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Field Splitting Problems in Intensity-Modulated Radiation Therapy [chapter]

Danny Z. Chen, Chao Wang
2006 Lecture Notes in Computer Science  
In this paper, we consider a set of geometric and combinatorial problems that arise in IMRT planning and delivery, such as static leaf sequencing, static leaf sequencing with error control, field splitting  ...  We discuss efficient algorithms for these problems.  ...  Leaf Sequencing for Dynamic IMRT and Arc Modulated Radiation Therapy In this section, we study the dynamic leaf sequencing problem and the single-arc leaf sequencing problem, i.e., the leaf sequencing  ... 
doi:10.1007/11940128_69 fatcat:5atvqhymi5aetaxakgqlgde2xm

Arc-modulated radiation therapy (AMRT): a single-arc form of intensity-modulated arc therapy

Chao Wang, Shuang Luan, Grace Tang, Danny Z Chen, Matt A Earl, Cedric X Yu
2008 Physics in Medicine and Biology  
In this paper, we present a treatment planning scheme for AMRT, which addresses the challenges in inverse planning, leaf sequencing and dose calculation.  ...  therapy (AMRT) is a novel rotational intensitymodulated radiation therapy (IMRT) technique developed for a clinical linear accelerator that aims to deliver highly conformal radiation treatment using just  ...  Acknowledgments The authors would like to thank the anonymous reviewers for their thoughtful comments.  ... 
doi:10.1088/0031-9155/53/22/002 pmid:18936519 fatcat:z4bxz5fwhbbp5bgjjtmttje54i

Intensity-modulated radiation therapy: a review with a physics perspective

Byungchul Cho
2018 Radiation Oncology Journal  
Intensity-modulated radiation therapy (IMRT) has been considered the most successful development in radiation oncology since the introduction of computed tomography into treatment planning that enabled  ...  More than three decades have passed since the concept of inverse planning was first introduced in 1982, and IMRT has become the most important and common modality in radiation therapy.  ...  In 1992, Convery and Rosenbloom [18] developed an outstanding 'leaf sequencing' approach that allowed arbitrary intensity profiles to be produced by a unidirectional 'sweep' motion of the MLC leaves  ... 
doi:10.3857/roj.2018.00122 pmid:29621869 pmcid:PMC5903356 fatcat:nzkbrqv3k5djjlokxgslxfukte

IMRT: delivery techniques and quality assurance

P C Williams
2003 British Journal of Radiology  
Intensity modulated radiotherapy (IMRT) is a major development in the delivery of radiation therapy that has the potential to improve patient outcome by reducing morbidity or increasing local tumour control  ...  It demonstrates that the technology is mature and sufficiently well understood so that IMRT can be safely implemented in the general clinical environment rather than being limited to application in the  ...  However the problem of geometrically small segments remains.  ... 
doi:10.1259/bjr/12907222 pmid:14623777 fatcat:abtweythpzawhjtnb2j27gc5by

IMRT: a review and preview

Thomas Bortfeld
2006 Physics in Medicine and Biology  
The very first cornerstone paper on intensity-modulated radiation therapy (IMRT) was published in Physics in Medicine and Biology, and many seminal IMRT works have since appeared in this journal.  ...  Today IMRT is a widely used clinical treatment modality in many countries.  ...  Acknowledgment I am grateful to Steve Webb for his helpful comments on the manuscript. I would like to thank Wolfgang Schlegel, Art Boyer, and Michael Patterson for their feedback and useful input.  ... 
doi:10.1088/0031-9155/51/13/r21 pmid:16790913 fatcat:zgjodh2mnvctrlztctlqrmy4ou

The use of EPID-measured leaf sequence files for IMRT dose reconstruction in adaptive radiation therapy

Louis Lee, Weihua Mao, Lei Xing
2008 Medical Physics (Lancaster)  
The approach also allows users who do not have access to MLC log files to probe the actual IMRT delivery and translate the information gained for dose reconstruction in adaptive radiation therapy.  ...  a leaf sequence ͑LS͒ file based on the leaf end positions calculated from the MLC segments and their associated fractional monitor units.  ...  INTRODUCTION An advantage of the fractionation scheme in radiation treatment is that it offers room for adaptive radiation therapy ͑ART͒.  ... 
doi:10.1118/1.2990782 pmid:19070236 pmcid:PMC2737246 fatcat:72yecaattvhg3d6wx4xo2nlyt4

Intensity-modulated arc therapy: principles, technologies and clinical implementation

Cedric X Yu, Grace Tang
2011 Physics in Medicine and Biology  
However, there remains a lack of general understanding for the planning of such arc treatments, as well as what delivery limitations and compromises are made.  ...  In recent years, single-arc forms of IMAT have emerged and become commercially adopted.  ...  Acknowledgement The work is supported, in part, by the NIH/NCI grant no R01CA117997.  ... 
doi:10.1088/0031-9155/56/5/r01 pmid:21297245 fatcat:c2drmskatjhbpgrr3y625aodde

From analytic inversion to contemporary IMRT optimization: Radiation therapy planning revisited from a mathematical perspective

Yair Censor, Jan Unkelbach
2012 Physica medica (Testo stampato)  
Historically, planning for Intensity-Modulated Radiation Therapy (IMRT) has been considered as an inverse problem.  ...  In this paper we look at the development of radiation therapy treatment planning from a mathematical point of view.  ...  therapy treatment planning and other inverse problems.  ... 
doi:10.1016/j.ejmp.2011.04.002 pmid:21616694 pmcid:PMC3164927 fatcat:i4hrzfkpzndbho7cgolsm2bqka

