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Genetics of primary cerebral gyrification: Heritability of length, depth and area of primary sulci in an extended pedigree of Papio baboons

P. Kochunov, D.C. Glahn, P.T. Fox, J.L. Lancaster, K. Saleem, W. Shelledy, K. Zilles, P.M. Thompson, O. Coulon, J.F. Mangin, J. Blangero, J. Rogers
2010 NeuroImage  
Our measures were surface area, and average length and depth of eleven primary cortical sulci from high-resolution MR images in 180 pedigreed baboons.  ...  Average heritability values for sulcal area, depth and length (h 2 Area = .38 ± .22; h 2 Depth = .42 ± .23; h 2 Length = .34 ± .22) indicated that regional cortical anatomy is under genetic control.  ...  In the current study, we measure sulcal area, length and depth from high-resolution MR imaging from 180 pedigreed Papio baboons (Papio hamadryas).  ... 
doi:10.1016/j.neuroimage.2009.12.045 pmid:20035879 pmcid:PMC2888833 fatcat:7mybpcuy2vdfrgl5myiyfrd4oq

Cortical Folding of the Primate Brain: An Interdisciplinary Examination of the Genetic Architecture, Modularity, and Evolvability of a Significant Neurological Trait in Pedigreed Baboons (Genus Papio )

Elizabeth G. Atkinson, Jeffrey Rogers, Michael C. Mahaney, Laura A. Cox, James M. Cheverud
2015 Genetics  
An extended description and rationale for each covariate is 207 provided in Supporting Materials. 208 209 Quantitative genetics and creation of correlation matrices 210 Heritability (h 2 ) estimates and  ...  The lengths of seven of the ten landmark sulci were significantly heritable -all but 354 iar, sar, and spcd.  ... 
doi:10.1534/genetics.114.173443 pmid:25873632 pmcid:PMC4492386 fatcat:fc7ez5esafg4xja3d7dgofylx4

Development of structural MR brain imaging protocols to study genetics and maturation

Peter Kochunov, Michael Duff Davis
2010 Methods  
Finally, recent findings in the genetics of cerebral gyrification and tracking of maturation trends in the fetal, newborn and adult brain are described  ...  The sizes of cortical gyri and sulci scale allometrically with brain size.  ...  This work was supported, in part, by the National Institute of Biomedical Imaging and Bioengineering (K01 #EB006395) grant to PK, the SNPRC (NIH #P51-RR013986) and the NIH/NCRR (#1R01AG029412-01) grants  ... 
doi:10.1016/j.ymeth.2009.08.002 pmid:19665566 pmcid:PMC2828529 fatcat:rx4qaijpc5fspnkcbcj76ea2jm

The reliability and heritability of cortical folds and their genetic correlations across hemispheres

Fabrizio Pizzagalli, Guillaume Auzias, Qifan Yang, Samuel R. Mathias, Joshua Faskowitz, Joshua D. Boyd, Armand Amini, Denis Rivière, Katie L. McMahon, Greig I. de Zubicaray, Nicholas G. Martin, Jean-François Mangin (+6 others)
2020 Communications Biology  
Variations in the length, depth, width, and surface area of these sulcal landmarks have been associated with disease, and may be genetically mediated.  ...  Overall, sulcal width was the most heritable metric, and earlier forming sulci showed higher heritability.  ...  The image processing protocol developed for this work is available at http://enigma.ini. usc.edu/protocols/imaging-protocols/ (ENIGMA-Sulci).  ... 
doi:10.1038/s42003-020-01163-1 pmid:32934300 fatcat:mdefl6v23nepdonhqpgxwyhdsi

Behavioral and brain asymmetries in primates: a preliminary evaluation of two evolutionary hypotheses

William D. Hopkins, Maria Misiura, Sarah M. Pope, Elitaveta M. Latash
2015 Annals of the New York Academy of Sciences  
Lastly, we discuss some of the challenges in the study of hemispheric specialization in primates and offer some suggestions on how to advance the field.  ...  Specifically, we first discuss the evidence of that genes play specific roles in determining leftright differences in anatomical and functional asymmetries in primates.  ...  We would like to thank Yerkes National Primate Research Center and The University of Texas MD Anderson Cancer Center and their respective veterinary and care staffs for assistance in collection of the  ... 
doi:10.1111/nyas.12936 pmid:26426409 pmcid:PMC4715693 fatcat:gfqakz7kg5ftndnbifzheeso7i