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Genetics of primary cerebral gyrification: Heritability of length, depth and area of primary sulci in an extended pedigree of Papio baboons
2010
NeuroImage
Our measures were surface area, and average length and depth of eleven primary cortical sulci from high-resolution MR images in 180 pedigreed baboons. ...
Average heritability values for sulcal area, depth and length (h 2 Area = .38 ± .22; h 2 Depth = .42 ± .23; h 2 Length = .34 ± .22) indicated that regional cortical anatomy is under genetic control. ...
In the current study, we measure sulcal area, length and depth from high-resolution MR imaging from 180 pedigreed Papio baboons (Papio hamadryas). ...
doi:10.1016/j.neuroimage.2009.12.045
pmid:20035879
pmcid:PMC2888833
fatcat:7mybpcuy2vdfrgl5myiyfrd4oq
Cortical Folding of the Primate Brain: An Interdisciplinary Examination of the Genetic Architecture, Modularity, and Evolvability of a Significant Neurological Trait in Pedigreed Baboons (Genus Papio )
2015
Genetics
An extended description and rationale for each covariate is 207 provided in Supporting Materials. 208 209 Quantitative genetics and creation of correlation matrices 210 Heritability (h 2 ) estimates and ...
The lengths of seven of the ten landmark sulci were significantly heritable -all but 354 iar, sar, and spcd. ...
doi:10.1534/genetics.114.173443
pmid:25873632
pmcid:PMC4492386
fatcat:fc7ez5esafg4xja3d7dgofylx4
Development of structural MR brain imaging protocols to study genetics and maturation
2010
Methods
Finally, recent findings in the genetics of cerebral gyrification and tracking of maturation trends in the fetal, newborn and adult brain are described ...
The sizes of cortical gyri and sulci scale allometrically with brain size. ...
This work was supported, in part, by the National Institute of Biomedical Imaging and Bioengineering (K01 #EB006395) grant to PK, the SNPRC (NIH #P51-RR013986) and the NIH/NCRR (#1R01AG029412-01) grants ...
doi:10.1016/j.ymeth.2009.08.002
pmid:19665566
pmcid:PMC2828529
fatcat:rx4qaijpc5fspnkcbcj76ea2jm
The reliability and heritability of cortical folds and their genetic correlations across hemispheres
2020
Communications Biology
Variations in the length, depth, width, and surface area of these sulcal landmarks have been associated with disease, and may be genetically mediated. ...
Overall, sulcal width was the most heritable metric, and earlier forming sulci showed higher heritability. ...
The image processing protocol developed for this work is available at http://enigma.ini. usc.edu/protocols/imaging-protocols/ (ENIGMA-Sulci). ...
doi:10.1038/s42003-020-01163-1
pmid:32934300
fatcat:mdefl6v23nepdonhqpgxwyhdsi
Behavioral and brain asymmetries in primates: a preliminary evaluation of two evolutionary hypotheses
2015
Annals of the New York Academy of Sciences
Lastly, we discuss some of the challenges in the study of hemispheric specialization in primates and offer some suggestions on how to advance the field. ...
Specifically, we first discuss the evidence of that genes play specific roles in determining leftright differences in anatomical and functional asymmetries in primates. ...
We would like to thank Yerkes National Primate Research Center and The University of Texas MD Anderson Cancer Center and their respective veterinary and care staffs for assistance in collection of the ...
doi:10.1111/nyas.12936
pmid:26426409
pmcid:PMC4715693
fatcat:gfqakz7kg5ftndnbifzheeso7i