Technological quality requirements for stereotactic radiotherapy

Daniela Schmitt, Oliver Blanck, Tobias Gauer, Michael K. Fix, Thomas B. Brunner, Jens Fleckenstein, Britta Loutfi-Krauss, Peter Manser, Rene Werner, Maria-Lisa Wilhelm, Wolfgang W. Baus, Christos Moustakis
2020 Strahlentherapie und Onkologie (Print)  
Additionally, further research and development needs in terms of insufficient data and unsolved problems for stereotactic radiotherapy are identified, which will serve as a basis for the future assignments  ...  of the DGMP Working Group for Physics and Technology in Stereotactic Radiotherapy.  ...  K K Each MRI sequence should be corrected for geometric distortions in the intrinsic imaging processing method of the MRI scanner (with a 3D approach if possible).  ... 
doi:10.1007/s00066-020-01583-2 pmid:32211939 fatcat:qg7jdiwjdrdlxi5mtwydq3snfy

Inverse Treatment Planning for Radiation Therapy Based on Fast Monte Carlo Dose Calculation [chapter]

M. Fippel, M. Alber, M. Birkner, W. Laub, F. Nüsslin, I. Kawrakow
2001 Advanced Monte Carlo for Radiation Physics, Particle Transport Simulation and Applications  
The corresponding techniques, whose implementation is the subject for future work, are also presented here.  ...  It allows optimisation of intensity modulated dose distributions in 15 to 60 minutes on present day personal computers.  ...  Dynamic Multi Leaf Collimators An alternative method to deliver intensity modulated beam profiles in radiation therapy is the use of dynamic multi-leaf collimators (DMLC).  ... 
doi:10.1007/978-3-642-18211-2_36 fatcat:lfuv773ygvhl5fj7xg25j3fwgq

Simultaneous delivery time and aperture shape optimization for the volumetric-modulated arc therapy (VMAT) treatment planning problem

Mehdi Mahnam, Michel Gendreau, Nadia Lahrichi, Louis-Martin Rousseau
2017 Physics in Medicine and Biology  
In this paper, we propose a novel heuristic algorithm for the volumetric-modulated arc therapy (VMAT) treatment planning problem, optimizing the trade-off between delivery time and treatment quality.  ...  Our heuristic is based on column generation; the aperture configuration is modeled in the columns and the dose distribution and time restriction in the rows.  ...  Similar to intensity modulated radiation therapy (IMRT), the beams are formed by a multi-leaf collimator (MLC).  ... 
doi:10.1088/1361-6560/aa7447 pmid:28524822 fatcat:yz5ihandxrfqvbr7zzw6qljrwe

Multi-criteria optimization methods in radiation therapy planning: a review of technologies and directions [article]

David Craft
2013 arXiv   pre-print
We review the field of multi-criteria optimization for radiation therapy treatment planning.  ...  Once a high quality solution is selected from the Pareto surface, a sparse version (which can mean fewer beams, fewer segments, less leaf travel for arc therapy techniques, etc.) is obtained using an appropriate  ...  This approach is logical for radiation therapy planning problems in that its first focus is on achieving a plan of good balance between target coverage and healthy organ sparing.  ... 
arXiv:1305.1546v1 fatcat:qgfgrxhpxrbqnpvze6uvq7waw4

A new MLC segmentation algorithm/software for step-and-shoot IMRT delivery

Shuang Luan, Chao Wang, Danny Z. Chen, Xiaobo S. Hu, Shahid A. Naqvi, Cedric X. Yu, Chad L. Lee
2004 Medical Physics (Lancaster)  
Our new segmentation algorithm, called SLS ͑an abbreviation for static leaf sequencing͒, is based on graph algorithmic techniques in computer science.  ...  Elekta SL 20 Linac system in contrast to the 72 min for the CORVUS 4.0 sequences ͑a three-fold improvement͒.  ...  The work of the first author was also supported in part by a fellowship from the Center for Applied Mathematics at the University of Notre Dame.  ... 
doi:10.1118/1.1646471 pmid:15124986 fatcat:ktts2wzabzewxit4774tzqsf4a

Planning and delivery of intensity-modulated radiation therapy

Cedric X. Yu, Christopher J. Amies, Michelle Svatos
2008 Medical Physics (Lancaster)  
Intensity modulated radiation therapy ͑IMRT͒ is an advanced form of external beam radiation therapy.  ...  IMRT offers an additional dimension of freedom as compared with field shaping in threedimensional conformal radiation therapy because the radiation intensities within a radiation field can be varied according  ...  Ensuring such connectedness of adjacent subfields for smooth leaf motion is of great concern in the leaf sequencing algorithm for IMAT. 13,14 Effective planning tools for IMAT have only been developed  ... 
doi:10.1118/1.3002305 pmid:19175082 fatcat:7eatvejoqzhcnduklcokjgukoq

Combining segment generation with direct step-and-shoot optimization in intensity-modulated radiation therapy

Fredrik Carlsson
2008 Medical Physics (Lancaster)  
A method for generating a sequence of intensity-modulated radiation therapy step-and-shoot plans with increasing number of segments is presented.  ...  The segment generation is based on a column generation approach.  ...  Acknowledgements I thank Anders Forsgren for many helpful discussions on the mathematical aspects of this problem.  ... 
doi:10.1118/1.2964096 pmid:18841833 fatcat:uqesppum5vglngyrz5cdg7b5um
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