Filters








4 Hits in 9.1 sec

Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome features

Derek Huntley, Y Amy Tang, Tatyana B Nesterova, Sarah Butcher, Neil Brockdorff
<span title="">2008</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/n5zrklrhlzhtdorf4rk4rmeo3i" style="color: black;">BMC Bioinformatics</a> </i> &nbsp;
Results: We developed the Genome Environment Browser (GEB) in order to visualise the integration of experimental data from large scale high throughput analyses with repeat sequence features that define  ...  Conclusion: The Genome Environment Browser is a versatile program which can be easily adapted for displaying all types of genome data with known genomic coordinates. It is currently available at  ...  Acknowledgements This project was funded in part by the Medical Research Council, UK. YAT was supported by an MRC Pre-doctoral fellowship.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/1471-2105-9-501">doi:10.1186/1471-2105-9-501</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/19038045">pmid:19038045</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2614995/">pmcid:PMC2614995</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cmqqf3rqvrh37o44btpitfatcq">fatcat:cmqqf3rqvrh37o44btpitfatcq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170830102618/https://bmcbioinformatics.biomedcentral.com/track/pdf/10.1186/1471-2105-9-501?site=http://bmcbioinformatics.biomedcentral.com" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ec/cf/eccf55f9b14451ecd84e7c7f638a264fbdab3200.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/1471-2105-9-501"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614995" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation

Y Amy Tang, Derek Huntley, Giovanni Montana, Andrea Cerase, Tatyana B Nesterova, Neil Brockdorff
<span title="">2010</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/t46dy4kadfdgbm52javmafxiyy" style="color: black;">Epigenetics &amp; Chromatin</a> </i> &nbsp;
To determine the requirements for efficient silencing we have analysed the relationship of chromosome features, including L1 repeats, and the extent of silencing in cell lines carrying inducible Xist transgenes  ...  L1-dense domains as a major influence on the ability of Xist-mediated silencing to be propagated in a continuous manner in cis.  ...  Acknowledgements We would like to thank the members of the CSC microarray facility for technical assistance and members of the lab for helpful discussion.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/1756-8935-3-10">doi:10.1186/1756-8935-3-10</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20459652">pmid:20459652</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2873326/">pmcid:PMC2873326</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/txucmeehcrfnnjq67v5hgi4lqm">fatcat:txucmeehcrfnnjq67v5hgi4lqm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180721163950/https://epigeneticsandchromatin.biomedcentral.com/track/pdf/10.1186/1756-8935-3-10?site=epigeneticsandchromatin.biomedcentral.com" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/45/73/4573efd28edb2945b33cb8e0818199d61a0d6d1e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/1756-8935-3-10"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873326" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Liprotides: a New Class of Protein Lipid-Complexes

Jannik N. Pedersen, Henriette Kristina S. Frislev, Jan S. Pedersen, Daniel E. Otzen
<span title="">2016</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/dez2wau7t5aqvklzwrcsreuwq4" style="color: black;">Biophysical Journal</a> </i> &nbsp;
It is also possible to optimize the set of parameters describing the models by the fitting of the theoretical intensity against experimental data.  ...  , Python based beamline control, web based applications for data acquisition and analysis, virtualization, and new sample environments.  ...  The Pilatus 1M detector (Dectris) is mounted for data collection characterized with a high dynamic range and a short readout time.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.bpj.2015.11.3085">doi:10.1016/j.bpj.2015.11.3085</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/eqeeb47atfc4lisnurb25n55gu">fatcat:eqeeb47atfc4lisnurb25n55gu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180721074837/https://www.helmholtz-berlin.de/media/media/spezial/events/sas/2015/Programme/Abstracts/Update_14_Sept/poster_book_a4_fin_140915.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.bpj.2015.11.3085"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

Chromatin folding in health and disease: exploring allele-specific topologies and the reorganization due to the 16p11.2 deletion in autism-spectrum disorder

Rieke Kempfer, Humboldt-Universität Zu Berlin
<span title="2020-11-09">2020</span>
The collection of this data was accompanied by the development of a high-throughput version of GAM that allows the generation of large datasets.  ...  For the exploration of inter-chromosomal contacts in disease, I mapped chromatin interactions with Hi-C in the context of a CNV at the human 16p11.2 locus, associated with autism spectrum disorders.  ...  The collection of this data was accompanied by the development of a high-throughput version of GAM that allows the generation of large datasets.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.18452/22071">doi:10.18452/22071</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/gim2f2zeubgkhdo6igmsgrv6l4">fatcat:gim2f2zeubgkhdo6igmsgrv6l4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201115121956/https://edoc.hu-berlin.de/bitstream/handle/18452/22777/dissertation_kempfer_rieke.pdf;jsessionid=2BE44263ACA7AE5CBF2EB3A54F3A0C67?sequence=5" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/05/86/0586df866dbcb47c61b7be37444af44cf78f14ad.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.18452/22071"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>