is application/pdf.
Aside from this neural specialization, recent work also demonstrates some overlap among these processes in higher association areas (Bzdok, Hartwigsen, et al. 2016) . ...
increased coordination of the task-positive VAN with aDMN and temporal lobe networks, likely ref lecting the support of general semantic processes, which may overlap to some degree for both domains (Bzdok, Hartwigsen ...
doi:10.1093/cercor/bhab531
pmid:35158372
fatcat:mvqly6kqqbf25dslhfkmzmf7p4
Novel Methods to Study Aphasia Recovery after Stroke
[chapter]
2013
Monographs in neural sciences
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Hartwigsen · Siebner [2] . ...
different aspects of language processing, including phonological decisions, reading, and the processing of paralinguistic features such as (emotional) prosody or metaphor processing (for a review, see Hartwigsen ...
doi:10.1159/000346431
pmid:23859969
fatcat:2pxi72t5xfffhd4vzwlnflgaue
Neural modelling of the semantic predictability gain under challenging listening conditions
[article]
2019
bioRxiv
pre-print
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
. /2019 exhibit functional relevance in mediating the comprehension gain (Hartwigsen et al., 2015) , this region has been proposed to serve top-down activation of semantic concepts that facilitate speech ...
reported a decrease in the functional connectivity between left IFG and right insula under facilitatory neurostimulation that was associated with improved word learning (Fiori, Kunz, Kuhnke, Marangolo, & Hartwigsen ...
doi:10.1101/2019.12.20.872614
fatcat:wy6ejlomyzhxlert6jvcnpkimm
Multivariate single-subject analysis of short-term reorganization in the language network
2018
Cortex
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
To cite this version: Gesa Hartwigsen, Danilo Bzdok. Multivariate single-subject analysis of short-term reorganization in the language network. Cortex, Elsevier, 2018, pp. ...
Here, we re-analyzed data from our recent study (Hartwigsen et al., 2017 ) that investigated functional reorganization in the language network. ...
Combining focal perturbations induced by transcranial magnetic stimulation (TMS) and fMRI in the healthy brain, we recently provided insight into the reorganization potential of language networks (Hartwigsen ...
doi:10.1016/j.cortex.2018.06.013
pmid:30057248
fatcat:exi7ckffh5gjnakoewmnek2vsu
A novel approach to localize cortical TMS effects
2019
NeuroImage
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Gesa Hartwigsen: Conceptualization, Resources, Writing -Original Draft, Supervision, Project administration, Funding acquisition. ...
may assist the neurobiological interpretation of TMS effects and aid the localization of the effectively stimulated cortical area that underlies the observed physiological or behavioral effect (see Hartwigsen ...
doi:10.1016/j.neuroimage.2019.116486
pmid:31877374
fatcat:auqp4hppwnee5l6oiqatrw3gra
Task-Dependent Functional and Effective Connectivity during Conceptual Processing
2021
Cerebral Cortex
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
functional magnetic resonance imaging (fMRI) study revealed that both modality-specific and multimodal regions respond to sound and action features of concepts in a task-dependent fashion (Kuhnke P, Kiefer M, Hartwigsen ...
Such compensatory mechanisms could be further investigated in future studies employing combined TMS-fMRI (Hartwigsen 2018) . ...
doi:10.1093/cercor/bhab026
pmid:33677479
pmcid:PMC8196308
fatcat:me3heakxobaefimirt3jatmseu
Predicting speech from a cortical hierarchy of event-based timescales
[article]
2020
bioRxiv
pre-print
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
How can anticipatory neural processes structure the temporal unfolding of context in our natural environment? We here provide evidence for a neural coding scheme that sparsely updates contextual representations at the boundary of events and gives rise to a hierarchical, multi-layered organization of predictive language comprehension. Training artificial neural networks to predict the next word in a story at five stacked timescales and then using model-based functional MRI, we observe a sparse,
doi:10.1101/2020.12.19.423616
fatcat:r4dwhe23kzb6tnau2n5sjlvere
more »
... vent-based 'surprisal hierarchy'. The hierarchy evolved along a temporo-parietal pathway, with model-based surprisal at longest timescales represented in inferior parietal regions. Along this hierarchy, surprisal at any given timescale gated bottom-up and top-down connectivity to neighbouring timescales. In contrast, surprisal derived from a continuously updated context influenced temporo-parietal activity only at short timescales. Representing context in the form of increasingly coarse events constitutes a network architecture for making predictions that is both computationally efficient and semantically rich.
Adaptive Plasticity in the Healthy Language Network: Implications for Language Recovery after Stroke
2016
Neural Plasticity
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
Recently, we combined TMS and fMRI to investigate adaptive plasticity in the semantic network after focal perturbation of a key semantic area prior to task processing (Hartwigsen et al., unpublished data ...
doi:10.1155/2016/9674790
pmid:27830094
pmcid:PMC5088318
fatcat:qqmwczphgneztao62jbi2stbkq
Rapid short-term reorganization in the language network
2017
eLife
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
Author ORCIDs Gesa Hartwigsen, http://orcid.org/0000-0002-8084-1330 Danilo Bzdok, http://orcid.org/0000-0003-3466-6620
Ethics Human subjects: Written informed consent was obtained before the experiment.The ...
The stimuli were taken from a previous study (Hartwigsen et al., 2010) . ...
Hartwigsen et al. examined how this affected the volunteers' performance on a language task, as well as the activity of other language areas. ...
doi:10.7554/elife.25964
pmid:28537558
pmcid:PMC5472437
fatcat:ddvqis763zcqjfxzslgrpw44fy
Editorial: Modulating Cortical Dynamics in Language, Speech and Music
2018
Frontiers in Integrative Neuroscience
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
., 1999; Walsh and Cowey, 2000; Kuo and Nitsche, 2012) and allow for an investigation of adaptive network dynamics on the systems level (Hartwigsen, 2018) . ...
doi:10.3389/fnint.2018.00058
pmid:30538623
pmcid:PMC6277569
fatcat:5n7p3oxllbhnjoqfyvqurtokle
« Previous
Showing results 1 — 15 out of 61 results